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Volumn 112, Issue 8, 2008, Pages 3283-3292

Development of regulatory T cells requires IL-7Rά stimulation by IL-7 or TSLP

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; CD4 ANTIGEN; CD45RB ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR ALPHA; L SELECTIN; STAT5 PROTEIN; THYMIC STROMAL LYMPHOPOIETIN; TRANSCRIPTION FACTOR FOXP3; CYTOKINE; INTERLEUKIN 7 RECEPTOR; INTERLEUKIN 7 RECEPTOR, ALPHA CHAIN; INTERLEUKIN-7 RECEPTOR, ALPHA CHAIN;

EID: 54049129701     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-02-137414     Document Type: Article
Times cited : (106)

References (94)
  • 1
    • 0036597371 scopus 로고    scopus 로고
    • CD4+ CD25+ suppressorT cells: More questions than answers
    • Shevach EM. CD4+ CD25+ suppressorT cells: more questions than answers. Nat Rev Immunol. 2002;2:389-400.
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 2
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol. 2004;22:531-562.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 3
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol. 1995; 155:1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 4
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
    • Asano M. Toda M, Sakaguchi N, Sakaguchi S. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med. 1996;184:387-396.
    • (1996) J Exp Med , vol.184 , pp. 387-396
    • Asano, M.1    Toda, M.2    Sakaguchi, N.3    Sakaguchi, S.4
  • 5
    • 0033136302 scopus 로고    scopus 로고
    • Thymus and autoimmunity: Production of CD25 + CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • Itoh M. Takahashi T, Sakaguchi N, et al. Thymus and autoimmunity: production of CD25 + CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol. 1999;162:5317-5326.
    • (1999) J Immunol , vol.162 , pp. 5317-5326
    • Itoh, M.1    Takahashi, T.2    Sakaguchi, N.3
  • 6
    • 14944346738 scopus 로고    scopus 로고
    • Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD
    • Ermann J, Hoffmann P, Edinger M, et al. Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD. Blood. 2005;105:2220-2226.
    • (2005) Blood , vol.105 , pp. 2220-2226
    • Ermann, J.1    Hoffmann, P.2    Edinger, M.3
  • 7
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by GD25(+)GD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • Takahashi T Tagami T Yamazaki S, et al. Immunologic self-tolerance maintained by GD25(+)GD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med. 2000;192:303-310.
    • (2000) J Exp Med , vol.192 , pp. 303-310
    • Takahashi, T.1    Tagami, T.2    Yamazaki, S.3
  • 8
    • 0033682056 scopus 로고    scopus 로고
    • B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
    • Salomon B, Lenschow DJ, Rhee L, et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity. 2000;12:431-440.
    • (2000) Immunity , vol.12 , pp. 431-440
    • Salomon, B.1    Lenschow, D.J.2    Rhee, L.3
  • 9
    • 0034679567 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of GD25(+)CD4(+) regulatory cells that control intestinal inflammation
    • Read S, Malmstrom V, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of GD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med. 2000;192:295-302.
    • (2000) J Exp Med , vol.192 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 10
    • 0036170938 scopus 로고    scopus 로고
    • Stimulation of CD25(+)CD4(+) regulatoryT cells through GITR breaks immunological self-tolerance
    • Shimizu J, Yamazaki S. Takahashi T, Ishida Y, Sakaguchi S. Stimulation of CD25(+)CD4(+) regulatoryT cells through GITR breaks immunological self-tolerance. Nat Immunol. 2002;3:135-142.
    • (2002) Nat Immunol , vol.3 , pp. 135-142
    • Shimizu, J.1    Yamazaki, S.2    Takahashi, T.3    Ishida, Y.4    Sakaguchi, S.5
  • 11
    • 0036467347 scopus 로고    scopus 로고
    • Regulatory T cells overexpress a subset of Th2 gene transcripts
    • Zelenika D. Adams E. Humm S, et al. Regulatory T cells overexpress a subset of Th2 gene transcripts. J Immunol. 2002;168:1069-1079.
    • (2002) J Immunol , vol.168 , pp. 1069-1079
    • Zelenika, D.1    Adams, E.2    Humm, S.3
  • 12
    • 0036195161 scopus 로고    scopus 로고
    • GD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • McHugh RS, Whitters MJ, Piccirillo CA, et al. GD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity. 2002;16:311-323.
    • (2002) Immunity , vol.16 , pp. 311-323
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillo, C.A.3
  • 13
    • 0036791004 scopus 로고    scopus 로고
    • Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25 regulatory T cells
    • Lehmann J, Huehn J, de la Rosa M, et al. Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25" regulatory T cells. Proc Natl Acad Sci U S A. 2002;99:13031-13036.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13031-13036
    • Lehmann, J.1    Huehn, J.2    de la Rosa, M.3
  • 14
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S. Nomura T. Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003;299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 15
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol. 2003;4:330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 16
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol. 2003;4:337-342.
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 17
    • 0031821875 scopus 로고    scopus 로고
    • GD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • Thornton AM, Shevach EM. GD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med. 1998;188:287-296.
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 18
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi T Kuniyasu Y Toda M, et al. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol. 1998;10: 1969-1980.
    • (1998) Int Immunol , vol.10 , pp. 1969-1980
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3
  • 19
    • 0031739410 scopus 로고    scopus 로고
    • CD38+ CD45RB(low) CD4+ T cells: A population of T cells with immune regulatory activities in vitro
    • Read S, Mauze S, Asseman C, et al. CD38+ CD45RB(low) CD4+ T cells: a population of T cells with immune regulatory activities in vitro. Eur J Immunol. 1998;28:3435-3447.
    • (1998) Eur J Immunol , vol.28 , pp. 3435-3447
    • Read, S.1    Mauze, S.2    Asseman, C.3
  • 20
    • 0035421654 scopus 로고    scopus 로고
    • Cutting edge: Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
    • Piccirillo CA, Shevach EM. Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J Immunol. 2001;167:1137-1140.
    • (2001) J Immunol , vol.167 , pp. 1137-1140
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 21
    • 0035887614 scopus 로고    scopus 로고
    • Ermann J, Szanya V. Ford GS, et al. CD4(+)CD25(+) T cells facilitate the induction of Tcellanergy. J Immunol. 2001; 167:4271-4275.
    • Ermann J, Szanya V. Ford GS, et al. CD4(+)CD25(+) T cells facilitate the induction of Tcellanergy. J Immunol. 2001; 167:4271-4275.
  • 22
    • 36248976097 scopus 로고    scopus 로고
    • CD4(+)CD25(+)Foxp3(+) regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4(+) T cells
    • Pandiyan P, Zheng L Ishihara S, Reed J, Lenardo MJ. CD4(+)CD25(+)Foxp3(+) regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4(+) T cells. Nat Immunol. 2007;8:1353-1362.
    • (2007) Nat Immunol , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 23
    • 0034716925 scopus 로고    scopus 로고
    • T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell. 2000;101: 455-458.
    • (2000) Cell , vol.101 , pp. 455-458
    • Regulatory, S.S.1
  • 24
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy KJ. Powrie F. Regulatory T cells in the control of immune pathology. Nat Immunol. 2001;2: 816-822.
    • (2001) Nat Immunol , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 25
    • 0035181730 scopus 로고    scopus 로고
    • Regulatory T cells: The physiology of autoreactivity in dominant tolerance and "quality control" of immune responses
    • Coutinho A, Hori S, Carvalho T Caramalho I, Demengeot J. Regulatory T cells: the physiology of autoreactivity in dominant tolerance and "quality control" of immune responses. Immunol Rev. 2001;182:89-98.
    • (2001) Immunol Rev , vol.182 , pp. 89-98
    • Coutinho, A.1    Hori, S.2    Carvalho, T.3    Caramalho, I.4    Demengeot, J.5
  • 26
    • 0029956024 scopus 로고    scopus 로고
    • Powrie F, Carlino J, Leach MW. Mauze S, Coff man RL. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low)CD4+T cells. J Exp Med. 1996; 183:2669-2674.
    • Powrie F, Carlino J, Leach MW. Mauze S, Coff man RL. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low)CD4+T cells. J Exp Med. 1996; 183:2669-2674.
  • 27
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med. 1999;190:995-1004.
    • (1999) J Exp Med , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 28
    • 0034176747 scopus 로고    scopus 로고
    • Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment
    • Annacker O, Burlen-Defranoux O, Pimenta-Araujo R, Cumano A, Bandeira A. Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment. J Immunol. 2000;164:3573-3580.
    • (2000) J Immunol , vol.164 , pp. 3573-3580
    • Annacker, O.1    Burlen-Defranoux, O.2    Pimenta-Araujo, R.3    Cumano, A.4    Bandeira, A.5
  • 29
    • 0346888498 scopus 로고    scopus 로고
    • Control of autoimmunity by naturally arising regulatory CD4+ T cells
    • Hori S, Takahashi T, Sakaguchi S. Control of autoimmunity by naturally arising regulatory CD4+ T cells. Adv Immunol. 2003;81:331-371.
    • (2003) Adv Immunol , vol.81 , pp. 331-371
    • Hori, S.1    Takahashi, T.2    Sakaguchi, S.3
  • 30
    • 0035801335 scopus 로고    scopus 로고
    • Cell contactdependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • Nakamura K, Kitani A, Strober W. Cell contactdependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med. 2001;194:629-644.
    • (2001) J Exp Med , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 31
    • 0037243827 scopus 로고    scopus 로고
    • CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
    • Maloy KJ, Salaun L, Cahill R, et al. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J Exp Med. 2003;197:111-119.
    • (2003) J Exp Med , vol.197 , pp. 111-119
    • Maloy, K.J.1    Salaun, L.2    Cahill, R.3
  • 32
    • 1342324588 scopus 로고    scopus 로고
    • The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells
    • Hesse M, Piccirillo CA, Belkaid Y, et al. The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells. J Immunol. 2004;172:3157-3166.
    • (2004) J Immunol , vol.172 , pp. 3157-3166
    • Hesse, M.1    Piccirillo, C.A.2    Belkaid, Y.3
  • 33
    • 0035181616 scopus 로고    scopus 로고
    • Natural CD4+ CD25+ regulatory T cells: Their role in the control of superantigen responses
    • Papiernik M. Natural CD4+ CD25+ regulatory T cells: their role in the control of superantigen responses. Immunol Rev. 2001;182:180-189.
    • (2001) Immunol Rev , vol.182 , pp. 180-189
    • Papiernik, M.1
  • 34
    • 18844371714 scopus 로고    scopus 로고
    • Regulation of CD4+CD25+ regulatoryT cell activity: It takes (IL-)two to tango
    • Scheffold A, Huhn J, Hofer T. Regulation of CD4+CD25+ regulatoryT cell activity: it takes (IL-)two to tango. Eur J Immunol. 2005;35:1336-1341.
    • (2005) Eur J Immunol , vol.35 , pp. 1336-1341
    • Scheffold, A.1    Huhn, J.2    Hofer, T.3
  • 36
    • 15444374646 scopus 로고    scopus 로고
    • Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • Setoguchi R, Hori S, Takahashi T, Sakaguchi S. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med. 2005;201:723-735.
    • (2005) J Exp Med , vol.201 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3    Sakaguchi, S.4
  • 37
    • 15544384475 scopus 로고    scopus 로고
    • Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period
    • BayerAL, Yu A, Adeegbe D, Malek TR. Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period. J Exp Med. 2005;201:769-777.
    • (2005) J Exp Med , vol.201 , pp. 769-777
    • Bayer, A.L.1    Yu, A.2    Adeegbe, D.3    Malek, T.R.4
  • 38
    • 30744458573 scopus 로고    scopus 로고
    • Lymphopenia and interleukin-2 therapy alter homeostasis of CD4(+)CD25(+) regulatory T cells
    • Zhang H, Chua KS, Guimond M, et al. Lymphopenia and interleukin-2 therapy alter homeostasis of CD4(+)CD25(+) regulatory T cells. Nat Med. 2005;11:1238-1243.
    • (2005) Nat Med , vol.11 , pp. 1238-1243
    • Zhang, H.1    Chua, K.S.2    Guimond, M.3
  • 39
    • 2442637772 scopus 로고    scopus 로고
    • Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function
    • Thornton AM, Donovan EE, Piccirillo CA, Shevach EM. Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function. J Immunol. 2004; 172: 6519-6523.
    • (2004) J Immunol , vol.172 , pp. 6519-6523
    • Thornton, A.M.1    Donovan, E.E.2    Piccirillo, C.A.3    Shevach, E.M.4
  • 40
    • 1642390941 scopus 로고    scopus 로고
    • Activation requirements for the induction of CD4+CD25+ Tcell suppressor function
    • Thornton AM, Piccirillo CA, Shevach EM. Activation requirements for the induction of CD4+CD25+ Tcell suppressor function. Eur J Immunol. 2004;34:366-376.
    • (2004) Eur J Immunol , vol.34 , pp. 366-376
    • Thornton, A.M.1    Piccirillo, C.A.2    Shevach, E.M.3
  • 41
    • 4644369302 scopus 로고    scopus 로고
    • Interleukin-2 is essential for CD4+CD25+ regulatory Tcell function
    • de la Rosa M, Rutz S, Dorninger H, Scheffold A. Interleukin-2 is essential for CD4+CD25+ regulatory Tcell function. Eur J Immunol. 2004;34: 2480-2488.
    • (2004) Eur J Immunol , vol.34 , pp. 2480-2488
    • de la Rosa, M.1    Rutz, S.2    Dorninger, H.3    Scheffold, A.4
  • 42
    • 14944386649 scopus 로고    scopus 로고
    • CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production
    • Barthlott T, Moncrieffe H, Veldhoen M, et al. CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production. Int Immunol. 2005:17:279-288.
    • (2005) Int Immunol , vol.17 , pp. 279-288
    • Barthlott, T.1    Moncrieffe, H.2    Veldhoen, M.3
  • 43
    • 34447572680 scopus 로고    scopus 로고
    • IL-2Rbeta links IL-2R signaling with Foxp3 expression
    • Soper DM, Kasprowicz DJ, Ziegler SF. IL-2Rbeta links IL-2R signaling with Foxp3 expression. Eur J Immunol. 2007;37:1817-1826.
    • (2007) Eur J Immunol , vol.37 , pp. 1817-1826
    • Soper, D.M.1    Kasprowicz, D.J.2    Ziegler, S.F.3
  • 44
    • 33845935950 scopus 로고    scopus 로고
    • IL-2 receptor beta-dependent STATS activation is required tor the development of Foxp3+ regulatory T cells
    • Burchill MA, Yang J, Vogtenhuber C, Blazar BR, Farrar MA. IL-2 receptor beta-dependent STATS activation is required tor the development of Foxp3+ regulatory T cells. J Immunol. 2007;178: 280-290.
    • (2007) J Immunol , vol.178 , pp. 280-290
    • Burchill, M.A.1    Yang, J.2    Vogtenhuber, C.3    Blazar, B.R.4    Farrar, M.A.5
  • 45
    • 0028783963 scopus 로고
    • Generalized autoimmune disease in interleukin-2-deticient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells
    • Sadlack B, Lohler J, Schorle H, et al. Generalized autoimmune disease in interleukin-2-deticient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells. Eur J Immunol. 1995:25:3053-3059.
    • (1995) Eur J Immunol , vol.25 , pp. 3053-3059
    • Sadlack, B.1    Lohler, J.2    Schorle, H.3
  • 46
    • 0029028363 scopus 로고
    • Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
    • Suzuki H, Kundig TM, Furlonger C, et al. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta. Science. 1995;268:1472-1476.
    • (1995) Science , vol.268 , pp. 1472-1476
    • Suzuki, H.1    Kundig, T.M.2    Furlonger, C.3
  • 47
    • 0028784289 scopus 로고
    • Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
    • Willerford DM, Chen J, Ferry JA, et al. Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity. 1995;3:521-530.
    • (1995) Immunity , vol.3 , pp. 521-530
    • Willerford, D.M.1    Chen, J.2    Ferry, J.A.3
  • 48
    • 0036839102 scopus 로고    scopus 로고
    • Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
    • Almeida AR, Legrand N, Papiernik M, Freitas AA. Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers. J Immunol. 2002;169:4850-4860.
    • (2002) J Immunol , vol.169 , pp. 4850-4860
    • Almeida, A.R.1    Legrand, N.2    Papiernik, M.3    Freitas, A.A.4
  • 49
    • 0036669298 scopus 로고    scopus 로고
    • CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice: Implications tor the nonredundant function of IL-2
    • Malek TR, Yu A, Vincek V, Scibelli P, Kong L. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice: implications tor the nonredundant function of IL-2. Immunity. 2002; 17:167-178.
    • (2002) Immunity , vol.17 , pp. 167-178
    • Malek, T.R.1    Yu, A.2    Vincek, V.3    Scibelli, P.4    Kong, L.5
  • 50
    • 0031815678 scopus 로고    scopus 로고
    • The role of interleukin-7 in early T-cell development
    • Offner F, Plum J. The role of interleukin-7 in early T-cell development. Leuk Lymphoma. 1998;30: 87-99.
    • (1998) Leuk Lymphoma , vol.30 , pp. 87-99
    • Offner, F.1    Plum, J.2
  • 51
    • 1442276985 scopus 로고    scopus 로고
    • Cytokines in the thymus: Production and biological effects
    • Yarilin AA, Belyakov IM. Cytokines in the thymus: production and biological effects. Curr Med Chem. 2004;11:447-464.
    • (2004) Curr Med Chem , vol.11 , pp. 447-464
    • Yarilin, A.A.1    Belyakov, I.M.2
  • 52
    • 0036771728 scopus 로고    scopus 로고
    • The role of cytokines in lymphocyte homeostasis
    • Khaled AR, Durum SK. The role of cytokines in lymphocyte homeostasis. Biotechniques. 2002; (suppl):40-45.
    • (2002) Biotechniques , Issue.SUPPL. , pp. 40-45
    • Khaled, A.R.1    Durum, S.K.2
  • 53
    • 0027751556 scopus 로고
    • Interleukin-2 receptorgamma chain: Afunctional component of the interleukin-7 receptor
    • Noguchi M. Nakamura Y. Russell SM, et al. Interleukin-2 receptorgamma chain: afunctional component of the interleukin-7 receptor. Science. 1993:262:1877-1880.
    • (1993) Science , vol.262 , pp. 1877-1880
    • Noguchi, M.1    Nakamura, Y.2    Russell, S.M.3
  • 54
    • 0027731604 scopus 로고
    • Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4
    • Kondo M, Takeshita T, Ishii N, et al. Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4. Science. 1993; 262:1874-1877.
    • (1993) Science , vol.262 , pp. 1874-1877
    • Kondo, M.1    Takeshita, T.2    Ishii, N.3
  • 55
    • 0034232353 scopus 로고    scopus 로고
    • Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin
    • Pandey A, Ozaki K, Baumann H, et al. Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin. Nat Immunol. 2000;1: 59-64.
    • (2000) Nat Immunol , vol.1 , pp. 59-64
    • Pandey, A.1    Ozaki, K.2    Baumann, H.3
  • 56
    • 0034605037 scopus 로고    scopus 로고
    • Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of afunctional heteromeric complex requires interleukin 7 receptor
    • Park LS, Martin U, Garka K, et al. Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: formation of afunctional heteromeric complex requires interleukin 7 receptor. J Exp Med. 2000;192:659-670.
    • (2000) J Exp Med , vol.192 , pp. 659-670
    • Park, L.S.1    Martin, U.2    Garka, K.3
  • 57
    • 0035902513 scopus 로고    scopus 로고
    • IL-7 is critical for homeostatic proliferation and survival of naive T cells
    • Tan JT, Dudl E, LeRoy E, et al. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci U S A. 2001;98:8732-8737.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 8732-8737
    • Tan, J.T.1    Dudl, E.2    LeRoy, E.3
  • 58
    • 0347281680 scopus 로고    scopus 로고
    • Interleukin 7 regulates the survival and generation of memory CD4 cells
    • Kondrack RM, Harbertson J, Tan JT, et al. Interleukin 7 regulates the survival and generation of memory CD4 cells. J Exp Med. 2003;198:1797-1806.
    • (2003) J Exp Med , vol.198 , pp. 1797-1806
    • Kondrack, R.M.1    Harbertson, J.2    Tan, J.T.3
  • 59
    • 0036687184 scopus 로고    scopus 로고
    • Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines
    • Bacchetta R, Sartirana C, Levings MK, et al. Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines. Eur J Immunol. 2002:32:2237-2245.
    • (2002) Eur J Immunol , vol.32 , pp. 2237-2245
    • Bacchetta, R.1    Sartirana, C.2    Levings, M.K.3
  • 60
    • 33749320682 scopus 로고    scopus 로고
    • Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7
    • de Latour RP, Dujardin HC, Mishellany F, et al. Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7. Blood. 2006;108:2300-2306.
    • (2006) Blood , vol.108 , pp. 2300-2306
    • de Latour, R.P.1    Dujardin, H.C.2    Mishellany, F.3
  • 61
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
    • Liu W, Putnam AL, Xu-Yu Z, et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med. 2006;203:1701-1711.
    • (2006) J Exp Med , vol.203 , pp. 1701-1711
    • Liu, W.1    Putnam, A.L.2    Xu-Yu, Z.3
  • 62
  • 63
    • 3242757478 scopus 로고    scopus 로고
    • A role for thymic stromal lymphopoietin in CD4(+) T cell development
    • Al-Shami A, Spolski R, Kelly J, et al. A role for thymic stromal lymphopoietin in CD4(+) T cell development. J Exp Med. 2004;200:159-168.
    • (2004) J Exp Med , vol.200 , pp. 159-168
    • Al-Shami, A.1    Spolski, R.2    Kelly, J.3
  • 64
    • 1642321960 scopus 로고    scopus 로고
    • Thymocytes between the beta-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation
    • Van De Wiele CJ, Marino JH, Murray BW, et al. Thymocytes between the beta-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation. J Immunol. 2004;172:4235-4244.
    • (2004) J Immunol , vol.172 , pp. 4235-4244
    • Van De Wiele, C.J.1    Marino, J.H.2    Murray, B.W.3
  • 65
    • 1542285926 scopus 로고    scopus 로고
    • One-step real-time duplex reverse transcription PCRs simultaneously quantify analyte and housekeeping gene rnRNAs
    • Wang C, Gao D, Vaglenov A, Kaltenboeck B. One-step real-time duplex reverse transcription PCRs simultaneously quantify analyte and housekeeping gene rnRNAs. Biotechniques. 2004;36:508-509.
    • (2004) Biotechniques , vol.36 , pp. 508-509
    • Wang, C.1    Gao, D.2    Vaglenov, A.3    Kaltenboeck, B.4
  • 66
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 67
    • 3042599891 scopus 로고    scopus 로고
    • Automated process of Q-PCR/gene expression
    • Cherry JM, Stewart C, Frankenberger C, et al. Automated process of Q-PCR/gene expression. JALA. 2004;9:128-134.
    • (2004) JALA , vol.9 , pp. 128-134
    • Cherry, J.M.1    Stewart, C.2    Frankenberger, C.3
  • 68
    • 0037374497 scopus 로고    scopus 로고
    • Characterization of an interleukin-7-dependent thymic cell line derived from a p53(-/-) mouse
    • Kim K, Khaled AR, Reynolds D, et al. Characterization of an interleukin-7-dependent thymic cell line derived from a p53(-/-) mouse. J Immunol Methods. 2003;274:177-184.
    • (2003) J Immunol Methods , vol.274 , pp. 177-184
    • Kim, K.1    Khaled, A.R.2    Reynolds, D.3
  • 69
    • 85119814265 scopus 로고    scopus 로고
    • Nolan GP, Shatzman AR. Expression vectors and delivery systems. Gurr Opin Biotechnol. 1998;9: 447-450.
    • Nolan GP, Shatzman AR. Expression vectors and delivery systems. Gurr Opin Biotechnol. 1998;9: 447-450.
  • 70
    • 0037109077 scopus 로고    scopus 로고
    • IL-2 negatively regulates IL-7 receptor alpha chain expression in activated T lymphocytes
    • Xue HH, Kovanen PE, Pise-Masison CA, et al. IL-2 negatively regulates IL-7 receptor alpha chain expression in activated T lymphocytes. Proc Natl Acad Sci U S A. 2002;99:13759-13764.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13759-13764
    • Xue, H.H.1    Kovanen, P.E.2    Pise-Masison, C.A.3
  • 71
    • 4143085811 scopus 로고    scopus 로고
    • Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: A novel mechanism for maximizing IL-7-dependent T cell survival
    • Park JH, Yu O, Erman B, et al. Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. Immunity. 2004;21:289-302.
    • (2004) Immunity , vol.21 , pp. 289-302
    • Park, J.H.1    Yu, O.2    Erman, B.3
  • 72
    • 33846632842 scopus 로고    scopus 로고
    • Interleukin-7 receptor expression: Intelligent design
    • Mazzucchelli R, Durum SK. Interleukin-7 receptor expression: intelligent design. Nat Rev Immunol. 2007;7:144-154.
    • (2007) Nat Rev Immunol , vol.7 , pp. 144-154
    • Mazzucchelli, R.1    Durum, S.K.2
  • 73
  • 74
    • 23944459169 scopus 로고    scopus 로고
    • Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin
    • Yoo J, Omori M, Gyarmati D, et al. Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J Exp Med. 2005;202:541-549.
    • (2005) J Exp Med , vol.202 , pp. 541-549
    • Yoo, J.1    Omori, M.2    Gyarmati, D.3
  • 75
    • 25844515028 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
    • Zhou B, Comeau MR, De Smedt T, et al. Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice. Nat Immunol. 2005; 6:1047-1053.
    • (2005) Nat Immunol , vol.6 , pp. 1047-1053
    • Zhou, B.1    Comeau, M.R.2    De Smedt, T.3
  • 76
    • 20444365526 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity
    • Ying S, O'Connor B, Ratoff J, et al. Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J Immunol. 2005;174:8183-8190.
    • (2005) J Immunol , vol.174 , pp. 8183-8190
    • Ying, S.1    O'Connor, B.2    Ratoff, J.3
  • 77
    • 33745207614 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin in normal and pathogenic T cell development and function
    • Ziegler SF, Liu YJ. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nat Immunol. 2006;7:709-714.
    • (2006) Nat Immunol , vol.7 , pp. 709-714
    • Ziegler, S.F.1    Liu, Y.J.2
  • 78
    • 24144480562 scopus 로고    scopus 로고
    • Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus
    • Watanabe N, Wang YH, Lee HK, et al. Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus. Nature. 2005;436:1181-1185.
    • (2005) Nature , vol.436 , pp. 1181-1185
    • Watanabe, N.1    Wang, Y.H.2    Lee, H.K.3
  • 79
    • 34249792099 scopus 로고    scopus 로고
    • Cutting edge: Direct action of thymic stromal lymphopoietin on activated human CD4+ T cells
    • Rochman I, Watanabe N, Arima K, Liu YJ, Leonard WJ. Cutting edge: direct action of thymic stromal lymphopoietin on activated human CD4+ T cells. J Immunol. 2007;178:6720-6724.
    • (2007) J Immunol , vol.178 , pp. 6720-6724
    • Rochman, I.1    Watanabe, N.2    Arima, K.3    Liu, Y.J.4    Leonard, W.J.5
  • 80
    • 7144259082 scopus 로고    scopus 로고
    • Regulatory CD4 T cells: Expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
    • Papiernik M, de Moraes ML. Pontoux C, Vasseur F, Penit C. Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency. Int Immunol. 1998;10:371-378.
    • (1998) Int Immunol , vol.10 , pp. 371-378
    • Papiernik, M.1    de Moraes, M.L.2    Pontoux, C.3    Vasseur, F.4    Penit, C.5
  • 81
    • 0348047537 scopus 로고    scopus 로고
    • The main function of IL-2 is to promote the development of T regulatory cells
    • Malek TR. The main function of IL-2 is to promote the development of T regulatory cells. J Leukoc Biol. 2003;74:961-965.
    • (2003) J Leukoc Biol , vol.74 , pp. 961-965
    • Malek, T.R.1
  • 82
    • 33749524594 scopus 로고    scopus 로고
    • Selective availability of IL-2 is a major determinant controlling the production of CD4+CD25+Foxp3+T regulatory cells
    • Yu A, Malek TR. Selective availability of IL-2 is a major determinant controlling the production of CD4+CD25+Foxp3+T regulatory cells. J Immunol. 2006;177:5115-5121.
    • (2006) J Immunol , vol.177 , pp. 5115-5121
    • Yu, A.1    Malek, T.R.2
  • 83
    • 0031587875 scopus 로고    scopus 로고
    • Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/-mice
    • Maraskovsky E, O'Reilly LA, Teepe M, et al. Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/-mice. Cell. 1997;89:1011-1019.
    • (1997) Cell , vol.89 , pp. 1011-1019
    • Maraskovsky, E.1    O'Reilly, L.A.2    Teepe, M.3
  • 84
    • 0031587826 scopus 로고    scopus 로고
    • Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    • Akashi K, Kondo M, von Freeden-Jeffry U, Murray R, Weissman IL. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell. 1997;89:1033-1041.
    • (1997) Cell , vol.89 , pp. 1033-1041
    • Akashi, K.1    Kondo, M.2    von Freeden-Jeffry, U.3    Murray, R.4    Weissman, I.L.5
  • 85
    • 0036849781 scopus 로고    scopus 로고
    • Bax deficiency partially corrects interleukin-7 receptor alpha deficiency
    • Khaled AR, Li WQ, Huang J, et al. Bax deficiency partially corrects interleukin-7 receptor alpha deficiency. Immunity. 2002;17:561-573.
    • (2002) Immunity , vol.17 , pp. 561-573
    • Khaled, A.R.1    Li, W.Q.2    Huang, J.3
  • 86
    • 0033696599 scopus 로고    scopus 로고
    • Coreceptor reversal in the thymus: Signaled CD4+8+ thymocytes initially terminate CDS transcription even when differentiating into CDS 4-T cells
    • Brugnera E, Bhandoola A, Cibotti R, et al. Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CDS transcription even when differentiating into CDS 4-T cells. Immunity. 2000;13:59-71.
    • (2000) Immunity , vol.13 , pp. 59-71
    • Brugnera, E.1    Bhandoola, A.2    Cibotti, R.3
  • 87
    • 0032441260 scopus 로고    scopus 로고
    • Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: Role of receptor-associated chains and locus accessibility
    • Durum SK, Candeias S, Nakajima H, et al. Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility. J Exp Med. 1998; 188:2233-2241.
    • (1998) J Exp Med , vol.188 , pp. 2233-2241
    • Durum, S.K.1    Candeias, S.2    Nakajima, H.3
  • 88
    • 22344438505 scopus 로고    scopus 로고
    • Cytokine-driven cell cycling is mediated through Cdc25A
    • Khaled AR, Bulavin DV, Kittipatarin C, et al. Cytokine-driven cell cycling is mediated through Cdc25A. J Cell Biol. 2005;169:755-763.
    • (2005) J Cell Biol , vol.169 , pp. 755-763
    • Khaled, A.R.1    Bulavin, D.V.2    Kittipatarin, C.3
  • 89
    • 33645064841 scopus 로고    scopus 로고
    • IL-7 promotes Tcell proliferation through destabilization of p27Kip1
    • Li WQ, Jiang Q, Aleem E, et al. IL-7 promotes Tcell proliferation through destabilization of p27Kip1. J Exp Med. 2006;203:573-582.
    • (2006) J Exp Med , vol.203 , pp. 573-582
    • Li, W.Q.1    Jiang, Q.2    Aleem, E.3
  • 90
    • 8644219870 scopus 로고    scopus 로고
    • Loss of Bim increases Tcell production and function in interleukin 7 receptor-deficient mice
    • Pellegrini M, Bouillet P, Robati M, et al. Loss of Bim increases Tcell production and function in interleukin 7 receptor-deficient mice. J Exp Med. 2004;200:1189-1195.
    • (2004) J Exp Med , vol.200 , pp. 1189-1195
    • Pellegrini, M.1    Bouillet, P.2    Robati, M.3
  • 91
    • 33746348281 scopus 로고    scopus 로고
    • The roles for cytokines in the generation and maintenance of regulatory T cells
    • Wan YY Flavell RA. The roles for cytokines in the generation and maintenance of regulatory T cells. Immunol Rev. 2006;212:114-130.
    • (2006) Immunol Rev , vol.212 , pp. 114-130
    • Wan, Y.Y.1    Flavell, R.A.2
  • 92
    • 0032526586 scopus 로고    scopus 로고
    • The trophic action of IL-7 on pro-T cells: Inhibition of apoptosis of pro-T1.-T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways
    • Kim K, Lee CK, Sayers TJ, Muegge K, Durum SK. The trophic action of IL-7 on pro-T cells: inhibition of apoptosis of pro-T1.-T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways. J Immunol. 1998;160:5735-5741.
    • (1998) J Immunol , vol.160 , pp. 5735-5741
    • Kim, K.1    Lee, C.K.2    Sayers, T.J.3    Muegge, K.4    Durum, S.K.5
  • 93
    • 0027988545 scopus 로고
    • Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
    • Peschon JJ, Morrissey PJ, Grabstein KH, et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med. 1994;180:1955-1960.
    • (1994) J Exp Med , vol.180 , pp. 1955-1960
    • Peschon, J.J.1    Morrissey, P.J.2    Grabstein, K.H.3
  • 94
    • 0028929565 scopus 로고
    • Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
    • von Freeden-Jeffry U. Vieira P. Lucian LA, et al. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med. 1995;181:1519-1526.
    • (1995) J Exp Med , vol.181 , pp. 1519-1526
    • von Freeden-Jeffry, U.1    Vieira, P.2    Lucian, L.A.3


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