Myofibroblast Involvement in the Allergen-induced Late Response in Mild Atopic Asthma

American Journal of Respiratory Cell and Molecular Biology

Volumn 16, Issue 6, 1997, Pages 664-673

  Gizycki, Mariusz J ^b   Ädelroth, Ellinor ^b   Rogers, Andrew V ^b   O'Byrne, Paul M ^b   Jeffery, Peter K ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BRONCHUS;

ALLERGEN; CONTRACTILE PROTEIN;

ADULT; ARTICLE; ASTHMA; BASEMENT MEMBRANE; BIOPSY; BRONCHOSCOPY; BRONCHUS; CELL COUNT; CELL MOTION; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; ELECTRON MICROSCOPY; EOSINOPHIL; FEMALE; FIBROBLAST; HUMAN; IMMUNOLOGY; MALE; PATHOLOGY; ULTRASTRUCTURE;

ADULT; ALLERGENS; ASTHMA; BASEMENT MEMBRANE; BIOPSY; BRONCHI; BRONCHOSCOPY; CELL COUNT; CELL MOVEMENT; CONTRACTILE PROTEINS; EOSINOPHILS; FEMALE; FIBROBLASTS; HUMANS; MALE; MICROSCOPY, ELECTRON;

EID: 0031156745     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.16.6.9191468     Document Type: Article

References (29)

1. Dunnill, M. S., G. R. Massarella, and J. A. Anderson. 1969. A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema. Thorax 24:176-179.
2. Azzawi, M., P. W. Johnston, S. Majumdar, A. B. Kay, and P. K. Jeffery. 1992. T lymphocytes and activated eosinophils in asthma and cystic fibrosis. Am. Rev. Respir. Dis. 145:1477-1482.
3. Jeffery, P. K., A. Wardlaw, F. C. Nelson, J. V. Collins, and A. B. Kay. 1989. Bronchial biopsies in asthma: an ultrastructural quantification study and correlation with hyperreactivity. Am. Rev. Respir. Dis. 140:1745-1753.
4. Beasley, R., W. Roche, J. A. Roberts, and S. T. Holgate. 1989. Cellular events in the bronchi in mild asthma and after bronchial provocation. Am. Rev. Respir. Dis. 139:806-817.
5. Laitinen, L. A., A. Laitinen, and T. Haahtela. 1993. Airway mucosal inflammation even in patients with newly diagnosed asthma. Am. Rev. Respir. Dis. 147:697-704.
6. Azzawi, M., B. Bradley, P. K. Jeffery, A. J. Frew, A. J. Wardlaw, B. Assoufi, J. V. Collins, S. Durham, and A. B. Kay. 1990. Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am. Rev. Respir. Dis. 142:1407-1413.
7. Bradley, B. L., M. Azzawi, M. Jacobson, B. Assoufi, J. V. Collins, A.-M. A. Irani, L. B. Schwartz, S. R. Durham, P. K. Jeffery, and A. B. Kay. 1991. Eosinophils, T-lymphocytes, mast cells, neutrophils and macrophages in bronchial biopsies from atopic asthmatics: comparison with atopic non-asthma and relationship to bronchial hyperresponsiveness. J. Allergy Clin. Immunol. 88:661-674.
8. Roche, W. R., R. Beasley, J. H. Williams, and S. T. Holgate. 1989. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1:520-523.
9. Brewster, C. E. P., P. H. Howarth, R. Djukanovic, J. Wilson, S. T. Holgate, and W. R. Roche. 1990. Myofibroblasts and subepithelial fibrosis in bronchial asthma. Am. J. Respir. Cell Mol. Biol. 3:507-511.
10. Woolley, K. L., E. Adelroth, M. J. Woolley, M. Jordana, and P. M. O'Byrne. 1995. Effects of allergen challenge on eosinophils, eosinophil cationic protein and granulocyte-macrophage colony-stimulating factor in mild asthmatics. Am. J. Respir. Crit. Care Med. 151:1915-1924.
11. Cockcroft, D. W. 1985. Measurement of airway responsiveness to inhaled histamine or methacholine; method of continuous aerosol generation and tidal breathing inhalation. In Airway Responsiveness: Measurement and Interpretation. F. E. Hargreave and A. J. Woolcock, editors. Astra Pharmaceuticals Canada, Mississauga, ON. 22-28.
12. NHLBI Workshop Summary. 1985. Summary and recommendations of a workshop on the investigative use of fiberoptic bronchoscopy and bronchoalveolar lavage in asthmatics. Am. Rev. Respir. Dis. 132:180-182.
13. Schmitt-Graff, A., A. Desmouliere, and G. Gabbiani. 1994. Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity. Virchows Arch. [B] 425:3-24.
14. Lipper, S., L. B. Kahn, and R. L. Reddick. 1980. The myofibroblast. Pathol. Annu. 15(Part 1):409-441.
15. Jeffery, P. K. 1992. Pathology of asthma. Br. Med. Bull. 48:23-39.
16. Bhawan, J., and G. Majno. 1989. The myofibroblast: possible derivation from macrophages in xanthogranuloma. Am. J. Dermatopathol. 11:255.
17. Gown, A. M. 1990. The mysteries of the myofibroblast (partially) unmasked. Lab. Invest. 63:1-3.
18. Ryan, G. B., W. J. Cliff, G. Gabbiani, C. Irle, D. Montandon, P. R. Statkov, and G. Majno. 1974. Myofibroblasts in human granulation tissue. Hum. Pathol 5:55-67.
19. Seemayer, T. A., R. Lagace, W. Schurch, and W. L. Thelmo. 1980. The myofibroblast: biologic, pathologic and theoretical considerations. Pathol. Annu. 15(Part 1):443-470.
20. Ross, R., and S. J. Klebanoff. 1967. Fine structural changes in uterine smooth muscle and fibroblasts in response to estrogen. J. Cell Biol. 32:155-167.
21. Severs, N. J., and H. Robenek. 1992. Constituents of the arterial wall and atherosclerotic plaque: an introduction to atherosclerosis. In Cell Interactions in Atherosclerosis. H. Robenek and N. J. Severs, editors. CRC Press, Boca Raton, FL. 1-49.
22. Hirst, S. J. 1996. Airway smooth muscle cell culture: application to studies of airway wall remodelling and phenotype plasticity in asthma. Eur. Respir. J. 9:808-820.
23. Kapanci, Y., A. Assimacopoulos, C. Irle, A. Zwahlen, and G. Gabbiani. 1974. "Contractile interstitial cells" in pulmonary alveolar septa: ultrastructural, immunofluorescence and in vitro studies: a possible regulation of ventilation/perfusion ratio. J. Cell Biol. 60:375-395.
24. Kocher, O., and G. Gabbiani. 1986. Cytoskeletal features of normal and atheromatous human arterial smooth muscle cells. Hum. Pathol. 17:875-880.
25. Jeffery, P. K. 1994. Structural changes in asthma. In Airways and Vascular Remodelling in Asthma and Cardiovascular Disease. C. Page and J. Black, editors. Academic Press, London. 3-19.
26. Campbell, J. H., O. Kocher, O. Skalli, G. Gabbiani, and G. R. Campbell. 1989. Cytodifferentiation and expression of α-smooth muscle actin mRNA and protein during primary culture of aortic smooth muscle cells: correlation with cell density and proliferative state. Arteriosclerosis 9:633-643.
27. Rennick, R. E., J.-L. Connat, G. Burnstock, S. Rothery, N. J. Severs, and C. R. Green. 1993. Expression of connexin43 gap junctions between cultured vascular smooth muscle cells is dependent upon phenotype. Cell Tiss. Res. 271:323-332.
28. O'Shea, J. D. 1970. An ultrastructural study of smooth muscle-like cells in the theca externa of ovarian follicles in the rat. Anal. Rec. 167:127-131.
29. Carroll, N., A. Elliot, A. Morton, and A. James. 1993. The structure of large and small airways in nonfatal and fatal asthma. Am. Rev. Respir. Dis. 147:405-410.