메뉴 건너뛰기




Volumn 15, Issue 19, 1996, Pages 5336-5348

PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene

Author keywords

Atherosclerosis; Gene expression; Lipoproteins; Nuclear receptors; Peroxisomes

Indexed keywords

CELL NUCLEUS RECEPTOR; FENOFIBRIC ACID; LIPOPROTEIN; LIPOPROTEIN LIPASE; PEROXISOME PROLIFERATOR; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; CELL RECEPTOR; DNA; DRUG DERIVATIVE; FENOFIBRATE; MESSENGER RNA; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; ROSIGLITAZONE; THIAZOLE DERIVATIVE; TRANSCRIPTION FACTOR;

EID: 0029791412     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00918.x     Document Type: Article
Times cited : (1044)

References (83)
  • 1
    • 0026443622 scopus 로고
    • Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles
    • Aalto-Setälä, K. et al. (1992) Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles. J. Clin. Invest., 90, 1889-1900.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1889-1900
    • Aalto-Setälä, K.1
  • 2
    • 0028354055 scopus 로고
    • An upstream region of the enoyl-coenzyme A hydratase 3-hydroxyacyl-coenzyme A dehydrogenase gene directs luciferase expression in liver in response to peroxisome proliferators in transgenic mice
    • Alvarez, K. et al. (1994) An upstream region of the enoyl-coenzyme A hydratase 3-hydroxyacyl-coenzyme A dehydrogenase gene directs luciferase expression in liver in response to peroxisome proliferators in transgenic mice. Cancer Res., 54, 2303-2306.
    • (1994) Cancer Res. , vol.54 , pp. 2303-2306
    • Alvarez, K.1
  • 3
    • 0025951065 scopus 로고
    • Regulation of adipose cell differentiation. I. Fatty acids are inducers of the aP2 gene expression
    • Amri, E.-Z., Bertrand, B., Ailhaud, G. and Grimaldi, P. (1991) Regulation of adipose cell differentiation. I. Fatty acids are inducers of the aP2 gene expression. J. Lipid Res., 32, 1449-1456.
    • (1991) J. Lipid Res. , vol.32 , pp. 1449-1456
    • Amri, E.-Z.1    Bertrand, B.2    Ailhaud, G.3    Grimaldi, P.4
  • 4
    • 0028909362 scopus 로고
    • Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes
    • Amri, E.-Z., Bonino, F., Ailhaud, G., Abumrad, N.A. and Grimaldi, P.A. (1995) Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. J Biol. Chem., 270, 2367-2371.
    • (1995) J Biol. Chem. , vol.270 , pp. 2367-2371
    • Amri, E.-Z.1    Bonino, F.2    Ailhaud, G.3    Abumrad, N.A.4    Grimaldi, P.A.5
  • 5
    • 0029121281 scopus 로고
    • Isolation and characterization of the hamster peroxisomal proliferator activated receptor hPPARγ, a member of the nuclear hormone receptor superfamily
    • Aperlo, C., Pognonec, P., Saladin, R., Auwerx, J. and Boulukos, K. (1995) Isolation and characterization of the hamster peroxisomal proliferator activated receptor hPPARγ, a member of the nuclear hormone receptor superfamily. Gene, 162, 297-302.
    • (1995) Gene , vol.162 , pp. 297-302
    • Aperlo, C.1    Pognonec, P.2    Saladin, R.3    Auwerx, J.4    Boulukos, K.5
  • 7
    • 0027099736 scopus 로고
    • Lipoprotein lipase: Recent contributions from molecular biology
    • Auwerx, J., Leroy, P. and Schoonjans, K. (1992) Lipoprotein lipase: recent contributions from molecular biology. Crit. Rev. Clin. Lab. Sci., 29, 243-268.
    • (1992) Crit. Rev. Clin. Lab. Sci. , vol.29 , pp. 243-268
    • Auwerx, J.1    Leroy, P.2    Schoonjans, K.3
  • 8
    • 0027161015 scopus 로고
    • PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene
    • Bardot, O., Aldridge, T.C., Latruffe, N. and Green, S. (1993) PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene. Biochem. Biophys. Res. Commun., 192, 37-45.
    • (1993) Biochem. Biophys. Res. Commun. , vol.192 , pp. 37-45
    • Bardot, O.1    Aldridge, T.C.2    Latruffe, N.3    Green, S.4
  • 9
    • 0029130373 scopus 로고
    • Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153)
    • Batchvarova, N., Wang, X.-Z. and Ron, D. (1995) Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). EMBO J., 14, 4654-4661.
    • (1995) EMBO J. , vol.14 , pp. 4654-4661
    • Batchvarova, N.1    Wang, X.-Z.2    Ron, D.3
  • 10
    • 0026536019 scopus 로고
    • The ontogeny of peroxisome-proliferator-activated receptor gene expression in the mouse and rat
    • Beck, F., Plummer, S., Senior, P.V., Byrne, S., Green, S. and Brammar, W.J. (1992) The ontogeny of peroxisome-proliferator-activated receptor gene expression in the mouse and rat. Proc. R. Soc. Lond. Biol., 247, 83-87.
    • (1992) Proc. R. Soc. Lond. Biol. , vol.247 , pp. 83-87
    • Beck, F.1    Plummer, S.2    Senior, P.V.3    Byrne, S.4    Green, S.5    Brammar, W.J.6
  • 11
    • 0030047806 scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors: Tissue distribution of PPARα, β and γ in the adult rat
    • Braissant, O., Foufelle, F., Scotto, C., Dauca, M. and Wahli, W. (1995) Differential expression of peroxisome proliferator-activated receptors: tissue distribution of PPARα, β and γ in the adult rat. Endocrinology, 137, 354-366.
    • (1995) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 14
    • 0028202490 scopus 로고
    • Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival
    • Chawla, A. and Lazar, M.A. (1994) Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival. Proc. Natl Acad. Sci. USA, 91, 1786-1790.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 1786-1790
    • Chawla, A.1    Lazar, M.A.2
  • 15
    • 0028069690 scopus 로고
    • Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E
    • de Silva, H.V., Lauer, S.J., Wang, J., Simonet, W.S., Weisgraber, K.H., Mahley, R.W. and Taylor, J.M. (1994) Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E. J. Biol. Chem., 269, 2324-2335.
    • (1994) J. Biol. Chem. , vol.269 , pp. 2324-2335
    • De Silva, H.V.1    Lauer, S.J.2    Wang, J.3    Simonet, W.S.4    Weisgraber, K.H.5    Mahley, R.W.6    Taylor, J.M.7
  • 16
    • 2642643399 scopus 로고    scopus 로고
    • Thiazolidinediones repress ob gene expression via activation of PPARγ
    • in press
    • De Vos, P. et al. (1996) Thiazolidinediones repress ob gene expression via activation of PPARγ. J. Clin. Invest., in press.
    • (1996) J. Clin. Invest.
    • De Vos, P.1
  • 17
    • 0024397097 scopus 로고
    • Structure of the human lipoprotein lipase gene
    • Deeb, S. and Peng, R. (1989) Structure of the human lipoprotein lipase gene. Biochemistry, 28, 4131-4135.
    • (1989) Biochemistry , vol.28 , pp. 4131-4135
    • Deeb, S.1    Peng, R.2
  • 18
    • 0026739556 scopus 로고
    • Fatty acid regulation of gene expression: Transcriptional and post-transcriptional mechanisms
    • Distel, R.J., Robinson, G.S. and Spiegelman, B.M. (1992) Fatty acid regulation of gene expression: transcriptional and post-transcriptional mechanisms. J. Biol. Chem., 267, 5937-5941.
    • (1992) J. Biol. Chem. , vol.267 , pp. 5937-5941
    • Distel, R.J.1    Robinson, G.S.2    Spiegelman, B.M.3
  • 19
    • 0026517010 scopus 로고
    • Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
    • Dreyer, C., Krey, G., Keller, H., Givel, F., Helftenbein, G. and Wahli, W. (1992) Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors. Cell, 68, 879-887.
    • (1992) Cell , vol.68 , pp. 879-887
    • Dreyer, C.1    Krey, G.2    Keller, H.3    Givel, F.4    Helftenbein, G.5    Wahli, W.6
  • 20
    • 0027278522 scopus 로고
    • Positive regulation of peroxisomal β-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR)
    • Dreyer, C., Keller, H., Mahfoudi, A., Laudet, V., Krey, G. and Wahli, W. (1993) Positive regulation of peroxisomal β-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR). Biol. Cell, 77, 67-77.
    • (1993) Biol. Cell , vol.77 , pp. 67-77
    • Dreyer, C.1    Keller, H.2    Mahfoudi, A.3    Laudet, V.4    Krey, G.5    Wahli, W.6
  • 21
    • 0007661403 scopus 로고
    • Syndromes of insulin resistance and mutant insulin
    • De Groot, L.J. (ed.), W.B.Saunders, Philadelphia, PA
    • Flier, J.S. (1995) Syndromes of insulin resistance and mutant insulin. In De Groot, L.J. (ed.), Endocrinology. W.B.Saunders, Philadelphia, PA, pp. 1592-1604.
    • (1995) Endocrinology , pp. 1592-1604
    • Flier, J.S.1
  • 22
    • 0028972025 scopus 로고
    • 15-Deoxy-Δ12,14 prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
    • Forman, B.M., Tontonoz, P., Chen, J., Brun, R.P., Spiegelman, B.M. and Evans, R.M. (1995) 15-Deoxy-Δ12,14 prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ. Cell, 83, 803-812.
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 23
    • 0021100539 scopus 로고
    • CAP and RNA polymerase interactions with the lac promoter: Binding stoichiometry and long range effects
    • Fried, M.G. and Crothers, D.M. (1983) CAP and RNA polymerase interactions with the lac promoter: binding stoichiometry and long range effects. Nucleic Acids Res., 11, 141-158.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 141-158
    • Fried, M.G.1    Crothers, D.M.2
  • 24
    • 0024589193 scopus 로고
    • Requirement and role of arachidonic acid in the differentiation of pre-adipose cells
    • Gaillard, D., Negrel, R., Lagarde, M. and Ailhaud, G. (1989) Requirement and role of arachidonic acid in the differentiation of pre-adipose cells. Biochem. J., 257, 389-397.
    • (1989) Biochem. J. , vol.257 , pp. 389-397
    • Gaillard, D.1    Negrel, R.2    Lagarde, M.3    Ailhaud, G.4
  • 25
    • 0022538038 scopus 로고
    • Effect of gemfibrozil on lipids, apoproteins, and postheparin lipolytic activities in normolipidemic subjects
    • Gnasso, A., Lehner, B., Haberbosch, W., Leiss, O., von Bergman, K. and Augustin, J. (1986) Effect of gemfibrozil on lipids, apoproteins, and postheparin lipolytic activities in normolipidemic subjects. Metabolism, 35, 387-394.
    • (1986) Metabolism , vol.35 , pp. 387-394
    • Gnasso, A.1    Lehner, B.2    Haberbosch, W.3    Leiss, O.4    Von Bergman, K.5    Augustin, J.6
  • 26
    • 0026551309 scopus 로고
    • Fatty acids activate chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
    • Gottlicher, M., Widmark, E., Li, Q. and Gustafsson, J.A. (1992) Fatty acids activate chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. Proc. Natl Acad. Sci. USA, 89, 4653-4657.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 4653-4657
    • Gottlicher, M.1    Widmark, E.2    Li, Q.3    Gustafsson, J.A.4
  • 27
    • 0025280487 scopus 로고
    • Dietary influences on serum lipids and lipoproteins
    • Grundy, S.M. and Denke, M.A. (1990) Dietary influences on serum lipids and lipoproteins. J. Lipid Res., 31, 1149-1172.
    • (1990) J. Lipid Res. , vol.31 , pp. 1149-1172
    • Grundy, S.M.1    Denke, M.A.2
  • 28
    • 0028033268 scopus 로고
    • The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression
    • Gulick, T., Cresci, S., Caira, T., Moore, D.D. and Kelly, D.P. (1994) The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc. Natl Acad. Sci. USA, 91, 11012-11016.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 11012-11016
    • Gulick, T.1    Cresci, S.2    Caira, T.3    Moore, D.D.4    Kelly, D.P.5
  • 29
    • 0020533327 scopus 로고
    • Effects of clofibrate, bezafibrate, fenofibrate, and probucol on plasma lipolytic enzymes in normolipidaemic subjects
    • Heller, F. and Harvengt, C. (1983) Effects of clofibrate, bezafibrate, fenofibrate, and probucol on plasma lipolytic enzymes in normolipidaemic subjects. Eur. J. Clin. Pharmacol., 23, 57-63.
    • (1983) Eur. J. Clin. Pharmacol. , vol.23 , pp. 57-63
    • Heller, F.1    Harvengt, C.2
  • 30
    • 0028998129 scopus 로고
    • Mode of action of peroxisome proliferators as hypolipidemic drugs, suppression of apolipoprotein C-III
    • Hertz, R., Bishara-Shieban, J. and Bar-Tana, J. (1995) Mode of action of peroxisome proliferators as hypolipidemic drugs, suppression of apolipoprotein C-III. J. Biol. Chem., 270, 13470-13475.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13470-13475
    • Hertz, R.1    Bishara-Shieban, J.2    Bar-Tana, J.3
  • 31
    • 0023850852 scopus 로고
    • Preadipocyte differentiation in vitro: Identification of a highly active adipogenic agent
    • Hiragun, A., Sato, M. and Mitsui, H. (1988) Preadipocyte differentiation in vitro: identification of a highly active adipogenic agent. J. Cell. Physiol., 134, 124-130.
    • (1988) J. Cell. Physiol. , vol.134 , pp. 124-130
    • Hiragun, A.1    Sato, M.2    Mitsui, H.3
  • 32
    • 0028871780 scopus 로고
    • Transdifferentiation of myoblasts by the adipogenic transcription factors PPARgamma and C/EBPalpha
    • Hu, E., Tontonoz, P. and Spiegelman, B.M. (1995) Transdifferentiation of myoblasts by the adipogenic transcription factors PPARgamma and C/EBPalpha. Proc. Natl Acad. Sci. USA, 92, 9856-9860.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 9856-9860
    • Hu, E.1    Tontonoz, P.2    Spiegelman, B.M.3
  • 33
    • 0026002460 scopus 로고
    • Cloning and characterization of the murine lipoprotein lipase-encoding gene: Structural and functional analysis
    • Hua, X., Enerback, S., Hudson, J., Youkhana, K. and Gimble, J.M. (1991) Cloning and characterization of the murine lipoprotein lipase-encoding gene: structural and functional analysis. Gene, 107, 247-258.
    • (1991) Gene , vol.107 , pp. 247-258
    • Hua, X.1    Enerback, S.2    Hudson, J.3    Youkhana, K.4    Gimble, J.M.5
  • 34
    • 0025022272 scopus 로고
    • Effects of pioglitazone on glucose and lipid metabolism in normal and insulin resistent animals
    • Ikeda, H., Taketomi, S., Sugiyama, Y., Shimura, Y., Sohda, T., Meguro, K. and Fujita, T. (1990) Effects of pioglitazone on glucose and lipid metabolism in normal and insulin resistent animals. Drug Res., 40, 156-162.
    • (1990) Drug Res. , vol.40 , pp. 156-162
    • Ikeda, H.1    Taketomi, S.2    Sugiyama, Y.3    Shimura, Y.4    Sohda, T.5    Meguro, K.6    Fujita, T.7
  • 35
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Isseman, I. and Green, S. (1990) Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature, 347, 645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Isseman, I.1    Green, S.2
  • 36
    • 0027447461 scopus 로고
    • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers
    • Keller, H., Dreyer, C., Medin, J., Mahfoudi, A., Ozato, K. and Wahli, W. (1993) Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc. Natl Acad. Sci. USA, 90, 2160-2164.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 2160-2164
    • Keller, H.1    Dreyer, C.2    Medin, J.3    Mahfoudi, A.4    Ozato, K.5    Wahli, W.6
  • 37
    • 0026517080 scopus 로고
    • Enhancement of adipocyte differentiation by an insulin sensitizing agent
    • Kletzien, R.F., Clarke, S.D. and Ulrich, R.G. (1992) Enhancement of adipocyte differentiation by an insulin sensitizing agent. Mol. Pharmacol., 41, 393-398.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 393-398
    • Kletzien, R.F.1    Clarke, S.D.2    Ulrich, R.G.3
  • 39
    • 0028972026 scopus 로고
    • A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
    • Kliewer, S.A., Lenhard, J.M., Willson, T.M., Patel, I., Morris, D.C. and Lehman, J.M. (1995) A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell, 83, 813-819.
    • (1995) Cell , vol.83 , pp. 813-819
    • Kliewer, S.A.1    Lenhard, J.M.2    Willson, T.M.3    Patel, I.4    Morris, D.C.5    Lehman, J.M.6
  • 40
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for Peroxisome Proliferator-Activated Receptor γ (PPARy)
    • Lehmann, J.M., Moore, L.B., Smith-Oliver, T.A., Wilkison, W.O., Willson, T.M. and Kliewer, S.A. (1995) An antidiabetic thiazolidinedione is a high affinity ligand for Peroxisome Proliferator-Activated Receptor γ (PPARy). J. Biol. Chem., 270, 12953-12956.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 41
    • 0026570217 scopus 로고
    • Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently
    • Leid, M. et al. (1992) Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. Cell, 68, 377-395.
    • (1992) Cell , vol.68 , pp. 377-395
    • Leid, M.1
  • 42
    • 0027322690 scopus 로고
    • Beneficial effect of fish-oil supplements on lipids, lipoproteins, and lipoprotein lipase in patients with glycogen storage disease type I
    • Levy, E., Thibault, L., Turgeon, J., Roy, C.C., Gurbindo, C., Lepage, G., Godard, M., Rivard, G.E. and Seidman, E. (1993) Beneficial effect of fish-oil supplements on lipids, lipoproteins, and lipoprotein lipase in patients with glycogen storage disease type I. Am. J. Clin. Nutr., 57, 922-929.
    • (1993) Am. J. Clin. Nutr. , vol.57 , pp. 922-929
    • Levy, E.1    Thibault, L.2    Turgeon, J.3    Roy, C.C.4    Gurbindo, C.5    Lepage, G.6    Godard, M.7    Rivard, G.E.8    Seidman, E.9
  • 43
    • 0024509605 scopus 로고
    • Biochemical mechanisms of induction of hepatic peroxisome proliferation
    • Lock, E.A., Mitchell, A.M. and Elcombe, C.R. (1989) Biochemical mechanisms of induction of hepatic peroxisome proliferation. Annu. Rev. Pharmacol. Toxicol., 29, 145-163.
    • (1989) Annu. Rev. Pharmacol. Toxicol. , vol.29 , pp. 145-163
    • Lock, E.A.1    Mitchell, A.M.2    Elcombe, C.R.3
  • 44
    • 0023649835 scopus 로고
    • CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements
    • Luckow, B. and Schütz, G. (1987) CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res., 15, 5490.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 5490
    • Luckow, B.1    Schütz, G.2
  • 45
    • 0028914922 scopus 로고
    • Thiazolidine derivatives ameliorate high glucose-induced insulin resistance via the normalization of protein-tyrosine phosphatase activities
    • Maegawa, H., Ide, R., Hasegawa, M., Ugi, S., Egawa, K., Iwanishi, M., Kikkawa, R., Shigeta, Y. and Kashigawa, .A. (1995) Thiazolidine derivatives ameliorate high glucose-induced insulin resistance via the normalization of protein-tyrosine phosphatase activities. J. Biol. Chem., 270, 7724-7730.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7724-7730
    • Maegawa, H.1    Ide, R.2    Hasegawa, M.3    Ugi, S.4    Egawa, K.5    Iwanishi, M.6    Kikkawa, R.7    Shigeta, Y.8    Kashigawa, A.9
  • 46
    • 0027214910 scopus 로고
    • Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive element of the rat hydratase/dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression
    • Marcus, S.L., Miyata, K.S., Zhang, B., Subramani, S., Rachubinski, R.A. and Capone, J.P. (1993) Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive element of the rat hydratase/dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression. Proc. Natl Acad. Sci. USA, 90, 5723-5727.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 5723-5727
    • Marcus, S.L.1    Miyata, K.S.2    Zhang, B.3    Subramani, S.4    Rachubinski, R.A.5    Capone, J.P.6
  • 47
    • 0029081813 scopus 로고
    • Severe obesity: Expensive to society, frustrating to treat, but important to confront
    • Martin, L.F., Hunter, S., Lauve, R.M. and O'Leary, J.P. (1995) Severe obesity: expensive to society, frustrating to treat, but important to confront. Southern Med. J., 88, 895-902.
    • (1995) Southern Med. J. , vol.88 , pp. 895-902
    • Martin, L.F.1    Hunter, S.2    Lauve, R.M.3    O'Leary, J.P.4
  • 48
    • 0020488029 scopus 로고
    • Cloning of cDNA sequences of hormone-regulated genes from MCF-7 human breast cancer cell line
    • Masiakowski, P., Breathnach, R., Bloch, J., Gannon, F., Krust, A., and Chambon, P. (1982) Cloning of cDNA sequences of hormone-regulated genes from MCF-7 human breast cancer cell line. Nucleic Acids Res., 10, 7895-7903.
    • (1982) Nucleic Acids Res. , vol.10 , pp. 7895-7903
    • Masiakowski, P.1    Breathnach, R.2    Bloch, J.3    Gannon, F.4    Krust, A.5    Chambon, P.6
  • 49
    • 0025945012 scopus 로고
    • Insulin resistance-mechanisms, syndromes, and implications
    • Moller, D.E. and Flier, J.S. (1991) Insulin resistance-mechanisms, syndromes, and implications. New Engl. J. Med., 325, 938-948.
    • (1991) New Engl. J. Med. , vol.325 , pp. 938-948
    • Moller, D.E.1    Flier, J.S.2
  • 50
    • 0026730908 scopus 로고
    • The peroxisome proliferator activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid ω-hydroxylase, by clofibric acid
    • Muerhoff, A.S., Griffin, K.J. and Johnson, E.F. (1992) The peroxisome proliferator activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid ω-hydroxylase, by clofibric acid. J. Biol. Chem., 267, 19051-19053.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19051-19053
    • Muerhoff, A.S.1    Griffin, K.J.2    Johnson, E.F.3
  • 51
    • 0344070478 scopus 로고
    • Establishment of preadipocyte clonal cell line from epididymal fat pad of ob/ob mouse that responds to insulin and to lipolytic hormones
    • Negrel, R., Grimaldi, P. and Ailhaud, G. (1978) Establishment of preadipocyte clonal cell line from epididymal fat pad of ob/ob mouse that responds to insulin and to lipolytic hormones. Proc. Natl Acad. Sci. USA, 75, 6054-6058.
    • (1978) Proc. Natl Acad. Sci. USA , vol.75 , pp. 6054-6058
    • Negrel, R.1    Grimaldi, P.2    Ailhaud, G.3
  • 53
    • 0025726848 scopus 로고
    • Two cis-acting regulatory elements in the peroxisome proliferator-responsive element enhancer region of rat acyl-CoA oxidase gene
    • Osumi, T., Wen, J.K. and Hashimoto, T. (1991) Two cis-acting regulatory elements in the peroxisome proliferator-responsive element enhancer region of rat acyl-CoA oxidase gene. Biochem. Biophys. Res. Commun., 175, 866-871.
    • (1991) Biochem. Biophys. Res. Commun. , vol.175 , pp. 866-871
    • Osumi, T.1    Wen, J.K.2    Hashimoto, T.3
  • 54
    • 0028276414 scopus 로고
    • Interaction of the Peroxisome Proliferator-Activated Receptor α with the Retinoid X Receptor α unmasks a cryptic peroxisome proliferator response element that overlaps an ARP-1-binding site in the CYP4A6 promoter
    • Palmer, C.N.A., Hsu, M.-H., Muerhoff, A.S., Griffin, K.J. and Johnson, E.F. (1994) Interaction of the Peroxisome Proliferator-Activated Receptor α with the Retinoid X Receptor α unmasks a cryptic peroxisome proliferator response element that overlaps an ARP-1-binding site in the CYP4A6 promoter. J. Biol Chem., 269, 18083-18089.
    • (1994) J. Biol Chem. , vol.269 , pp. 18083-18089
    • Palmer, C.N.A.1    Hsu, M.-H.2    Muerhoff, A.S.3    Griffin, K.J.4    Johnson, E.F.5
  • 55
    • 0022351406 scopus 로고
    • Characterization of triacylglycerol hydrolase activities in isolated myocardial cells from rat heart
    • Ramirez, I., Kryski, A.J., Ben-Zeev, O., Schotz, M.C. and Severson, D.L. (1985) Characterization of triacylglycerol hydrolase activities in isolated myocardial cells from rat heart. Biochem. J., 232, 229-236.
    • (1985) Biochem. J. , vol.232 , pp. 229-236
    • Ramirez, I.1    Kryski, A.J.2    Ben-Zeev, O.3    Schotz, M.C.4    Severson, D.L.5
  • 56
    • 50549202600 scopus 로고
    • The glucose-fatty acid cycle:its role in insulin sensitivity and metabolic disturbances of diabetes mellitus
    • Randle, P.J., Garland, P.B., Hales, C.N. and Newsholme, E.A. (1961) The glucose-fatty acid cycle:its role in insulin sensitivity and metabolic disturbances of diabetes mellitus. Lancet, i, 785-789.
    • (1961) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 57
    • 0028276397 scopus 로고
    • Peroxisome proliferator activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids
    • Rodriguez, J.C., Gil-Gomez, G., Hegardt, F.G. and Haro, D. (1994) Peroxisome proliferator activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids. J. Biol. Chem., 269, 18767-18772.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18767-18772
    • Rodriguez, J.C.1    Gil-Gomez, G.2    Hegardt, F.G.3    Haro, D.4
  • 58
    • 0027256247 scopus 로고
    • Antidiabetic agent pioglitazone enhances adipocyte differentiation of 3T3-F442A cells
    • Sandouk, T., Reda, D. and Hofmann, C. (1993) Antidiabetic agent pioglitazone enhances adipocyte differentiation of 3T3-F442A cells. Am. J. Physiol., 264, C1600-C1608.
    • (1993) Am. J. Physiol. , vol.264
    • Sandouk, T.1    Reda, D.2    Hofmann, C.3
  • 59
    • 0026785388 scopus 로고
    • Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids
    • Schmidt, A., Endo, N., Rutledge, S.J., Vogel, R., Shinar, D. and Rodan, G.A. (1992) Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol. Endocrinol., 6, 1634-1641.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1634-1641
    • Schmidt, A.1    Endo, N.2    Rutledge, S.J.3    Vogel, R.4    Shinar, D.5    Rodan, G.A.6
  • 60
    • 0028071959 scopus 로고
    • The effects of fibrates on lipoprotein and hemostatic risk factors
    • Schonfeld, G. (1994) The effects of fibrates on lipoprotein and hemostatic risk factors. Atherosclerosis, 111, 161-174.
    • (1994) Atherosclerosis , vol.111 , pp. 161-174
    • Schonfeld, G.1
  • 62
    • 0027197802 scopus 로고
    • Developmental extinction of liver lipoprotein lipase mRNA expression might be regulated by an NF-1 like site
    • Schoonjans, K., Staels, B., De Vos, P., Szpirer, J., Szpirer, C., Deeb, S., Verhoeven, G. and Auwerx, J. (1993a) Developmental extinction of liver lipoprotein lipase mRNA expression might be regulated by an NF-1 like site. FEBS Lett., 329, 89-95.
    • (1993) FEBS Lett. , vol.329 , pp. 89-95
    • Schoonjans, K.1    Staels, B.2    De Vos, P.3    Szpirer, J.4    Szpirer, C.5    Deeb, S.6    Verhoeven, G.7    Auwerx, J.8
  • 63
    • 0027292101 scopus 로고
    • Acyl-CoA synthetase mRNA expression is controlled by fibric-acid derivatives, feeding and liver proliferation
    • Schoonjans, K., Staels, B., Grimaldi, P. and Auwerx, J. (1993b) Acyl-CoA synthetase mRNA expression is controlled by fibric-acid derivatives, feeding and liver proliferation. Eur. J. Biochem., 216, 615-622.
    • (1993) Eur. J. Biochem. , vol.216 , pp. 615-622
    • Schoonjans, K.1    Staels, B.2    Grimaldi, P.3    Auwerx, J.4
  • 64
    • 0029144018 scopus 로고
    • Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter
    • Schoonjans, K. et al. (1995) Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter. J. Biol. Chem., 270, 19269-19276.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19269-19276
    • Schoonjans, K.1
  • 65
    • 0027191040 scopus 로고
    • cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor
    • Sher, T., Yi, H.F., McBride, W. and Gonzalez, F.J. (1993) cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor. Biochemistry, 32, 5598-5604.
    • (1993) Biochemistry , vol.32 , pp. 5598-5604
    • Sher, T.1    Yi, H.F.2    McBride, W.3    Gonzalez, F.J.4
  • 66
    • 0021019225 scopus 로고
    • Effects of procetofen on serum lipids and lipoproteins and on post-heparin lipase activities in type II and in type IV hyperlipoproteinemic patients
    • Sommariva, D., Bonfiglioloi, D., Pogliaghi, I., Zanaboni, L. and Balboni, E. (1983) Effects of procetofen on serum lipids and lipoproteins and on post-heparin lipase activities in type II and in type IV hyperlipoproteinemic patients. Curr. Ther. Res., 34, 907-915.
    • (1983) Curr. Ther. Res. , vol.34 , pp. 907-915
    • Sommariva, D.1    Bonfiglioloi, D.2    Pogliaghi, I.3    Zanaboni, L.4    Balboni, E.5
  • 67
    • 0026028217 scopus 로고
    • Antidiabetic AD4743 enhances adipocyte differentiation of 3T3 T mesenchymal stem cells
    • Sparks, R.L., Strauss, E.E., Zygmunt, A.I. and Phelan, T.E. (1991) Antidiabetic AD4743 enhances adipocyte differentiation of 3T3 T mesenchymal stem cells. J. Cell. Phynsiol., 146, 101-109.
    • (1991) J. Cell. Phynsiol. , vol.146 , pp. 101-109
    • Sparks, R.L.1    Strauss, E.E.2    Zygmunt, A.I.3    Phelan, T.E.4
  • 68
    • 0026488464 scopus 로고
    • Perturbation of developmental gene expression in rat liver by fibric acid derivatives: Lipoprotein lipase and alpha-fetoprotein as models
    • Staels, B. and Auwerx, J. (1992) Perturbation of developmental gene expression in rat liver by fibric acid derivatives: lipoprotein lipase and alpha-fetoprotein as models. Development, 115, 1035-1043.
    • (1992) Development , vol.115 , pp. 1035-1043
    • Staels, B.1    Auwerx, J.2
  • 69
    • 0028817459 scopus 로고
    • Fibrates down-regulate apolipoprotein C-III expression independent of induction of peroxisomal acyl co-enzyme A oxidase
    • Staels, B., Vu-Dac, N., Kosykh, V., Saladin, R., Fruchart, J.C., Dallongeville, J. and Auwerx, J. (1995) Fibrates down-regulate apolipoprotein C-III expression independent of induction of peroxisomal acyl co-enzyme A oxidase. J. Clin. Invest., 95, 705-712.
    • (1995) J. Clin. Invest. , vol.95 , pp. 705-712
    • Staels, B.1    Vu-Dac, N.2    Kosykh, V.3    Saladin, R.4    Fruchart, J.C.5    Dallongeville, J.6    Auwerx, J.7
  • 70
    • 0028895004 scopus 로고
    • Thiazolidinediones and fatty acids convert myogenic cells into adipose-like cells
    • Teboul, L., Gaillard, D., Staccini, L., Inadera, H., Amri, E.Z. and Grimaldi, P. (1995) Thiazolidinediones and fatty acids convert myogenic cells into adipose-like cells. J. Biol. Chem., 270, 28183-28137.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28183-128137
    • Teboul, L.1    Gaillard, D.2    Staccini, L.3    Inadera, H.4    Amri, E.Z.5    Grimaldi, P.6
  • 72
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
    • Tontonoz, P., Hu, E. and Spiegelman, B.M. (1994b) Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell, 79, 1147-1156.
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 73
    • 0028988487 scopus 로고
    • PPARγ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
    • Tontonoz, P., Hu, E., Devine, J., Beale, E.G. and Spiegelman, B.M. (1995) PPARγ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol. Cell. Biol., 15, 351-357.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 351-357
    • Tontonoz, P.1    Hu, E.2    Devine, J.3    Beale, E.G.4    Spiegelman, B.M.5
  • 74
    • 0026541591 scopus 로고
    • The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene
    • Tugwood, J.D., Isseman, I., Anderson, R.G., Bundell, K.R., McPheat, W.L. and Green, S. (1992) The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene. EMBO J., 11, 433-439.
    • (1992) EMBO J. , vol.11 , pp. 433-439
    • Tugwood, J.D.1    Isseman, I.2    Anderson, R.G.3    Bundell, K.R.4    McPheat, W.L.5    Green, S.6
  • 75
    • 0028036723 scopus 로고
    • Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element
    • Vu-Dac, N., Schoonjans, K., Laine, B., Fruchart, J.C., Auwerx, J. and Staels, B. (1994) Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element. J. Biol. Chem., 269, 31012-31018.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31012-31018
    • Vu-Dac, N.1    Schoonjans, K.2    Laine, B.3    Fruchart, J.C.4    Auwerx, J.5    Staels, B.6
  • 76
    • 0029119082 scopus 로고
    • Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor
    • Vu-Dae, N., Schoonjans, K., Kosykh, V., Dallongeville, J., Fruchart, J.-C., Staels, B. and Auwerx, J. (1995) Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor. J. Clin. Invest., 96, 741-750.
    • (1995) J. Clin. Invest. , vol.96 , pp. 741-750
    • Vu-Dae, N.1    Schoonjans, K.2    Kosykh, V.3    Dallongeville, J.4    Fruchart, J.-C.5    Staels, B.6    Auwerx, J.7
  • 77
    • 0021954138 scopus 로고
    • Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III
    • Wang, C.-S., McConathy, W.J., Kloer, H.U. and Alaupovic, P. (1985) Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III. J. Clin. Invest., 75, 384-390.
    • (1985) J. Clin. Invest. , vol.75 , pp. 384-390
    • Wang, C.-S.1    McConathy, W.J.2    Kloer, H.U.3    Alaupovic, P.4
  • 78
    • 0024522835 scopus 로고
    • Low-dose cholestipol plus fenofibrate: Effects on plasma lipoproteins, lecithin:cholesterol acyltransferase, and postheparin lipases in familial hypercholesterolemia
    • Weisweiler, P. (1989) Low-dose cholestipol plus fenofibrate: effects on plasma lipoproteins, lecithin:cholesterol acyltransferase, and postheparin lipases in familial hypercholesterolemia. Metabolism, 38, 271-275.
    • (1989) Metabolism , vol.38 , pp. 271-275
    • Weisweiler, P.1
  • 79
    • 0027979778 scopus 로고
    • Establishment and characterization of differentiated nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor α
    • Wu, J.C., Merlino, G. and Fausto, N. (1994) Establishment and characterization of differentiated nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor α. Proc. Natl Acad. Sci. USA, 91, 674-678.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 674-678
    • Wu, J.C.1    Merlino, G.2    Fausto, N.3
  • 81
    • 0026756096 scopus 로고
    • Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase
    • Zhang, B., Marcus, S.L., Sajjadi, F.G., Alvares, K., Reddy, J.K., Subramani, S., Rachubinski, R.A. and Capone, J.P. (1992) Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. Proc. Natl Acad. Sci. USA, 89, 7541-7545.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 7541-7545
    • Zhang, B.1    Marcus, S.L.2    Sajjadi, F.G.3    Alvares, K.4    Reddy, J.K.5    Subramani, S.6    Rachubinski, R.A.7    Capone, J.P.8
  • 82
    • 15844415080 scopus 로고    scopus 로고
    • Down-regulation of the expression of the obese gene by antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice
    • Zhang, B. et al. (1996) Down-regulation of the expression of the obese gene by antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice. J. Biol. Chem., 271, 9455-9459.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9455-9459
    • Zhang, B.1
  • 83
    • 0027749599 scopus 로고
    • Cloning of a new member of the peroxisome proliferator activated receptor gene family from mouse liver
    • Zhu, Y., Alvares, K., Huang, Q., Rao, M.S. and Reddy, J.K. (1993) Cloning of a new member of the peroxisome proliferator activated receptor gene family from mouse liver. J. Biol. Chem., 268, 26817-26820.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26817-26820
    • Zhu, Y.1    Alvares, K.2    Huang, Q.3    Rao, M.S.4    Reddy, J.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.