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Volumn 3, Issue , 2008, Pages 523-555

Airway smooth muscle in asthma

Author keywords

Cytokines; Hyperplasia; Hypertrophy; Inflammation; Remodeling

Indexed keywords

AIRWAY OBSTRUCTION; ASTHMA; HUMAN; IMMUNOMODULATION; INFLAMMATION; PATHOGENESIS; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; REVIEW; SMOOTH MUSCLE;

EID: 41749095876     PISSN: 15534006     EISSN: 15534014     Source Type: Book Series    
DOI: 10.1146/annurev.pathmechdis.1.110304.100213     Document Type: Review
Times cited : (70)

References (243)
  • 1
    • 0021721214 scopus 로고
    • The role of vascular smooth muscle cells in experimental autoimmune vasculitis. I. The initiation of delayed type hypersensitivity angiitis
    • Moyer CF, Reinisch CL. 1984. The role of vascular smooth muscle cells in experimental autoimmune vasculitis. I. The initiation of delayed type hypersensitivity angiitis. Am. J. Pathol. 117:380-90
    • (1984) Am. J. Pathol , vol.117 , pp. 380-390
    • Moyer, C.F.1    Reinisch, C.L.2
  • 3
    • 0032991806 scopus 로고    scopus 로고
    • Constitutive and cytokine-stimulated expression of eotaxin by human airway smooth muscle cells
    • Ghaffar O, Hamid Q, Renzi PM, Allakhverdi Z, Molet S, et al. 1999. Constitutive and cytokine-stimulated expression of eotaxin by human airway smooth muscle cells. Am. J. Respir. Crit. Care Med. 159:1933-42
    • (1999) Am. J. Respir. Crit. Care Med , vol.159 , pp. 1933-1942
    • Ghaffar, O.1    Hamid, Q.2    Renzi, P.M.3    Allakhverdi, Z.4    Molet, S.5
  • 5
    • 0032545433 scopus 로고    scopus 로고
    • Requirement for IL-13 independently of IL-4 in experimental asthma
    • Grunig G, Warnock M, Wakil AE, Venkayya R, Brombacher F, et al. 1998. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 282:2261-63
    • (1998) Science , vol.282 , pp. 2261-2263
    • Grunig, G.1    Warnock, M.2    Wakil, A.E.3    Venkayya, R.4    Brombacher, F.5
  • 6
    • 0036344597 scopus 로고    scopus 로고
    • Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma
    • Kuperman DA, Huang X, Koth LL, Chang GH, Dolganov GM, et al. 2002. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat. Med. 8:885-89
    • (2002) Nat. Med , vol.8 , pp. 885-889
    • Kuperman, D.A.1    Huang, X.2    Koth, L.L.3    Chang, G.H.4    Dolganov, G.M.5
  • 7
    • 0033104696 scopus 로고    scopus 로고
    • Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells
    • Li L, Xia Y, Nguyen A, Lai YH, Feng L, et al. 1999. Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. J. Immunol. 162:2477-87
    • (1999) J. Immunol , vol.162 , pp. 2477-2487
    • Li, L.1    Xia, Y.2    Nguyen, A.3    Lai, Y.H.4    Feng, L.5
  • 8
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, et al. 1999. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J. Clin. Invest. 103:779-88
    • (1999) J. Clin. Invest , vol.103 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5
  • 10
    • 4043140732 scopus 로고    scopus 로고
    • IL-9-mediated induction of eotaxin1/CCL11 in human airway smooth muscle cells
    • Gounni AS, Hamid Q, Rahman SM, Hoeck J, Yang J, Shan L. 2004. IL-9-mediated induction of eotaxin1/CCL11 in human airway smooth muscle cells. J. Immunol. 173:2771-79
    • (2004) J. Immunol , vol.173 , pp. 2771-2779
    • Gounni, A.S.1    Hamid, Q.2    Rahman, S.M.3    Hoeck, J.4    Yang, J.5    Shan, L.6
  • 11
    • 4444315075 scopus 로고    scopus 로고
    • Effects of interleukin-1β, interleukin-13 and transforming growth factor-β on gene expression in human airway smooth muscle using gene microarrays
    • Jarai G, Sukkar M, Garrett S, Duroudier N, Westwick J, et al. 2004. Effects of interleukin-1β, interleukin-13 and transforming growth factor-β on gene expression in human airway smooth muscle using gene microarrays. Eur. J. Pharmacol. 497:255-65
    • (2004) Eur. J. Pharmacol , vol.497 , pp. 255-265
    • Jarai, G.1    Sukkar, M.2    Garrett, S.3    Duroudier, N.4    Westwick, J.5
  • 13
    • 13244279654 scopus 로고    scopus 로고
    • Differential regulation of chemokine expression by peroxisome proliferator-activated receptor γ agonists: Interactions with glucocorticoids and β2-agonists
    • Nie M, Corbett L, Knox AJ, Pang L. 2005. Differential regulation of chemokine expression by peroxisome proliferator-activated receptor γ agonists: interactions with glucocorticoids and β2-agonists. J. Biol. Chem. 280:2550-61
    • (2005) J. Biol. Chem , vol.280 , pp. 2550-2561
    • Nie, M.1    Corbett, L.2    Knox, A.J.3    Pang, L.4
  • 14
    • 1442325348 scopus 로고    scopus 로고
    • Signaling pathways regulating interleukin-13-stimulated chemokine release from airway smooth muscle
    • Peng Q, Matsuda T, Hirst SJ. 2004. Signaling pathways regulating interleukin-13-stimulated chemokine release from airway smooth muscle. Am. J. Respir. Crit. Care Med. 169:596-603
    • (2004) Am. J. Respir. Crit. Care Med , vol.169 , pp. 596-603
    • Peng, Q.1    Matsuda, T.2    Hirst, S.J.3
  • 15
    • 4944253264 scopus 로고    scopus 로고
    • TGF-β differentially regulates TH2 cytokine-induced eotaxin and eotaxin-3 release by human airway smooth muscle cells
    • Zuyderduyn S, Hiemstra PS, Rabe KF. 2004. TGF-β differentially regulates TH2 cytokine-induced eotaxin and eotaxin-3 release by human airway smooth muscle cells. J. Allergy Clin. Immunol. 114:791-98
    • (2004) J. Allergy Clin. Immunol , vol.114 , pp. 791-798
    • Zuyderduyn, S.1    Hiemstra, P.S.2    Rabe, K.F.3
  • 17
    • 16544373983 scopus 로고    scopus 로고
    • Fractalkine/CX3CL1 production by human airway smooth muscle cells: Induction by IFN-γ and TNF-α and regulation by TGF-β and corticosteroids
    • Sukkar MB, Issa R, Xie S, Oltmanns U, Newton R, Chung KF. 2004. Fractalkine/CX3CL1 production by human airway smooth muscle cells: induction by IFN-γ and TNF-α and regulation by TGF-β and corticosteroids. Am. J. Physiol. Lung Cell Mol. Physiol. 287:L1230-40
    • (2004) Am. J. Physiol. Lung Cell Mol. Physiol , vol.287
    • Sukkar, M.B.1    Issa, R.2    Xie, S.3    Oltmanns, U.4    Newton, R.5    Chung, K.F.6
  • 19
    • 0032699292 scopus 로고    scopus 로고
    • Autocrine interaction between IL-5 and IL-1β mediates altered responsiveness of atopic asthmatic sensitized airway smooth muscle
    • Hakonarson H, Masked N, Carter C, Chuang S, Grunstein MM. 1999. Autocrine interaction between IL-5 and IL-1β mediates altered responsiveness of atopic asthmatic sensitized airway smooth muscle. J. Clin. Invest. 104:657-67
    • (1999) J. Clin. Invest , vol.104 , pp. 657-667
    • Hakonarson, H.1    Masked, N.2    Carter, C.3    Chuang, S.4    Grunstein, M.M.5
  • 20
    • 6444237318 scopus 로고    scopus 로고
    • Role and regulation of interleukin-1 molecules in pro-asthmatic sensitised airway smooth muscle
    • Whelan R, Kim C, Chen M, Leiter J, Grunstein MM, Hakonarson H. 2004. Role and regulation of interleukin-1 molecules in pro-asthmatic sensitised airway smooth muscle. Eur. Respir. J. 24:559-67
    • (2004) Eur. Respir. J , vol.24 , pp. 559-567
    • Whelan, R.1    Kim, C.2    Chen, M.3    Leiter, J.4    Grunstein, M.M.5    Hakonarson, H.6
  • 21
    • 0031039525 scopus 로고    scopus 로고
    • Release of granulocyte-macrophage colony stimulating factor by human cultured airway smooth muscle cells: Suppression by dexamethasone
    • Saunders MA, Mitchell JA, Seldon PM, Yacoub MH, Barnes PJ, et al. 1997. Release of granulocyte-macrophage colony stimulating factor by human cultured airway smooth muscle cells: suppression by dexamethasone. Br. J. Pharmacol. 120:545-46
    • (1997) Br. J. Pharmacol , vol.120 , pp. 545-546
    • Saunders, M.A.1    Mitchell, J.A.2    Seldon, P.M.3    Yacoub, M.H.4    Barnes, P.J.5
  • 22
    • 33745408133 scopus 로고    scopus 로고
    • Cytokine- and virus-stimulated airway smooth muscle cells produce IL-11 and other IL-6-type cytokines
    • Elias JA, Wu Y, Zheng T, Panettieri R. 1997. Cytokine- and virus-stimulated airway smooth muscle cells produce IL-11 and other IL-6-type cytokines. Am. J. Physiol. 273:L648-55
    • (1997) Am. J. Physiol , vol.273
    • Elias, J.A.1    Wu, Y.2    Zheng, T.3    Panettieri, R.4
  • 25
    • 23444446772 scopus 로고    scopus 로고
    • Human airway smooth muscle cells express the high affinity receptor for IgE (FcεRI): A critical role of Fc epsilon RI in human airway smooth muscle cell function
    • Gounni AS, Wellemans V, Yang J, Bellesort F, Kassiri K, et al. 2005. Human airway smooth muscle cells express the high affinity receptor for IgE (FcεRI): a critical role of Fc epsilon RI in human airway smooth muscle cell function. J. Immunol. 175:2613-21
    • (2005) J. Immunol , vol.175 , pp. 2613-2621
    • Gounni, A.S.1    Wellemans, V.2    Yang, J.3    Bellesort, F.4    Kassiri, K.5
  • 26
    • 33748424832 scopus 로고    scopus 로고
    • The high-affinity IgE receptor (FcεRI): A critical regulator of airway smooth muscle cells?
    • Gounni AS. 2006. The high-affinity IgE receptor (FcεRI): a critical regulator of airway smooth muscle cells? Am. J. Physiol. Lung Cell Mol. Physiol. 291:L312-21
    • (2006) Am. J. Physiol. Lung Cell Mol. Physiol , vol.291
    • Gounni, A.S.1
  • 27
    • 0032846886 scopus 로고    scopus 로고
    • Altered expression and action of the low-affinity IgE receptor FcεRII (CD23) in asthmatic airway smooth muscle
    • Hakonarson H, Carter C, Kim C, Grunstein MM. 1999. Altered expression and action of the low-affinity IgE receptor FcεRII (CD23) in asthmatic airway smooth muscle. J. Allergy Clin. Immunol. 104:575-84
    • (1999) J. Allergy Clin. Immunol , vol.104 , pp. 575-584
    • Hakonarson, H.1    Carter, C.2    Kim, C.3    Grunstein, M.M.4
  • 28
    • 0028917927 scopus 로고
    • Activation of cAMP-dependent pathways in human airway smooth muscle cells inhibits TNF-α-induced ICAM-1 and VCAM-1 expression and T lymphocyte adhesion
    • Panettieri RA Jr, Lazaar AL, Pure E, Albelda SM. 1995. Activation of cAMP-dependent pathways in human airway smooth muscle cells inhibits TNF-α-induced ICAM-1 and VCAM-1 expression and T lymphocyte adhesion. J. Immunol. 154:2358-65
    • (1995) J. Immunol , vol.154 , pp. 2358-2365
    • Panettieri Jr, R.A.1    Lazaar, A.L.2    Pure, E.3    Albelda, S.M.4
  • 29
    • 0027994066 scopus 로고
    • T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis
    • Lazaar AL, Albelda SM, Pilewski JM, Brennan B, Pure E, Panettieri RA Jr. 1994. T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis. J. Exp. Med. 180:807-16
    • (1994) J. Exp. Med , vol.180 , pp. 807-816
    • Lazaar, A.L.1    Albelda, S.M.2    Pilewski, J.M.3    Brennan, B.4    Pure, E.5    Panettieri Jr., R.A.6
  • 30
    • 25444487989 scopus 로고    scopus 로고
    • The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells
    • Syed F, Panettieri RA Jr, Tliba O, Huang C, Li K, et al. 2005. The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells. Respir. Res. 6:9
    • (2005) Respir. Res , vol.6 , pp. 9
    • Syed, F.1    Panettieri Jr, R.A.2    Tliba, O.3    Huang, C.4    Li, K.5
  • 31
    • 12144275863 scopus 로고    scopus 로고
    • Involvement of p42/p44 MAPK, p38 MAPK, JNK, and NF-κB in IL-1β-induced VCAM-1 expression in human tracheal smooth muscle cells
    • Wang CC, Lin WN, Lee CW, Lin CC, Luo SF, et al. 2005. Involvement of p42/p44 MAPK, p38 MAPK, JNK, and NF-κB in IL-1β-induced VCAM-1 expression in human tracheal smooth muscle cells. Am. J. Physiol. Lung Cell Mol. Physiol. 288:L227-37
    • (2005) Am. J. Physiol. Lung Cell Mol. Physiol , vol.288
    • Wang, C.C.1    Lin, W.N.2    Lee, C.W.3    Lin, C.C.4    Luo, S.F.5
  • 33
    • 0035164213 scopus 로고    scopus 로고
    • VCAM-1 activates phosphatidylinositol 3-kinase and induces p120Cbl phosphorylation in human airway smooth muscle cells
    • Lazaar AL, Krymskaya VP, Das SK. 2001. VCAM-1 activates phosphatidylinositol 3-kinase and induces p120Cbl phosphorylation in human airway smooth muscle cells. J. Immunol. 166:155-61
    • (2001) J. Immunol , vol.166 , pp. 155-161
    • Lazaar, A.L.1    Krymskaya, V.P.2    Das, S.K.3
  • 34
    • 0346749458 scopus 로고    scopus 로고
    • Tumor necrosis factor α modulates airway smooth muscle function via the autocrine action of interferon β
    • Tliba O, Tliba S, Da Huang C, Hoffman RK, DeLong P, et al. 2003. Tumor necrosis factor α modulates airway smooth muscle function via the autocrine action of interferon β. J. Biol. Chem. 278:50615-23
    • (2003) J. Biol. Chem , vol.278 , pp. 50615-50623
    • Tliba, O.1    Tliba, S.2    Da Huang, C.3    Hoffman, R.K.4    DeLong, P.5
  • 35
    • 0032090939 scopus 로고    scopus 로고
    • Angiotensin II induces hypertrophy of human airway smooth muscle cells: Expression of transcription factors and transforming growth factor-β1
    • McKay S, de Jongste JC, Saxena PR, Sharma HS. 1998. Angiotensin II induces hypertrophy of human airway smooth muscle cells: expression of transcription factors and transforming growth factor-β1. Am. J. Respir. Cell Mol. Biol. 18:823-33
    • (1998) Am. J. Respir. Cell Mol. Biol , vol.18 , pp. 823-833
    • McKay, S.1    de Jongste, J.C.2    Saxena, P.R.3    Sharma, H.S.4
  • 36
    • 0027330329 scopus 로고
    • Interleukin-1 β stimulates the proliferation of cultured airway smooth muscle cells via platelet-derived growth factor
    • De S, Zelazny ET, Souhrada JF, Souhrada M. 1993. Interleukin-1 β stimulates the proliferation of cultured airway smooth muscle cells via platelet-derived growth factor. Am. J. Respir. Cell Mol. Biol. 9:645-51
    • (1993) Am. J. Respir. Cell Mol. Biol , vol.9 , pp. 645-651
    • De, S.1    Zelazny, E.T.2    Souhrada, J.F.3    Souhrada, M.4
  • 37
    • 0038518094 scopus 로고    scopus 로고
    • TH2 cytokine-enhanced and TGF-β-enhanced vascular endothelial growth factor production by cultured human airway smooth muscle cells is attenuated by IFN-γ and corticosteroids
    • Wen FQ, Liu X, Manda W, Terasaki Y, Kobayashi T, et al. 2003. TH2 cytokine-enhanced and TGF-β-enhanced vascular endothelial growth factor production by cultured human airway smooth muscle cells is attenuated by IFN-γ and corticosteroids. J. Allergy Clin. Immunol. 111:1307-18
    • (2003) J. Allergy Clin. Immunol , vol.111 , pp. 1307-1318
    • Wen, F.Q.1    Liu, X.2    Manda, W.3    Terasaki, Y.4    Kobayashi, T.5
  • 39
    • 0035158686 scopus 로고    scopus 로고
    • Human airway smooth muscle cells secrete vascular endothelial growth factor: Up-regulation by bradykinin via a protein kinase C and prostanoid-dependent mechanism
    • Knox AJ, Corbett L, Stocks J, Holland E, Zhu YM, Pang L. 2001. Human airway smooth muscle cells secrete vascular endothelial growth factor: up-regulation by bradykinin via a protein kinase C and prostanoid-dependent mechanism. FASEB J. 15:2480-88
    • (2001) FASEB J , vol.15 , pp. 2480-2488
    • Knox, A.J.1    Corbett, L.2    Stocks, J.3    Holland, E.4    Zhu, Y.M.5    Pang, L.6
  • 40
  • 42
    • 0022978869 scopus 로고
    • In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, β-adrenoeeptor agonists and theophylline
    • Goldie RG, Spina D, Henry PJ, Lulich KM, Paterson JW. 1986. In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, β-adrenoeeptor agonists and theophylline. Br. J. Clin. Pharmacol. 22:669-76
    • (1986) Br. J. Clin. Pharmacol , vol.22 , pp. 669-676
    • Goldie, R.G.1    Spina, D.2    Henry, P.J.3    Lulich, K.M.4    Paterson, J.W.5
  • 43
    • 0024123412 scopus 로고
    • Responsiveness of bronchial smooth muscle from asthmatic patients to relaxant and contractile agonists
    • Whicker SD, Armour CL, Black JL. 1988. Responsiveness of bronchial smooth muscle from asthmatic patients to relaxant and contractile agonists. Pulmonary Pharmacol. 1:25-31
    • (1988) Pulmonary Pharmacol , vol.1 , pp. 25-31
    • Whicker, S.D.1    Armour, C.L.2    Black, J.L.3
  • 44
    • 0025977594 scopus 로고
    • Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus
    • Bai TR. 1991. Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus. Am. Rev. Respir. Dis. 143:441-43
    • (1991) Am. Rev. Respir. Dis , vol.143 , pp. 441-443
    • Bai, T.R.1
  • 45
    • 0032903716 scopus 로고    scopus 로고
    • Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: An in vitro coculture model of airway remodeling in asthma
    • Zhang S, Smartt H, Holgate ST, Roche WR. 1999. Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro coculture model of airway remodeling in asthma. Lab. Invest. 79:395-405
    • (1999) Lab. Invest , vol.79 , pp. 395-405
    • Zhang, S.1    Smartt, H.2    Holgate, S.T.3    Roche, W.R.4
  • 46
  • 48
    • 0024828192 scopus 로고
    • Bronchial biopsies in asthma: An ultrastructural, quantitiative study and correlation with hyperreactivity
    • Jeffery PK, Wardlaw AJ, Nelson FC, Collins JV, Kay AB. 1989. Bronchial biopsies in asthma: an ultrastructural, quantitiative study and correlation with hyperreactivity. Am. Rev. Respir. Dis. 140:1745-53
    • (1989) Am. Rev. Respir. Dis , vol.140 , pp. 1745-1753
    • Jeffery, P.K.1    Wardlaw, A.J.2    Nelson, F.C.3    Collins, J.V.4    Kay, A.B.5
  • 49
    • 0030267704 scopus 로고    scopus 로고
    • Expression of laminins in the airways in various types of asthmatic patients: A morphometric study
    • Altraja A, Laitinen A, Virtanen I, Kampe M, Simonsson BG, et al. 1996. Expression of laminins in the airways in various types of asthmatic patients: a morphometric study. Am. J. Respir. Cell Mol. Biol. 15:482-88
    • (1996) Am. J. Respir. Cell Mol. Biol , vol.15 , pp. 482-488
    • Altraja, A.1    Laitinen, A.2    Virtanen, I.3    Kampe, M.4    Simonsson, B.G.5
  • 52
    • 8544230635 scopus 로고    scopus 로고
    • Transforming growth factor-β expression in mucosal biopsies in asthma and chronic bronchitis
    • Vignola AM, Chanez P, Chiappara G, Merendino A, Pace E, et al. 1997. Transforming growth factor-β expression in mucosal biopsies in asthma and chronic bronchitis. Am. J. Respir. Crit. Care Med. 156:591-99
    • (1997) Am. J. Respir. Crit. Care Med , vol.156 , pp. 591-599
    • Vignola, A.M.1    Chanez, P.2    Chiappara, G.3    Merendino, A.4    Pace, E.5
  • 54
    • 0038544594 scopus 로고    scopus 로고
    • Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma
    • Schmidt M, Sun G, Stacey MA, Mori L, Mattoli S. 2003. Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma. J. Immunol. 171:380-89
    • (2003) J. Immunol , vol.171 , pp. 380-389
    • Schmidt, M.1    Sun, G.2    Stacey, M.A.3    Mori, L.4    Mattoli, S.5
  • 55
    • 8444250651 scopus 로고    scopus 로고
    • Presence of activated mobile fibroblasts in bronchoalveolar lavage from patients with mild asthma
    • Larsen K, Tufvesson E, Malmstrom J, Morgelin M, Wildt M, et al. 2004. Presence of activated mobile fibroblasts in bronchoalveolar lavage from patients with mild asthma. Am. J. Respir. Crit. Care Med. 170:1049-56
    • (2004) Am. J. Respir. Crit. Care Med , vol.170 , pp. 1049-1056
    • Larsen, K.1    Tufvesson, E.2    Malmstrom, J.3    Morgelin, M.4    Wildt, M.5
  • 56
    • 0026563614 scopus 로고
    • Characteristics of the inflammation in biopsies from large airways of subjects with asthma and subjects with chronic airflow limitation
    • Ollerenshaw SL, Woolcock AJ. 1992. Characteristics of the inflammation in biopsies from large airways of subjects with asthma and subjects with chronic airflow limitation. Am. Rev. Respir. Dis. 145:922-27
    • (1992) Am. Rev. Respir. Dis , vol.145 , pp. 922-927
    • Ollerenshaw, S.L.1    Woolcock, A.J.2
  • 58
    • 0030236307 scopus 로고    scopus 로고
    • Transforming growth factor β 1 (TGF β1) gene expression by eosinophils in asthmatic airway inflammation
    • Ohno I, Nitta Y, Yamauchi K, Hoshi H, Honma M, et al. 1996. Transforming growth factor β 1 (TGF β1) gene expression by eosinophils in asthmatic airway inflammation. Am. J. Respir. Cell Mol. Biol. 15:404-9
    • (1996) Am. J. Respir. Cell Mol. Biol , vol.15 , pp. 404-409
    • Ohno, I.1    Nitta, Y.2    Yamauchi, K.3    Hoshi, H.4    Honma, M.5
  • 59
    • 0008249094 scopus 로고    scopus 로고
    • Balance between proinflammatory cytokines and their inhibitors in bronchial lavage from patients with status asthmaticus
    • Tillie-Leblond I, Pugin J, Marquette C-H, Lamblin C, Saulnier F, et al. 1999. Balance between proinflammatory cytokines and their inhibitors in bronchial lavage from patients with status asthmaticus. Am. J. Respir. Crit. Care Med. 159:487-94
    • (1999) Am. J. Respir. Crit. Care Med , vol.159 , pp. 487-494
    • Tillie-Leblond, I.1    Pugin, J.2    Marquette, C.-H.3    Lamblin, C.4    Saulnier, F.5
  • 60
    • 0036279977 scopus 로고    scopus 로고
    • Increases in collagen type I collagen synthesis in asthma: The role of eosinophils and transforming growth factor-β
    • Nomura A, Uchida Y, Sakamoto T, Ishii Y, Masuyama K, et al. 2002. Increases in collagen type I collagen synthesis in asthma: the role of eosinophils and transforming growth factor-β. Clin. Exp. Allergy 32:860-65
    • (2002) Clin. Exp. Allergy , vol.32 , pp. 860-865
    • Nomura, A.1    Uchida, Y.2    Sakamoto, T.3    Ishii, Y.4    Masuyama, K.5
  • 61
    • 0014491275 scopus 로고
    • A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis and in emphysema
    • Dunhill MS, Massarella GR, Anderson JA. 1971. A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis and in emphysema. Thorax 24:176
    • (1971) Thorax , vol.24 , pp. 176
    • Dunhill, M.S.1    Massarella, G.R.2    Anderson, J.A.3
  • 62
    • 0015121553 scopus 로고
    • Muscle and mucous gland size in the major bronchi of patients with chronic bronchitis, asthma, and asthmatic bronchitis
    • Takizawa T, Thurlbeck WM. 1971. Muscle and mucous gland size in the major bronchi of patients with chronic bronchitis, asthma, and asthmatic bronchitis. Am. Rev. Respir. Dis. 104:331-36
    • (1971) Am. Rev. Respir. Dis , vol.104 , pp. 331-336
    • Takizawa, T.1    Thurlbeck, W.M.2
  • 63
    • 0015911409 scopus 로고
    • Hyperplasia of bronchial smooth muscle in asthma
    • Heard BE, Hossain S. 1973. Hyperplasia of bronchial smooth muscle in asthma. J. Pathol. 110:319-32
    • (1973) J. Pathol , vol.110 , pp. 319-332
    • Heard, B.E.1    Hossain, S.2
  • 64
    • 0021210951 scopus 로고
    • Quantitative structural alterations in long-standing allergic asthma
    • Sobonya RE. 1984. Quantitative structural alterations in long-standing allergic asthma. Am. Rev. Respirat. Dis. 130:289-92
    • (1984) Am. Rev. Respirat. Dis , vol.130 , pp. 289-292
    • Sobonya, R.E.1
  • 66
    • 0026026853 scopus 로고
    • Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma
    • Saetta M, Di Stefano A, Rosina C, Thiene G, Fabbri LM. 1991. Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma. Am. Rev. Respir. Dis. 143:138-43
    • (1991) Am. Rev. Respir. Dis , vol.143 , pp. 138-143
    • Saetta, M.1    Di Stefano, A.2    Rosina, C.3    Thiene, G.4    Fabbri, L.M.5
  • 67
    • 0027181166 scopus 로고
    • Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. A 3-D morphometric study
    • Ebina M, Takahashi T, Chiba T, Motomiya M. 1993. Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. A 3-D morphometric study. Am. Rev. Respir. Dis. 148:720-26
    • (1993) Am. Rev. Respir. Dis , vol.148 , pp. 720-726
    • Ebina, M.1    Takahashi, T.2    Chiba, T.3    Motomiya, M.4
  • 68
    • 0032875377 scopus 로고    scopus 로고
    • Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
    • Wenzel SE, Schwartz LB, Langmack EL, Halliday JL, Trudeau JB, et al. 1999. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am. J. Respir. Crit. Care Med. 160:1001-8
    • (1999) Am. J. Respir. Crit. Care Med , vol.160 , pp. 1001-1008
    • Wenzel, S.E.1    Schwartz, L.B.2    Langmack, E.L.3    Halliday, J.L.4    Trudeau, J.B.5
  • 69
    • 0027404742 scopus 로고
    • The structure of large and small airways in nonfatal and fatal asthma
    • Carroll N, Elliot J, Morton A, James A. 1993. The structure of large and small airways in nonfatal and fatal asthma. Am. Rev. Respir. Dis. 147:405-10
    • (1993) Am. Rev. Respir. Dis , vol.147 , pp. 405-410
    • Carroll, N.1    Elliot, J.2    Morton, A.3    James, A.4
  • 71
    • 11144358047 scopus 로고    scopus 로고
    • Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression
    • Woodraff PG, Dolganov GM, Ferrando RE, Donnelly S, Hays SR, et al. 2004. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J. Respir. Crit. Care Med. 169:1001-6
    • (2004) Am J. Respir. Crit. Care Med , vol.169 , pp. 1001-1006
    • Woodraff, P.G.1    Dolganov, G.M.2    Ferrando, R.E.3    Donnelly, S.4    Hays, S.R.5
  • 73
    • 0030641095 scopus 로고    scopus 로고
    • TGF-β 1 modulates human airway smooth-muscle cell proliferation induced by mitogens
    • Cohen MD, Ciocca V, Panettieri RA Jr. 1997. TGF-β 1 modulates human airway smooth-muscle cell proliferation induced by mitogens. Am. J. Respir. Cell Mol. Biol. 16:85-90
    • (1997) Am. J. Respir. Cell Mol. Biol , vol.16 , pp. 85-90
    • Cohen, M.D.1    Ciocca, V.2    Panettieri Jr., R.A.3
  • 75
    • 34447525369 scopus 로고    scopus 로고
    • Nox4 mediates TGF-β1-induced retinoblastoma protein phosphorylation, proliferation and hypertrophy in human airway smooth muscle cells
    • Sturrock A, Huecksteadt TP, Norman K, Sanders KA, Murphy TM, et al. 2007. Nox4 mediates TGF-β1-induced retinoblastoma protein phosphorylation, proliferation and hypertrophy in human airway smooth muscle cells. Am. J. Physiol. Lung Cell Mol. Physiol. 292:L1543-55
    • (2007) Am. J. Physiol. Lung Cell Mol. Physiol , vol.292
    • Sturrock, A.1    Huecksteadt, T.P.2    Norman, K.3    Sanders, K.A.4    Murphy, T.M.5
  • 77
    • 0027318687 scopus 로고
    • Functional significance of increased airway smooth muscle in asthma and COPD
    • Lambert RK, Wiggs BR, Kuwano K, Hogg JC, Pare PD. 1993. Functional significance of increased airway smooth muscle in asthma and COPD. J. Appl. Physiol. 74:2771-81
    • (1993) J. Appl. Physiol , vol.74 , pp. 2771-2781
    • Lambert, R.K.1    Wiggs, B.R.2    Kuwano, K.3    Hogg, J.C.4    Pare, P.D.5
  • 79
    • 0030933944 scopus 로고    scopus 로고
    • Airway remodeling is a distinctive feature of asthma and is related to severity of disease
    • Chetta A, Foresi A, Del Donno M, Bertorelli G, Pesci A, Olivieri D. 1997. Airway remodeling is a distinctive feature of asthma and is related to severity of disease. Chest 111:852-57
    • (1997) Chest , vol.111 , pp. 852-857
    • Chetta, A.1    Foresi, A.2    Del Donno, M.3    Bertorelli, G.4    Pesci, A.5    Olivieri, D.6
  • 80
    • 0030814301 scopus 로고    scopus 로고
    • Bronchial subepitheial fibrosis correlates with airway responsiveness to methacholine
    • Boulet L-P, Laviolette M, Turcotte H, Cartier A, Dugas M, et al. 1997. Bronchial subepitheial fibrosis correlates with airway responsiveness to methacholine. Chest 112:45-52
    • (1997) Chest , vol.112 , pp. 45-52
    • Boulet, L.-P.1    Laviolette, M.2    Turcotte, H.3    Cartier, A.4    Dugas, M.5
  • 81
    • 0030958324 scopus 로고    scopus 로고
    • Effect of short-term treatment with low-dose inhaled fluticasone proprionate on airway inflammation and remodelling in mild asthma: A placebo controlled study
    • Olivieri D, Chetta A, DD M, Bertorelli G, Casalina A, et al. 1997. Effect of short-term treatment with low-dose inhaled fluticasone proprionate on airway inflammation and remodelling in mild asthma: a placebo controlled study. Am. J. Respir. Crit. Care Med. 155:1864-71
    • (1997) Am. J. Respir. Crit. Care Med , vol.155 , pp. 1864-1871
    • Olivieri, D.1    Chetta, A.2    DD, M.3    Bertorelli, G.4    Casalina, A.5
  • 84
    • 0021319905 scopus 로고
    • Asthma and irreversible airflow obstruction
    • Brown PJ, Greville HW, Finucane KE. 1984. Asthma and irreversible airflow obstruction. Thorax 39:131-36
    • (1984) Thorax , vol.39 , pp. 131-136
    • Brown, P.J.1    Greville, H.W.2    Finucane, K.E.3
  • 85
    • 0026059504 scopus 로고
    • Asthma in the elderly: A comparison between patients with recently acquired and long-standing disease
    • Braman SS, Kaemmerlen JT, Davis SM. 1991. Asthma in the elderly: a comparison between patients with recently acquired and long-standing disease. Am. Rev. Respir. Dis. 143:336-40
    • (1991) Am. Rev. Respir. Dis , vol.143 , pp. 336-340
    • Braman, S.S.1    Kaemmerlen, J.T.2    Davis, S.M.3
  • 86
    • 0028855082 scopus 로고
    • Role of MAP kinase activation in bovine tracheal smooth muscle mitogenesis
    • Kelleher MD, Abe MK, Chao TS, Jain M, Green JM, et al. 1995. Role of MAP kinase activation in bovine tracheal smooth muscle mitogenesis. Am. J. Physiol. 268:L894-901
    • (1995) Am. J. Physiol , vol.268
    • Kelleher, M.D.1    Abe, M.K.2    Chao, T.S.3    Jain, M.4    Green, J.M.5
  • 87
    • 0029915964 scopus 로고    scopus 로고
    • PDGF isoform-induced proliferation and receptor expression in human cultured airway smooth muscle cells
    • Hirst SJ, Barnes PJ, Twort CH. 1996. PDGF isoform-induced proliferation and receptor expression in human cultured airway smooth muscle cells. Am. J. Physiol. 270:L415-28
    • (1996) Am. J. Physiol , vol.270
    • Hirst, S.J.1    Barnes, P.J.2    Twort, C.H.3
  • 88
    • 0027023203 scopus 로고
    • Quantifying proliferation of cultured human and rabbit airway smooth muscle cells in response to serum and platelet-derived growth factor
    • Hirst SJ, Barnes PJ, Twort CH. 1992. Quantifying proliferation of cultured human and rabbit airway smooth muscle cells in response to serum and platelet-derived growth factor. Am. J Respir. Cell Mol. Biol. 7:574-81
    • (1992) Am. J Respir. Cell Mol. Biol , vol.7 , pp. 574-581
    • Hirst, S.J.1    Barnes, P.J.2    Twort, C.H.3
  • 91
    • 0028279313 scopus 로고
    • Mitogenic actions of endothelin-1 and epidermal growth factor in cultured airway smooth muscle
    • Stewart AG, Grigoriadis G, Harris T. 1994. Mitogenic actions of endothelin-1 and epidermal growth factor in cultured airway smooth muscle. Clin. Exp. Pharmacol. Physiol. 21:277-85
    • (1994) Clin. Exp. Pharmacol. Physiol , vol.21 , pp. 277-285
    • Stewart, A.G.1    Grigoriadis, G.2    Harris, T.3
  • 92
    • 0029356279 scopus 로고
    • α-Thrombin increases cytosolic calcium and induces human airway smooth muscle cell proliferation
    • Panettieri RA Jr, Hall IP, Maki CS, Murray RK. 1995. α-Thrombin increases cytosolic calcium and induces human airway smooth muscle cell proliferation. Am. J. Respir. Cell Mol. Biol. 13:205-16
    • (1995) Am. J. Respir. Cell Mol. Biol , vol.13 , pp. 205-216
    • Panettieri Jr, R.A.1    Hall, I.P.2    Maki, C.S.3    Murray, R.K.4
  • 93
    • 0028784682 scopus 로고
    • Stimulation by endothelin-1 of mitogen-activated protein kinases and DNA synthesis in bovine tracheal smooth muscle cells
    • Malarkey K, Chilvers ER, Lawson MF, Plevin R. 1995. Stimulation by endothelin-1 of mitogen-activated protein kinases and DNA synthesis in bovine tracheal smooth muscle cells. Br. J. Pharmacol. 116:2267-73
    • (1995) Br. J. Pharmacol , vol.116 , pp. 2267-2273
    • Malarkey, K.1    Chilvers, E.R.2    Lawson, M.F.3    Plevin, R.4
  • 94
    • 0029913468 scopus 로고    scopus 로고
    • The seven-transmembrane- spanning receptors for endothelin and thrombin cause proliferation of airway smooth muscle cells and activation of the extracellular regulated kinase and c-Jun NH2-terminal kinase groups of mitogen-activated protein kinases
    • Shapiro PS, Evans JN, Davis RJ, Posada JA. 1996. The seven-transmembrane- spanning receptors for endothelin and thrombin cause proliferation of airway smooth muscle cells and activation of the extracellular regulated kinase and c-Jun NH2-terminal kinase groups of mitogen-activated protein kinases. J. Biol. Chem. 271:5750-54
    • (1996) J. Biol. Chem , vol.271 , pp. 5750-5754
    • Shapiro, P.S.1    Evans, J.N.2    Davis, R.J.3    Posada, J.A.4
  • 95
    • 0031135506 scopus 로고    scopus 로고
    • Inhibition of ERKactivation attenuates endothelin-stimulated airway smooth muscle cell proliferation
    • Whelchel A, Evans J, Posada J. 1997. Inhibition of ERKactivation attenuates endothelin-stimulated airway smooth muscle cell proliferation. Am. J. Respir. Cell Mol. Biol. 16:589-96
    • (1997) Am. J. Respir. Cell Mol. Biol , vol.16 , pp. 589-596
    • Whelchel, A.1    Evans, J.2    Posada, J.3
  • 96
    • 0032407674 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: Role in mediating airway smooth muscle proliferation
    • Walker TR, Moore SM, Lawson MF, Panettieri RAJ, Chilvers ER. 1998. Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: role in mediating airway smooth muscle proliferation. Mol. Pharmacol. 54:1007-15
    • (1998) Mol. Pharmacol , vol.54 , pp. 1007-1015
    • Walker, T.R.1    Moore, S.M.2    Lawson, M.F.3    Panettieri, R.A.J.4    Chilvers, E.R.5
  • 97
    • 0032608413 scopus 로고    scopus 로고
    • Endothelin-stimulated ERK activation in airway smooth-muscle cells requires calcium influx and Raf activation
    • Vichi P, Whelchel A, Knot H, Nelson M, Kolch W, Posada J. 1999. Endothelin-stimulated ERK activation in airway smooth-muscle cells requires calcium influx and Raf activation. Am. J. Respir. Cell Mol. Biol. 20:99-105
    • (1999) Am. J. Respir. Cell Mol. Biol , vol.20 , pp. 99-105
    • Vichi, P.1    Whelchel, A.2    Knot, H.3    Nelson, M.4    Kolch, W.5    Posada, J.6
  • 99
    • 0031808337 scopus 로고    scopus 로고
    • Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway
    • Amishima M, Munakata M, Nasuhara Y, Sato A, Takahashi T, et al. 1998. Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway. Am. J. Respir. Crit. Care Med. 157:1907-12
    • (1998) Am. J. Respir. Crit. Care Med , vol.157 , pp. 1907-1912
    • Amishima, M.1    Munakata, M.2    Nasuhara, Y.3    Sato, A.4    Takahashi, T.5
  • 100
    • 0029611706 scopus 로고
    • Eosinophils as a potential source of platelet-derived growth factor B-chain (PDGF-B) in nasal polyposis and bronchial asthma
    • Ohno I, Nitta Y, Yamauchi K, Hoshi H, Honma M, et al. 1995. Eosinophils as a potential source of platelet-derived growth factor B-chain (PDGF-B) in nasal polyposis and bronchial asthma. Am. J. Respir. Cell Mol. Biol. 13:639-47
    • (1995) Am. J. Respir. Cell Mol. Biol , vol.13 , pp. 639-647
    • Ohno, I.1    Nitta, Y.2    Yamauchi, K.3    Hoshi, H.4    Honma, M.5
  • 101
    • 0028812421 scopus 로고
    • VIP inhibits basal and histamine-stimulated proliferation of human airway smooth muscle cells
    • Maruno K, Absood A, Said SI. 1995. VIP inhibits basal and histamine-stimulated proliferation of human airway smooth muscle cells. Am. J. Physiol. 268:L1047-51
    • (1995) Am. J. Physiol , vol.268
    • Maruno, K.1    Absood, A.2    Said, S.I.3
  • 102
    • 0030956451 scopus 로고    scopus 로고
    • MEK1 is required for PDGF-induced ERK activation and DNA synthesis in tracheal myocytes
    • Karpova AY, Abe MK, Li J, Liu P, Rhee JM, et al. 1997. MEK1 is required for PDGF-induced ERK activation and DNA synthesis in tracheal myocytes. Am. J. Physiol. 272:L558-65
    • (1997) Am. J. Physiol , vol.272
    • Karpova, A.Y.1    Abe, M.K.2    Li, J.3    Liu, P.4    Rhee, J.M.5
  • 103
    • 0033158915 scopus 로고    scopus 로고
    • β-hexosaminidase-induced activation of p44/42 mitogen-activated protein kinase is dependent on p21Ras and protein kinase C and mediates bovine airway smooth-muscle proliferation
    • Lew DB, Dempsey BK, Zhao Y, Muthalif M, Fatima S, Malik KU. 1999. β-hexosaminidase-induced activation of p44/42 mitogen-activated protein kinase is dependent on p21Ras and protein kinase C and mediates bovine airway smooth-muscle proliferation. Am. J. Respir. Cell Mol. Biol. 21:111-18
    • (1999) Am. J. Respir. Cell Mol. Biol , vol.21 , pp. 111-118
    • Lew, D.B.1    Dempsey, B.K.2    Zhao, Y.3    Muthalif, M.4    Fatima, S.5    Malik, K.U.6
  • 105
    • 0028985079 scopus 로고
    • MAP kinase pathways in yeast: For mating and more
    • Herskowitz I. 1995. MAP kinase pathways in yeast: for mating and more. Cell 80:187-97
    • (1995) Cell , vol.80 , pp. 187-197
    • Herskowitz, I.1
  • 106
    • 0029935418 scopus 로고    scopus 로고
    • Regulation of transcription by MAP kinase cascades
    • Treisman R. 1996. Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol. 8:205-15
    • (1996) Curr. Opin. Cell Biol , vol.8 , pp. 205-215
    • Treisman, R.1
  • 107
    • 0028823892 scopus 로고
    • Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast
    • Waskiewicz AJ, Cooper JA. 1995. Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast. Curr. Opin. Cell. Biol. 7:798-805
    • (1995) Curr. Opin. Cell. Biol , vol.7 , pp. 798-805
    • Waskiewicz, A.J.1    Cooper, J.A.2
  • 108
    • 0030911424 scopus 로고    scopus 로고
    • p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small Gtpase and is a ligand for profilin
    • Watanabe N, Madaule P, Reid T, Ishizaki T, Watanabe G, et al. 1997. p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small Gtpase and is a ligand for profilin. EMBO J. 16:3044-56
    • (1997) EMBO J , vol.16 , pp. 3044-3056
    • Watanabe, N.1    Madaule, P.2    Reid, T.3    Ishizaki, T.4    Watanabe, G.5
  • 110
    • 0029837986 scopus 로고    scopus 로고
    • Developmental control of cell cycle regulators: A fly's perspective
    • Edgar BA, Lehner CF. 1996. Developmental control of cell cycle regulators: a fly's perspective. Science 274:1646-52
    • (1996) Science , vol.274 , pp. 1646-1652
    • Edgar, B.A.1    Lehner, C.F.2
  • 111
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: Preventing an identity crisis
    • Elledge SJ. 1996. Cell cycle checkpoints: preventing an identity crisis. Science 274:1664-72
    • (1996) Science , vol.274 , pp. 1664-1672
    • Elledge, S.J.1
  • 113
    • 0028308224 scopus 로고
    • Identification of 2 serine residues of MEK-1 that are differentially phosphorylated during activation by raf and MEK kinase
    • Yan M, Templeton DJ. 1994. Identification of 2 serine residues of MEK-1 that are differentially phosphorylated during activation by raf and MEK kinase. J. Biol. Chem. 269:19067-73
    • (1994) J. Biol. Chem , vol.269 , pp. 19067-19073
    • Yan, M.1    Templeton, D.J.2
  • 114
    • 0033257938 scopus 로고    scopus 로고
    • Activation of K-p21ras and N-p21ras, but not H-p21ras, is necessary for mitogen-induced airway smooth muscle proliferation
    • Ammit AJ, Kane SA, Panettieri RAJ. 1999. Activation of K-p21ras and N-p21ras, but not H-p21ras, is necessary for mitogen-induced airway smooth muscle proliferation. Am. J. Respir. Cell. Mol. Biol. 21:719-27
    • (1999) Am. J. Respir. Cell. Mol. Biol , vol.21 , pp. 719-727
    • Ammit, A.J.1    Kane, S.A.2    Panettieri, R.A.J.3
  • 115
    • 0033145531 scopus 로고    scopus 로고
    • Platelet-derived growth factor stimulation of mitogen-activated protein kinases and cyclin D1 promoter activity in cultured airway smooth-muscle cells. Role of Ras
    • Page K, Li J, Hershenson MB. 1999. Platelet-derived growth factor stimulation of mitogen-activated protein kinases and cyclin D1 promoter activity in cultured airway smooth-muscle cells. Role of Ras. Am. J. Respir. Cell Mol. Biol. 20:1294-302
    • (1999) Am. J. Respir. Cell Mol. Biol , vol.20 , pp. 1294-1302
    • Page, K.1    Li, J.2    Hershenson, M.B.3
  • 116
    • 0031135506 scopus 로고    scopus 로고
    • Inhibition of ERK activation attenuates endothelin-stimulated airway smooth muscle prolifeation
    • Whelchel A, Evans J, Posada J. 1997. Inhibition of ERK activation attenuates endothelin-stimulated airway smooth muscle prolifeation. Am. J. Respir. Cell Mol. Biol. 16:589-96
    • (1997) Am. J. Respir. Cell Mol. Biol , vol.16 , pp. 589-596
    • Whelchel, A.1    Evans, J.2    Posada, J.3
  • 117
    • 0028970609 scopus 로고
    • Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
    • Albanese C, Johnson J, Watanabe G, Eklund N, Vu D, et al. 1995. Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions. J. Biol. Chem. 270:23589-97
    • (1995) J. Biol. Chem , vol.270 , pp. 23589-23597
    • Albanese, C.1    Johnson, J.2    Watanabe, G.3    Eklund, N.4    Vu, D.5
  • 119
    • 0032088751 scopus 로고    scopus 로고
    • Catalytic activation of extracellular signal-regulated kinases induces cyclin D1 expression in airway smooth muscle
    • Ramakrishnan M, Musa NL, Li J, Liu P, Pestell RG, Hershenson MB. 1998. Catalytic activation of extracellular signal-regulated kinases induces cyclin D1 expression in airway smooth muscle. Am. J. Respir. Cell Mol. Biol. 18:736-40
    • (1998) Am. J. Respir. Cell Mol. Biol , vol.18 , pp. 736-740
    • Ramakrishnan, M.1    Musa, N.L.2    Li, J.3    Liu, P.4    Pestell, R.G.5    Hershenson, M.B.6
  • 121
    • 0032477854 scopus 로고    scopus 로고
    • Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
    • Cheng M, Sexl V, Sherr CJ, Roussel MF. 1998. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). Proc. Natl. Acad. Sci. USA 95:1091-96
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1091-1096
    • Cheng, M.1    Sexl, V.2    Sherr, C.J.3    Roussel, M.F.4
  • 122
    • 0031453368 scopus 로고    scopus 로고
    • Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27
    • Weber JD, Hu W, Jefcoat SC Jr, Raben DM, Baldassare JJ. 1997. Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27. J. Biol. Chem. 272:32966-71
    • (1997) J. Biol. Chem , vol.272 , pp. 32966-32971
    • Weber, J.D.1    Hu, W.2    Jefcoat Jr, S.C.3    Raben, D.M.4    Baldassare, J.J.5
  • 123
    • 0027293137 scopus 로고
    • Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts
    • Quelle DE, Ashmun RA, Shurtleff SA, Kato JY, Bar-Sagi D, et al. 1993. Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. GenesDev. 7:1559-71
    • (1993) GenesDev , vol.7 , pp. 1559-1571
    • Quelle, D.E.1    Ashmun, R.A.2    Shurtleff, S.A.3    Kato, J.Y.4    Bar-Sagi, D.5
  • 124
    • 0028173667 scopus 로고
    • Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system
    • Resnitzky D, Gossen M, Bujard H, Reed SI. 1994. Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol. Cell. Biol. 14:1669-79
    • (1994) Mol. Cell. Biol , vol.14 , pp. 1669-1679
    • Resnitzky, D.1    Gossen, M.2    Bujard, H.3    Reed, S.I.4
  • 125
    • 0042734621 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase signalling - which way to target?
    • Wymann MP, Zvelebil M, Laffargue M. 2003. Phosphoinositide 3-kinase signalling - which way to target? Trends Pharmacol. Sci. 24:366-76
    • (2003) Trends Pharmacol. Sci , vol.24 , pp. 366-376
    • Wymann, M.P.1    Zvelebil, M.2    Laffargue, M.3
  • 128
    • 0033791846 scopus 로고    scopus 로고
    • Regulation of cyclin D1 expression and DNA synthesis by phosphatidylinositol 3-kinase in airway smooth muscle cells
    • Page K, Li J, Wang Y, Kardia S, Pestell RG, Hershenson MB. 2000. Regulation of cyclin D1 expression and DNA synthesis by phosphatidylinositol 3-kinase in airway smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 23:436-43
    • (2000) Am. J. Respir. Cell Mol. Biol , vol.23 , pp. 436-443
    • Page, K.1    Li, J.2    Wang, Y.3    Kardia, S.4    Pestell, R.G.5    Hershenson, M.B.6
  • 129
    • 0029785079 scopus 로고    scopus 로고
    • A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells
    • Scott PH, Belham CM, al-Hafidh J, Chilvers ER, Peacock AJ, et al. 1996. A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells. Biochem. J. 318:965-71
    • (1996) Biochem. J , vol.318 , pp. 965-971
    • Scott, P.H.1    Belham, C.M.2    al-Hafidh, J.3    Chilvers, E.R.4    Peacock, A.J.5
  • 131
    • 0029278739 scopus 로고
    • PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase
    • Hawkins PT, Eguinoa A, Qiu R-G, Stokoe D, Cooke FT, et al. 1995. PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase. Curr. Biol. 5:393-403
    • (1995) Curr. Biol , vol.5 , pp. 393-403
    • Hawkins, P.T.1    Eguinoa, A.2    Qiu, R.-G.3    Stokoe, D.4    Cooke, F.T.5
  • 132
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskelton
    • Hall A. 1998. Rho GTPases and the actin cytoskelton. Science 279:509-14
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 133
    • 0028429961 scopus 로고
    • Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling
    • Wennstrom S, Hawkins P, Cooke F, Hara K, Yonesawa K, et al. 1994. Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr. Biol. 4:385-93
    • (1994) Curr. Biol , vol.4 , pp. 385-393
    • Wennstrom, S.1    Hawkins, P.2    Cooke, F.3    Hara, K.4    Yonesawa, K.5
  • 134
    • 0030293886 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways
    • Reif K, Nobes CD, Thomas G, Hall A, Cantrell DA. 1996. Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways. Curr. Biol. 6:1445-55
    • (1996) Curr. Biol , vol.6 , pp. 1445-1455
    • Reif, K.1    Nobes, C.D.2    Thomas, G.3    Hall, A.4    Cantrell, D.A.5
  • 135
    • 0033618344 scopus 로고    scopus 로고
    • Characterization of a Rac1 signaling pathway to cyclin D1 expression in airway smooth muscle cells
    • Page K, Li J, Hodge JA, Liu PT, Vanden Hoek TL, et al. 1999. Characterization of a Rac1 signaling pathway to cyclin D1 expression in airway smooth muscle cells. J. Biol. Chem. 274:22065-71
    • (1999) J. Biol. Chem , vol.274 , pp. 22065-22071
    • Page, K.1    Li, J.2    Hodge, J.A.3    Liu, P.T.4    Vanden Hoek, T.L.5
  • 137
    • 0025944684 scopus 로고
    • Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1
    • Abo A, Pick E, Hall A, Totty N, Teahan CG, Segal AW. 1991. Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1. Nature 353:668-70
    • (1991) Nature , vol.353 , pp. 668-670
    • Abo, A.1    Pick, E.2    Hall, A.3    Totty, N.4    Teahan, C.G.5    Segal, A.W.6
  • 138
    • 0026795613 scopus 로고
    • Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: P67-phox, p47-phox, p21rac1, and cytochrome b-245
    • Abo A, Boyhan A, West I, Thrasher AJ, Segal AW. 1992. Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: p67-phox, p47-phox, p21rac1, and cytochrome b-245. J. Biol. Chem. 267:16767-70
    • (1992) J. Biol. Chem , vol.267 , pp. 16767-16770
    • Abo, A.1    Boyhan, A.2    West, I.3    Thrasher, A.J.4    Segal, A.W.5
  • 139
    • 0033538449 scopus 로고    scopus 로고
    • Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle
    • Brar SS, Kennedy TP, Whorton AR, Murphy TM, Chitano P, Hoidal JR. 1999. Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle. J. Biol. Chem. 274:20017-26
    • (1999) J. Biol. Chem , vol.274 , pp. 20017-20026
    • Brar, S.S.1    Kennedy, T.P.2    Whorton, A.R.3    Murphy, T.M.4    Chitano, P.5    Hoidal, J.R.6
  • 142
    • 0033161645 scopus 로고    scopus 로고
    • Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle
    • Fernandes D, Guida E, Koutsoubos V, Harris T, Vadiveloo P, et al. 1999. Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle. Am. J. Respir. Cell Mol. Biol. 21:77-88
    • (1999) Am. J. Respir. Cell Mol. Biol , vol.21 , pp. 77-88
    • Fernandes, D.1    Guida, E.2    Koutsoubos, V.3    Harris, T.4    Vadiveloo, P.5
  • 144
    • 3442876677 scopus 로고    scopus 로고
    • Dysfunctional interaction of C/EBPα and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells
    • Roth M, Johnson PR, Borger P, Bihl MP, Rudiger JJ, et al. 2004. Dysfunctional interaction of C/EBPα and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells. N. Engl. J. Med. 351:560-74
    • (2004) N. Engl. J. Med , vol.351 , pp. 560-574
    • Roth, M.1    Johnson, P.R.2    Borger, P.3    Bihl, M.P.4    Rudiger, J.J.5
  • 145
    • 11144358047 scopus 로고    scopus 로고
    • Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression
    • Woodruff PG, Dolganov GM, Ferrando RE, Donnelly S, Hays SR, et al. 2004. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am. J. Respir. Crit. Care Med. 169:1001-6
    • (2004) Am. J. Respir. Crit. Care Med , vol.169 , pp. 1001-1006
    • Woodruff, P.G.1    Dolganov, G.M.2    Ferrando, R.E.3    Donnelly, S.4    Hays, S.R.5
  • 146
    • 0023772662 scopus 로고
    • Cell cycle versus density dependence of smooth muscle α actin expression in cultured rat aortic smooth muscle cells
    • Blank RS, Thompson MM, Owens GK. 1988. Cell cycle versus density dependence of smooth muscle α actin expression in cultured rat aortic smooth muscle cells. J. Cell Biol. 107:299-306
    • (1988) J. Cell Biol , vol.107 , pp. 299-306
    • Blank, R.S.1    Thompson, M.M.2    Owens, G.K.3
  • 150
    • 0141925661 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB-mediated activation of akt suppresses smooth muscle-specific gene expression through inhibition of mitogen-activated protein kinase and redistribution of serum response factor
    • Kaplan-Albuquerque N, Garat C, Desseva C, Jones PL, Nemenoff RA. 2003. Platelet-derived growth factor-BB-mediated activation of akt suppresses smooth muscle-specific gene expression through inhibition of mitogen-activated protein kinase and redistribution of serum response factor. J. Biol. Chem. 278:39830-38
    • (2003) J. Biol. Chem , vol.278 , pp. 39830-39838
    • Kaplan-Albuquerque, N.1    Garat, C.2    Desseva, C.3    Jones, P.L.4    Nemenoff, R.A.5
  • 151
    • 4444302962 scopus 로고    scopus 로고
    • Phophatidylinositol-3 kinase/mammalian target of rapamycin/p70S6K regulates contractile protein accumulation in airway myocyte differentiation
    • Halayko AJ, Kardia S, Stelmack GL, McConville J, Tam J, et al. 2004. Phophatidylinositol-3 kinase/mammalian target of rapamycin/p70S6K regulates contractile protein accumulation in airway myocyte differentiation. Am. J. Respir. Cell Mol. Biol. 31:266-75
    • (2004) Am. J. Respir. Cell Mol. Biol , vol.31 , pp. 266-275
    • Halayko, A.J.1    Kardia, S.2    Stelmack, G.L.3    McConville, J.4    Tam, J.5
  • 152
    • 0032891634 scopus 로고    scopus 로고
    • Divergent differentiation paths in airway smooth muscle culture: Induction of functionally contractile myocytes
    • Halayko AJ, Camoretti-Mercado B, Forsythe SM, Vieira JE, Mitchell RW, et al. 1999. Divergent differentiation paths in airway smooth muscle culture: induction of functionally contractile myocytes. Am. J. Physiol. 276:L197-206
    • (1999) Am. J. Physiol , vol.276
    • Halayko, A.J.1    Camoretti-Mercado, B.2    Forsythe, S.M.3    Vieira, J.E.4    Mitchell, R.W.5
  • 153
    • 0034730524 scopus 로고    scopus 로고
    • Physiological control of smooth muscle-specific gene expression through regulated nuclear translocation of serum response factor
    • Camoretti-Mercado B, Liu H, Halayko A, Forsythe S, Kyle J, et al. 2000. Physiological control of smooth muscle-specific gene expression through regulated nuclear translocation of serum response factor. J. Biol. Chem. 275:30387-93
    • (2000) J. Biol. Chem , vol.275 , pp. 30387-30393
    • Camoretti-Mercado, B.1    Liu, H.2    Halayko, A.3    Forsythe, S.4    Kyle, J.5
  • 154
    • 12144285756 scopus 로고    scopus 로고
    • Human bronchial smooth muscle cell lines show a hypertrophic phenotype typical of severe asthma
    • Zhou L, Li J, Goldsmith AM, Newcomb DC, Giannola DM, et al. 2004. Human bronchial smooth muscle cell lines show a hypertrophic phenotype typical of severe asthma. Am. J. Respir. Crit. Care Med. 169:703-11
    • (2004) Am. J. Respir. Crit. Care Med , vol.169 , pp. 703-711
    • Zhou, L.1    Li, J.2    Goldsmith, A.M.3    Newcomb, D.C.4    Giannola, D.M.5
  • 155
    • 0037097863 scopus 로고    scopus 로고
    • Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
    • Fingar DC, Salama S, Tsou C, Harlow E, Blenis J. 2002. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev. 16:1472-87
    • (2002) Genes Dev , vol.16 , pp. 1472-1487
    • Fingar, D.C.1    Salama, S.2    Tsou, C.3    Harlow, E.4    Blenis, J.5
  • 156
    • 0029094994 scopus 로고
    • Contraction accelerates myosin heavy chain synthesis rates in adult cardiocytes by an increase in the rate of translational initiation
    • Ivester CT, Tuxworth WJ, Cooper GIV, McDermott PJ. 1995. Contraction accelerates myosin heavy chain synthesis rates in adult cardiocytes by an increase in the rate of translational initiation. J. Biol. Chem. 270:21950-57
    • (1995) J. Biol. Chem , vol.270 , pp. 21950-21957
    • Ivester, C.T.1    Tuxworth, W.J.2    Cooper, G.I.V.3    McDermott, P.J.4
  • 157
    • 0033000348 scopus 로고    scopus 로고
    • Mechanical activity in heart regulates translation of α-myosin heavy chain mRNA but not its localization
    • Nikcevic G, Heidkamp MC, Perhonen M, Russell B. 1999. Mechanical activity in heart regulates translation of α-myosin heavy chain mRNA but not its localization. Am. J. Physiol. Heart Circ. Physiol. 276:H2013-19
    • (1999) Am. J. Physiol. Heart Circ. Physiol , vol.276
    • Nikcevic, G.1    Heidkamp, M.C.2    Perhonen, M.3    Russell, B.4
  • 159
    • 4043140199 scopus 로고    scopus 로고
    • Molecular and cellular determinants of skeletal muscle atrophy and hypertrophy
    • Sartorelli V, Fulco M. 2004. Molecular and cellular determinants of skeletal muscle atrophy and hypertrophy. Sci. STKE 244:re11
    • (2004) Sci. STKE , vol.244
    • Sartorelli, V.1    Fulco, M.2
  • 160
    • 0041424822 scopus 로고    scopus 로고
    • Molecular mechanisms modulating muscle mass
    • Glass DJ. 2003. Molecular mechanisms modulating muscle mass. Trends Mol. Med. 9:344-50
    • (2003) Trends Mol. Med , vol.9 , pp. 344-350
    • Glass, D.J.1
  • 161
  • 162
    • 0032908064 scopus 로고    scopus 로고
    • Stimulation of myofibrillar synthesis by exercise is mediated by more efficient translation of mRNA
    • Welle S, Bhatt K, Thornton CA. 1999. Stimulation of myofibrillar synthesis by exercise is mediated by more efficient translation of mRNA. J. Appl. Physiol. 86:1220-25
    • (1999) J. Appl. Physiol , vol.86 , pp. 1220-1225
    • Welle, S.1    Bhatt, K.2    Thornton, C.A.3
  • 163
    • 0023916169 scopus 로고
    • Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells
    • Geisterfer A, Peach M, Owens G. 1988. Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells. Circ. Res. 62:749-56
    • (1988) Circ. Res , vol.62 , pp. 749-756
    • Geisterfer, A.1    Peach, M.2    Owens, G.3
  • 165
    • 33746004253 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor β-enhanced serum response factor-dependent transcription by SMAD7
    • Camoretti-Mercado B, Fernandes DJ, Dewundara S, Churchill J, Ma L, et al. 2006. Inhibition of transforming growth factor β-enhanced serum response factor-dependent transcription by SMAD7. J. Biol. Chem. 281:20383-92
    • (2006) J. Biol. Chem , vol.281 , pp. 20383-20392
    • Camoretti-Mercado, B.1    Fernandes, D.J.2    Dewundara, S.3    Churchill, J.4    Ma, L.5
  • 166
    • 0030066934 scopus 로고    scopus 로고
    • Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation
    • Beretta L, Gingras AC, Svitkin YV, Hall MN, Sonenberg N. 1996. Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. EMBO J. 15:658-64
    • (1996) EMBO J , vol.15 , pp. 658-664
    • Beretta, L.1    Gingras, A.C.2    Svitkin, Y.V.3    Hall, M.N.4    Sonenberg, N.5
  • 167
    • 0030881836 scopus 로고    scopus 로고
    • Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin
    • Brunn GJ, Hudson CC, Sekuli A, Williams JM, Hosoi H, et al. 1997. Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. Science 277:99-101
    • (1997) Science , vol.277 , pp. 99-101
    • Brunn, G.J.1    Hudson, C.C.2    Sekuli, A.3    Williams, J.M.4    Hosoi, H.5
  • 168
    • 0030977269 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
    • Waskiewicz AJ, Flynn A, Proud CG, Cooper JA. 1997. Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. EMBO J. 16:1909-20
    • (1997) EMBO J , vol.16 , pp. 1909-1920
    • Waskiewicz, A.J.1    Flynn, A.2    Proud, C.G.3    Cooper, J.A.4
  • 169
    • 0035133659 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells
    • Scheper GC, Morrice NA, Kleijn M, Proud CG. 2001. The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells. Mol. Cell. Biol. 21:743-54
    • (2001) Mol. Cell. Biol , vol.21 , pp. 743-754
    • Scheper, G.C.1    Morrice, N.A.2    Kleijn, M.3    Proud, C.G.4
  • 170
    • 0032054816 scopus 로고    scopus 로고
    • The mRNA 5′ cap-binding protein eIF4E and control of cell growth
    • Sonenberg N, Gingras AC. 1998. The mRNA 5′ cap-binding protein eIF4E and control of cell growth. Curr. Opin. Cell Biol. 10:268-75
    • (1998) Curr. Opin. Cell Biol , vol.10 , pp. 268-275
    • Sonenberg, N.1    Gingras, A.C.2
  • 171
    • 0035032444 scopus 로고    scopus 로고
    • The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5′ secondary structure
    • Svitkin YV, Pause A, Haghighat A, Pyronnet S, Witherell G, et al. 2001. The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5′ secondary structure. RNA 7:382-94
    • (2001) RNA , vol.7 , pp. 382-394
    • Svitkin, Y.V.1    Pause, A.2    Haghighat, A.3    Pyronnet, S.4    Witherell, G.5
  • 172
    • 0032498112 scopus 로고    scopus 로고
    • Regulation of eukaryotic initiation factor eIF2B: Glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin
    • Welsh GI, Miller CM, Loughlin AJ, Price NT, Proud CG. 1998. Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin. FEBS Lett. 421:125-30
    • (1998) FEBS Lett , vol.421 , pp. 125-130
    • Welsh, G.I.1    Miller, C.M.2    Loughlin, A.J.3    Price, N.T.4    Proud, C.G.5
  • 174
    • 0033258521 scopus 로고    scopus 로고
    • Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB
    • Verdu J, Buratovich MA, Wilder EL, Birnbaum MJ. 1999. Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB. Nat. Cell Biol. 1:500-6
    • (1999) Nat. Cell Biol , vol.1 , pp. 500-506
    • Verdu, J.1    Buratovich, M.A.2    Wilder, E.L.3    Birnbaum, M.J.4
  • 175
    • 0034312315 scopus 로고    scopus 로고
    • Regulation of cellular growth by the Drosophila target of rapamycin dTOR
    • Zhang H, Stallock JP, Ng JC, Reinhard C, Neufeld TP. 2000. Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev. 14:2712-24
    • (2000) Genes Dev , vol.14 , pp. 2712-2724
    • Zhang, H.1    Stallock, J.P.2    Ng, J.C.3    Reinhard, C.4    Neufeld, T.P.5
  • 177
    • 0032578999 scopus 로고    scopus 로고
    • Protein Kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
    • Stephens L, Anderson K, Stokoe D, Erdjument-Bromage H, Painter GF, et al. 1998. Protein Kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science 279:710-14
    • (1998) Science , vol.279 , pp. 710-714
    • Stephens, L.1    Anderson, K.2    Stokoe, D.3    Erdjument-Bromage, H.4    Painter, G.F.5
  • 179
    • 0034644523 scopus 로고    scopus 로고
    • Cellular signaling: Pivoting around PDK-1
    • Toker A, Newton AC. 2000. Cellular signaling: pivoting around PDK-1. Cell 103:185-88
    • (2000) Cell , vol.103 , pp. 185-188
    • Toker, A.1    Newton, A.C.2
  • 180
    • 0034653608 scopus 로고    scopus 로고
    • The PI3K-PDK1 connection: More than just a road to PKB
    • Vanhaesebroeck B, Alessi DR. 2000. The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 346:561-76
    • (2000) Biochem. J , vol.346 , pp. 561-576
    • Vanhaesebroeck, B.1    Alessi, D.R.2
  • 181
    • 2642548034 scopus 로고    scopus 로고
    • eIF4E binding protein 1 and H-Ras are novel substrates for the protein kinase activity of class-I phosphoinositide 3-kinase
    • Foukas LC, Shepherd PR. 2004. eIF4E binding protein 1 and H-Ras are novel substrates for the protein kinase activity of class-I phosphoinositide 3-kinase. Biochem. Biophys. Res. Commun. 319:541-49
    • (2004) Biochem. Biophys. Res. Commun , vol.319 , pp. 541-549
    • Foukas, L.C.1    Shepherd, P.R.2
  • 182
    • 0037192868 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites
    • Herbert TP, Tee AR, Proud CG. 2002. The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites. J. Biol. Chem. 277:11591-96
    • (2002) J. Biol. Chem , vol.277 , pp. 11591-11596
    • Herbert, T.P.1    Tee, A.R.2    Proud, C.G.3
  • 183
    • 0034982971 scopus 로고    scopus 로고
    • TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
    • Gao X, Pan D. 2001. TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. Genes Dev. 15:1383-92
    • (2001) Genes Dev , vol.15 , pp. 1383-1392
    • Gao, X.1    Pan, D.2
  • 184
    • 0035805162 scopus 로고    scopus 로고
    • Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
    • Potter CJ, Huang H, Xu T. 2001. Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell 105:357-68
    • (2001) Cell , vol.105 , pp. 357-368
    • Potter, C.J.1    Huang, H.2    Xu, T.3
  • 185
    • 0035805180 scopus 로고    scopus 로고
    • The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation
    • Tapon N, Ito N, Dickson BJ, Treisman JE, Hariharan IK. 2001. The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell 105:345-55
    • (2001) Cell , vol.105 , pp. 345-355
    • Tapon, N.1    Ito, N.2    Dickson, B.J.3    Treisman, J.E.4    Hariharan, I.K.5
  • 186
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • Inoki K, Li Y, Zhu T, Wu J, Guan KL. 2002. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 4:648-57
    • (2002) Nat. Cell Biol , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.L.5
  • 187
    • 0036712905 scopus 로고    scopus 로고
    • Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
    • Gao X, Zhang Y, Arrazola P, Hino O, Kobayashi T, et al. 2002. Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling. Nat. Cell Biol. 4:699-704
    • (2002) Nat. Cell Biol , vol.4 , pp. 699-704
    • Gao, X.1    Zhang, Y.2    Arrazola, P.3    Hino, O.4    Kobayashi, T.5
  • 188
    • 0036342294 scopus 로고    scopus 로고
    • Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
    • Manning BD, Tee AR, Logsdon MN, Blenis J, Cantley LC. 2002. Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol. Cell. Biol. 10:151-62
    • (2002) Mol. Cell. Biol , vol.10 , pp. 151-162
    • Manning, B.D.1    Tee, A.R.2    Logsdon, M.N.3    Blenis, J.4    Cantley, L.C.5
  • 189
    • 0037108750 scopus 로고    scopus 로고
    • Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
    • Tee AR, Fingar DC, Manning BD, Kwiatkowski DJ, Cantley LC, Blenis J. 2002. Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. Proc. Natl. Acad. Sci. USA 99:13571-76
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13571-13576
    • Tee, A.R.1    Fingar, D.C.2    Manning, B.D.3    Kwiatkowski, D.J.4    Cantley, L.C.5    Blenis, J.6
  • 190
    • 0037163033 scopus 로고    scopus 로고
    • Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)
    • Goncharova EA, Goncharov DA, Eszterhas A, Hunter DS, Glassberg MK, et al. 2002. Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM). J. Biol. Chem. 277:30958-67
    • (2002) J. Biol. Chem , vol.277 , pp. 30958-30967
    • Goncharova, E.A.1    Goncharov, D.A.2    Eszterhas, A.3    Hunter, D.S.4    Glassberg, M.K.5
  • 191
    • 0042701991 scopus 로고    scopus 로고
    • Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
    • Tee AR, Manning BD, Roux PP, Cantley LC, Blenis J. 2003. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. Curr. Biol. 13:1259-68
    • (2003) Curr. Biol , vol.13 , pp. 1259-1268
    • Tee, A.R.1    Manning, B.D.2    Roux, P.P.3    Cantley, L.C.4    Blenis, J.5
  • 192
    • 0043127125 scopus 로고    scopus 로고
    • Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
    • Inoki K, Li Y, Xu T, Guan KL. 2002. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev. 17:1829-34
    • (2002) Genes Dev , vol.17 , pp. 1829-1834
    • Inoki, K.1    Li, Y.2    Xu, T.3    Guan, K.L.4
  • 193
    • 0034051278 scopus 로고    scopus 로고
    • Loss of Rhb1, a Rheb-Related GTPase in fission yeast, causes growth arrest with a terminal phenotype similar to that caused by nitrogen starvation
    • Mach KE, Furge KA, Albright CF. 2000. Loss of Rhb1, a Rheb-Related GTPase in fission yeast, causes growth arrest with a terminal phenotype similar to that caused by nitrogen starvation. Genetics 155:611-22
    • (2000) Genetics , vol.155 , pp. 611-622
    • Mach, K.E.1    Furge, K.A.2    Albright, C.F.3
  • 194
    • 7944235758 scopus 로고    scopus 로고
    • Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
    • Jacinto E, Loewith R, Schmidt A, Lin S, Ruegg MA, et al. 2004. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat. Cell Biol. 6:1122-28
    • (2004) Nat. Cell Biol , vol.6 , pp. 1122-1128
    • Jacinto, E.1    Loewith, R.2    Schmidt, A.3    Lin, S.4    Ruegg, M.A.5
  • 195
    • 33749076673 scopus 로고    scopus 로고
    • SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
    • Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, et al. 2006. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127:125-37
    • (2006) Cell , vol.127 , pp. 125-137
    • Jacinto, E.1    Facchinetti, V.2    Liu, D.3    Soto, N.4    Wei, S.5
  • 196
    • 33751079895 scopus 로고    scopus 로고
    • Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity
    • Yang Q, Inoki K, Ikenoue T, Guan K-L. 2006. Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. Genes Dev. 20:2820-32
    • (2006) Genes Dev , vol.20 , pp. 2820-2832
    • Yang, Q.1    Inoki, K.2    Ikenoue, T.3    Guan, K.-L.4
  • 197
    • 33947330747 scopus 로고    scopus 로고
    • Re-evaluating AKT regulation: Role of TOR complex 2 in tissue growth
    • Hietakangas V, Cohen SM. 2007. Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth. Genes Dev. 21:632-37
    • (2007) Genes Dev , vol.21 , pp. 632-637
    • Hietakangas, V.1    Cohen, S.M.2
  • 198
    • 0034671768 scopus 로고    scopus 로고
    • Phosphorylation- dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
    • Alt JR, Cleveland JL, Hannink M, Diehl JA. 2000. Phosphorylation- dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes Dev. 14:3102-14
    • (2000) Genes Dev , vol.14 , pp. 3102-3114
    • Alt, J.R.1    Cleveland, J.L.2    Hannink, M.3    Diehl, J.A.4
  • 199
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization
    • Diehl JA, Cheng M, Roussel MF, Sherr CJ. 1998. Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization. Genes. Dev. 12:3499-5511
    • (1998) Genes. Dev , vol.12 , pp. 3499-5511
    • Diehl, J.A.1    Cheng, M.2    Roussel, M.F.3    Sherr, C.J.4
  • 200
    • 0037155824 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation
    • Rossig L, Badorff C, Holzmann Y, Zeiher AM, Dimmeier S. 2002. Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation. J. Biol. Chem. 277:9684-89
    • (2002) J. Biol. Chem , vol.277 , pp. 9684-9689
    • Rossig, L.1    Badorff, C.2    Holzmann, Y.3    Zeiher, A.M.4    Dimmeier, S.5
  • 201
    • 24344471377 scopus 로고    scopus 로고
    • 4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy
    • Zhou L, Goldsmith AM, Bentley JK, Jia Y, Rodriguez ML, et al. 2005. 4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy. Am. J. Respir. Cell Mol. Biol. 33:195-202
    • (2005) Am. J. Respir. Cell Mol. Biol , vol.33 , pp. 195-202
    • Zhou, L.1    Goldsmith, A.M.2    Bentley, J.K.3    Jia, Y.4    Rodriguez, M.L.5
  • 202
    • 0037173639 scopus 로고    scopus 로고
    • Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
    • Van Eerdewegh P, Little RD, Dupuis J, Del Mastro RG, Falls K, et al. 2002. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 418:426-30
    • (2002) Nature , vol.418 , pp. 426-430
    • Van Eerdewegh, P.1    Little, R.D.2    Dupuis, J.3    Del Mastro, R.G.4    Falls, K.5
  • 203
    • 0141887468 scopus 로고    scopus 로고
    • Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations
    • Howard TD, Postma DS, Jongepier H, Moore WC, Koppelman GH, et al. 2003. Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations. J. Allergy Clin. Immunol. 112:717-22
    • (2003) J. Allergy Clin. Immunol , vol.112 , pp. 717-722
    • Howard, T.D.1    Postma, D.S.2    Jongepier, H.3    Moore, W.C.4    Koppelman, G.H.5
  • 204
  • 206
    • 0242288092 scopus 로고    scopus 로고
    • Human ADAM33 messenger RNA expression profile and post-transcriptional regulation
    • Umland SP, Garlisi CG, Shah H, Wan Y, Zou J, et al. 2003. Human ADAM33 messenger RNA expression profile and post-transcriptional regulation. Am. J. Respir. Cell Mol. Biol. 29:571-82
    • (2003) Am. J. Respir. Cell Mol. Biol , vol.29 , pp. 571-582
    • Umland, S.P.1    Garlisi, C.G.2    Shah, H.3    Wan, Y.4    Zou, J.5
  • 209
    • 0025342014 scopus 로고
    • Abnormalities in airway smooth muscle in fatal asthma
    • Bai TR. 1990. Abnormalities in airway smooth muscle in fatal asthma. Am. Rev. Respir. Dis. 141:552-57
    • (1990) Am. Rev. Respir. Dis , vol.141 , pp. 552-557
    • Bai, T.R.1
  • 212
    • 0023640899 scopus 로고
    • In vivo versus in vitro human airway responsiveness to different pharmacologic stimuli
    • Thomson NC. 1987. In vivo versus in vitro human airway responsiveness to different pharmacologic stimuli. Am. Rev. Respir. Dis. 136:S58-62
    • (1987) Am. Rev. Respir. Dis , vol.136
    • Thomson, N.C.1
  • 216
    • 0028294123 scopus 로고
    • Exposure of immature rats to hyperoxia increases tracheal smooth muscle stress generation in vitro
    • Hershenson MB, Wylam ME, Punjabi N, Umans JG, Schumacker PT, et al. 1994. Exposure of immature rats to hyperoxia increases tracheal smooth muscle stress generation in vitro. J. Appl. Physiol. 76:743-49
    • (1994) J. Appl. Physiol , vol.76 , pp. 743-749
    • Hershenson, M.B.1    Wylam, M.E.2    Punjabi, N.3    Umans, J.G.4    Schumacker, P.T.5
  • 218
    • 0031034464 scopus 로고    scopus 로고
    • Autocrine role of interleukin 1β in altered responsiveness of atopic asthmatic sensitized airway smooth muscle
    • Hakonarson H, Herrick DJ, Serrano PG, Grunstein MM. 1997. Autocrine role of interleukin 1β in altered responsiveness of atopic asthmatic sensitized airway smooth muscle. J. Clin. Invest 99:117-24
    • (1997) J. Clin. Invest , vol.99 , pp. 117-124
    • Hakonarson, H.1    Herrick, D.J.2    Serrano, P.G.3    Grunstein, M.M.4
  • 219
    • 0034747215 scopus 로고    scopus 로고
    • Association between IL-1β/TNF-α-induced glucocorticoid- sensitive changes in multiple gene expression and altered responsiveness in airway smooth muscle
    • Hakonarson H, Halapi E, Whelan R, Gulcher J, Stefansson K, Grunstein MM. 2001. Association between IL-1β/TNF-α-induced glucocorticoid- sensitive changes in multiple gene expression and altered responsiveness in airway smooth muscle. Am. J. Respir. Cell Mol. Biol. 25:761-71
    • (2001) Am. J. Respir. Cell Mol. Biol , vol.25 , pp. 761-771
    • Hakonarson, H.1    Halapi, E.2    Whelan, R.3    Gulcher, J.4    Stefansson, K.5    Grunstein, M.M.6
  • 220
    • 3042795833 scopus 로고    scopus 로고
    • Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: Role of CD38/cyclic adenosine diphosphate ribose pathway
    • Deshpande DA, Dogan S, Walseth TF, Miller SM, Amrani Y, et al. 2004. Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway. Am. J. Respir. Cell Mol. Biol. 31:36-42
    • (2004) Am. J. Respir. Cell Mol. Biol , vol.31 , pp. 36-42
    • Deshpande, D.A.1    Dogan, S.2    Walseth, T.F.3    Miller, S.M.4    Amrani, Y.5
  • 223
    • 13444282306 scopus 로고    scopus 로고
    • 2+ sensitization of bronchial smooth muscle contraction in airway hyperresponsiveness
    • 2+ sensitization of bronchial smooth muscle contraction in airway hyperresponsiveness. J. Smooth Muscle Res. 40:155-67
    • (2004) J. Smooth Muscle Res , vol.40 , pp. 155-167
    • Chiba, Y.1    Misawa, M.2
  • 224
    • 0036280306 scopus 로고    scopus 로고
    • Suppression of airway hyperresponsiveness induced by ovalbumin sensitisation and RSV infection with Y-27632, a Rho kinase inhibitor
    • Hashimoto K, Peebles RS Jr, Sheller JR, Jarzecka K, FurlongJ, et al. 2002. Suppression of airway hyperresponsiveness induced by ovalbumin sensitisation and RSV infection with Y-27632, a Rho kinase inhibitor. Thorax 57:524-27
    • (2002) Thorax , vol.57 , pp. 524-527
    • Hashimoto, K.1    Peebles Jr, R.S.2    Sheller, J.R.3    Jarzecka, K.4    FurlongJ5
  • 225
    • 0034892133 scopus 로고    scopus 로고
    • Augmented acetylcholine-induced translocation of RhoA in bronchial smooth muscle from antigen-induced airway hyperresponsive rats
    • Chiba Y, Sakai H, Misawa M. 2001. Augmented acetylcholine-induced translocation of RhoA in bronchial smooth muscle from antigen-induced airway hyperresponsive rats. Br. J. Pharmacol. 133:886-90
    • (2001) Br. J. Pharmacol , vol.133 , pp. 886-890
    • Chiba, Y.1    Sakai, H.2    Misawa, M.3
  • 226
    • 0036893225 scopus 로고    scopus 로고
    • Changes in biophysical and biochemical properties of single bronchial smooth muscle cells from asthmatic subjects
    • Ma X, Cheng Z, Kong H, Wang Y, Unruh H, et al. 2002. Changes in biophysical and biochemical properties of single bronchial smooth muscle cells from asthmatic subjects. Am. J. Physiol. Lung Cell Mol. Physiol. 283:L1181-89
    • (2002) Am. J. Physiol. Lung Cell Mol. Physiol , vol.283
    • Ma, X.1    Cheng, Z.2    Kong, H.3    Wang, Y.4    Unruh, H.5
  • 227
    • 0031201731 scopus 로고    scopus 로고
    • Perhaps airway smooth muscle dysfunction contributes to asthmatic bronchial hyperresponsiveness after all
    • Solway J, Fredberg JJ. 1997. Perhaps airway smooth muscle dysfunction contributes to asthmatic bronchial hyperresponsiveness after all. Am. J. Respir. Cell Mol. Biol. 17:144-46
    • (1997) Am. J. Respir. Cell Mol. Biol , vol.17 , pp. 144-146
    • Solway, J.1    Fredberg, J.J.2
  • 228
    • 0020597547 scopus 로고
    • Dose-response curves to inhaled β-adrenoceptor agonists in normal and asthmatic subjects
    • Barnes PJ, Pride NB. 1983. Dose-response curves to inhaled β-adrenoceptor agonists in normal and asthmatic subjects. Br. J. Clin. Pharmacol. 15:677-82
    • (1983) Br. J. Clin. Pharmacol , vol.15 , pp. 677-682
    • Barnes, P.J.1    Pride, N.B.2
  • 231
    • 0032784744 scopus 로고    scopus 로고
    • Role of ERK MAP kinases in responses of cultured human airway smooth muscle cells to IL-1β
    • Laporte JD, Moore PE, Abraham JH, Maksym GN, Fabry B, et al. 1999. Role of ERK MAP kinases in responses of cultured human airway smooth muscle cells to IL-1β. Am. J. Physiol. 277:L943-51
    • (1999) Am. J. Physiol , vol.277
    • Laporte, J.D.1    Moore, P.E.2    Abraham, J.H.3    Maksym, G.N.4    Fabry, B.5
  • 232
    • 0031658992 scopus 로고    scopus 로고
    • Prostanoids mediate IL-1β-induced β-adrenergic hyporesponsiveness in human airway smooth muscle cells
    • Laporte JD, Moore PE, Panettieri RA, Moeller W, Heyder J, Shore SA. 1998. Prostanoids mediate IL-1β-induced β-adrenergic hyporesponsiveness in human airway smooth muscle cells. Am. J. Physiol. 275:L491-501
    • (1998) Am. J. Physiol , vol.275
    • Laporte, J.D.1    Moore, P.E.2    Panettieri, R.A.3    Moeller, W.4    Heyder, J.5    Shore, S.A.6
  • 233
    • 0030005408 scopus 로고    scopus 로고
    • Mechanism of cytokine-induced modulation of β-adrenoceptor responsiveness in airway smooth muscle
    • Hakonarson H, Herrick DJ, Serrano PG, Grunstein MM. 1996. Mechanism of cytokine-induced modulation of β-adrenoceptor responsiveness in airway smooth muscle. J. Clin. Invest. 97:2593-600
    • (1996) J. Clin. Invest , vol.97 , pp. 2593-2600
    • Hakonarson, H.1    Herrick, D.J.2    Serrano, P.G.3    Grunstein, M.M.4
  • 234
    • 0028849232 scopus 로고
    • Mechanism of impaired β-adrenoceptor responsiveness in atopic sensitized airway smooth muscle
    • Hakonarson H, Herrick DJ, Grunstein MM. 1995. Mechanism of impaired β-adrenoceptor responsiveness in atopic sensitized airway smooth muscle. Am. J. Physiol. 269:L645-52
    • (1995) Am. J. Physiol , vol.269
    • Hakonarson, H.1    Herrick, D.J.2    Grunstein, M.M.3
  • 235
    • 0029861298 scopus 로고    scopus 로고
    • Mechanisms of impaired β-adrenoceptor-induced airway relaxation by interleukin-1β in vivo in the rat
    • Koto H, Mak JC, Haddad EB, Xu WB, Salmon M, et al. 1996 Mechanisms of impaired β-adrenoceptor-induced airway relaxation by interleukin-1β in vivo in the rat. J. Clin. Invest. 98:1780-87
    • (1996) J. Clin. Invest , vol.98 , pp. 1780-1787
    • Koto, H.1    Mak, J.C.2    Haddad, E.B.3    Xu, W.B.4    Salmon, M.5
  • 236
    • 0035402376 scopus 로고    scopus 로고
    • Direct effects of interleukin-13 on signaling pathways for physiological responses in cultured human airway smooth muscle cells
    • Laporte JC, Moore PE, Baraldo S, Jouvin MH, Church TL, et al. 2001. Direct effects of interleukin-13 on signaling pathways for physiological responses in cultured human airway smooth muscle cells. Am. J. Respir. Crit. Care Med. 164:141-48
    • (2001) Am. J. Respir. Crit. Care Med , vol.164 , pp. 141-148
    • Laporte, J.C.1    Moore, P.E.2    Baraldo, S.3    Jouvin, M.H.4    Church, T.L.5
  • 237
    • 0141495041 scopus 로고    scopus 로고
    • Regulation of β-adrenergic responses in airway smooth muscle
    • Shore SA, Moore PE. 2003. Regulation of β-adrenergic responses in airway smooth muscle. Respir. Physiol. Neurobiol. 137:179-95
    • (2003) Respir. Physiol. Neurobiol , vol.137 , pp. 179-195
    • Shore, S.A.1    Moore, P.E.2
  • 238
    • 0033927663 scopus 로고    scopus 로고
    • Variation in the interleukin 4-receptor α gene confers susceptibility to asthma and atopy in ethnically diverse populations
    • Ober C, Leavitt SA, Tsalenko A, Howard TD, Hoki DM, et al. 2000. Variation in the interleukin 4-receptor α gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am. J. Hum. Genet. 66:517-26
    • (2000) Am. J. Hum. Genet , vol.66 , pp. 517-526
    • Ober, C.1    Leavitt, S.A.2    Tsalenko, A.3    Howard, T.D.4    Hoki, D.M.5
  • 239
    • 0036080939 scopus 로고    scopus 로고
    • Inhibition of the p38 MAP kinase pathway destabilizes smooth muscle length during physiological loading
    • Lakser OJ, Lindeman RP, Fredberg JJ. 2002. Inhibition of the p38 MAP kinase pathway destabilizes smooth muscle length during physiological loading. Am. J. Physiol. Lung Cell Mol. Physiol. 282:L1117-21
    • (2002) Am. J. Physiol. Lung Cell Mol. Physiol , vol.282
    • Lakser, O.J.1    Lindeman, R.P.2    Fredberg, J.J.3
  • 240
    • 12344323932 scopus 로고    scopus 로고
    • Latrunculin B increases force fluctuation-induced relengthening of ACh-contracted, isotonically shortened canine tracheal smooth muscle
    • Dowell ML, Lakser OJ, Gerthoffer WT, Fredberg JJ, Stelmack GL, et al. 2005. Latrunculin B increases force fluctuation-induced relengthening of ACh-contracted, isotonically shortened canine tracheal smooth muscle. J. Appl. Physiol. 98:489-97
    • (2005) J. Appl. Physiol , vol.98 , pp. 489-497
    • Dowell, M.L.1    Lakser, O.J.2    Gerthoffer, W.T.3    Fredberg, J.J.4    Stelmack, G.L.5


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