-
1
-
-
0036015236
-
Mecanismo de acción de las protemas que se unen a los elementos regulatorios de esteroles (SREBPs) en la biosíntesis del colesterol y ácidos grasos
-
Manzano N, Torres N, Tovar AR. Mecanismo de acción de las protemas que se unen a los elementos regulatorios de esteroles (SREBPs) en la biosíntesis del colesterol y ácidos grasos. Rev Invest Clin 2002; 54: 145-53.
-
(2002)
Rev. Invest. Clin.
, vol.54
, pp. 145-153
-
-
Manzano, N.1
Torres, N.2
Tovar, A.R.3
-
2
-
-
0034993832
-
Peroxisome proliferator-activated receptors: From transcriptional control to clinical practice
-
Pineda Torra I, Chinetti G, Duval C, Fruchart JC, Staels B. Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice. Curr Op Lipidol 2001; 12: 245-54.
-
(2001)
Curr. Op. Lipidol.
, vol.12
, pp. 245-254
-
-
Pineda Torra, I.1
Chinetti, G.2
Duval, C.3
Fruchart, J.C.4
Staels, B.5
-
3
-
-
0033542873
-
Medical significance of peroxisome proliferator-activated receptors
-
Vamecq J, Latruffe N. Medical significance of peroxisome proliferator-activated receptors. Lancet 1999; 354: 141-8.
-
(1999)
Lancet
, vol.354
, pp. 141-148
-
-
Vamecq, J.1
Latruffe, N.2
-
4
-
-
0013897667
-
Peroxisomes (microbodies and related particles)
-
de Duve C, Baudhuin P. Peroxisomes (microbodies and related particles). Phisiol Rev 1966; 46: 323-57.
-
(1966)
Phisiol. Rev.
, vol.46
, pp. 323-357
-
-
de Duve, C.1
Baudhuin, P.2
-
5
-
-
0001921897
-
Metabolic role of mammalian peroxisomes
-
Basingstoke: Taylor and Francis
-
Mannaerts GP, Van Veldhoven PP. Metabolic role of mammalian peroxisomes. Basingstoke: Taylor and Francis. 1993.
-
(1993)
-
-
Mannaerts, G.P.1
Van Veldhoven, P.P.2
-
7
-
-
0019349080
-
Metabolic pathways in persoxisomes and glyoxisomes
-
Tolbert NE. Metabolic pathways in persoxisomes and glyoxisomes. Ann Rev Bioehem 1981; 50: 133-7.
-
(1981)
Ann. Rev. Bioehem.
, vol.50
, pp. 133-137
-
-
Tolbert, N.E.1
-
9
-
-
0018888058
-
Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens
-
Reddy JK, Azarnoff DL, Hignite CE. Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature 1980; 283: 397-8.
-
(1980)
Nature
, vol.283
, pp. 397-398
-
-
Reddy, J.K.1
Azarnoff, D.L.2
Hignite, C.E.3
-
10
-
-
0023202190
-
Peroxisome proliferation and hepatocarcinogenesis
-
Rao MS, Reddy JK. Peroxisome proliferation and hepatocarcinogenesis. Carcinogenesis 1987; 8: 631-6.
-
(1987)
Carcinogenesis
, vol.8
, pp. 631-636
-
-
Rao, M.S.1
Reddy, J.K.2
-
11
-
-
0027412583
-
Comparative effects of dehydroepiandrosterone and related steroids on peroxisome proliferation in rat liver
-
Rao MS, Ide H, Alvares L, Subbarao V, Reddy JK, Hechter O, Yeldandi AV. Comparative effects of dehydroepiandrosterone and related steroids on peroxisome proliferation in rat liver. Life Sci 1993; 52: 1709-16.
-
(1993)
Life Sci.
, vol.52
, pp. 1709-1716
-
-
Rao, M.S.1
Ide, H.2
Alvares, L.3
Subbarao, V.4
Reddy, J.K.5
Hechter, O.6
Yeldandi, A.V.7
-
13
-
-
0020574070
-
Severe plasmalogen deficiency in tissues of infants without peroxisomes (Zellweger syndrome)
-
Heymans HSA, Schutgens RBH, Tan R, van den Bosch H, Borst P. Severe plasmalogen deficiency in tissues of infants without peroxisomes (Zellweger syndrome). Nature 1983; 6: 69-70.
-
(1983)
Nature
, vol.6
, pp. 69-70
-
-
Heymans, H.S.A.1
Schutgens, R.B.H.2
Tan, R.3
van den Bosch, H.4
Borst, P.5
-
14
-
-
0342528190
-
A fatty acyl-CoA oxidizing systems in rat liver peroxisomes; enhancemente by clofibrate, a hypolipidemic drug
-
Lazarow PB, de Dove C. A fatty acyl-CoA oxidizing systems in rat liver peroxisomes; enhancemente by clofibrate, a hypolipidemic drug. Proc Natl Acad Sci USA 1976; 73: 2043-6.
-
(1976)
Proc. Natl. Acad. Sci. USA
, vol.73
, pp. 2043-2046
-
-
Lazarow, P.B.1
de Dove, C.2
-
15
-
-
0022446395
-
Transcriptional regulation of peroxisome fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-dehydroxyacyl-CoA dehydrogenase in rat liver by peroxisome/ proliferators
-
Reddy JK, Goel SK, Nemali MR, Carrino JJ, Laffler TG, Reddy MK, Sperbeck SJ, Osumi T, Hashimoto T, Lalwani ND, et al. Transcriptional regulation of peroxisome fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-dehydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators. Proc Natl Acad Sci USA 1986; 83: 1747-51.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 1747-1751
-
-
Reddy, J.K.1
Goel, S.K.2
Nemali, M.R.3
Carrino, J.J.4
Laffler, T.G.5
Reddy, M.K.6
Sperbeck, S.J.7
Osumi, T.8
Hashimoto, T.9
Lalwani, N.D.10
-
16
-
-
0034584717
-
PPAR alpha-mediated responses in the rodent liver: A holistic biochemical view
-
Chevalier S, Macdonald N, Roberts RA. PPAR alpha-mediated responses in the rodent liver: a holistic biochemical view. Curr Protein Pept Sci 2000; 1: 325-38.
-
(2000)
Curr. Protein Pept. Sci.
, vol.1
, pp. 325-338
-
-
Chevalier, S.1
Macdonald, N.2
Roberts, R.A.3
-
17
-
-
0025132245
-
Activation of a member of the steroid receptor hormone superfamily by peroxisome proliferators
-
Issemann I, Green S. Activation of a member of the steroid receptor hormone superfamily by peroxisome proliferators. Nature 1990; 347: 645-50.
-
(1990)
Nature
, vol.347
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
18
-
-
0029994543
-
Role of the peroxisome proliferator activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
-
Schoonjans K, Staels B, Auwerx J. Role of the peroxisome proliferator activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression. J Lipid Res 1996; 37: 905-25.
-
(1996)
J. Lipid. Res.
, vol.37
, pp. 905-925
-
-
Schoonjans, K.1
Staels, B.2
Auwerx, J.3
-
19
-
-
0033406251
-
Peroxisome proliferators: Mechanisms of adverse effects in rodents and molecular basis for species differences
-
Roberts RA. Peroxisome proliferators: mechanisms of adverse effects in rodents and molecular basis for species differences. Arch Toxicol 1999; 73: 413-8.
-
(1999)
Arch. Toxicol.
, vol.73
, pp. 413-418
-
-
Roberts, R.A.1
-
20
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
Issemann I, Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 1990; 347: 645-50.
-
(1990)
Nature
, vol.347
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
21
-
-
0032867442
-
Peroxisome proliferator-activated receptors: A family of lipid-activated transcription factors
-
Clarke SD, Thuillier P, Baillie R, Sha X. Peroxisome proliferator-activated receptors: a family of lipid-activated transcription factors. Am J Clin Nutr 1999; 70: 566-71.
-
(1999)
Am. J. Clin. Nutr.
, vol.70
, pp. 566-571
-
-
Clarke, S.D.1
Thuillier, P.2
Baillie, R.3
Sha, X.4
-
22
-
-
0029562554
-
The RXR heterodimers and orphan receptors
-
Mangelsdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell 1995; 83: 841-50.
-
(1995)
Cell
, vol.83
, pp. 841-850
-
-
Mangelsdorf, D.J.1
Evans, R.M.2
-
23
-
-
17444442152
-
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
-
Mukherjee R, Davies PJA, Crombie DL. Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists. Nature 1997; 386: 407-10.
-
(1997)
Nature
, vol.386
, pp. 407-410
-
-
Mukherjee, R.1
Davies, P.J.A.2
Crombie, D.L.3
-
24
-
-
0032433287
-
Cytosolic and nuclear distribution of PPARγ2 in differentiating 3T3-L1 preadipocytes
-
Thuillier P, Baillie R, Sha X, Clarke SD. Cytosolic and nuclear distribution of PPARγ2 in differentiating 3T3-L1 preadipocytes. J Lipid Res 1998; 39: 2329-38.
-
(1998)
J. Lipid. Res.
, vol.39
, pp. 2329-2338
-
-
Thuillier, P.1
Baillie, R.2
Sha, X.3
Clarke, S.D.4
-
25
-
-
0027290892
-
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signalling
-
Miyata KS, Zhang B, Marcus SL, Capone JP, Rachubinski RA. Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signalling. J Biol Chem 1993; 268: 19169-72.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 19169-19172
-
-
Miyata, K.S.1
Zhang, B.2
Marcus, S.L.3
Capone, J.P.4
Rachubinski, R.A.5
-
26
-
-
0028005206
-
Transactivation of the peroxisome proliferatoractivated receptor is differentially modulated by hepatocyte nuclear factor-4
-
Winrow CJ, Marcus SL, Miyata KS, Zhang B, Capone JP, Rachubinski RA. Transactivation of the peroxisome proliferatoractivated receptor is differentially modulated by hepatocyte nuclear factor-4. Gene Expr 1994; 4: 53-62.
-
(1994)
Gene Expr.
, vol.4
, pp. 53-62
-
-
Winrow, C.J.1
Marcus, S.L.2
Miyata, K.S.3
Zhang, B.4
Capone, J.P.5
Rachubinski, R.A.6
-
27
-
-
0028970523
-
Antagonism of COUP-TF and PPARα,/RXRα on the activation of the malic enzyme gene promoter-modulation by 9-cis RA
-
Baes M, Castelein H, Desmet L, Declercq PE. Antagonism of COUP-TF and PPARα,/RXRα on the activation of the malic enzyme gene promoter-modulation by 9-cis RA. Biochem Biophys Res Commun 1995; 215: 19169-72.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.215
, pp. 19169-19172
-
-
Baes, M.1
Castelein, H.2
Desmet, L.3
Declercq, P.E.4
-
28
-
-
0029067225
-
Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements
-
Keller H, Givel F, Perroud M, Wahli W. Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements. Mol Endocrinol 1995; 9: 794-804.
-
(1995)
Mol. Endocrinol.
, vol.9
, pp. 794-804
-
-
Keller, H.1
Givel, F.2
Perroud, M.3
Wahli, W.4
-
29
-
-
0343742625
-
Retinoid X receptor and peroxisome proliferator-activated receptor activate an estrogen responsive gene independent of the estrogen receptor
-
Nunez SB, Medin JA, Braissant O, Kemp L, Wahli W, Ozato K, Segars JH. Retinoid X receptor and peroxisome proliferator-activated receptor activate an estrogen responsive gene independent of the estrogen receptor. Mol Cell Endocrinol 1997; 127: 27-40.
-
(1997)
Mol. Cell Endocrinol.
, vol.127
, pp. 27-40
-
-
Nunez, S.B.1
Medin, J.A.2
Braissant, O.3
Kemp, L.4
Wahli, W.5
Ozato, K.6
Segars, J.H.7
-
30
-
-
0029417198
-
Thyroid hormone (T3) inhibits ciprofibrate-induced transcription of gene encoding β-oxidation enzymes: Crosstalk between peroxisome proliferator and T3 signaling pathways
-
Chu R, Madison LD, Lin Y, Kopp P, Rao MS, Jameson JL, Reddy JK. Thyroid hormone (T3) inhibits ciprofibrate-induced transcription of gene encoding β-oxidation enzymes: crosstalk between peroxisome proliferator and T3 signaling pathways. Proc Natl Acad Sci USA 1995; 92: 11593-7.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11593-11597
-
-
Chu, R.1
Madison, L.D.2
Lin, Y.3
Kopp, P.4
Rao, M.S.5
Jameson, J.L.6
Reddy, J.K.7
-
31
-
-
0029084409
-
Peroxisome proliferator-activated receptor mediates cross-talk with thyroid hormone receptor by competition for retinoid X receptor: Possible role of leucine zipper-like heptad repeat
-
Juge-Aubry CE, Gorla-Bajsczak A, Pernin A, Lemberger T, Wahli W, Burger AG, Meier CA. Peroxisome proliferator-activated receptor mediates cross-talk with thyroid hormone receptor by competition for retinoid X receptor: possible role of leucine zipper-like heptad repeat. J Biol Chem 1995; 270: 18117-22.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18117-18122
-
-
Juge-Aubry, C.E.1
Gorla-Bajsczak, A.2
Pernin, A.3
Lemberger, T.4
Wahli, W.5
Burger, A.G.6
Meier, C.A.7
-
32
-
-
0032871893
-
Nuclear receptor cofactors as chromatin remodelers
-
Lemon BD, Freedman LP. Nuclear receptor cofactors as chromatin remodelers. Curr Op Gen Dev 1999; 9: 499-504.
-
(1999)
Curr. Op. Gen. Dev.
, vol.9
, pp. 499-504
-
-
Lemon, B.D.1
Freedman, L.P.2
-
34
-
-
0030341454
-
Cloning and identification of mouse steroi receptor coactivator of peroxisome proliferator-activated receptor γ
-
Zhu Y, Qi C, Calandra C, Rao M, Reddy JK. Cloning and identification of mouse steroi receptor coactivator of peroxisome proliferator-activated receptor γ. Gene Expr 1996; 6: 185-95.
-
(1996)
Gene Expr.
, vol.6
, pp. 185-195
-
-
Zhu, Y.1
Qi, C.2
Calandra, C.3
Rao, M.4
Reddy, J.K.5
-
35
-
-
0037184960
-
SRC-1 and TIF2 control energy balance between white and brown adipose tissues
-
Picard F, Géhin M, Annicotte JS, Rocchi S, Champy MF, O'Malley Bw, Chambon P, Auwerx J. SRC-1 and TIF2 control energy balance between white and brown adipose tissues. Cell 2002; 111: 931-41.
-
(2002)
Cell
, vol.111
, pp. 931-941
-
-
Picard, F.1
Géhin, M.2
Annicotte, J.S.3
Rocchi, S.4
Champy, M.F.5
O'Malley, Bw.6
Chambon, P.7
Auwerx, J.8
-
37
-
-
0030570961
-
Transcription- A growing coactivator network
-
Janknecht R, Hunter T. Transcription- a growing coactivator network. Nature 1996; 383: 22-3.
-
(1996)
Nature
, vol.383
, pp. 22-23
-
-
Janknecht, R.1
Hunter, T.2
-
38
-
-
0343417089
-
The p300/CBP family: Integrating signals with transcription factors and chromatin
-
Shikama N, Lyon J, Lathangue NB. The p300/CBP family: integrating signals with transcription factors and chromatin. Trends Cell Biol 1997; 7: 230-6.
-
(1997)
Trends. Cell Biol.
, vol.7
, pp. 230-236
-
-
Shikama, N.1
Lyon, J.2
Lathangue, N.B.3
-
39
-
-
0036478904
-
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice
-
Yamauchi T, Oike Y, Kamon J, Waki H, Komeda K, Tsuchida A, Date Y, Li MX, Miki H, Akanuma Y. Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice. Nat Genet 2002; 30: 221-6.
-
(2002)
Nat. Genet.
, vol.30
, pp. 221-226
-
-
Yamauchi, T.1
Oike, Y.2
Kamon, J.3
Waki, H.4
Komeda, K.5
Tsuchida, A.6
Date, Y.7
Li, M.X.8
Miki, H.9
Akanuma, Y.10
-
40
-
-
1842295133
-
Peroxisome proliferator -activated receptors an retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators and corepressors
-
DiRenzo J, Soderstrom M, Kurokawa R, Ogliastro MH, Ricote M, Ingrey S, Horlein A, Rosenfeld MG, Glass CK. Peroxisome proliferator -activated receptors an retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators and corepressors. Mol Cell Biol 1997; 17: 2166-76.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 2166-2176
-
-
DiRenzo, J.1
Soderstrom, M.2
Kurokawa, R.3
Ogliastro, M.H.4
Ricote, M.5
Ingrey, S.6
Horlein, A.7
Rosenfeld, M.G.8
Glass, C.K.9
-
41
-
-
0030991152
-
Stoichiometric and steric principles governing repression by nuclear hormone receptors
-
Zamir I, Zhang J, Lazar MA. Stoichiometric and steric principles governing repression by nuclear hormone receptors. Genes Dev 1997; 11: 835-46.
-
(1997)
Genes Dev.
, vol.11
, pp. 835-846
-
-
Zamir, I.1
Zhang, J.2
Lazar, M.A.3
-
42
-
-
0038776380
-
Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ
-
Hu E, Kim JB, Sarraf P, Spiegelman BM. Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ. Science 1996; 274: 2100-3.
-
(1996)
Science
, vol.274
, pp. 2100-2103
-
-
Hu, E.1
Kim, J.B.2
Sarraf, P.3
Spiegelman, B.M.4
-
43
-
-
0029784760
-
The peroxisome proliferator-activated receptor a is a phosphoprotein: Regulation by insulin
-
Shalev A, Siegrist-Kaiser CA, Yen PM, Wahli W, Burger AG, Chin WW, Meier CA. The peroxisome proliferator-activated receptor a is a phosphoprotein: Regulation by insulin. Endocrinology 1996; 137: 4499-502.
-
(1996)
Endocrinology
, vol.137
, pp. 4499-4502
-
-
Shalev, A.1
Siegrist-Kaiser, C.A.2
Yen, P.M.3
Wahli, W.4
Burger, A.G.5
Chin, W.W.6
Meier, C.A.7
-
44
-
-
0030877565
-
Ligand- independent activation domain in the N terminus of peroxisome proliferator-activated receptor γ (PPAR γ)
-
Werman A, Hoolenberg A, Solanes G, Bjorbaek C, Vidal-Puig AJ, Flier JS. Ligand- independent activation domain in the N terminus of peroxisome proliferator-activated receptor γ (PPAR γ). J Biol Chem 1997; 272: 20230-5.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 20230-20235
-
-
Werman, A.1
Hoolenberg, A.2
Solanes, G.3
Bjorbaek, C.4
Vidal-Puig, A.J.5
Flier, J.S.6
-
45
-
-
0033537827
-
Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor alpha by phosphorilation of a ligand-independent trans-activating domain
-
Juge-Aubry CE, Hammar E, Siegrist-Kaiser CA, Pernin A, Takeshita A, Chin WW, Burger AG, Meier CA. Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor alpha by phosphorilation of a ligand-independent trans-activating domain. J Biol Chem 1999; 274: 10505-10.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10505-10510
-
-
Juge-Aubry, C.E.1
Hammar, E.2
Siegrist-Kaiser, C.A.3
Pernin, A.4
Takeshita, A.5
Chin, W.W.6
Burger, A.G.7
Meier, C.A.8
-
46
-
-
0029775642
-
Insulin-and mitogen-activated protein kinase-mediated phosphorilation and activation of peroxisome proliferator-activated receptor gamma
-
Zhang B, Bergerl J, Zhou G, Elbrech A, Biswas S, White-Carrington S, Szalkowski D, Moller DE. Insulin-and mitogen-activated protein kinase-mediated phosphorilation and activation of peroxisome proliferator-activated receptor gamma. J Biol Chem 1996; 271: 31771-4.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31771-31774
-
-
Zhang, B.1
Bergerl, J.2
Zhou, G.3
Elbrech, A.4
Biswas, S.5
White-Carrington, S.6
Szalkowski, D.7
Moller, D.E.8
-
47
-
-
0034530972
-
Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase A activators
-
Lazennec G, Canaple L, Saugy D, Wahli W. Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase A activators. Mol Endocrinol 2000; 14: 1962-75.
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1962-1975
-
-
Lazennec, G.1
Canaple, L.2
Saugy, D.3
Wahli, W.4
-
48
-
-
0031057517
-
Transcriptional activation by peroxisome proliferator-activated receptor g is inhibited by phosphorylation at a consensus mitogen activated protein kinase site
-
Adams M, Reginato MJ, Shao D, Lazar MA, Chatterjee VK. Transcriptional activation by peroxisome proliferator-activated receptor g is inhibited by phosphorylation at a consensus mitogen activated protein kinase site. J Biol Chem 1997; 271: 5128-32.
-
(1997)
J. Biol. Chem.
, vol.271
, pp. 5128-5132
-
-
Adams, M.1
Reginato, M.J.2
Shao, D.3
Lazar, M.A.4
Chatterjee, V.K.5
-
49
-
-
0030964085
-
Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase
-
Camp HS, Tafuri SR. Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase. J Biol Chem 1997; 272: 10811-6.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10811-10816
-
-
Camp, H.S.1
Tafuri, S.R.2
-
50
-
-
0032894240
-
c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-gammal and negatively regulates its transcriptional activity
-
Camp HS, Tafuri SR, Leff T. c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-gammal and negatively regulates its transcriptional activity. Endocrinology 1999; 140: 392-7.
-
(1999)
Endocrinology
, vol.140
, pp. 392-397
-
-
Camp, H.S.1
Tafuri, S.R.2
Leff, T.3
-
51
-
-
0034994075
-
Statin-induced inhibition of the Rho-signaling pathway activates PPARα and induces HDL apoA-1
-
Martin G, Duez H, Blanquart C, Berezowski V, Poulain P, Fruchart JC, Najib-Fruchart J, Glineur C, Staels B. Statin-induced inhibition of the Rho-signaling pathway activates PPARα and induces HDL apoA-1. J Clin Invest 2001; 107: 1423-32.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1423-1432
-
-
Martin, G.1
Duez, H.2
Blanquart, C.3
Berezowski, V.4
Poulain, P.5
Fruchart, J.C.6
Najib-Fruchart, J.7
Glineur, C.8
Staels, B.9
-
52
-
-
0036901003
-
Multisite phosphorylation provides sophisticated regulation of transcription factors
-
Holmberg CI, Tran SET, Eriksson JE, Sistonen L. Multisite phosphorylation provides sophisticated regulation of transcription factors. TiBS 2002; 27: 619-27.
-
(2002)
TiBS
, vol.27
, pp. 619-627
-
-
Holmberg, C.I.1
Tran, S.E.T.2
Eriksson, J.E.3
Sistonen, L.4
-
53
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
Desvergne B, Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocrine Rev 1999; 20: 649-88.
-
(1999)
Endocrine Rev.
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
54
-
-
0036813001
-
Peroxisome proliferator-activated receptors: Lipid binding proteins controling gene expression
-
van Bilsen M, van der Vusse GJ, Gilde AJ, Lindhout M, van Der Lee KA. Peroxisome proliferator-activated receptors: lipid binding proteins controling gene expression. Mol Cell Biochem 2002; 239: 131-8.
-
(2002)
Mol. Cell Biochem.
, vol.239
, pp. 131-138
-
-
van Bilsen, M.1
van der Vusse, G.J.2
Gilde, A.J.3
Lindhout, M.4
van Der Lee, K.A.5
-
55
-
-
0036813345
-
Critical steps in cellular fatty acid uptake and utilization
-
van der Vusse GJ, Van Bilsen M, Glatz JF, Hasselbaink DM, Luiken JJ. Critical steps in cellular fatty acid uptake and utilization. Mol Cell Biochem 2002; 239: 9-15.
-
(2002)
Mol. Cell Biochem.
, vol.239
, pp. 9-15
-
-
van der Vusse, G.J.1
Van Bilsen, M.2
Glatz, J.F.3
Hasselbaink, D.M.4
Luiken, J.J.5
-
56
-
-
0026551309
-
Fatty acids activate a chimera of the clofibric activated receptor and the glucocorticoid receptor
-
Gottlicher M, Widmark E, Li Q, Gustafisson JA. Fatty acids activate a chimera of the clofibric activated receptor and the glucocorticoid receptor. Proc Natl Acad Sci USA 1992; 89: 4653-7.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4653-4657
-
-
Gottlicher, M.1
Widmark, E.2
Li, Q.3
Gustafisson, J.A.4
-
57
-
-
0006132932
-
Fatty acids and eicosanoids regulate gene expression trough direct interactions with peroxisome proliferator-activated receptors α and γ
-
Kliewer SA, Sundseth SS, Jones SA. Fatty acids and eicosanoids regulate gene expression trough direct interactions with peroxisome proliferator-activated receptors α and γ. Proc Natl Acad Sci USA 1997; 94: 4318-23.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4318-4323
-
-
Kliewer, S.A.1
Sundseth, S.S.2
Jones, S.A.3
-
58
-
-
0035897696
-
Expert pAnel on detection e, and treatment of high blood cholesterol in adults. Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III)
-
Expert pAnel on detection e, and treatment of high blood cholesterol in adults. Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). JAMA 2001; 285: 2486-97.
-
(2001)
JAMA
, vol.285
, pp. 2486-2497
-
-
-
59
-
-
0026040907
-
Development of muscle insulin resistance after liver insulin resistance in high fat-fed rats
-
Kraegen EW, Clark PW, Jenkins AB, Daley EA, Chisholm DJ, Storlien EH. Development of muscle insulin resistance after liver insulin resistance in high fat-fed rats. Diabetes 1991; 40: 1397-403.
-
(1991)
Diabetes
, vol.40
, pp. 1397-1403
-
-
Kraegen, E.W.1
Clark, P.W.2
Jenkins, A.B.3
Daley, E.A.4
Chisholm, D.J.5
Storlien, E.H.6
-
60
-
-
0023240831
-
Fish oil prevents insulin resistance induced by high fat feeding in rats
-
Storlein LIL Kraegen EW, Chisholm DJ, Ford GL, Bruce DG, Pascoe WS. Fish oil prevents insulin resistance induced by high fat feeding in rats. Science 1987; 237: 885-8.
-
(1987)
Science
, vol.237
, pp. 885-888
-
-
Storlein, L.I.L.1
Kraegen, E.W.2
Chisholm, D.J.3
Ford, G.L.4
Bruce, D.G.5
Pascoe, W.S.6
-
61
-
-
0027169113
-
Polyunsaturated fatty acids inhibit S14 gene transcription in rat liver and cultured hepatocytes
-
Jump DB, Clarke SD, MacDougald OA, Thelen A. Polyunsaturated fatty acids inhibit S14 gene transcription in rat liver and cultured hepatocytes. Proc Natl Acad Sci USA 1993; 90: 8454-8.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8454-8458
-
-
Jump, D.B.1
Clarke, S.D.2
MacDougald, O.A.3
Thelen, A.4
-
62
-
-
0028214097
-
Coordinate regulation of glycolytic ad lipogenic gene expression by polyunsaturated fatty acids
-
Jump DB, Clarke SD, Thelen A, Liimatta M. Coordinate regulation of glycolytic ad lipogenic gene expression by polyunsaturated fatty acids. J Lipid Res 1994; 35: 1076-84.
-
(1994)
J. Lipid. Res.
, vol.35
, pp. 1076-1084
-
-
Jump, D.B.1
Clarke, S.D.2
Thelen, A.3
Liimatta, M.4
-
63
-
-
0029661982
-
The PPARα - Leukotriene B4 pathway to inflammation control
-
Devchand PR, Keller H, Peters JM, Vazquez M, Gonzalez FJ, Wahli W. The PPARα - leukotriene B4 pathway to inflammation control. Nature 1996;384: 39-43.
-
(1996)
Nature
, vol.384
, pp. 39-43
-
-
Devchand, P.R.1
Keller, H.2
Peters, J.M.3
Vazquez, M.4
Gonzalez, F.J.5
Wahli, W.6
-
64
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor g and promotes adipocyte differentiation
-
Kliewer SA, Lehnard JM, Willson TM, Patel I, Morris DC, Lehman JM. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor g and promotes adipocyte differentiation. Cell 1995; 83: 813-9.
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
Lehnard, J.M.2
Willson, T.M.3
Patel, I.4
Morris, D.C.5
Lehman, J.M.6
-
65
-
-
0028802627
-
Differential activation of peroxisome proliferator-activated receptors by eicosanoids
-
Yu K, Bayona W, Kallen CB, Harding HP, Ravera CP, McMahon G, Brown M, Lazar MA. Differential activation of peroxisome proliferator-activated receptors by eicosanoids. J Biol Chem 1995; 270: 23975-83.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23975-23983
-
-
Yu, K.1
Bayona, W.2
Kallen, C.B.3
Harding, H.P.4
Ravera, C.P.5
McMahon, G.6
Brown, M.7
Lazar, M.A.8
-
66
-
-
0027983920
-
Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
-
Nolan JJ, Ludvik B, Beerdsen P, Joyce M, Olefsky J. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med 1994; 331: 1188-93.
-
(1994)
N. Engl. J. Med.
, vol.331
, pp. 1188-1193
-
-
Nolan, J.J.1
Ludvik, B.2
Beerdsen, P.3
Joyce, M.4
Olefsky, J.5
-
67
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand por peroxisome proliferator-activated receptor γ (PPAR γ)
-
Lehman J, Moore LB, Smith-Oliver TA, Wilkinson WO, Willson TM, Kliewer SA. An antidiabetic thiazolidinedione is a high affinity ligand por peroxisome proliferator-activated receptor γ (PPAR γ). J Biol Chem 1995; 270: 12953-6.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953-12956
-
-
Lehman, J.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkinson, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
68
-
-
0030747895
-
Tissue distribution and quantification of the expression of mRNAs of peroxisoine proliterator-activated receptors and liver X receptor-a in humans: No alteration in adipose tissue of obese and NIDDM patients
-
Auboeuf D. Rieusset J, Fajas L, Valier P, Frering V, Riou JP, Staels B, Quwerx J. Laville M, Vidal H. Tissue distribution and quantification of the expression of mRNAs of peroxisoine proliterator-activated receptors and liver X receptor-a in humans: no alteration in adipose tissue of obese and NIDDM patients. Diabetes 1997; 48: 1319-27.
-
(1997)
Diabetes
, vol.48
, pp. 1319-1327
-
-
Auboeuf, D.1
Rieusset, J.2
Fajas, L.3
Valier, P.4
Frering, V.5
Riou, J.P.6
Staels, B.7
Quwerx, J.8
Laville, M.9
Vidal, H.10
-
69
-
-
0034842626
-
The peroxisome proliferator-activated receptor a regulates amino acid metabolism
-
Kersten S, Mandard S, Escher P, Gonzalez FJ, Taluri S, Desvergne B, Wahli W. The peroxisome proliferator-activated receptor a regulates amino acid metabolism. FASEB J 2001; 15: 1971-8.
-
(2001)
FASEB J.
, vol.15
, pp. 1971-1978
-
-
Kersten, S.1
Mandard, S.2
Escher, P.3
Gonzalez, F.J.4
Taluri, S.5
Desvergne, B.6
Wahli, W.7
-
70
-
-
0032699670
-
Peroxisome proliferator-activated receptor a mediates the adaptive response to fasting
-
Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Peroxisome proliferator-activated receptor a mediates the adaptive response to fasting. J Clin Invest 1999; 103: 1489-98.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1489-1498
-
-
Kersten, S.1
Seydoux, J.2
Peters, J.M.3
Gonzalez, F.J.4
Desvergne, B.5
Wahli, W.6
-
71
-
-
0033594980
-
A critical role for the peroxisome proliferator-activated receptor α (PPAR α) in the cellular Fasting response: The PPAR α-null mouse as a model of fatty acid oxidation disorders
-
Leone TC, Weinheimer CJ, Kelly DP. A critical role for the peroxisome proliferator-activated receptor α (PPAR α) in the cellular Fasting response: The PPAR α-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci USA 1999; 96: 7473-8.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7473-7478
-
-
Leone, T.C.1
Weinheimer, C.J.2
Kelly, D.P.3
-
72
-
-
0030060358
-
Expression of the peroxisome proliferator-activated receptor α gene is stimulated by stress and follows a diurnal rythm
-
Lernberger T, Saladin R, Vazquez M, Assimacopoulos F, Staels B, Desvergne B, Wahli W, Auwerx J. Expression of the peroxisome proliferator-activated receptor α gene is stimulated by stress and follows a diurnal rythm. J Biol Chem 1996; 271: 1764-9.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1764-1769
-
-
Lernberger, T.1
Saladin, R.2
Vazquez, M.3
Assimacopoulos, F.4
Staels, B.5
Desvergne, B.6
Wahli, W.7
Auwerx, J.8
-
73
-
-
0032491614
-
Peroxisome proliferator-activated receptor α-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis
-
Costet P, Legendre C, More J, Edgar A, Galtier P, Pinedu T. Peroxisome proliferator-activated receptor α-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis. J Biol Chem 1998; 273: 29577-85.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29577-29585
-
-
Costet, P.1
Legendre, C.2
More, J.3
Edgar, A.4
Galtier, P.5
Pinedu, T.6
-
74
-
-
0032530765
-
A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator-activated receptor α -deficient mice
-
Djouadi F, Weinheimer CJ, Saffitz JE, Pitchford C, Bastin J, Gonzalez FJ, Kelly DP. A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator-activated receptor α-deficient mice. J Clin Invest 1998; 102: 1083-91.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1083-1091
-
-
Djouadi, F.1
Weinheimer, C.J.2
Saffitz, J.E.3
Pitchford, C.4
Bastin, J.5
Gonzalez, F.J.6
Kelly, D.P.7
-
75
-
-
0035653490
-
PPARa-null mice are protected from high-fat diet induced insulin resistance
-
Guerre-Millo M, Rouault C, Poulain P, André J, Poitout V, Peters JM, Gonzalez FJ, Fruchart JC, Reach G, Staels B. PPARa-null mice are protected from high-fat diet induced insulin resistance. Diabetes 2001; 50: 2809-14.
-
(2001)
Diabetes
, vol.50
, pp. 2809-2814
-
-
Guerre-Millo, M.1
Rouault, C.2
Poulain, P.3
André, J.4
Poitout, V.5
Peters, J.M.6
Gonzalez, F.J.7
Fruchart, J.C.8
Reach, G.9
Staels, B.10
-
76
-
-
0037135623
-
Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) a Knock-out mice. Evidence for compensatory regulation by PPARd
-
Muoio DM, MacLean PS, Lang DB, Li S, Hournard JA, Way JM, Winegar DA, Corton JC, Dohm GL, Kraus WE. Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) a Knock-out mice. Evidence for compensatory regulation by PPARd. J Biol Chern 2002; 277: 26089-97.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 26089-26097
-
-
Muoio, D.M.1
MacLean, P.S.2
Lang, D.B.3
Li, S.4
Hournard, J.A.5
Way, J.M.6
Winegar, D.A.7
Corton, J.C.8
Dohm, G.L.9
Kraus, W.E.10
-
77
-
-
0028988487
-
PPAR γ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
-
Tontonoz P, Hu E, Devine J, Beale EG, Spiegelman BM. PPAR γ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol 1995; 15: 351-7.
-
(1995)
Mol. Cell Biol.
, vol.15
, pp. 351-357
-
-
Tontonoz, P.1
Hu, E.2
Devine, J.3
Beale, E.G.4
Spiegelman, B.M.5
-
78
-
-
0034453225
-
Cross-talk between Fatty acid cholesterol metabolism mediated by liver X receptor-alpha
-
Tobin KA, Steineger HH. Alberti S, Spydevold O, Ausverx J, Gustafsson JA, Nebb Hl. Cross-talk between Fatty acid cholesterol metabolism mediated by liver X receptor-alpha. Mol Endocrinol 2000; 14: 741-52.
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 741-752
-
-
Tobin, K.A.1
Steineger, H.H.2
Alberti, S.3
Spydevold, O.4
Ausverx, J.5
Gustafsson, J.A.6
Nebb, H.I.7
-
79
-
-
0029143455
-
Effects of different phenotypes of hyperlipoproteinemia and of treatment with fibric acid derivatives on the rates of cholesterol 7 alpha-hydroxylation in humans
-
Bertolotti M, Concari M, Loria P, Abate N, Pinetti A, Guicciardi ME, Carulli N. Effects of different phenotypes of hyperlipoproteinemia and of treatment with fibric acid derivatives on the rates of cholesterol 7 alpha-hydroxylation in humans. Arterioscler Thromb Vasc Biol 1995; 15: 1064-9.
-
(1995)
Arterioscler. Thromb. Vasc. Biol.
, vol.15
, pp. 1064-1069
-
-
Bertolotti, M.1
Concari, M.2
Loria, P.3
Abate, N.4
Pinetti, A.5
Guicciardi, M.E.6
Carulli, N.7
-
80
-
-
0033999108
-
Peroxisome proliferator-activated receptor alpha (PPAR alpha) and agonist inhibit cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription
-
Marrapodi M, Chiang JY. Peroxisome proliferator-activated receptor alpha (PPAR alpha) and agonist inhibit cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription. J Lipid Res 2000; 41: 514-20.
-
(2000)
J. Lipid. Res.
, vol.41
, pp. 514-520
-
-
Marrapodi, M.1
Chiang, J.Y.2
-
81
-
-
0034331437
-
The effect of peroxisome-proliferator-activated receptor-α on the activity of the cholesterol 7α-hydroxilase gene
-
Patel DD, Knight BE, Soutar AK, Gibbons GF, Wade DP. The effect of peroxisome-proliferator-activated receptor-α on the activity of the cholesterol 7α-hydroxilase gene. Biochem J 2000; 351: 747-53.
-
(2000)
Biochem. J.
, vol.351
, pp. 747-753
-
-
Patel, D.D.1
Knight, B.E.2
Soutar, A.K.3
Gibbons, G.F.4
Wade, D.P.5
-
82
-
-
0034666324
-
The peroxisomne proliferator-activated receptor alpha (PPARalpha) regulates bile acid biosynthesis
-
Hunt MC, Yang YZ, Eggertsen G, Cameheim CM, Gafvels M, Einarsson C, Alexson SE. The peroxisomne proliferator-activated receptor alpha (PPARalpha) regulates bile acid biosynthesis. J Biol Chem 2000; 275: 28947-53.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28947-28953
-
-
Hunt, M.C.1
Yang, Y.Z.2
Eggertsen, G.3
Cameheim, C.M.4
Gafvels, M.5
Einarsson, C.6
Alexson, S.E.7
-
83
-
-
0032169919
-
Fenofibrate modifies transaminase gene expression via a peroxisome proliferator activated receptor α-dependent pathway
-
Edgar AD, Tomkiesvicz C, Costet P, Legendre C, Aggerbeck M, Bouguet J, Staels B, Guyomard C, Pineau T, Barouki R. Fenofibrate modifies transaminase gene expression via a peroxisome proliferator activated receptor α-dependent pathway. Toxicol Lett 1998; 98: 13-23.
-
(1998)
Toxicol. Lett.
, vol.98
, pp. 13-23
-
-
Edgar, A.D.1
Tomkiesvicz, C.2
Costet, P.3
Legendre, C.4
Aggerbeck, M.5
Bouguet, J.6
Staels, B.7
Guyomard, C.8
Pineau, T.9
Barouki, R.10
-
84
-
-
0033527569
-
Peroxisome proliferator activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1
-
Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ, Fruchart JC, Tedgui A, Haegeman G, Staels B. Peroxisome proliferator activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J Biol Chem 1999; 274: 32048-54.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32048-32054
-
-
Delerive, P.1
De Bosscher, K.2
Besnard, S.3
Vanden Berghe, W.4
Peters, J.M.5
Gonzalez, F.J.6
Fruchart, J.C.7
Tedgui, A.8
Haegeman, G.9
Staels, B.10
-
85
-
-
0033594810
-
PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells
-
Marx N, Sukhova GK, Collins P, Libby J, Plutzky J. PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation 1999; 99: 3125-31.
-
(1999)
Circulation
, vol.99
, pp. 3125-3131
-
-
Marx, N.1
Sukhova, G.K.2
Collins, P.3
Libby, J.4
Plutzky, J.5
-
86
-
-
0034711678
-
Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator -activated receptor-gamma activators
-
Pasceri V, Wu HD, Willerson JT, Yeh ET. Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator -activated receptor-gamma activators. Circulation 2000;101: 235-8.
-
(2000)
Circulation
, vol.101
, pp. 235-238
-
-
Pasceri, V.1
Wu, H.D.2
Willerson, J.T.3
Yeh, E.T.4
-
87
-
-
0034801882
-
Rat PPARs: Quantitative analysis in adult rat tissues and regulation in fasting and refeeding
-
Escher P, Braissant O, Basu-Moclak S, Michalik L, Wahli W, Desvergne B. Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding. Endocrinology 2001; 142: 4195-202.
-
(2001)
Endocrinology
, vol.142
, pp. 4195-4202
-
-
Escher, P.1
Braissant, O.2
Basu-Moclak, S.3
Michalik, L.4
Wahli, W.5
Desvergne, B.6
-
88
-
-
0037453718
-
Peroxisome-prolifierator activated receptor 8 activates fat metabolism to prevent obesity
-
Wang Y-X, Lee C-H, Tien S, Yu RT, Ham J, Kang H, Evans RM. Peroxisome-prolifierator activated receptor 8 activates fat metabolism to prevent obesity. Cell 2003; 113: 159-70.
-
(2003)
Cell
, vol.113
, pp. 159-170
-
-
Wang, Y.-X.1
Lee, C.-H.2
Tien, S.3
Yu, R.T.4
Ham, J.5
Kang, H.6
Evans, R.M.7
-
89
-
-
0035942162
-
A selective peroxisome proliferator-activated receptor 6 agonist promotes reverse cholesterol transport
-
Oliver WR, Shenk JL, Snaith MR, Russell CS, Pluket KD, Bodkin NL, Lewis MC, Winegar DA, Sznaidman ME, Lambert MH, Xu HE, Sternbach DD, Kliewer SA, Hnsen BC, Willson TM. A selective peroxisome proliferator-activated receptor 6 agonist promotes reverse cholesterol transport. Proc Natl Acad Sci USA 2001; 98: 5306-11.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 5306-5311
-
-
Oliver, W.R.1
Shenk, J.L.2
Snaith, M.R.3
Russell, C.S.4
Pluket, K.D.5
Bodkin, N.L.6
Lewis, M.C.7
Winegar, D.A.8
Sznaidman, M.E.9
Lambert, M.H.10
Xu, H.E.11
Sternbach, D.D.12
Kliewer, S.A.13
Hnsen, B.C.14
Willson, T.M.15
-
91
-
-
0037459358
-
Peroxisome proliferator-activated receptor (PPAR) alpha and PPAR beta/delta, but not PPAR gamma, modulate the expression of genes involved in cardiac lipid metabolism
-
ahead of print
-
Gilde AJ, Van Der Lee KA, Willernsen PH, Chinetti G, Van der Leij FR, Vand der Vusse GJ, Staels B, Van Bilsen M. Peroxisome proliferator-activated receptor (PPAR) alpha and PPAR beta/delta, but not PPAR gamma, modulate the expression of genes involved in cardiac lipid metabolism. Cire Res 2003; ahead of print.
-
(2003)
Circ. Res.
-
-
Gilde, A.J.1
Van Der Lee, K.A.2
Willernsen, P.H.3
Chinetti, G.4
Van der Leij, F.R.5
Vand der Vusse, G.J.6
Staels, B.7
Van Bilsen, M.8
-
92
-
-
0029102676
-
Structural organization of mouse peroxisome proliferator-activated receptor γ (mPPAR γ) gene: Alternative promoter use and different splicing yield two mPPAR γ isoforms
-
Zhu Y, Qi C, Korenberg JR, Chen XN, Noya D, Rao MS, Reddy JK. Structural organization of mouse peroxisome proliferator-activated receptor γ (mPPAR γ) gene: alternative promoter use and different splicing yield two mPPAR γ isoforms. Proc Natl Acad Sci USA 1995; 92: 7921-5.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7921-7925
-
-
Zhu, Y.1
Qi, C.2
Korenberg, J.R.3
Chen, X.N.4
Noya, D.5
Rao, M.S.6
Reddy, J.K.7
-
93
-
-
0032582349
-
PPAR γ 3 mRNA: A distinct PPAR γ mRNA subtype transcribed from an independent promoter
-
Fajas L, Fruchart JC, Auwerx J. PPAR γ 3 mRNA: a distinct PPAR γ mRNA subtype transcribed from an independent promoter. FEBS left 1998; 438: 55-60.
-
(1998)
FEBS Lett.
, vol.438
, pp. 55-60
-
-
Fajas, L.1
Fruchart, J.C.2
Auwerx, J.3
-
94
-
-
0030047806
-
Differential expression of peroxisome proliferator-activated receptors: Tissue distribution of PPAR -α, -β, and -γ in the adult rat
-
Braissant O, Foufelle F, Scotto C, Sauca M, Wahli W. Differential expression of peroxisome proliferator-activated receptors: tissue distribution of PPAR -α, -β, and -γ in the adult rat. Endocrinology, 1996; 137: 354-66.
-
(1996)
Endocrinology
, vol.137
, pp. 354-366
-
-
Braissant, O.1
Foufelle, F.2
Scotto, C.3
Sauca, M.4
Wahli, W.5
-
95
-
-
0030977450
-
Peroxisome prolifierator activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids
-
Vidal-Puig AJ, Considine RV, Jimenez-Linan M, Werman A, Pories WJ, Caro JF, Flier JS. Peroxisome prolifierator activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J Clin Invest 1997; 99: 2416-22.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2416-2422
-
-
Vidal-Puig, A.J.1
Considine, R.V.2
Jimenez-Linan, M.3
Werman, A.4
Pories, W.J.5
Caro, J.F.6
Flier, J.S.7
-
96
-
-
0030972203
-
TNFα-mediated inhibition and reversal adipocyte differentiation is accompanied by suppressed expression of PPAR γ without effects on Pref-1 expression
-
Xing H, Northrop JP, Grove JR, Kilpatrick KE, Su JL, Ringold GM. TNFα-mediated inhibition and reversal adipocyte differentiation is accompanied by suppressed expression of PPAR γ without effects on Pref-1 expression. Endocrinology 1997; 138: 2776-83.
-
(1997)
Endocrinology
, vol.138
, pp. 2776-2783
-
-
Xing, H.1
Northrop, J.P.2
Grove, J.R.3
Kilpatrick, K.E.4
Su, J.L.5
Ringold, G.M.6
-
97
-
-
0028909362
-
Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferator-related receptors
-
Amri EZ,. Bonino f. Ailhaud G, Abumrad NA, Grimaldi PA. Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferator-related receptors. J Biol Chem 1995; 270: 2367-71.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2367-2371
-
-
Amri, E.Z.1
Bonino, F.2
Ailhaud, G.3
Abumrad, N.A.4
Grimaldi, P.A.5
-
98
-
-
0030000088
-
Regulation of PPAR γ gene expression by nutrition and obesity in rodents
-
Vidal-Puig A. Jimenez-Linan M, Lowell BB, Hamann A, Hu E, Spiegelman B. Flier JS. Moller DE. Regulation of PPAR γ gene expression by nutrition and obesity in rodents. J Clin Invest 1996: 97; 2553-61.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2553-2561
-
-
Vidal-Puig, A.1
Jimenez-Linan, M.2
Lowell, B.B.3
Hamann, A.4
Hu, E.5
Spiegelman, B.6
Flier, J.S.7
Moller, D.E.8
-
99
-
-
0033213637
-
PPAR γ is required for placental. cardiac and adipose tissue development
-
Barak Y. Nelson MC. Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR. Koder A. Evans RM. PPAR γ is required for placental. cardiac and adipose tissue development. Molecular Cell 1999; 4: 585-95.
-
(1999)
Molecular Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Jones, Y.Z.4
Ruiz-Lozano, P.5
Chien, K.R.6
Koder, A.7
Evans, R.M.8
-
100
-
-
0034713444
-
Roles of PPARs in health in disease
-
Kersten S. Desvergne B, Wahli W. Roles of PPARs in health in disease. Nature 2000: 405: 421-4.
-
(2000)
Nature
, vol.405
, pp. 421-424
-
-
Kersten, S.1
Desvergne, B.2
Wahli, W.3
-
101
-
-
0033213631
-
PPAR γ is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen ED, Sarraf P. Troy AE, Bradwin G, Moore K, Milstone DS, Spiegelman BM, Mortensen RM. PPAR γ is required for the differentiation of adipose tissue in vivo and in vitro. Molecular Cell 1999; 4: 611-7.
-
(1999)
Molecular Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
Bradwin, G.4
Moore, K.5
Milstone, D.S.6
Spiegelman, B.M.7
Mortensen, R.M.8
-
102
-
-
0034767452
-
Exposure to an obesity-inducing diet early affects the pattern of expression of peroxisome proliferator, retinoic acid, ad triiodothyronine nuclear receptors in the rat
-
Redonnet A, Groubet R, Noel-Suberville C, Bonilla S, Martinez A, Higueret P. Exposure to an obesity-inducing diet early affects the pattern of expression of peroxisome proliferator, retinoic acid, ad triiodothyronine nuclear receptors in the rat. Metabolism 2001; 50: 1161-7.
-
(2001)
Metabolism
, vol.50
, pp. 1161-1167
-
-
Redonnet, A.1
Groubet, R.2
Noel-Suberville, C.3
Bonilla, S.4
Martinez, A.5
Higueret, P.6
-
103
-
-
0037066589
-
Peroxisome proliferator activated receptors and obesity
-
Kersten S. Peroxisome proliferator activated receptors and obesity. Eur J Pharmacol 2002; 440: 223-34.
-
(2002)
Eur. J. Pharmacol.
, vol.440
, pp. 223-234
-
-
Kersten, S.1
-
104
-
-
0033212964
-
PPAR γ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Komeda K, Satoh S, Ryosuke N, Ishii C, Sugiyama T, Eto K, Tsubamoto Y, Okuno A, Murakami K, Sekihara H, Hasegawa G, Naito M. Toyoshima Y, Tanaka S, Shiota K, Kitamura T, Fujita R. Ezaki O, Aizawa S, Nagai R, Tobe K, Kimura S, Kadowaki T. PPAR γ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Molecular Cell 1999; 4: 597-609.
-
(1999)
Molecular Cell
, vol.4
, pp. 597-609
-
-
Kubota, N.1
Terauchi, Y.2
Miki, H.3
Tamemoto, H.4
Yamauchi, T.5
Komeda, K.6
Satoh, S.7
Ryosuke, N.8
Ishii, C.9
Sugiyama, T.10
Eto, K.11
Tsubamoto, Y.12
Okuno, A.13
Murakami, K.14
Sekihara, H.15
Hasegawa, G.16
Naito, M.17
Toyoshima, Y.18
Tanaka, S.19
Shiota, K.20
Kitamura, T.21
Fujita, R.22
Ezaki, O.23
Aizawa, S.24
Nagai, R.25
Tobe, K.26
Kimura, S.27
Kadowaki, T.28
more..
-
105
-
-
0033973843
-
Improved insulin-sensitivity in mice heterozygous for PPAR γ deficiency
-
Miles PD. Barak Y, He W, Evans RM, Olefsky JM. Improved insulin-sensitivity in mice heterozygous for PPAR γ deficiency. J Clin Invest 2000; 105: 287-92.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 287-292
-
-
Miles, P.D.1
Barak, Y.2
He, W.3
Evans, R.M.4
Olefsky, J.M.5
-
106
-
-
0031595923
-
A Pro 12 Ala substitution in PPAR γ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
Deeb SS, Fajas L, Nemoto M, Pihlajamaki J, Mykhanen L, Kuusisto J, Laakso M, Fujimoto W, Auwerx J. A Pro 12 Ala substitution in PPAR γ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet 1998; 20: 284-7.
-
(1998)
Nat. Genet.
, vol.20
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
Pihlajamaki, J.4
Mykhanen, L.5
Kuusisto, J.6
Laakso, M.7
Fujimoto, W.8
Auwerx, J.9
-
107
-
-
0034745185
-
12 - Ala substitution in PPAR- γ is associated with resistance to development of diabetes in the general population
-
12 - Ala substitution in PPAR- γ is associated with resistance to development of diabetes in the general population. Diabetes 2001; 50: 891-4.
-
(2001)
Diabetes
, vol.50
, pp. 891-894
-
-
Mori, H.1
Ikegami, H.2
Kawaguchi, Y.3
Seino, S.4
Yokoi, N.5
Takeda, J.6
Inoue, I.7
Seino, Y.8
Yasuda, K.9
Hanafusa, T.10
Yamagata, K.11
Awata, T.12
Kadowaki, T.13
Hara, K.14
Yamada, N.15
Gotoda, R.16
Iwasaki, N.17
Iwamoto, Y.18
Sanke, T.19
Nanjo, K.20
Oka, Y.21
Matsutani, A.22
Maeda, E.23
Kasuga, M.24
more..
-
108
-
-
0032189782
-
Obesity asociated with the mutation in a genetic regulator of adipocyte differentiation
-
Ristow M, Muller-Wieland D, Pfeifer A, Krone W, Kahn R. Obesity asociated with the mutation in a genetic regulator of adipocyte differentiation. N Engl J Med 1998; 339: 953-9.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 953-959
-
-
Ristow, M.1
Muller-Wieland, D.2
Pfeifer, A.3
Krone, W.4
Kahn, R.5
-
109
-
-
0033515761
-
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
-
Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999; 257: 79-83.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.257
, pp. 79-83
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
Takahashi, M.4
Maeda, K.5
Miyagawa, J.6
Hotta, K.7
Shimomura, I.8
Nakamura, T.9
Miyaoka, K.10
Kuriyama, H.11
Nishida, M.12
Yamashita, S.13
Okubo, K.14
Matsubara, K.15
Muraguchi, M.16
Ohmoto, Y.17
Funahashi, T.18
Matsuzawa, Y.19
-
110
-
-
0037031267
-
Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus
-
Haffner SM, Greenberg WM, Weston H, Chen K, Williams MI. Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus. Circulation 2002; 106: 679-84.
-
(2002)
Circulation
, vol.106
, pp. 679-684
-
-
Haffner, S.M.1
Greenberg, W.M.2
Weston, H.3
Chen, K.4
Williams, M.I.5
-
111
-
-
17544382289
-
AdipoQ is a novel adipose-specific gene dysregulated in obesity
-
Hu E, Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 1996; 271: 10697-703.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10697-10703
-
-
Hu, E.1
Liang, P.2
Spiegelman, B.M.3
-
112
-
-
0028787490
-
A novel serum protein similar to C1q, produced exclusively in adipocytes
-
Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 1995; 270: 26746-9.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26746-26749
-
-
Scherer, P.E.1
Williams, S.2
Fogliano, M.3
Baldini, G.4
Lodish, H.F.5
-
113
-
-
0032587268
-
Rosiglitazone (BRL49653), a PPAR g selective agonist, causes peroxisome proliferator like liver effects in mice
-
Edvardsson U, Bergstrom M, Alexanderssin M, Bamberg K, Ljung B, Dahllof B. Rosiglitazone (BRL49653), a PPAR g selective agonist, causes peroxisome proliferator like liver effects in mice. J Lipid Res 1999; 40: 1177-84.
-
(1999)
J. Lipid. Res.
, vol.40
, pp. 1177-1184
-
-
Edvardsson, U.1
Bergstrom, M.2
Alexanderssin, M.3
Bamberg, K.4
Ljung, B.5
Dahllof, B.6
-
114
-
-
0032557156
-
Physiological properties and functions of intracellular fatty acid binding proteins
-
Coe NR, Bernlohr DA. Physiological properties and functions of intracellular fatty acid binding proteins. Biochim Biophys Acia 1998; 1391: 287-306.
-
(1998)
Biochim. Biophys. Acia
, vol.1391
, pp. 287-306
-
-
Coe, N.R.1
Bernlohr, D.A.2
-
115
-
-
0033695790
-
Up-regulation of peroxisome proliferator-activated receptors (PPAR-α) and PPAR-γ messenger ribonucleic acid expression in the liver in murine obesity: Troglitazone induces expression of PPAR-γ-responsive adipose tissue-specific genes in the liver of obese diabetic mice
-
Memon RA, Tecott LH, Nonogaki K, Beigneux A, Moser AH, Grunfeld C, Feingold KR. Up-regulation of peroxisome proliferator-activated receptors (PPAR-α) and PPAR-γ messenger ribonucleic acid expression in the liver in murine obesity: Troglitazone induces expression of PPAR-γ-responsive adipose tissue-specific genes in the liver of obese diabetic mice. Endocrinology 2000; 141: 4021-31.
-
(2000)
Endocrinology
, vol.141
, pp. 4021-4031
-
-
Memon, R.A.1
Tecott, L.H.2
Nonogaki, K.3
Beigneux, A.4
Moser, A.H.5
Grunfeld, C.6
Feingold, K.R.7
-
117
-
-
0033605261
-
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion
-
Chavin KD, Yang S, Lin HZ, Chatham J, Chacko VP, Hoek JB, Walajtys-Rode E, Rashid A, Chen CH, Huang CC, Wu TC, Lane MD, Diehl AM. Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. J Biol Chem 1999; 274: 5692-700.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5692-5700
-
-
Chavin, K.D.1
Yang, S.2
Lin, H.Z.3
Chatham, J.4
Chacko, V.P.5
Hoek, J.B.6
Walajtys-Rode, E.7
Rashid, A.8
Chen, C.H.9
Huang, C.C.10
Wu, T.C.11
Lane, M.D.12
Diehl, A.M.13
-
118
-
-
0032854610
-
Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm
-
Abumrad NA, Coburn C, Ibrahimi A. Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm. Biochim Biophys Acta 1999; 1441: 4-13.
-
(1999)
Biochim. Biophys. Acta
, vol.1441
, pp. 4-13
-
-
Abumrad, N.A.1
Coburn, C.2
Ibrahimi, A.3
-
119
-
-
0033516477
-
A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism
-
Febbraio M, Abumrad NA, Hajjar DP, Sharma K, Cheng W, Pearce SFA, Silverstein RL. A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J Biol Chem 1999; 274: 19055-62.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19055-19062
-
-
Febbraio, M.1
Abumrad, N.A.2
Hajjar, D.P.3
Sharma, K.4
Cheng, W.5
Pearce, S.F.A.6
Silverstein, R.L.7
-
120
-
-
0032958470
-
Identification of CD36 (FAT) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
-
Aitman TJ, Glazier AM, Wallace CA, Cooper LD, Norsworthy PJ, Wahid FN, Al-Mahali KM, Trembling PM, Mann CJ, Shoulders CC, Graf D, St Lezin E, Kurtz TW, Kren V, Prevanec M, Ibrahimi A, Abumrad NA, Stanton LW, Scott J. Identification of CD36 (FAT) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat Genet 1999; 21: 76-83.
-
(1999)
Nat. Genet.
, vol.21
, pp. 76-83
-
-
Aitman, T.J.1
Glazier, A.M.2
Wallace, C.A.3
Cooper, L.D.4
Norsworthy, P.J.5
Wahid, F.N.6
Al-Mahali, K.M.7
Trembling, P.M.8
Mann, C.J.9
Shoulders, C.C.10
Graf, D.11
St Lezin, E.12
Kurtz, T.W.13
Kren, V.14
Prevanec, M.15
Ibrahimi, A.16
Abumrad, N.A.17
Stanton, L.W.18
Scott, J.19
-
121
-
-
0033578604
-
Muscle specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin
-
Ibrahimi A, Bonen A, Blinn WD, Hajri T, Li X, Zhong K, Cameron R, Abumrad NA. Muscle specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J Biol Chem 1999; 274: 26761-6.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26761-26766
-
-
Ibrahimi, A.1
Bonen, A.2
Blinn, W.D.3
Hajri, T.4
Li, X.5
Zhong, K.6
Cameron, R.7
Abumrad, N.A.8
-
122
-
-
0032006547
-
Skeletal muscle peroxisome proliferator-activated receptor g expression in obesity and non-insulin-dependent diabetes mellitus
-
Kruszynska YT, Mukherjee R, Jow L, Dana S, Paterniti Jr JR, Olefsky JM. Skeletal muscle peroxisome proliferator-activated receptor g expression in obesity and non-insulin-dependent diabetes mellitus. J Clin Invest 1998; 101: 543-8.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 543-548
-
-
Kruszynska, Y.T.1
Mukherjee, R.2
Jow, L.3
Dana, S.4
Paterniti Jr., J.R.5
Olefsky, J.M.6
-
123
-
-
0029791412
-
PPARα and PPARγ activators direct a tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
-
Schoonjans K, Peinado-Onsurbe J, Lefebvre AM, Heyman R, Briggs M, Deeb S, Staels B, Auwerx J. PPARα and PPARγ activators direct a tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J 1996; 15: 5336-48.
-
(1996)
EMBO J.
, vol.15
, pp. 5336-5348
-
-
Schoonjans, K.1
Peinado-Onsurbe, J.2
Lefebvre, A.M.3
Heyman, R.4
Briggs, M.5
Deeb, S.6
Staels, B.7
Auwerx, J.8
-
124
-
-
0029144018
-
Induction of acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter
-
Schoonjans K, Watanabe M, Suzuki H, Mahfoudi A, Krey G, Wahli W, Grimaldi P, Staels B, Yamamoto T, Auwerx J. Induction of acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter. J Biol Chem 1995; 270: 19269-76.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19269-19276
-
-
Schoonjans, K.1
Watanabe, M.2
Suzuki, H.3
Mahfoudi, A.4
Krey, G.5
Wahli, W.6
Grimaldi, P.7
Staels, B.8
Yamamoto, T.9
Auwerx, J.10
-
125
-
-
0029860791
-
Modulation on insulin activities by leptin
-
Cohen B, Novick D, Rubinstein M. Modulation on insulin activities by leptin. Science 1996; 274: 1185-8.
-
(1996)
Science
, vol.274
, pp. 1185-1188
-
-
Cohen, B.1
Novick, D.2
Rubinstein, M.3
-
126
-
-
0035905758
-
The hormone resistin links obesity to diabetes
-
Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Pattel HR, Ahima RS, Lazar MA. The hormone resistin links obesity to diabetes. Nature 2001; 409: 307-12.
-
(2001)
Nature
, vol.409
, pp. 307-312
-
-
Steppan, C.M.1
Bailey, S.T.2
Bhat, S.3
Brown, E.J.4
Banerjee, R.R.5
Wright, C.M.6
Pattel, H.R.7
Ahima, R.S.8
Lazar, M.A.9
-
127
-
-
0035851187
-
PPARγ: A nuclear regulator of metabolism, differentiation, and cell growth
-
Rosen ED, Spiegelman BM. PPARγ: a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem 2001; 276: 37731-4.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
128
-
-
0033603337
-
Tumor necrosis factor alpha-induced pancreatic beta-cell insulin resistance is mediated by nitric oxide and prevented by 15-deoxy-Delta 12,14-prostaglandin J2 and aminoguanidine. A role for peroxisome proliferator-activated receptor gamma activation and inos expression
-
Kwon G, Xu G, Marshall CA, McDaniel ML. Tumor necrosis factor alpha-induced pancreatic beta-cell insulin resistance is mediated by nitric oxide and prevented by 15-deoxy-Delta 12,14-prostaglandin J2 and aminoguanidine. A role for peroxisome proliferator-activated receptor gamma activation and inos expression. J Biol Chem 1999; 274: 18702-8.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18702-18708
-
-
Kwon, G.1
Xu, G.2
Marshall, C.A.3
McDaniel, M.L.4
-
129
-
-
0034096988
-
Plasma concentrations of the novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
-
Hotta K, Funahashi T, Arita Y, Takahashi M, Matsuda M, Okamoto Y, Iwahashi H, Kuriyama H, Ouchi N, Maeda K, Nishida M, Kihara S, Sakai N, Nakajima T, Hasegawa K, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Hanafusa T, Matsuzawa Y. Plasma concentrations of the novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Artheroscler Thromb Vasc Biol 2000; 20: 1595-9.
-
(2000)
Artheroscler. Thromb. Vasc. Biol.
, vol.20
, pp. 1595-1599
-
-
Hotta, K.1
Funahashi, T.2
Arita, Y.3
Takahashi, M.4
Matsuda, M.5
Okamoto, Y.6
Iwahashi, H.7
Kuriyama, H.8
Ouchi, N.9
Maeda, K.10
Nishida, M.11
Kihara, S.12
Sakai, N.13
Nakajima, T.14
Hasegawa, K.15
Muraguchi, M.16
Ohmoto, Y.17
Nakamura, T.18
Yamashita, S.19
Hanafusa, T.20
Matsuzawa, Y.21
more..
-
130
-
-
0035172839
-
Thiazolidinediones (PPARgamma agonists) but not PPAR alpha agonists increase IRS-2 gene expression in 3T3-L1 and human adipocytes
-
Smith U, Gogg S, Johansson A, Olausson T, Rotter V, Svalstedt B. Thiazolidinediones (PPARgamma agonists) but not PPAR alpha agonists increase IRS-2 gene expression in 3T3-L1 and human adipocytes. FASEB J 2001; 15: 215-20.
-
(2001)
FASEB J.
, vol.15
, pp. 215-220
-
-
Smith, U.1
Gogg, S.2
Johansson, A.3
Olausson, T.4
Rotter, V.5
Svalstedt, B.6
-
131
-
-
0033547443
-
Regulation of gene expression by activation of the peroxisome proliferator-activated receptor γ with Rosiglitazone (BRL 49653) in human adipocytes
-
Rieusset J, Auwerx J, Vidal H. Regulation of gene expression by activation of the peroxisome proliferator-activated receptor γ with Rosiglitazone (BRL 49653) in human adipocytes. Biochem Biophys Res Comm 1999; 265: 265-71.
-
(1999)
Biochem. Biophys. Res. Comm.
, vol.265
, pp. 265-271
-
-
Rieusset, J.1
Auwerx, J.2
Vidal, H.3
-
132
-
-
0031595111
-
PPAR γ induces the insulin-dependent glucose transporter GLUT4 in absence of C/EBPa during the conversion of 3T3 fibroblast into adipocytes
-
Wu Z, Xie Y, Morrison RF, Bucher NLR, Farmer SR. PPAR γ induces the insulin-dependent glucose transporter GLUT4 in absence of C/EBPa during the conversion of 3T3 fibroblast into adipocytes. J Clin Invest 1998; 101: 22-32.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 22-32
-
-
Wu, Z.1
Xie, Y.2
Morrison, R.F.3
Bucher, N.L.R.4
Farmer, S.R.5
-
133
-
-
0035091701
-
Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues
-
Way JM, Harrington WW, Brown KK, Gottshalk WK, Sundsetb SS, Mansfield TA, Ramachandran RK, Wilson TM, Kliewer SA. Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues. Endocrinology 2001; 142: 1269-77.
-
(2001)
Endocrinology
, vol.142
, pp. 1269-1277
-
-
Way, J.M.1
Harrington, W.W.2
Brown, K.K.3
Gottshalk, W.K.4
Sundsetb, S.S.5
Mansfield, T.A.6
Ramachandran, R.K.7
Wilson, T.M.8
Kliewer, S.A.9
-
134
-
-
0033864402
-
Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter
-
Kim HI, Kim JW, Kim SH, Cha JY, Kim KS, Ahn YH. Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter. Diabetes 2000; 49: 1517-24.
-
(2000)
Diabetes
, vol.49
, pp. 1517-1524
-
-
Kim, H.I.1
Kim, J.W.2
Kim, S.H.3
Cha, J.Y.4
Kim, K.S.5
Ahn, Y.H.6
-
135
-
-
0036399805
-
PPAR g and glucose homeostasis
-
Picard F, Auwerx J, PPAR g and glucose homeostasis. Ann Rev Nutr 2002; 22: 167-97.
-
(2002)
Ann. Rev. Nutr.
, vol.22
, pp. 167-197
-
-
Picard, F.1
Auwerx, J.2
-
136
-
-
0033681001
-
Asymmetry in the PPAR gamma/RXR alpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors
-
Gampe RTJ, Montana VG, Lambert MH, Miller AB, Bledsoe RK, Milburn MV, Kliewer SA, Willson TM, Xu HE. Asymmetry in the PPAR gamma/RXR alpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors. Mol Cell 2000; 5: 545-55.
-
(2000)
Mol. Cell
, vol.5
, pp. 545-555
-
-
Gampe, R.T.J.1
Montana, V.G.2
Lambert, M.H.3
Miller, A.B.4
Bledsoe, R.K.5
Milburn, M.V.6
Kliewer, S.A.7
Willson, T.M.8
Xu, H.E.9
-
137
-
-
2642557181
-
A unique PPAR-gamma ligand with potent insulin-sensitizing yet weak adipogenic activity
-
Rocchi S, Picard F, Vamecq J, Getman L, Potier N, Zeyer D, Dubuquoy L, Bac P, Champy MF, Plunket KD, Leesnitzer LM, Blanchard SG, Desreumaux P, Moras D, Renaud JP, Auwerx J. A unique PPAR-gamma ligand with potent insulin-sensitizing yet weak adipogenic activity. Mol Cell 2001; 8: 737-47.
-
(2001)
Mol. Cell
, vol.8
, pp. 737-747
-
-
Rocchi, S.1
Picard, F.2
Vamecq, J.3
Getman, L.4
Potier, N.5
Zeyer, D.6
Dubuquoy, L.7
Bac, P.8
Champy, M.F.9
Plunket, K.D.10
Leesnitzer, L.M.11
Blanchard, S.G.12
Desreumaux, P.13
Moras, D.14
Renaud, J.P.15
Auwerx, J.16
-
138
-
-
0034693323
-
Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions bttween peroxisome proliferator activated receptor gamma and nuclear factor-k B
-
Chung SW, Kang BY, Kim SH, Pak YK, Cho D, Trinchieri G, Kim TS. Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions bttween peroxisome proliferator activated receptor gamma and nuclear factor-k B. J Biol Chem 2000; 275: 32681-7.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32681-32687
-
-
Chung, S.W.1
Kang, B.Y.2
Kim, S.H.3
Pak, Y.K.4
Cho, D.5
Trinchieri, G.6
Kim, T.S.7
-
139
-
-
0033520304
-
Peroxisome pro liferator-activated receptor activators inhibit th rombin- induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway
-
Delerive P. Peroxisome pro liferator-activated receptor activators inhibit th rombin- induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway. Circ Res 1999; 85: 394-402.
-
(1999)
Circ. Res.
, vol.85
, pp. 394-402
-
-
Delerive, P.1
-
140
-
-
0034650330
-
Activation of peroxisome proliferator-activated receptor gamma does not inhibit IL-6 or TNF-alpha responses of macrophages to lipopolisaccharie in vitro or in vivo
-
Thieringer R, Fenyk-Melody JE, Le Grand CB, Shelton BA, Detmers PA, Somers EP, Carbin L, Moller DE, Wright SD, Berger J. Activation of peroxisome proliferator-activated receptor gamma does not inhibit IL-6 or TNF-alpha responses of macrophages to lipopolisaccharie in vitro or in vivo. J Immunol 2000; 164: 1046-54.
-
(2000)
J. Immunol.
, vol.164
, pp. 1046-1054
-
-
Thieringer, R.1
Fenyk-Melody, J.E.2
Le Grand, C.B.3
Shelton, B.A.4
Detmers, P.A.5
Somers, E.P.6
Carbin, L.7
Moller, D.E.8
Wright, S.D.9
Berger, J.10
-
142
-
-
0024362168
-
Role of thermogenesis in the replation of energy balance in relation to obesity
-
Himms-Hagen J. Role of thermogenesis in the replation of energy balance in relation to obesity. Can J Physiol Pharmacol 1989; 67: 394-401.
-
(1989)
Can. J. Physiol. Pharmacol.
, vol.67
, pp. 394-401
-
-
Himms-Hagen, J.1
-
143
-
-
0031048115
-
Increased lipogenic capacity of the islets of obese rats. A role in the pathogenesis of NIDDM
-
Lee Y, Hirose H, Zhou Y-T, Esser V, McGarry JD, Unger RH. Increased lipogenic capacity of the islets of obese rats. A role in the pathogenesis of NIDDM. Diabetes 1997; 46: 408-13.
-
(1997)
Diabetes
, vol.46
, pp. 408-413
-
-
Lee, Y.1
Hirose, H.2
Zhou, Y.-T.3
Esser, V.4
McGarry, J.D.5
Unger, R.H.6
-
144
-
-
0032484132
-
Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyl transferase overexpression
-
Shimabukuro M, Zhou Y-T, Levi M, Unger RH. Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyl transferase overexpression. J Biol Chem 1998; 273: 32487-90.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32487-32490
-
-
Shimabukuro, M.1
Zhou, Y.-T.2
Levi, M.3
Unger, R.H.4
-
145
-
-
0035937174
-
Liporegulation in diet-induced obesity. The antiesteatotic role of hyperleptinemia
-
Lee Y, Wang MY, Kakuma T, Wang ZW, Babcock E, McCorkle K, Higa M, Zhou Y-T, Unger RH. Liporegulation in diet-induced obesity. The antiesteatotic role of hyperleptinemia. J Biol Chem 2001; 276: 5629-35.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5629-5635
-
-
Lee, Y.1
Wang, M.Y.2
Kakuma, T.3
Wang, Z.W.4
Babcock, E.5
McCorkle, K.6
Higa, M.7
Zhou, Y.-T.8
Unger, R.H.9
-
146
-
-
0036182137
-
Lipotoxic diseases
-
Unger RH. Lipotoxic diseases. Ann Rev Med 2002; 53: 319-36.
-
(2002)
Ann. Rev. Med.
, vol.53
, pp. 319-336
-
-
Unger, R.H.1
-
147
-
-
0003851317
-
Dietary references values for food energy and nutrients for the United Kingdom. Report of the panel on dietary reference values of the committee on medical aspects of food policy
-
Her Majesty's Stationery Office. London
-
Dietary references values for food energy and nutrients for the United Kingdom. Report of the panel on dietary reference values of the committee on medical aspects of food policy. Her Majesty's Stationery Office. London, 1991.
-
(1991)
-
-
-
148
-
-
0037872202
-
Task force on unsaturated fatty acids
-
Chapman and Hall
-
Task force on unsaturated fatty acids. Chapman and Hall. 1992.
-
(1992)
-
-
-
149
-
-
0028715652
-
Fats and oils in human nutrition report of a joint expert consultation
-
FAO/WHO. Health Organization FAO Food and Agriculture Organization of the United Nations and the World
-
FAO/WHO. Fats and oils in human nutrition report of a joint expert consultation. Food and Agriculture Organization of the United Nations and the World Health Organization. FAO Food Nutr Pap 1994; 57: 1-147.
-
(1994)
Food Nutr. Pap.
, vol.57
, pp. 1-147
-
-
-
150
-
-
0033954765
-
Polyunsaturated fatty acids in the food chain in the United States
-
S
-
Kris-Etherton PM, Shaffer Taylor D, Yu-Poth S, Huth P, Moriarty K, Fishell V, Hargrove RL, Zhao G, Etherton TD. Polyunsaturated fatty acids in the food chain in the United States. Am J Clin Nutr 2000; 71: 179S-88S.
-
(2000)
Am. J. Clin. Nutr.
, vol.71
-
-
Kris-Etherton, P.M.1
Shaffer Taylor, D.2
Yu-Poth, S.3
Huth4
-
151
-
-
4544366440
-
Biological activities and requirements for polyunsaturated fatty acids
-
Pergamon Press. New York
-
Holman RT. Biological activities and requirements for polyunsaturated fatty acids. Pergamon Press. New York, 1970.
-
(1970)
-
-
Holman, R.T.1
-
152
-
-
0033966347
-
Safety considerations of polyunsaturated fatty acids
-
Eritsland J. Safety considerations of polyunsaturated fatty acids. Am J Clin Nutr 2000; 71(Suppl.): 197S-201S.
-
(2000)
Am. J. Clin. Nutr.
, vol.71
, Issue.SUPPL.
-
-
Eritsland, J.1
-
153
-
-
0019949107
-
Polyunsaturated fatty acids, hyperlipidemia, and thrombosis
-
Goodnight SH, Harris WS, Connor WE, Illingworth DR. Polyunsaturated fatty acids, hyperlipidemia, and thrombosis. Arteriosclerosis 1982; 2: 87-113.
-
(1982)
Arteriosclerosis
, vol.2
, pp. 87-113
-
-
Goodnight, S.H.1
Harris, W.S.2
Connor, W.E.3
Illingworth, D.R.4
-
154
-
-
0043069942
-
Nutrition and genetics: An expanding frontier
-
Olson RE. Nutrition and genetics: an expanding frontier. Am J Clin Nutr 2003; 78: 201-8.
-
(2003)
Am. J. Clin. Nutr.
, vol.78
, pp. 201-208
-
-
Olson, R.E.1
-
155
-
-
0037255574
-
Evidence for the presence of both peroxisome proliferator-activated receptors alpha and beta in the rat spinal cord
-
Benani A, Kremarik-Bouillaud P, Bianchi A, Netter P, Minn A, Dauca M. Evidence for the presence of both peroxisome proliferator-activated receptors alpha and beta in the rat spinal cord. J Chem Neuroanat 2003; 25: 29-38.
-
(2003)
J. Chem. Neuroanat.
, vol.25
, pp. 29-38
-
-
Benani, A.1
Kremarik-Bouillaud, P.2
Bianchi, A.3
Netter, P.4
Minn, A.5
Dauca, M.6
-
156
-
-
0032489437
-
Altered constitutive expression of fatty acid metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor a deficient mice
-
Aoyama T, Peters JM, Iritani N, Nakajima T, Furihata K, Hashimoto T, Gonzalez FJ. Altered constitutive expression of fatty acid metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor a deficient mice. J Biol Chem 1998; 273: 5678-84.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5678-5684
-
-
Aoyama, T.1
Peters, J.M.2
Iritani, N.3
Nakajima, T.4
Furihata, K.5
Hashimoto, T.6
Gonzalez, F.J.7
-
157
-
-
0030766476
-
Alterations in lipoprotein metabolism in peroxisome pro liferator-activated receptor a deficient mice
-
Peters JM, Hennuyer N, Staels B, Fruchart JC, Fievet C, Gonzalez FJ, Auwerx J. Alterations in lipoprotein metabolism in peroxisome pro liferator-activated receptor a deficient mice. J Biol Chem 1997; 272: 27307-12.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27307-27312
-
-
Peters, J.M.1
Hennuyer, N.2
Staels, B.3
Fruchart, J.C.4
Fievet, C.5
Gonzalez, F.J.6
Auwerx, J.7
-
158
-
-
0034023449
-
Evidence against the peroxisome proliferator-activated receptor a (PPARa) as the mediator for polyunsaturated fatty acid suppression of hepatic L-pyruvate kinase gene transcription
-
Pan DA, Mater MK, Thelen AP, Peters JM, Gonzalez FJ, Jump DB. Evidence against the peroxisome proliferator-activated receptor a (PPARa) as the mediator for polyunsaturated fatty acid suppression of hepatic L-pyruvate kinase gene transcription. J Lipid Res 2000; 41: 742-51.
-
(2000)
J. Lipid. Res.
, vol.41
, pp. 742-751
-
-
Pan, D.A.1
Mater, M.K.2
Thelen, A.P.3
Peters, J.M.4
Gonzalez, F.J.5
Jump, D.B.6
-
159
-
-
0028003839
-
Regulation of the peroxisome proliferator-activated receptor a gene by glucocorticoids
-
Lemberger T, Staels B, Saladin R, Desvergne B, Auwerx J, Wahli W. Regulation of the peroxisome proliferator-activated receptor a gene by glucocorticoids. J Biol Chem 1994; 269: 24527-30.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24527-24530
-
-
Lemberger, T.1
Staels, B.2
Saladin, R.3
Desvergne, B.4
Auwerx, J.5
Wahli, W.6
-
160
-
-
0028131951
-
Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the peroxisomal proliferator-activated receptor (PPAR) in hepatic cells - Hormonal modulation of fatty acid induced transcription
-
Steineger HH, Sorensen HN, Tugwood JD, Skrede S, Spydevold O, Gautvik KM, Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the peroxisomal proliferator-activated receptor (PPAR) in hepatic cells - hormonal modulation of fatty acid induced transcription. Eur J Biochem 1994; 225: 967-74.
-
(1994)
Eur. J. Biochem.
, vol.225
, pp. 967-974
-
-
Steineger, H.H.1
Sorensen, H.N.2
Tugwood, J.D.3
Skrede, S.4
Spydevold, O.5
Gautvik, K.M.6
-
161
-
-
0033625677
-
Growth, adipose, brain and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator activated receptor beta (delta)
-
Peters JM, Lee SS, Li W. Growth, adipose, brain and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator activated receptor beta (delta). Mol Cell Biol 2000; 20: 5119-28.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 5119-5128
-
-
Peters, J.M.1
Lee, S.S.2
Li, W.3
-
162
-
-
0031898610
-
PPAR g adipogenic regulator and thiazolidinedione receptor
-
Spiegelman BM. PPAR g adipogenic regulator and thiazolidinedione receptor. Diabetes 1998; 47: 507-14.
-
(1998)
Diabetes
, vol.47
, pp. 507-514
-
-
Spiegelman, B.M.1
|