Tumor necrosis factor α-induced pancreatic β-cell insulin resistance is mediated by nitric oxide and prevented by 15-deoxy-Δ12,14- prostaglandin J2 and aminoguanidine. A role for peroxisome proliferator- activated receptor χ activation and iNOS expression

Journal of Biological Chemistry

Volumn 274, Issue 26, 1999, Pages 18702-18708

  Kwon, Guim ^a   Xu, Guang ^a   Marshall, Connie A ^a   McDaniel, Michael L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGUANIDINE; CYTOKINE; INSULIN; INSULIN RECEPTOR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROSTAGLANDIN J2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL TISSUE; ARTICLE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; INSULIN RESISTANCE; MACROPHAGE ACTIVATION; MALE; METABOLIC INHIBITION; MITOGENESIS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TRANSLATION REGULATION;

ANIMALS; CHROMANS; GUANIDINES; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; ISLETS OF LANGERHANS; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PROSTAGLANDIN D2; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RIBOSOMAL PROTEIN S6 KINASES; THIAZOLES; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0033603337     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.26.18702     Document Type: Article

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