Copper Depletion Down-regulates Expression of the Alzheimer's Disease Amyloid-β Precursor Protein Gene

Journal of Biological Chemistry

Volumn 279, Issue 19, 2004, Pages 20378-20386

  Bellingham, Shayne A ^a   Lahiri, Debomoy K ^b   Maloney, Bryan ^b   La Fontaine, Sharon ^c   Multhaup, Gerd ^d   Camakaris, James ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DEAKIN UNIVERSITY   (Australia)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; DATA REDUCTION; DISEASES; GENES; PROTEINS; REDUCTION; TOXIC MATERIALS;

GENE EXPRESSION; HOMEOSTASIS; NEUROPATHOGENESIS; PRECURSORS;

BIOCHEMISTRY;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; COPPER; MENKES PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; APP GENE; ARTICLE; CHELATION; CONTROLLED STUDY; COPPER METABOLISM; DELETION MUTANT; FIBROBLAST; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NEUROPATHOLOGY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION;

ADENOSINE TRIPHOSPHATASES; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BETA-GALACTOSIDASE; BLOTTING, NORTHERN; CATION TRANSPORT PROTEINS; CELLS, CULTURED; CHLORAMPHENICOL O-ACETYLTRANSFERASE; COMPUTATIONAL BIOLOGY; COPPER; DOWN-REGULATION; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE DELETION; GENETIC VECTORS; HUMANS; IRON; MACACA MULATTA; PEPTIDES; PLASMIDS; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; TRANSFECTION; ZINC;

MAMMALIA;

EID: 2442586535     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400805200     Document Type: Article

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