A multifunctional, neuroprotective drug, ladostigil (TV3326), regulates holo-APP translation and processing

FASEB Journal

Volumn 20, Issue 12, 2006, Pages

  Yogev Falach, Merav ^a   Bar Am, Orit ^a   Amit, Tamar ^a   Weinreb, Orly ^a   Youdim, Moussa B H ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

secretase; Acetylcholinesterase inhibitor; Alzheimer disease; Amyloid precursor protein

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CASPASE 3; GENERIC DRUG; LADOSTIGIL; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE C; RASAGILINE; (N PROPARGYL (3R) AMINOINDAN 5 YL) ETHYL METHYL CARBAMATE; (N-PROPARGYL-(3R) AMINOINDAN-5-YL)-ETHYL METHYL CARBAMATE; AMINE OXIDASE (FLAVIN CONTAINING); CASP3 PROTEIN, HUMAN; CASPASE; INDAN DERIVATIVE; MESSENGER RNA; NEUROPROTECTIVE AGENT;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; HUMAN CELL; NEUROBLASTOMA; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; ALZHEIMER DISEASE; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PROTEIN PROCESSING; PROTEIN SYNTHESIS; RNA PROCESSING; TUMOR CELL LINE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; APOPTOSIS; CASPASE 3; CASPASES; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; HUMANS; INDANS; MONOAMINE OXIDASE; NEUROBLASTOMA; NEUROPROTECTIVE AGENTS; PROTEIN BIOSYNTHESIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER;

EID: 33845669856     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.05-4910fje     Document Type: Article

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