Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor by phosphorylation of a ligand-independent trans-activating domain

Journal of Biological Chemistry

Volumn 274, Issue 15, 1999, Pages 10505-10510

  Juge Aubry, Cristiana E ^a   Hammar, Eva ^a   Siegrist Kaiser, Catherine ^a   Pernin, Agnès ^a   Takeshita, Akira ^b   Chin, William W ^b   Burger, Albert G ^a   Meier, Christoph A ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; REPRESSOR PROTEIN; TRANSACTIVATOR PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; DISSOCIATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; CONSENSUS SEQUENCE; HUMANS; INSULIN; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PHOSPHORYLATION; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 0033537827     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.15.10505     Document Type: Article

References (32)

1. Kliewer, S. A., Sundseth, S. S., Jones, S. A., Brown, P. J., Wisely, G. B., Koble, C. S., Devchand, P., Wahli, W., Willson, T. M., Lenhard, J. M., and Lehmann, J. M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 4318-4323
2. Wilson, T. M., and Wahli, W. Curr. Opin. Genet. Dev. (1997) 1, 235-241
3. Orti, E., Bodwell, J. E., and Munck, A. (1992) Endocr. Rev. 13, 105-128
4. Kuiper, G. G., and Brinkmann, A. O. (1994) Mol. Cell. Endocrinol. 100, 103-107
5. Kato, S., Endoh, H., Masuhiro, Y., Kitamoto, T., Uchiyama, S., Sasaki, H., Masushige, S., Gotoh, Y., Nishida, E., Kawashima, H., Metzger, D., and Chambon, P. (1995) Science 270, 1491-1494
6. Heery, D. M., Kalkhoven, E., Hoare, S., and Parker, M. G. (1997) Nature 387, 733-736
7. Denner, L. A., Weigel, N. L., Maxwell, B. L., Schrader, W. T., and O'Malley, W. B. (1990) Science 250, 1740-1743
8. Sugawara, A., Yen, P. M., Apriletti, J. W., Ribeiro, R. C. J., Sacks, D. B., Baxter, J. D., and Chin, W. W. (1994) J. Biol. Chem. 269, 433-437
9. Bhat, M. K., Ashizawa, K., and Cheng, S. Y. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7927-7931
10. Shalev, A., Siegrist-Kaiser, C. A., Yen, P. M., Wahli, W., Burger, A. G., Chin, W. W., and Meier, C. A. (1996) Endocrinology 137, 4499-4502
11. Hu, E. D., Kim, J. B., Sarraf, P., and Spiegelman, B. M. (1996) Science 274, 2100-2103
12. Adams, M., Reginato, M. J., Shao, D. L., Lazar, M. A., and Chatterjee, V. K. (1997) J. Biol. Chem. 272, 5128-5132
13. Camp, H. S., and Tafuri, S. R. (1997) J. Biol. Chem. 272, 10811-10816
14. Zhang, B., Berger, J., Zhou, G., Elbrecht, A., Biswas, S., White-Carrington, S., Szalkowski, D., and Moller, D. E. (1996) J. Biol. Chem. 271, 31771-31774
15. Lemberger, T., Braissant, O., Juge-Aubry, C., Keller, H., Saladin, R., Staels, B., Auwerx, J., Burger, A. G., Meier, C. A., and Wahli, W. (1996) Ann. N. Y. Acad. Sci. 804, 231-251
16. Sher, T., Yi, H. F., McBride, O. W., and Gonzalez, F. J. (1993) Biochemistry 32, 5598-5604
17. Juge-Aubry, C., Pernin, A., Favez, T., Burger, A. G., Wahli, W., Meier, C. A., and Desvergne, B. (1997) J. Biol. Chem. 272, 25252-25259
18. Ali, S., Metzger, D., Bornert, J. M., and Chambon, P. (1993) EMBO J. 12, 1153-1160
19. Bunone, G., Briand, P. A., Miksicek, R. J., and Picard, D. (1996) EMBO J. 15, 2174-2183
20. Rochette-Egly, C., Adam, S., Rossignol, M., Egly, J. M., and Chambon, P. (1997) Cell 90, 97-107
21. Hörlein, A., Näär, A. M., Heinzel, T., Torchia, J., Gloss, B., Kurokawa, R., Ryan, A., Kamei, Y., Söderström, M., Glass, C. K., and Rosenfeld, M. G. (1995) Nature 377, 397-404
22. Chen, J. D., and Evans, R. M. (1995) Nature 377, 454-457
23. Meier, C. A., Parkison, C., Chen, A., Ashizawa, K., Meier-Heusler, S. C., Muchmore, P., Cheng, S. Y., and Weintraub, B. D. (1993) J. Clin. Invest. 92, 1986-1993
24. Juge-Aubry, C. E., Gorla-Bajszczak, A., Pernin, A., Lemberger, T., Wahli, W., Burger, A. G., and Meier, C. A. (1995) J. Biol. Chem. 270, 18117-18122
25. Dudley, D. T., Pang, L., Decker, S. J., Bridges, A. J., and Saltiel, A. R. Proc. Natl. Acad. Sci. U. S. A. (1995) 92, 7686-7689
26. Nagpal, S., Friant, S., Nakshatri, H., and Chambon, P. (1993) EMBO J. 12, 2349-2360
27. Glass, C. K., Rose, D. W., and Rosenfeld, M. G. (1997) Curr. Opin. Cell Biol. 9, 222-232
28. Steineger, H. H., Sorensen, H. N., Tugwood, J. D., Skrede, S., Spydevold, O., and Gautvik, K. M. (1994) Eur. J. Biochem. 225, 967-974
29. Ikonen, T., Palvimo, J. J., and Jänne, O. A. (1997) J. Biol. Chem. 272, 29821-29828
30. Onate, S. A., Boonyaratanakornkit, V., Spencer, T. E., Tsai, S. Y., Tsai, M. J., Edwards, D. P., and O'Malley, B. W. (1998) J. Biol. Chem. 273, 12101-12108
31. Zamir, I., Zhang, J. S., and Lazar, M. A. (1997) Genes Dev. 11, 835-846
32. Lavinsky, R. M., Jepsen, K., Heinzel, T., Torchia, J., Mullen, T. M., Schiff, R., Del-Rio, A. L., Ricote, M., Ngo, S., Gemsch, J., Hilsenbeck, S. G., Osborne, C. K., Glass, C. K., Rosenfeld, M. G., and Rose, D. W. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 2920-2925