TGF-β1 Modulates Human Airway Smooth-Muscle Cell Proliferation Induced by Mitogens

American Journal of Respiratory Cell and Molecular Biology

Volumn 16, Issue 1, 1997, Pages 85-90

  Cohen, Melissa D ^a   Ciocca, Vincenzo ^a   Panettieri Jr , Reynold A ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; EPIDERMAL GROWTH FACTOR; MITOGENIC AGENT; PROTEIN KINASE (CALCIUM,CALMODULIN); THROMBIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; CYTOLOGY; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; METABOLISM; SMOOTH MUSCLE; TRACHEA;

CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELLS, CULTURED; DNA; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; HUMANS; MITOGENS; MUSCLE, SMOOTH; THROMBIN; TRACHEA; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030641095     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.16.1.8998083     Document Type: Article

References (29)

1. Panettieri, R. A. 1994. Airways smooth muscle cell growth and proliferation. In Airways Smooth Muscle: Development, and Regulation of Contractility. D. Raeburn and M. A. Giembycz, editors. Birkhauser Verlag, Basel, Switzerland. 41-68.
2. De, S., E. T. Zelazny, J. F. Souhrada, and M. Souhrada. 1995. IL-1 beta and IL-6 induce hyperplasia and hypertrophy of cultured guinea pig airway smooth muscle cells. J. Appl. Physiol. 78:1555-1563.
3. Woolcock, A. J. 1988. Asthma - what are the important experiments? State of the art/conference summary. Am. Rev. Respir. Dis. 138:730-744.
4. Dunnill, M. S., G. R. Massarella, and J. A. Anderson. 1969. A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema. Thorax 24:176-179.
5. Hossain, S. 1973. Quantitative measurement of bronchial muscle in asthma. Am. Rev. Respir. Dis. 107:99-109.
6. Huber, H. L., and K. K. Koessler. 1922. The pathology of bronchial asthma. Arch. Intern. Med. 30:690-760.
7. Heard, B. E., and S. Hossain. 1973. Hyperplasia of bronchial muscle in asthma. J. Pathol. 110:319-331.
8. Panettieri, R. A., M. D. Cohen, and G. Bilgen. 1993. Airway smooth muscle cell proliferation is inhibited by microinjection of the catalytic subunit of cAMP dependent protein kinase. Am. Rev. Respir. Dis. 147:A252. (Abstr.)
9. Reddy, K. B., and P. H. Howe. 1993. Transforming growth factor β1-mediated inhibition of smooth muscle cell proliferation is associated with a late G1 cell cycle arrest. J. Cell Physiol. 156:48-55.
10. Kelley, J., E. J. Kovacs, K. Nicholson, and J. P. Fabisiak. 1991. Transforming growth factor-β production by lung macrophages and fibroblasts. Chest 99:85s-86s.
11. Magnan, A., I. Frachon, B. Rain, M. Peuchmaur, G. Monti, B. Lenot, M. Fattal, G. Simonneau, P. Galanaud, and D. Emilie. 1994. Transforming growth factor β in normal human lung: preferential location in bronchial epithelial cells. Thorax 49:789-792.
12. Nogami, M., D. J. Romberger, S. I. Rennard, and M. L. Toews. 1994. TGF-β1 modulates β-adrenergic receptor number and function in cultured human tracheal smooth muscle cells. Am. J. Physiol. 266:L187-L191.
13. Ulich, T. R., S. Yin, K. Guo, E. S. Yi, D. Remick, and J. del Castillo. 1991. Intratracheal injection of endotoxin and cytokines. II. Interleukin-6 and transforming growth factor beta inhibit acute inflammation. Am. J. Pathol. 138:1097-1101.
14. Blenis, J. 1993. Signal transduction via the MAP kinases: proceed at your own RSK. Proc. Natl. Acad. Sci. USA 90:5889-5892.
15. Kelleher, M. D., M. K. Abe, T. S. Chao, M. Jain, J. M. Green, J. Solway, M. R. Rosner, and M. B. Hershenson. 1995. Role of MAP kinase activation in bovine tracheal smooth muscle mitogenesis. Am. J. Physiol. 268: L894-L901.
16. Hershenson, M. B., T. S. Chao, M. K. Abe, I. Gomes, M. D. Kelleher, J. Solway, and M. R. Rosner. 1995. Histamine antagonizes serotonin and growth factor-induced mitogen-activated protein kinase activation in bovine tracheal smooth muscle cells. J. Biol. Chem. 270:19908-19913.
17. Abe, M. K., T. S. Chao, J. Solway, M. R. Rosner, and M. B. Henshenson. 1994. Hydrogen peroxide stimulates mitogen-activated protein kinase in bovine tracheal myocytes: implications for human airway disease. Am. J. Respir. Cell Mol. Biol. 11:577-585.
18. Panettieri, R. A., L. R. DePalo, R. K. Murray, P. A. Yadvish, and M. I. Kotlikoff. 1989. A human airway smooth muscle cell line that retains physiological responsiveness. Am. J. Physiol. Cell 256:C329-C335.
19. Lazaar, A. L., S. M. Albelda, J. M. Pilewski, B. Brennan, E. Puré, and R. A. Panettieri. 1994. T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis. J. Exp. Med. 180:807-815.
20. Panettieri, R. A., P. A. Yadvish, A. M. Kelly, N. A. Rubinstein, and M. I. Kotlikoff. 1990. Histamine stimulates proliferation of airway smooth muscle and induces c-fos expression. Am. J. Physiol. Lung Cell Mol. Physiol. 259:L365-L371.
21. Panettieri, R. A., A. Eszterhas, and R. K. Murray. 1992. Agonist-induced proliferation of airway smooth muscle cells is mediated by alterations in cytosolic calcium. Am. Rev. Respir. Dis. 145:A15. (Abstr.)
22. Massagué, J. 1990. The transforming growth factor-beta family. Annu. Rev. Cell Biol. 6:597-641.
23. Massagué, J. 1992. Receptors for the TGF-beta family. Cell 69:1067-1070.
24. mapk in proliferating cultures of epithelial cells. J. Biol. Chem. 270:7117-7124.
25. Wrana, J. L., L. Attisano, R. Wieser, F. Ventura, and J. Massagué. 1994. Mechanism of activation of the TGF-beta receptor. Nature 370:341-347.
26. Hopkin, K. 1994. The TGF-β1 signaling pathway: a new model with no middle. J. NIH Res. 6:40-42.
27. Panettieri, R. A., I. P. Hall, C. S. Maki, and R. K. Murray. 1995. α-Thrombin increases cytosolic calcium and induces human airway smooth muscle cell proliferation. Am. J. Respir. Cell Mol. Biol. 13:205-216.
28. Johnson, G. L., and R. R. Vaillancourt. 1994. Sequential protein kinase reactions controlling cell growth and differentiation. Curr. Opin. Cell Biol. 6:230-238.
29. Molloy, C. J., J. E. Pawlowski, D. S. Taylor, C. E. Turner, H. Weber, M. Peluso, and S. M. Seiler. 1996. Thrombin receptor activation elicits rapid protein tyrosine phosphorylation and stimulation of the raf-1/MAP kinase pathway preceding delayed mitogenesis in cultured rat aortic smooth muscle cells. Evidence for an obligate autocrine mechanism promoting cell proliferation induced by G protein-coupled receptor agonists. J. Clin. Invest. 97:1173-1183.