Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts

Journal of Neurochemistry

Volumn 91, Issue 2, 2004, Pages 423-428

  Bellingham, Shayne A ^a   Ciccotosto, Giuseppe D ^a   Needham, B Elise ^a   Fodero, Lisa R ^a   White, Anthony R ^a   Masters, Colin L ^a   Cappai, Roberta ^a   Camakaris, James ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Amyloid precursor like protein 2; Cortical neurons; Gene knockout out mice; Neuronal copper homeostasis

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR LIKE PROTEIN 1; AMYLOID PRECURSOR LIKE PROTEIN 2; AMYLOID PRECURSOR PROTEIN; BINDING PROTEIN; COPPER; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN CELL; CONTROLLED STUDY; COPPER METABOLISM; EMBRYO; FIBROBLAST; GENE OVEREXPRESSION; HOMEOSTASIS; KNOCKOUT GENE; MOUSE; MULTIGENE FAMILY; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; COPPER; COPPER RADIOISOTOPES; DISEASE MODELS, ANIMAL; FIBROBLASTS; GENE EXPRESSION; HOMEOSTASIS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEURONS;

ANIMALIA; MUS MUSCULUS;

EID: 5444235015     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02731.x     Document Type: Article

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