-
1
-
-
0027209141
-
Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody
-
Grabstein, K. H. et al. Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody. J. Exp. Med. 178, 257-264 (1993).
-
(1993)
J. Exp. Med
, vol.178
, pp. 257-264
-
-
Grabstein, K.H.1
-
2
-
-
0027443753
-
Expression and function of the interleukin 7 receptor in murine lymphocytes
-
Sudo, T. et al. Expression and function of the interleukin 7 receptor in murine lymphocytes. Proc. Natl Acad. Sci. USA 90, 9125-9129 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 9125-9129
-
-
Sudo, T.1
-
3
-
-
0028955101
-
The effect of in vivo IL-7 deprivation on T cell maturation
-
Bhatia, S. K., Tygrett, L. T., Grabstein, K. H. & Waldschmidt, T. J. The effect of in vivo IL-7 deprivation on T cell maturation. J. Exp. Med. 181, 1399-1409 (1995).
-
(1995)
J. Exp. Med
, vol.181
, pp. 1399-1409
-
-
Bhatia, S.K.1
Tygrett, L.T.2
Grabstein, K.H.3
Waldschmidt, T.J.4
-
4
-
-
0028929565
-
-
von Freeden-Jeffry, U. et al. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 181, 1519-1526 (1995). Knockout of the Il7 gene recapitulates the marked lymphopaenia seen in Il7r-knockout mice.
-
(1995)
J. Exp. Med
, vol.181
, pp. 1519-1526
-
-
von Freeden-Jeffry, U.1
-
5
-
-
0027988545
-
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
-
Peschon, J. J. et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J. Exp. Med. 180, 1955-1960 (1994). Knockout of Il7r results in severe thymic deficiency and lymphopaenia in mice.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1955-1960
-
-
Peschon, J.J.1
-
6
-
-
0029957040
-
Interleukin 7 receptor-deficient mice lack γδ T cells
-
Maki, K. et al. Interleukin 7 receptor-deficient mice lack γδ T cells. Proc. Natl Acad. Sci. USA 93, 7172-7177 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 7172-7177
-
-
Maki, K.1
-
7
-
-
0028986904
-
Induction of TCR-γδ expression on triple-negative (CD3-4-8-) human thymocytes. Comparative analysis of the effects of IL-4 and IL-7
-
He, W., Zhang, Y., Deng, Y. & Kabelitz, D. Induction of TCR-γδ expression on triple-negative (CD3-4-8-) human thymocytes. Comparative analysis of the effects of IL-4 and IL-7. J. Immunol. 154, 3726-3731 (1995).
-
(1995)
J. Immunol
, vol.154
, pp. 3726-3731
-
-
He, W.1
Zhang, Y.2
Deng, Y.3
Kabelitz, D.4
-
8
-
-
0029859982
-
Interleukin-7 is a critical growth factor in early human T-cell development
-
Plum, J., De, S. M., Leclercq, G., Verhasselt, B. & Vandekerckhove, B. Interleukin-7 is a critical growth factor in early human T-cell development. Blood 88, 4239-4245 (1996).
-
(1996)
Blood
, vol.88
, pp. 4239-4245
-
-
Plum, J.1
De, S.M.2
Leclercq, G.3
Verhasselt, B.4
Vandekerckhove, B.5
-
9
-
-
0030199773
-
Development of CD4 and CD8 single positive T cells in human thymus organ culture: IL-7 promotes human T cell production by supporting immature T cells
-
Yeoman, H., Clark, D. R. & DeLuca, D. Development of CD4 and CD8 single positive T cells in human thymus organ culture: IL-7 promotes human T cell production by supporting immature T cells. Dev. Comp. Immunol. 20, 241-263 (1996).
-
(1996)
Dev. Comp. Immunol
, vol.20
, pp. 241-263
-
-
Yeoman, H.1
Clark, D.R.2
DeLuca, D.3
-
10
-
-
0034332403
-
Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nature Immunol
-
426-432
-
Schluns, K. S., Kieper, W. C., Jameson, S. C. & Lefrancois, L. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nature Immunol. 1, 426-432 (2000). Shows that IL-7 is required for the survival of mature peripheral T cells and notes that antigen stimulation downregulates IL-7Rα expression.
-
(2000)
Shows that IL-7 is required for the survival of mature peripheral T cells and notes that antigen stimulation downregulates IL-7Rα expression
, vol.1
-
-
Schluns, K.S.1
Kieper, W.C.2
Jameson, S.C.3
Lefrancois, L.4
-
11
-
-
0347281680
-
Interleukin 7 regulates the survival and generation of memory CD4 cells
-
Kondrack, R. M. et al. Interleukin 7 regulates the survival and generation of memory CD4 cells. J. Exp. Med. 198, 1797-1806 (2003).
-
(2003)
J. Exp. Med
, vol.198
, pp. 1797-1806
-
-
Kondrack, R.M.1
-
12
-
-
27744447066
-
Molecular defects in T- and B-cell primary immunodeficiency diseases
-
Nature Rev. Immunol, IL- pathway in humans
-
Cunningham-Rundles, C. & Ponda, P. P. Molecular defects in T- and B-cell primary immunodeficiency diseases. Nature Rev. Immunol. 5, 880-892 (2005). Reviews the requirements for the IL-7 pathway in humans.
-
(2005)
Reviews the requirements for the
, vol.5
, Issue.11
, pp. 880-892
-
-
Cunningham-Rundles, C.1
Ponda, P.P.2
-
13
-
-
0030018826
-
+ T cells, but not natural killer cells
-
+ T cells, but not natural killer cells. J. Exp. Med. 184, 289-293 (1996).
-
(1996)
J. Exp. Med
, vol.184
, pp. 289-293
-
-
He, Y.W.1
Malek, T.R.2
-
14
-
-
0030791028
-
Distinct roles for signals relayed through the common cytokine receptor γ chain and interleukin 7 receptor α chain in natural T cell development
-
Boesteanu, A. et al. Distinct roles for signals relayed through the common cytokine receptor γ chain and interleukin 7 receptor α chain in natural T cell development. J. Exp. Med. 186, 331-336 (1997).
-
(1997)
J. Exp. Med
, vol.186
, pp. 331-336
-
-
Boesteanu, A.1
-
15
-
-
0036831818
-
Lymphocide: Cytokines and the control of lymphoid homeostasis
-
Khaled, A. R. & Durum, S. K. Lymphocide: cytokines and the control of lymphoid homeostasis. Nature Rev. Immunol. 2, 817-830 (2002).
-
(2002)
Nature Rev. Immunol
, vol.2
, pp. 817-830
-
-
Khaled, A.R.1
Durum, S.K.2
-
16
-
-
0032441260
-
Interleukin 7 receptor control of T cell receptor γ gene rearrangement: Role of receptor-associated chains and locus accessibility
-
Durum, S. K. et al. Interleukin 7 receptor control of T cell receptor γ gene rearrangement: role of receptor-associated chains and locus accessibility. J. Exp. Med. 188, 2233-2241 (1998).
-
(1998)
J. Exp. Med
, vol.188
, pp. 2233-2241
-
-
Durum, S.K.1
-
17
-
-
0032567938
-
Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor
-
Corcoran, A. E., Riddell, A., Krooshoop, D. & Venkitaraman, A. R. Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor. Nature 391, 904-907 (1998).
-
(1998)
Nature
, vol.391
, pp. 904-907
-
-
Corcoran, A.E.1
Riddell, A.2
Krooshoop, D.3
Venkitaraman, A.R.4
-
18
-
-
0033696599
-
+ T cells
-
+ T cells. Immunity 13, 59-71 (2000).
-
(2000)
Immunity
, vol.13
, pp. 59-71
-
-
Brugnera, E.1
-
19
-
-
22344438505
-
Cytokine-driven cell cycling is mediated through Cdc25A
-
Khaled, A. R. et al. Cytokine-driven cell cycling is mediated through Cdc25A. J. Cell Biol. 169, 755-763 (2005).
-
(2005)
J. Cell Biol
, vol.169
, pp. 755-763
-
-
Khaled, A.R.1
-
20
-
-
33645064841
-
IL-7 promotes T cell proliferation through destabilization of p27Kip1
-
Li, W. Q. et al. IL-7 promotes T cell proliferation through destabilization of p27Kip1. J. Exp. Med. 203, 573-582 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 573-582
-
-
Li, W.Q.1
-
21
-
-
33745207614
-
Thymic stromal lymphopoietin in normal and pathogenic T cell development and function
-
Ziegler, S. F. & Liu, Y. J. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nature Immunol. 7, 709-714 (2006).
-
(2006)
Nature Immunol
, vol.7
, pp. 709-714
-
-
Ziegler, S.F.1
Liu, Y.J.2
-
22
-
-
3242757478
-
+ T cell development
-
+ T cell development. J. Exp. Med. 200, 159-168 (2004).
-
(2004)
J. Exp. Med
, vol.200
, pp. 159-168
-
-
Al-Shami, A.1
-
23
-
-
18944379196
-
The many faces of IL-7: From lymphopoiesis to peripheral T cell maintenance
-
Fry, T. J. & Mackall, C. L. The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance. J. Immunol. 174, 6571-6576 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 6571-6576
-
-
Fry, T.J.1
Mackall, C.L.2
-
24
-
-
4143085811
-
Suppression of IL7Rα transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival
-
Park, J. H. et al. Suppression of IL7Rα transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. Immunity 21, 289-302 (2004). Shows that IL-7 downregulates IL-7Rα expression by mature T cells in vitro and in vivo, and proposes the altruistic hypothesis.
-
(2004)
Immunity
, vol.21
, pp. 289-302
-
-
Park, J.H.1
-
25
-
-
10244243681
-
Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis
-
Munitic, I. et al. Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis. Blood 104, 4165-4172 (2004). Forced expression of IL-7Rα in thymocytes is shown to inhibit thymopoiesis, and the altruistic hypothesis is proposed.
-
(2004)
Blood
, vol.104
, pp. 4165-4172
-
-
Munitic, I.1
-
26
-
-
0030831130
-
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
-
Kondo, M., Weissman, I. L. & Akashi, K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91, 661-672 (1997).
-
(1997)
Cell
, vol.91
, pp. 661-672
-
-
Kondo, M.1
Weissman, I.L.2
Akashi, K.3
-
27
-
-
0036719077
-
The earliest step in B lineage differentiation from common lymphoid progenitors is critically dependent upon interleukin 7
-
Miller, J. P. et al. The earliest step in B lineage differentiation from common lymphoid progenitors is critically dependent upon interleukin 7. J. Exp. Med. 196, 705-711 (2002).
-
(2002)
J. Exp. Med
, vol.196
, pp. 705-711
-
-
Miller, J.P.1
-
28
-
-
33644842282
-
From stem cell to T cell: One route or many?
-
Bhandoola, A. & Sambandam, A. From stem cell to T cell: one route or many? Nature Rev. Immunol. 6, 117-126 (2006).
-
(2006)
Nature Rev. Immunol
, vol.6
, pp. 117-126
-
-
Bhandoola, A.1
Sambandam, A.2
-
29
-
-
0035167690
-
Control of T cell development in vivo by subdomains within the IL-7 receptor α-chain cytoplasmic tail
-
Porter, B. O., Scibelli, P. & Malek, T. R. Control of T cell development in vivo by subdomains within the IL-7 receptor α-chain cytoplasmic tail. J. Immunol. 166, 262-269 (2001).
-
(2001)
J. Immunol
, vol.166
, pp. 262-269
-
-
Porter, B.O.1
Scibelli, P.2
Malek, T.R.3
-
30
-
-
4143151485
-
IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORγt: impact on thymocyte development
-
Yu, Q., Erman, B., Park, J. H., Feigenbaum, L. & Singer, A. IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORγt: impact on thymocyte development. J. Exp. Med. 200, 797-803 (2004). Forced expression of IL-7Rα in thymocytes is shown to inhibit thymopoiesis through interference with developmental signals.
-
Yu, Q., Erman, B., Park, J. H., Feigenbaum, L. & Singer, A. IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORγt: impact on thymocyte development. J. Exp. Med. 200, 797-803 (2004). Forced expression of IL-7Rα in thymocytes is shown to inhibit thymopoiesis through interference with developmental signals.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 797-803
-
-
Yu, Q.1
Erman, B.2
Park, J.H.3
Feigenbaum, L.4
Singer, A.5
-
31
-
-
31344480910
-
Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection
-
Yu, Q. et al. Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection. J. Exp. Med. 203, 165-175 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 165-175
-
-
Yu, Q.1
-
32
-
-
0142137130
-
Determination of lymphoid cell fate is dependent on the expression status of the IL-7 receptor
-
Purohit, S. J. et al. Determination of lymphoid cell fate is dependent on the expression status of the IL-7 receptor. EMBO J. 22, 5511-5521 (2003).
-
(2003)
EMBO J
, vol.22
, pp. 5511-5521
-
-
Purohit, S.J.1
-
33
-
-
28844433126
-
-/- bone marrow progenitors: Correction of lymphoid deficiency and induction of neutrophilia
-
-/- bone marrow progenitors: correction of lymphoid deficiency and induction of neutrophilia. Gene Ther. 12, 1761-1768 (2005).
-
(2005)
Gene Ther
, vol.12
, pp. 1761-1768
-
-
Jiang, Q.1
-
34
-
-
1642321960
-
Thymocytes between the β-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation
-
Van De Wiele, C. J. et al. Thymocytes between the β-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation. J. Immunol. 172, 4235-4244 (2004).
-
(2004)
J. Immunol
, vol.172
, pp. 4235-4244
-
-
Van De Wiele, C.J.1
-
35
-
-
0031587875
-
-/- mice
-
-/- mice. Cell 89, 1011-1019 (1997).
-
(1997)
Cell
, vol.89
, pp. 1011-1019
-
-
Maraskovsky, E.1
-
36
-
-
0030787787
-
Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common γ chain-deficient mice
-
Kondo, M., Akashi, K., Domen, J., Sugamura, K. & Weissman, I. L. Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common γ chain-deficient mice. Immunity 7, 155-162 (1997).
-
(1997)
Immunity
, vol.7
, pp. 155-162
-
-
Kondo, M.1
Akashi, K.2
Domen, J.3
Sugamura, K.4
Weissman, I.L.5
-
37
-
-
0036849781
-
Bax deficiency partially corrects interleukin-7 receptor α deficiency
-
Khaled, A. R. et al. Bax deficiency partially corrects interleukin-7 receptor α deficiency. Immunity 17, 561-573 (2002).
-
(2002)
Immunity
, vol.17
, pp. 561-573
-
-
Khaled, A.R.1
-
38
-
-
0343812092
-
IL-7 receptor and VDJ recombination: trophic versus mechanistic actions
-
Candeias, S., Muegge, K. & Durum, S. K. IL-7 receptor and VDJ recombination: trophic versus mechanistic actions. Immunity 6, 501-508 (1997).
-
(1997)
Immunity
, vol.6
, pp. 501-508
-
-
Candeias, S.1
Muegge, K.2
Durum, S.K.3
-
39
-
-
3042716781
-
Distinct regions of the interleukin-7 receptor regulate different Bcl2 family members
-
Jiang, Q. et al. Distinct regions of the interleukin-7 receptor regulate different Bcl2 family members. Mol. Cell. Biol. 24, 6501-6513 (2004).
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 6501-6513
-
-
Jiang, Q.1
-
40
-
-
3242747324
-
Regulation of thymus size by competition for stromal niches among early T cell progenitors
-
Prockop, S. E. & Petrie, H. T. Regulation of thymus size by competition for stromal niches among early T cell progenitors. J. Immunol. 173, 1604-1611 (2004).
-
(2004)
J. Immunol
, vol.173
, pp. 1604-1611
-
-
Prockop, S.E.1
Petrie, H.T.2
-
41
-
-
0036278490
-
Interleukin-7 inhibits pre-T-cell differentiation induced by the pre-T-cell receptor signal and the effect is mimicked by hGM-CSF in hGM-CSF receptor transgenic mice
-
Yasuda, Y., Kaneko, A., Nishijima, I., Miyatake, S. & Arai, K. Interleukin-7 inhibits pre-T-cell differentiation induced by the pre-T-cell receptor signal and the effect is mimicked by hGM-CSF in hGM-CSF receptor transgenic mice. Immunology 106, 212-221 (2002).
-
(2002)
Immunology
, vol.106
, pp. 212-221
-
-
Yasuda, Y.1
Kaneko, A.2
Nishijima, I.3
Miyatake, S.4
Arai, K.5
-
42
-
-
0035881243
-
Human recent thymic emigrants- identification, expansion, and survival characteristics
-
Hassan, J. & Reen, D. J. Human recent thymic emigrants- identification, expansion, and survival characteristics. J. Immunol. 167, 1970-1976 (2001).
-
(2001)
J. Immunol
, vol.167
, pp. 1970-1976
-
-
Hassan, J.1
Reen, D.J.2
-
44
-
-
0032402257
-
+ T cells enables preservation of a naive repertoire
-
+ T cells enables preservation of a naive repertoire. J. Immunol. 161, 5909-5917 (1998).
-
(1998)
J. Immunol
, vol.161
, pp. 5909-5917
-
-
Soares, M.V.1
-
46
-
-
0036498562
-
Positive effects of glucocorticoids on T cell function by up-regulation of IL-7 receptor α
-
Franchimont, D. et al. Positive effects of glucocorticoids on T cell function by up-regulation of IL-7 receptor α. J. Immunol. 168, 2212-2218 (2002). Shows that TCR activation downregulates IL-7Rα expression.
-
(2002)
J. Immunol.
, vol.168
, pp. 2212-2218
-
-
Franchimont, D.1
-
47
-
-
0347382593
-
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
-
Kaech, S. M. et al. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nature Immunol. 4, 1191-1198 (2003). Shows that memory T cells derive from a subset of activated T cells that do not downregulate IL-7Rα expression.
-
(2003)
Nature Immunol.
, vol.4
, pp. 1191-1198
-
-
Kaech, S.M.1
-
49
-
-
2142756661
-
CD8αα-mediated survival and differentiation of CD8 memory T cell precursors
-
Madakamutil, L. T. et al. CD8αα-mediated survival and differentiation of CD8 memory T cell precursors. Science 304, 590-593 (2004).
-
(2004)
Science
, vol.304
, pp. 590-593
-
-
Madakamutil, L.T.1
-
50
-
-
27144441379
-
Cutting edge: Memory CD8 T cell maturation occurs independently of CD8αα
-
Chandele, A. & Kaech, S. M. Cutting edge: memory CD8 T cell maturation occurs independently of CD8αα. J. Immunol. 175, 5619-5623 (2005).
-
(2005)
J. Immunol
, vol.175
, pp. 5619-5623
-
-
Chandele, A.1
Kaech, S.M.2
-
51
-
-
33749131253
-
Cutting edge: IL-7-independent regulation of IL-7 receptor α expression and memory CD8 T cell development
-
Klonowski, K. D., Williams, K. J., Marzo, A. L. & Lefrancois, L. Cutting edge: IL-7-independent regulation of IL-7 receptor α expression and memory CD8 T cell development. J. Immunol. 177, 4247-4251 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 4247-4251
-
-
Klonowski, K.D.1
Williams, K.J.2
Marzo, A.L.3
Lefrancois, L.4
-
52
-
-
0033554726
-
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
-
Sallusto, F., Lenig, D., Forster, R., Lipp, M. & Lanzavecchia, A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401, 708-712 (1999).
-
(1999)
Nature
, vol.401
, pp. 708-712
-
-
Sallusto, F.1
Lenig, D.2
Forster, R.3
Lipp, M.4
Lanzavecchia, A.5
-
54
-
-
0037124366
-
+ cells
-
+ cells. J. Exp. Med. 195, 1523-1532 (2002).
-
(2002)
J. Exp. Med
, vol.195
, pp. 1523-1532
-
-
Tan, J.T.1
-
55
-
-
33748691799
-
Do CD8 effector cells need IL-7R expression to become resting memory cells?
-
Buentke, E. et al. Do CD8 effector cells need IL-7R expression to become resting memory cells? Blood 108, 1949-1956 (2006).
-
(2006)
Blood
, vol.108
, pp. 1949-1956
-
-
Buentke, E.1
-
57
-
-
33749009709
-
+ T cells leads to reversible immune dysfunction
-
+ T cells leads to reversible immune dysfunction. Nature Med. 12, 1198-1202 (2006).
-
(2006)
Nature Med
, vol.12
, pp. 1198-1202
-
-
Trautmann, L.1
-
58
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
Day, C. L. et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443, 350-354 (2006).
-
(2006)
Nature
, vol.443
, pp. 350-354
-
-
Day, C.L.1
-
59
-
-
0028589592
-
Dysregulation of interleukin-7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection
-
Carini, C., McLane, M. F., Mayer, K. H. & Essex, M. Dysregulation of interleukin-7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection. Eur. J. Immunol. 24, 2927-2934 (1994).
-
(1994)
Eur. J. Immunol
, vol.24
, pp. 2927-2934
-
-
Carini, C.1
McLane, M.F.2
Mayer, K.H.3
Essex, M.4
-
61
-
-
0037119046
-
Features of 'CD4-exploders', HIV-positive patients with an optimal immune reconstitution after potent antiretroviral therapy
-
Mussini, C. et al. Features of 'CD4-exploders', HIV-positive patients with an optimal immune reconstitution after potent antiretroviral therapy. AIDS 16, 1609-1616 (2002).
-
(2002)
AIDS
, vol.16
, pp. 1609-1616
-
-
Mussini, C.1
-
62
-
-
15844411342
-
Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation
-
Lang, K. S. et al. Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation. Eur. J. Immunol. 35, 738-745 (2005).
-
(2005)
Eur. J. Immunol
, vol.35
, pp. 738-745
-
-
Lang, K.S.1
-
63
-
-
24744444751
-
+ T cells
-
+ T cells. Blood 106, 2091-2098 (2005).
-
(2005)
Blood
, vol.106
, pp. 2091-2098
-
-
van Leeuwen, E.M.1
-
64
-
-
18544362048
-
+ memory T cell responses in elderly persons
-
+ memory T cell responses in elderly persons. J. Infect. Dis. 191, 1710-1718 (2005).
-
(2005)
J. Infect. Dis
, vol.191
, pp. 1710-1718
-
-
de Bree, G.J.1
-
65
-
-
20044382810
-
+ T cells in HIV-infected individuals
-
+ T cells in HIV-infected individuals. J. Immunol. 174, 2900-2909 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 2900-2909
-
-
Paiardini, M.1
-
66
-
-
32944455546
-
+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation
-
+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation. Eur. J. Immunol. 36, 336-344 (2006).
-
(2006)
Eur. J. Immunol
, vol.36
, pp. 336-344
-
-
Koesters, S.A.1
-
67
-
-
33645072224
-
CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients - reversal by highly active anti-retroviral therapy (HAART)
-
Colle, J. H. et al. CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients - reversal by highly active anti-retroviral therapy (HAART). Clin. Exp. Immunol. 143, 398-403 (2006).
-
(2006)
Clin. Exp. Immunol
, vol.143
, pp. 398-403
-
-
Colle, J.H.1
-
68
-
-
33645220927
-
+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection
-
+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection. J. Virol. 80, 3532-3540 (2006).
-
(2006)
J. Virol
, vol.80
, pp. 3532-3540
-
-
Boettler, T.1
-
70
-
-
0037124328
-
+ T cells
-
+ T cells. J. Exp. Med. 195, 1533-1539 (2002).
-
(2002)
J. Exp. Med
, vol.195
, pp. 1533-1539
-
-
Kieper, W.C.1
-
71
-
-
0038487052
-
Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells
-
Seddon, B., Tomlinson, P. & Zamoyska, R. Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells. Nature Immunol. 4, 680-686 (2003).
-
(2003)
Nature Immunol
, vol.4
, pp. 680-686
-
-
Seddon, B.1
Tomlinson, P.2
Zamoyska, R.3
-
72
-
-
0347594000
-
IL-7 promotes the transition of CD4 effectors to persistent memory cells
-
Li, J., Huston, G. & Swain, S. L. IL-7 promotes the transition of CD4 effectors to persistent memory cells. J. Exp. Med. 198, 1807-1815 (2003).
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1807-1815
-
-
Li, J.1
Huston, G.2
Swain, S.L.3
-
73
-
-
20444410453
-
Transcriptional regulation of the mouse IL-7 receptor α promoter by glucocorticoid receptor
-
Lee, H. C., Shibata, H., Ogawa, S., Maki, K. & Ikuta, K. Transcriptional regulation of the mouse IL-7 receptor α promoter by glucocorticoid receptor. J. Immunol. 174, 7800-7806 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 7800-7806
-
-
Lee, H.C.1
Shibata, H.2
Ogawa, S.3
Maki, K.4
Ikuta, K.5
-
74
-
-
0036199657
-
PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors
-
DeKoter, R. P., Lee, H. J. & Singh, H. PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity 16, 297-309 (2002).
-
(2002)
Immunity
, vol.16
, pp. 297-309
-
-
DeKoter, R.P.1
Lee, H.J.2
Singh, H.3
-
75
-
-
5044249424
-
Assembling a gene regulatory network for specification of the B cell fate
-
Medina, K. L. et al. Assembling a gene regulatory network for specification of the B cell fate. Dev. Cell 7, 607-617 (2004).
-
(2004)
Dev. Cell
, vol.7
, pp. 607-617
-
-
Medina, K.L.1
-
76
-
-
17044440153
-
Contingent gene regulatory networks and B cell fate specification
-
Singh, H., Medina, K. L. & Pongubala, J. M. Contingent gene regulatory networks and B cell fate specification. Proc. Natl Acad. Sci. USA 102, 4949-4953 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 4949-4953
-
-
Singh, H.1
Medina, K.L.2
Pongubala, J.M.3
-
77
-
-
0032784934
-
Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage
-
Anderson, M. K., Hernandez-Hoyos, G., Diamond, R. A. & Rothenberg, E. V. Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage. Development 126, 3131-3148 (1999).
-
(1999)
Development
, vol.126
, pp. 3131-3148
-
-
Anderson, M.K.1
Hernandez-Hoyos, G.2
Diamond, R.A.3
Rothenberg, E.V.4
-
78
-
-
5444249783
-
GA binding protein regulates interleukin 7 receptor α-chain gene expression in T cells
-
Xue, H. H. et al. GA binding protein regulates interleukin 7 receptor α-chain gene expression in T cells. Nature Immunol. 5, 1036-1044 (2004).
-
(2004)
Nature Immunol
, vol.5
, pp. 1036-1044
-
-
Xue, H.H.1
-
79
-
-
2942709643
-
The ETS transcription factor GABPα is essential for early embryogenesis
-
Ristevski, S. et al. The ETS transcription factor GABPα is essential for early embryogenesis. Mol. Cell. Biol. 24, 5844-5849 (2004).
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 5844-5849
-
-
Ristevski, S.1
-
80
-
-
12344329557
-
Identification and expression analysis of alternative transcripts of the mouse GA-binding protein (Gabp) subunits α and β
-
O'Leary, D. A., Koleski, D., Kola, I., Hertzog, P. J. & Ristevski, S. Identification and expression analysis of alternative transcripts of the mouse GA-binding protein (Gabp) subunits α and β. Gene 344, 79-92 (2005).
-
(2005)
Gene
, vol.344
, pp. 79-92
-
-
O'Leary, D.A.1
Koleski, D.2
Kola, I.3
Hertzog, P.J.4
Ristevski, S.5
-
81
-
-
0036135774
-
Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells
-
Galon, J. et al. Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells. FASEB J. 16, 61-71 (2002).
-
(2002)
FASEB J
, vol.16
, pp. 61-71
-
-
Galon, J.1
-
82
-
-
0042767698
-
Disruption of glucocorticoid receptor exon 2 yields a ligand-responsive C-terminal fragment that regulates gene expression
-
Mittelstadt, P. R. & Ashwell, J. D. Disruption of glucocorticoid receptor exon 2 yields a ligand-responsive C-terminal fragment that regulates gene expression. Mol. Endocrinol. 17, 1534-1542 (2003).
-
(2003)
Mol. Endocrinol
, vol.17
, pp. 1534-1542
-
-
Mittelstadt, P.R.1
Ashwell, J.D.2
-
83
-
-
0025829407
-
Organization of the murine and human interleukin-7 receptor genes: Two mRNAs generated by differential splicing and presence of a type I-interferon-inducible promoter
-
Pleiman, C. M. et al. Organization of the murine and human interleukin-7 receptor genes: two mRNAs generated by differential splicing and presence of a type I-interferon-inducible promoter. Mol. Cell. Biol. 11, 3052-3059 (1991).
-
(1991)
Mol. Cell. Biol
, vol.11
, pp. 3052-3059
-
-
Pleiman, C.M.1
-
84
-
-
20444478655
-
Identification of direct genomic targets downstream of the nuclear factor-κB transcription factor mediating tumor necrosis factor signaling
-
Tian, B., Nowak, D. E., Jamaluddin, M., Wang, S. & Brasier, A. R. Identification of direct genomic targets downstream of the nuclear factor-κB transcription factor mediating tumor necrosis factor signaling. J. Biol. Chem. 280, 17435-17448 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 17435-17448
-
-
Tian, B.1
Nowak, D.E.2
Jamaluddin, M.3
Wang, S.4
Brasier, A.R.5
-
85
-
-
0037371433
-
Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor α expression, and T cell lineage commitment
-
Doan, L. L. et al. Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor α expression, and T cell lineage commitment. J. Immunol. 170, 2356-2366 (2003).
-
(2003)
J. Immunol
, vol.170
, pp. 2356-2366
-
-
Doan, L.L.1
-
86
-
-
0037109077
-
IL-2 negatively regulates IL-7 receptor α chain expression in activated T lymphocytes
-
Xue, H. H. et al. IL-2 negatively regulates IL-7 receptor α chain expression in activated T lymphocytes. Proc. Natl Acad. Sci. USA 99, 13759-13764 (2002). Shows that IL-7Rα expression is downregulated by IL-2, a relative of IL-7.
-
(2002)
Proc. Natl Acad. Sci.
, vol.99
, pp. 13759-13764
-
-
Xue, H.H.1
-
87
-
-
0034657746
-
κ-opioid regulation of thymocyte IL-7 receptor and C-C chemokine receptor 2 expression
-
Zhang, L. & Rogers, T. J. κ-opioid regulation of thymocyte IL-7 receptor and C-C chemokine receptor 2 expression. J. Immunol. 164, 5088-5093 (2000).
-
(2000)
J. Immunol
, vol.164
, pp. 5088-5093
-
-
Zhang, L.1
Rogers, T.J.2
-
90
-
-
0041344313
-
Mucosal T cells expressing high levels of IL-7 receptor are potential targets for treatment of chronic colitis
-
Yamazaki, M. et al. Mucosal T cells expressing high levels of IL-7 receptor are potential targets for treatment of chronic colitis. J. Immunol. 171, 1556-1563 (2003).
-
(2003)
J. Immunol
, vol.171
, pp. 1556-1563
-
-
Yamazaki, M.1
-
91
-
-
1542373668
-
Overexpression of IL-7Rα provides a competitive advantage during early T-cell development
-
Laouar, Y., Crispe, I. N. & Flavell, R. A. Overexpression of IL-7Rα provides a competitive advantage during early T-cell development. Blood 103, 1985-1994 (2004).
-
(2004)
Blood
, vol.103
, pp. 1985-1994
-
-
Laouar, Y.1
Crispe, I.N.2
Flavell, R.A.3
-
92
-
-
0027401239
-
Cutaneous lymphoproliferation and lymphomas in interleukin 7 transgenic mice
-
Rich, B. E., Campos-Torres, J., Tepper, R. I., Moreadith, R. W. & Leder, P. Cutaneous lymphoproliferation and lymphomas in interleukin 7 transgenic mice. J. Exp. Med. 177, 305-316 (1993).
-
(1993)
J. Exp. Med
, vol.177
, pp. 305-316
-
-
Rich, B.E.1
Campos-Torres, J.2
Tepper, R.I.3
Moreadith, R.W.4
Leder, P.5
-
93
-
-
0028924203
-
Lymphoproliferative disorders in IL-7 transgenic mice: Expansion of immature B cells which retain macrophage potential
-
Fisher, A. G., Burdet, C., Bunce, C., Merkenschlager, M. & Ceredig, R. Lymphoproliferative disorders in IL-7 transgenic mice: expansion of immature B cells which retain macrophage potential. Int. Immunol. 7, 415-423 (1995).
-
(1995)
Int. Immunol
, vol.7
, pp. 415-423
-
-
Fisher, A.G.1
Burdet, C.2
Bunce, C.3
Merkenschlager, M.4
Ceredig, R.5
-
94
-
-
3042709504
-
IL-7-dependent homeostatic proliferation in the presence of a large number of T cells in gld mice
-
Aranami, T., Iclozan, C., Iwabuchi, K. & Onoe, K. IL-7-dependent homeostatic proliferation in the presence of a large number of T cells in gld mice. Microbiol. Immunol. 48, 477-484 (2004).
-
(2004)
Microbiol. Immunol.
, vol.48
, pp. 477-484
-
-
Aranami, T.1
Iclozan, C.2
Iwabuchi, K.3
Onoe, K.4
-
95
-
-
0033485342
-
Lymphoid-restricted development from multipotent candidate murine stem cells: Distinct and complimentary functions of the c-kit and flt3-ligands
-
Borge, O. J., Adolfsson, J. & Jacobsen, A. M. Lymphoid-restricted development from multipotent candidate murine stem cells: distinct and complimentary functions of the c-kit and flt3-ligands. Blood 94, 3781-3790 (1999).
-
(1999)
Blood
, vol.94
, pp. 3781-3790
-
-
Borge, O.J.1
Adolfsson, J.2
Jacobsen, A.M.3
-
96
-
-
0042383366
-
+ lymphoid-restricted bone marrow cells with T precursor potential
-
+ lymphoid-restricted bone marrow cells with T precursor potential. Nature Immunol. 4, 866-873 (2003).
-
(2003)
Nature Immunol
, vol.4
, pp. 866-873
-
-
Martin, C.H.1
-
97
-
-
0024282606
-
Stimulation of B-cell progenitors by cloned murine interleukin-7
-
Namen, A. E. et al. Stimulation of B-cell progenitors by cloned murine interleukin-7. Nature 333, 571-573 (1988).
-
(1988)
Nature
, vol.333
, pp. 571-573
-
-
Namen, A.E.1
-
98
-
-
0025868702
-
Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
-
Hardy, R. R., Carmack, C. E., Shinton, S. A., Kemp, J. D. & Hayakawa, K. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173, 1213-1225 (1991).
-
(1991)
J. Exp. Med
, vol.173
, pp. 1213-1225
-
-
Hardy, R.R.1
Carmack, C.E.2
Shinton, S.A.3
Kemp, J.D.4
Hayakawa, K.5
-
100
-
-
0031872205
-
Expression of recombination activating genes in germinal center B cells: Involvement of interleukin 7 (IL-7) and the IL-7 receptor
-
Hikida, M. et al. Expression of recombination activating genes in germinal center B cells: involvement of interleukin 7 (IL-7) and the IL-7 receptor. J. Exp. Med. 188, 365-372 (1998).
-
(1998)
J. Exp. Med
, vol.188
, pp. 365-372
-
-
Hikida, M.1
-
101
-
-
0034684650
-
Antigen-independent appearance of recombination activating gene (RAG)-positive bone marrow B cells in the spleens of immunized mice
-
Gartner, F., Alt, F. W., Monroe, R. J. & Seidl, K. J. Antigen-independent appearance of recombination activating gene (RAG)-positive bone marrow B cells in the spleens of immunized mice. J. Exp. Med. 192, 1745-1754 (2000).
-
(2000)
J. Exp. Med
, vol.192
, pp. 1745-1754
-
-
Gartner, F.1
Alt, F.W.2
Monroe, R.J.3
Seidl, K.J.4
-
102
-
-
2542461255
-
Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution
-
Buckley, R. H. Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution. Annu. Rev. Immunol. 22, 625-655 (2004).
-
(2004)
Annu. Rev. Immunol
, vol.22
, pp. 625-655
-
-
Buckley, R.H.1
-
103
-
-
0029812552
-
Interleukin 7 independent development of human B cells
-
Prieyl, J. A. & LeBien, T. W. Interleukin 7 independent development of human B cells. Proc. Natl Acad. Sci. USA 93, 10348-10353 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 10348-10353
-
-
Prieyl, J.A.1
LeBien, T.W.2
-
104
-
-
0025837192
-
Development of a bone marrow culture for maintenance and growth of normal human B cell precursors
-
Wolf, M. L., Buckley, J. A., Goldfarb, A., Law, C. L. & LeBien, T. W. Development of a bone marrow culture for maintenance and growth of normal human B cell precursors. J. Immunol. 147, 3324-3330 (1991).
-
(1991)
J. Immunol
, vol.147
, pp. 3324-3330
-
-
Wolf, M.L.1
Buckley, J.A.2
Goldfarb, A.3
Law, C.L.4
LeBien, T.W.5
-
105
-
-
0025985529
-
Interleukin-7 induces the proliferation of normal human B-cell precursors
-
Saeland, S. et al. Interleukin-7 induces the proliferation of normal human B-cell precursors. Blood 78, 2229-2238 (1991).
-
(1991)
Blood
, vol.78
, pp. 2229-2238
-
-
Saeland, S.1
-
106
-
-
0027437387
-
Myofibroblastic stromal cells isolated from human bone marrow induce the proliferation of both early myeloid and B-lymphoid cells
-
Moreau, I. et al. Myofibroblastic stromal cells isolated from human bone marrow induce the proliferation of both early myeloid and B-lymphoid cells. Blood 82, 2396-2405 (1993).
-
(1993)
Blood
, vol.82
, pp. 2396-2405
-
-
Moreau, I.1
-
107
-
-
0027511665
-
Culture of human fetal B-cell precursors on bone marrow stroma maintains highly proliferative CD20dim cells
-
Moreau, I., Duvert, V., Banchereau, J. & Saeland, S. Culture of human fetal B-cell precursors on bone marrow stroma maintains highly proliferative CD20dim cells. Blood 81, 1170-1178 (1993).
-
(1993)
Blood
, vol.81
, pp. 1170-1178
-
-
Moreau, I.1
Duvert, V.2
Banchereau, J.3
Saeland, S.4
-
108
-
-
28244453738
-
Murine and human IL-7 activate STAT5 and induce proliferation of normal human pro-B cells
-
Johnson, S. E., Shah, N., Panoskaltsis-Mortari, A. & LeBien, T. W. Murine and human IL-7 activate STAT5 and induce proliferation of normal human pro-B cells. J. Immunol. 175, 7325-7331 (2005).
-
(2005)
J. Immunol
, vol.175
, pp. 7325-7331
-
-
Johnson, S.E.1
Shah, N.2
Panoskaltsis-Mortari, A.3
LeBien, T.W.4
-
109
-
-
0028878890
-
The growth response to IL-7 during normal human B cell ontogeny is restricted to B-lineage cells expressing CD34
-
Dittel, B. N. & LeBien, T. W. The growth response to IL-7 during normal human B cell ontogeny is restricted to B-lineage cells expressing CD34. J. Immunol. 154, 58-67 (1995).
-
(1995)
J. Immunol
, vol.154
, pp. 58-67
-
-
Dittel, B.N.1
LeBien, T.W.2
-
110
-
-
0031587826
-
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
-
Akashi, K., Kondo, M., von Freeden-Jeffry, U., Murray, R. & Weissman, I. L. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89, 1033-1041 (1997).
-
(1997)
Cell
, vol.89
, pp. 1033-1041
-
-
Akashi, K.1
Kondo, M.2
von Freeden-Jeffry, U.3
Murray, R.4
Weissman, I.L.5
-
111
-
-
0029983731
-
The interleukin-7 receptor α chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis
-
Corcoran, A. E. et al. The interleukin-7 receptor α chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis. EMBO J. 15, 1924-1932 (1996).
-
(1996)
EMBO J
, vol.15
, pp. 1924-1932
-
-
Corcoran, A.E.1
-
112
-
-
17144422917
-
Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors
-
Dias, S., Silva, H. Jr, Cumano, A. & Vieira, P. Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors. J. Exp. Med. 201, 971-979 (2005).
-
(2005)
J. Exp. Med
, vol.201
, pp. 971-979
-
-
Dias, S.1
Silva Jr, H.2
Cumano, A.3
Vieira, P.4
-
113
-
-
18244386710
-
IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF
-
Kikuchi, K., Lai, A. Y., Hsu, C. L. & Kondo, M. IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF. J. Exp. Med. 201, 1197-1203 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1197-1203
-
-
Kikuchi, K.1
Lai, A.Y.2
Hsu, C.L.3
Kondo, M.4
-
114
-
-
0034651566
-
Murine pro-B cells require IL-7 and its receptor complex to up-regulate IL-7Rα, terminal deoxynucleotidyltransferase, and cμ expression
-
Wei, C., Zeff, R. & Goldschneider, I. Murine pro-B cells require IL-7 and its receptor complex to up-regulate IL-7Rα, terminal deoxynucleotidyltransferase, and cμ expression. J. Immunol. 164, 1961-1970 (2000).
-
(2000)
J. Immunol
, vol.164
, pp. 1961-1970
-
-
Wei, C.1
Zeff, R.2
Goldschneider, I.3
-
116
-
-
32544448486
-
IL-7: A key regulator of B lymphopoiesis
-
Milne, C. D. & Paige, C. J. IL-7: a key regulator of B lymphopoiesis. Semin. Immunol. 18, 20-30 (2006).
-
(2006)
Semin. Immunol
, vol.18
, pp. 20-30
-
-
Milne, C.D.1
Paige, C.J.2
|