Role and regulation of interleukin-1 molecules in pro-asthmatic sensitised airway smooth muscle

European Respiratory Journal

Volumn 24, Issue 4, 2004, Pages 559-567

  Whelan, R ^a   Kim, C ^a   Chen, M ^a   Leiter, J ^a   Grunstein, M M ^a   Hakonarson, H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Airway hyperresponsiveness; Airway smooth muscle; Interleukin 1 axis; Interleukin 5

Indexed keywords

ACETYLCHOLINE; CYTOKINE; IMMUNOGLOBULIN E; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 5; ISOPRENALINE; MESSENGER RNA; RECEPTOR SUBTYPE;

AIRWAY; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; ASTHMA; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; IMMUNOMODULATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RABBIT; REGULATORY MECHANISM; SENSITIZATION; SMOOTH MUSCLE FIBER;

ANIMALS; ASTHMA; BRONCHI; CYTOKINES; HUMANS; IMMUNOGLOBULIN E; INTERLEUKIN-1; INTERLEUKIN-5; MUSCLE, SMOOTH; RABBITS;

EID: 6444237318     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.04.00133803     Document Type: Article

References (36)

1. Bousquet J, Chanez P, Lacoste JY, et al. Eosinophilic inflammation in asthma. N Engl J Med 1990; 323: 1033-1039.
2. Goldie RG, Spina D, Henry PJ, Lulich KM, Paterson JW. In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, beta-adrenoceptor agonists and theophylline. Br J Clin Pharmacol 1986; 22: 669-676.
3. Koning H, Neijens HJ, Baert MR, Oranje AP, Savelkoul HE. T cell subsets and cytokines in allergic and non-allergic children. I. Analysis of IL-4, IFN-gamma and IL-13 mRNA expression and protein production. Cytokine 1997; 9: 416-426.
4. Romagnani S. Biology of human TH1 and TH2 cells. J Clin Immunol 1995; 15: 121-129.
5. Shimoda K, van Deursen J, Sangster MY, et al. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 1996; 380: 630-633.
6. Hakonarson H, Herrick DJ, Serrano PG, Grunstein MM. Autocrine role of interleukin 1beta in altered responsiveness of atopic asthmatic sensitised airway smooth muscle. J Clin Invest 1997; 99: 117-124.
7. Hakonarson H, Whelan R, Leiter J, et al. T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta. J Allergy Clin Immunol 2002; 110: 624-633.
8. Shore SA, Moore PE. Effects of cytokines on contractile and dilator responses of airway smooth muscle. Clin Exp Pharmacol Physiol 2002; 29: 859-866.
9. Hakonarson H, Maskeri N, Carter C, Chuang S, Grunstein MM. Autocrine interaction between IL-5 and IL-1beta mediates altered responsiveness of atopic asthmatic sensitized airway smooth muscle. J Clin Invest 1999; 104: 657-667.
10. Dinarello CA. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int Rev Immunol 1998; 16: 457-499.
11. Borish L, Mascali JJ, Dishuck J, Beam WR, Martin RJ, Rosenwasser U. Detection of alveolar macrophage-derived IL-1 beta in asthma. Inhibition with corticosteroids. J Immunol 1992; 149: 3078-3082.
12. Pujol JL, Cosso B, Daures JP, Clot J, Michel FB, Godard P. Interleukin-1 release by alveolar macrophages in asthmatic patients and healthy subjects. Int Arch Allergy Appl Immunol 1990; 91: 207-210.
13. Kuno K, Matsushima K. The IL-1 receptor signaling pathway. J Leukoc Biol 1994; 56: 542-547.
14. Greenfeder SA, Nunes P, Kwee L, Labow M, Chizzonite RA, Ju G. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J Biol Chem 1995; 270: 13757-13765.
15. Huang J, Gao X, Li S, Cao Z. Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein. Proc Natl Acad Sci USA 1997; 94: 12829-12832.
16. Colotta F, Dower SK, Sims JE, Mantovani A. The type II 'decoy' receptor: a novel regulatory pathway for interleukin 1. Immunol Today 1994; 15: 562-566.
17. Symons JA, Young PR, Duff GW. Soluble type II interleukin 1 (IL-1) receptor binds and blocks processing of IL-1 beta precursor and loses affinity for IL-1 receptor antagonist. Proc Natl Acad Sci USA 1995; 92: 1714-1718.
18. Dripps DJ, Brandhuber BJ, Thompson RC, Eisenberg SP. Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction. J Biol Chem 1991; 266: 10331-10336.
19. Ohlsson K, Bjork P, Bergenfeldt M, Hageman R, Thompson RC. Interleukin-1 receptor antagonist reduces mortality from endotoxin shock. Nature 1990; 348: 550-552.
20. Saperas E, Tache Y. Central interleukin-1 beta-induced inhibition of acid secretion in rats: specificity of action. Life Sci 1993; 52: 785-792.
21. Oshikawa K, Kuroiwa K, Tago K, et al. Elevated soluble ST2 protein levels in sera of patients with asthma with an acute exacerbation. Am J Respir Crit Care Med 2001; 164: 277-281.
22. Hakonarson H, Maskeri N, Carter C, Grunstein MM. Regulation of TH1- and TH2-type cytokine expression and action in atopic asthmatic sensitized airway smooth muscle. J Clin Invest 1999; 103: 1077-1087.
23. Hakonarson H, Carter C, Kim C, Grunstein MM. Altered expression and action of the low-affinity IgE receptor FcepsilonRII (CD23) in asthmatic airway smooth muscle. J Allergy Clin Immunol 1999; 104: 575-584.
24. Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J Exp Med 1996; 183: 195-201.
25. Jablonska E, Jablonski J, Piotrowski L, Grabowska Z. IL-1beta, IL-1Ra and sIL-1RII in the culture supernatants of PMN and PBMC and the serum levels in patients with inflammation and patients with cancer disease of the same location. Immunobiology 2001; 204: 508-516.
26. Amrani Y, Panettieri RA Jr. Cytokines induce airway smooth muscle cell hyperresponsiveness to contractile agonists. Thorax 1998; 53: 713-716.
27. Hakonarson H, Herrick DJ, Grunstein MM. Mechanism of impaired beta-adrenoceptor responsiveness in atopic sensitized airway smooth muscle. Am J Physiol 1995; 269: L645-L652.
28. Hakonarson H, Halapi E, Whelan R, Gulcher J, Stefansson K, Grunstein MM. Association between IL-1beta/TNF-alpha-induced glucocorticoid-sensitive changes in multiple gene expression and altered responsiveness in airway smooth muscle. Am J Respir Cell Mol Biol 2001; 25: 761-771.
29. Nag SS, Xu LJ, Hamid Q, Renzi PM. The effects of IL-5 on airway physiology and inflammation in rats. J Allergy Clin Immunol 2003; 111: 558-566.
30. Mathur M, Herrmann K, Li X, et al. TRFK-5 reverses established airway eosinophilia but not established hyperresponsiveness in a murine model of chronic asthma. Am J Respir Crit Care Med 1999; 159: 580-587.
31. Kline JN, Fisher PA, Monick MM, Hunninghake GW. Regulation of interleukin-1 receptor antagonist by Th1 and Th2 cytokines. Am J Physiol 1995; 269: L92-L98.
32. Gupta K, Bewtra A. IL-1 receptor-type expression in relation to atopy. J Allergy Clin Immunol 1999; 103: 1100-1107.
33. Mao XQ, Kawai M, Yamashita T, et al. Imbalance production between interleukin-1beta (IL-1beta) and IL-1 receptor antagonist (IL-1Ra) in bronchial asthma. Biochem Biophys Res Commun 2000; 276: 607-612.
34. Fanslow WC, Sims JE, Sassenfeld H, et al. Regulation of alloreactivity in vivo by a soluble form of the interleukin-1 receptor. Science 1990; 248: 739-742.
35. Fernandez-Botran R. Soluble cytokine receptors: novel immunotherapeutic agents. Expert Opin Investig Drugs 2000; 9: 497-514.
36. Weckmann AL, Alcocer-Varela J. Cytokine inhibitors in autoimmune disease. Semin Arthritis Rheum 1996; 26: 539-557.