Neuronal Zinc Exchange with the Blood Vessel Wall Promotes Cerebral Amyloid Angiopathy in an Animal Model of Alzheimer's Disease

Journal of Neuroscience

Volumn 24, Issue 13, 2004, Pages 3453-3459

  Friedlich, Avi L ^a   Lee, Joo Yong ^b   Van Groen, Thomas ^c   Cherny, Robert A ^d,e   Volitakis, Irene ^d,e   Cole, Toby B ^f   Palmiter, Richard D ^f   Koh, Jae Young ^b   Bush, Ashley I ^a,d,e  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b University of Ulsan College of Medicine   (South Korea)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer; Amyloid; Blood brain; Cerebrovasculature; Congophilic angiopathy; Neuropathology; Synapse; Zinc

Indexed keywords

AMYLOID BETA PROTEIN; CARRIER PROTEIN; N (6 METHOXY 8 QUINOLYL) 4 CARBOXYBENZOYLSULFONAMIDE; SULFONAMIDE; UNCLASSIFIED DRUG; ZINC; ZINC TRANSPORTER 3;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL WALL; BRAIN HEMORRHAGE; CONTROLLED STUDY; DEMENTIA; FEMALE; GENE DISRUPTION; GENE TARGETING; HUMAN; IMMUNOHISTOCHEMISTRY; MOUSE; NEOCORTEX; NEUROPATHOLOGY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SYNAPSE; SYNAPTIC MEMBRANE; TRANSGENIC MOUSE; VASCULAR AMYLOIDOSIS;

ALZHEIMER DISEASE; ANIMALS; BLOOD VESSELS; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; CEREBRAL AMYLOID ANGIOPATHY; COPPER; DISEASE MODELS, ANIMAL; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; NEOCORTEX; ORGAN SPECIFICITY; SYNAPSES; ZINC;

EID: 1842506368     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0297-04.2004     Document Type: Article

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