Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 9, 1997, Pages 4318-4323

  Kliewer, Steven A ^a   Sundseth, Scott S ^a   Jones, Stacey A ^a   Brown, Peter J ^a   Wisely, G Bruce ^a   Koble, Cecilia S ^a   Devchand, Pallavi ^b   Wahli, Walter ^b   Willson, Timothy M ^a   Lenhard, James M ^a   Lehmann, Jürgen M ^a  

^a GLAXOSMITHKLINE   (United States)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

fibrate; ligand; nuclear receptor; transcription

Indexed keywords

CELL NUCLEUS RECEPTOR; FIBRIC ACID DERIVATIVE; PEROXISOME PROLIFERATOR;

ARTICLE; GENE EXPRESSION REGULATION; LIGAND BINDING; LIPID METABOLISM; PEROXISOME; PRIORITY JOURNAL; RECEPTOR BINDING; REGULATORY MECHANISM;

ANIMALS; ANTILIPEMIC AGENTS; BINDING, COMPETITIVE; BUTYRATES; EICOSANOIDS; FATTY ACIDS; GENE EXPRESSION REGULATION; HUMANS; LIGANDS; MICE; PHENYLUREA COMPOUNDS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT FUSION PROTEINS; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS; XENOPUS;

EID: 0006132932     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.9.4318     Document Type: Article

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