-
1
-
-
0025342014
-
Abnormalities in airway smooth muscle in fatal asthma
-
Bai, T.R. 1990. Abnormalities in airway smooth muscle in fatal asthma. Am. Rev. Respir. Dis. 141:552-557.
-
(1990)
Am. Rev. Respir. Dis.
, vol.141
, pp. 552-557
-
-
Bai, T.R.1
-
2
-
-
0022978869
-
In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, beta-adrenoceptor agonists and theophylline
-
Goldie, R.G., Spina, D., Henry, P.J., Lulich, K.M., and Paterson, J.W. 1986. In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, beta-adrenoceptor agonists and theophylline. Br. J. Clin. Pharmacol. 22:669-676.
-
(1986)
Br. J. Clin. Pharmacol.
, vol.22
, pp. 669-676
-
-
Goldie, R.G.1
Spina, D.2
Henry, P.J.3
Lulich, K.M.4
Paterson, J.W.5
-
3
-
-
0025037094
-
Eosinophilic inflammation in asthma
-
Bousquet, J., et al. 1990. Eosinophilic inflammation in asthma. N. Engl. J. Med. 323:1033-1039.
-
(1990)
N. Engl. J. Med.
, vol.323
, pp. 1033-1039
-
-
Bousquet, J.1
-
4
-
-
0025324736
-
Mucosal inflammation in asthma
-
Djukanovic, R., et al. 1990. Mucosal inflammation in asthma. Am. Rev. Respir. Dis. 142:434-457.
-
(1990)
Am. Rev. Respir. Dis.
, vol.142
, pp. 434-457
-
-
Djukanovic, R.1
-
5
-
-
0031150153
-
T cells subsets and cytokines in allergic and non-allergic children. II. Analysis and IL-5 and IL-10 mRNA expression and protein production
-
Koning, H., Neijens, H.J., Baert, M.R., Oranje, A.P., and Savelkoul, H.F. 1997. T cells subsets and cytokines in allergic and non-allergic children. II. Analysis and IL-5 and IL-10 mRNA expression and protein production. Cytokine. 9:427-436.
-
(1997)
Cytokine
, vol.9
, pp. 427-436
-
-
Koning, H.1
Neijens, H.J.2
Baert, M.R.3
Oranje, A.P.4
Savelkoul, H.F.5
-
6
-
-
0025905108
-
Regulation of human IgE synthesis
-
Gascan, H., et al. 1991. Regulation of human IgE synthesis. Clin. Exp. Allergy. 21(Suppl. 1):162-166.
-
(1991)
Clin. Exp. Allergy
, vol.21
, Issue.SUPPL. 1
, pp. 162-166
-
-
Gascan, H.1
-
7
-
-
0028978680
-
Biology of human TH1 and TH2 cells
-
Romagnani, S. 1995. Biology of human TH1 and TH2 cells. J. Clin. Immunol. 15:121-129.
-
(1995)
J. Clin. Immunol.
, vol.15
, pp. 121-129
-
-
Romagnani, S.1
-
9
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda, K., et al. 1996. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature. 380:630-633.
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
-
10
-
-
0030028768
-
Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
-
Foster, P.S., Hogan, S.P., Ramsay, A.J., Matthaei, K.I., and Young, I.G. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med. 183:195-201.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 195-201
-
-
Foster, P.S.1
Hogan, S.P.2
Ramsay, A.J.3
Matthaei, K.I.4
Young, I.G.5
-
11
-
-
0031665966
-
An essential role for interleukin-5 and eosinophils in helminth-induced airway hyperresponsiveness
-
Hall, L.R., Mehlotra, R.K., Higgins, A.W., Haxhiu, M.A., and Pearlman, E. 1998. An essential role for interleukin-5 and eosinophils in helminth-induced airway hyperresponsiveness. Infect. Immun. 66:4425-4430.
-
(1998)
Infect. Immun.
, vol.66
, pp. 4425-4430
-
-
Hall, L.R.1
Mehlotra, R.K.2
Higgins, A.W.3
Haxhiu, M.A.4
Pearlman, E.5
-
12
-
-
0031816893
-
Allergen-induced proliferation and interleukin-5 production by bronchoalveolar lavage and blood T cells after segmental allergen challenge
-
Till, S.J., et al. 1998. Allergen-induced proliferation and interleukin-5 production by bronchoalveolar lavage and blood T cells after segmental allergen challenge. Am. J. Respir. Crit. Care Med. 158:404-411.
-
(1998)
Am. J. Respir. Crit. Care Med.
, vol.158
, pp. 404-411
-
-
Till, S.J.1
-
13
-
-
0028075824
-
Cytokine production by epithelial cells
-
Stadnyk, A.W. 1994. Cytokine production by epithelial cells. FASEB J. 8:1041-1047.
-
(1994)
FASEB J.
, vol.8
, pp. 1041-1047
-
-
Stadnyk, A.W.1
-
14
-
-
0025109273
-
Cytokines and the skin
-
Luger, T.A., et al. 1990. Cytokines and the skin. Curr. Probl. Dermatol. 19:35-49.
-
(1990)
Curr. Probl. Dermatol.
, vol.19
, pp. 35-49
-
-
Luger, T.A.1
-
15
-
-
0028583097
-
Immune-inflammatory functions of fibroblasts
-
Jordana, M., Sarnstrand, B., Sime, P.J., and Ramis, I. 1994. Immune-inflammatory functions of fibroblasts. Eur. Respir. J. 7:2212-2222.
-
(1994)
Eur. Respir. J.
, vol.7
, pp. 2212-2222
-
-
Jordana, M.1
Sarnstrand, B.2
Sime, P.J.3
Ramis, I.4
-
16
-
-
0026026809
-
Keratinocytes as initiators of inflammation
-
Barker, J.N., Mitra, R.S., Griffiths, C.E., Dixit, V.M., and Nickoloff, B.J. 1991. Keratinocytes as initiators of inflammation. Lancet. 337:211-214.
-
(1991)
Lancet
, vol.337
, pp. 211-214
-
-
Barker, J.N.1
Mitra, R.S.2
Griffiths, C.E.3
Dixit, V.M.4
Nickoloff, B.J.5
-
17
-
-
0031034464
-
Autocrine role of interleukin 1beta in altered responsiveness of atopic asthmatic sensitized airway smooth muscle
-
Hakonarson, H., Herrick, D.J., Serrano, P.G., and Grunstein, M.M. 1997. Autocrine role of interleukin 1beta in altered responsiveness of atopic asthmatic sensitized airway smooth muscle. J. Clin. Invest. 99:117-124.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 117-124
-
-
Hakonarson, H.1
Herrick, D.J.2
Serrano, P.G.3
Grunstein, M.M.4
-
18
-
-
0032943560
-
Regulation of TH1- and TH2-type cytokine expression and action in atopic asthmatic sensitized airway smooth muscle
-
Hakonarson, H., Maskeri, N., Carter, C., and Grunstein, M.M. 1999. Regulation of TH1- and TH2-type cytokine expression and action in atopic asthmatic sensitized airway smooth muscle. J. Clin. Invest. 103:1077-1087.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1077-1087
-
-
Hakonarson, H.1
Maskeri, N.2
Carter, C.3
Grunstein, M.M.4
-
19
-
-
0028849232
-
Mechanism of impaired beta-adrenoceptor responsiveness in atopic sensitized airway smooth muscle
-
Hakonarson, H., Herrick, D.J., and Grunstein, M.M. 1995. Mechanism of impaired beta-adrenoceptor responsiveness in atopic sensitized airway smooth muscle. Am. J. Physiol. 269:L645-L652.
-
(1995)
Am. J. Physiol.
, vol.269
-
-
Hakonarson, H.1
Herrick, D.J.2
Grunstein, M.M.3
-
21
-
-
0023433306
-
Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5)
-
Campbell, H.D., et al. 1987. Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5). Proc. Natl. Acad. Sci. USA. 84:6629-6633.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 6629-6633
-
-
Campbell, H.D.1
-
22
-
-
0344304251
-
-
US patent 5,122,459. Issued June 16, 1992
-
Conlon, P.J., III, Cosman, D.J., Grabstein, D.J., Mopp, T.P., Kronham, S.R., Larsen, A.D., March, C.J., Price, V.L., and Current, D.P., inventors. Gene encoding biologicallyactive human interleukin 1. US patent 5,122,459. Issued June 16, 1992.
-
Gene Encoding Biologicallyactive Human Interleukin 1
-
-
Conlon P.J. III1
Cosman, D.J.2
Grabstein, D.J.3
Mopp, T.P.4
Kronham, S.R.5
Larsen, A.D.6
March, C.J.7
Price, V.L.8
Current, D.P.9
-
23
-
-
0027319950
-
Identification of a transcript that is down-regulated in senescent human fibroblasts. Cloning, sequence analysis, and regulation of the human L7 ribosomal protein gene
-
Seshadri, T., Uzman, J.A., Oshima, J., and Campisi, J. 1993. Identification of a transcript that is down-regulated in senescent human fibroblasts. Cloning, sequence analysis, and regulation of the human L7 ribosomal protein gene. J. Biol. Chem. 268:18474-18480.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18474-18480
-
-
Seshadri, T.1
Uzman, J.A.2
Oshima, J.3
Campisi, J.4
-
24
-
-
0027583806
-
Cytokines contribute to airway dysfunction in antigen-challenged guinea pigs: Inhibition of airway hyperreactivity, pulmonary eosinophil accumulation, and tumor necrosis factor generation by pretreatment with an interleukin-1 receptor antagonist
-
Watson, M.L., Smith, D., Bourne, A.D., Thompson, R.C., and Westwick, J. 1992. Cytokines contribute to airway dysfunction in antigen-challenged guinea pigs: inhibition of airway hyperreactivity, pulmonary eosinophil accumulation, and tumor necrosis factor generation by pretreatment with an interleukin-1 receptor antagonist. Am. J. Respir. Cell Mol. Biol. 8:365-369.
-
(1992)
Am. J. Respir. Cell Mol. Biol.
, vol.8
, pp. 365-369
-
-
Watson, M.L.1
Smith, D.2
Bourne, A.D.3
Thompson, R.C.4
Westwick, J.5
-
25
-
-
0027551037
-
Organ culture with proinflammatory cytokines reproduces impairment of the beta-adrenoceptor-mediated relaxation in tracheas of a guinea pig antigen model
-
Wills-Karp, et al. 1993. Organ culture with proinflammatory cytokines reproduces impairment of the beta-adrenoceptor-mediated relaxation in tracheas of a guinea pig antigen model. Am. J. Respir. Cell Mol. Biol. 8:153-159.
-
(1993)
Am. J. Respir. Cell Mol. Biol.
, vol.8
, pp. 153-159
-
-
Wills-Karp1
-
26
-
-
0030005408
-
Mechanism of cytokine-induced modulation of beta-adrenoceptor responsiveness in airway smooth muscle
-
Hakonarson, H., Herrick, D.J., Serrano, P.G., and Grunstein, M.M. 1996. Mechanism of cytokine-induced modulation of beta-adrenoceptor responsiveness in airway smooth muscle. J. Clin. Invest. 97:2593-2600.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2593-2600
-
-
Hakonarson, H.1
Herrick, D.J.2
Serrano, P.G.3
Grunstein, M.M.4
-
27
-
-
0026610142
-
Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma
-
Robinson, D.S., et al. 1992. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med. 326:298-304.
-
(1992)
N. Engl. J. Med.
, vol.326
, pp. 298-304
-
-
Robinson, D.S.1
-
28
-
-
0026666718
-
Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage
-
Walker, C., et al. 1992. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am. Rev. Respir. Dis. 146:109-115.
-
(1992)
Am. Rev. Respir. Dis.
, vol.146
, pp. 109-115
-
-
Walker, C.1
-
29
-
-
0028216039
-
Detection of cytokines and their cell sources in bronchial biopsy specimens from asthmatic patients. Relationship to atopic status, symptoms, and level of airway hyperresponsiveness
-
Ackerman, V., et al. 1994. Detection of cytokines and their cell sources in bronchial biopsy specimens from asthmatic patients. Relationship to atopic status, symptoms, and level of airway hyperresponsiveness. Chest. 105:687-696.
-
(1994)
Chest
, vol.105
, pp. 687-696
-
-
Ackerman, V.1
-
30
-
-
0025760379
-
Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma
-
Hamid, Q., et al. 1991. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J. Clin. Invest. 87:1541-1546.
-
(1991)
J. Clin. Invest.
, vol.87
, pp. 1541-1546
-
-
Hamid, Q.1
-
31
-
-
0029302202
-
Phenotype of cells expressing mRNA for TH2-rype (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects
-
Ying, S., Durham, S.R., Corrigan, C.J., Hamid, Q., and Kay, A.B. 1995. Phenotype of cells expressing mRNA for TH2-rype (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects. Am. J. Respir. Cell Mol. Biol. 12:477-487.
-
(1995)
Am. J. Respir. Cell Mol. Biol.
, vol.12
, pp. 477-487
-
-
Ying, S.1
Durham, S.R.2
Corrigan, C.J.3
Hamid, Q.4
Kay, A.B.5
-
32
-
-
0027183057
-
Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-gamma cytokine gene expression
-
Robinson, D., et al. 1993. Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-gamma cytokine gene expression. Am. Rev. Respir. Dis. 148:401-406.
-
(1993)
Am. Rev. Respir. Dis.
, vol.148
, pp. 401-406
-
-
Robinson, D.1
-
33
-
-
0030945106
-
Th1 and Th2 CD4+ cells in the pathogenesis of allergic diseases
-
Umetsu, D.T., and DeKruyff, R.H. 1997. Th1 and Th2 CD4+ cells in the pathogenesis of allergic diseases [review]. Proc. Soc. Exp. Biol. Med. 215:11-20.
-
(1997)
Proc. Soc. Exp. Biol. Med.
, vol.215
, pp. 11-20
-
-
Umetsu, D.T.1
DeKruyff, R.H.2
-
34
-
-
0029038207
-
sVCAM-1 levels after segmental antigen challenge correlate with eosinophil influx, IL-4 and IL-5 production, and the late phase response
-
Zangrilli, J.G., et al. 1995. sVCAM-1 levels after segmental antigen challenge correlate with eosinophil influx, IL-4 and IL-5 production, and the late phase response. Am. J. Respir. Crit. Care Med. 151:1346-1353.
-
(1995)
Am. J. Respir. Crit. Care Med.
, vol.151
, pp. 1346-1353
-
-
Zangrilli, J.G.1
-
35
-
-
0030028768
-
Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
-
Foster, P.S., Hogan, S.P., Ramsay, A.J., Matthaei, K.I., and Young, I.G. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med. 183:195-201.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 195-201
-
-
Foster, P.S.1
Hogan, S.P.2
Ramsay, A.J.3
Matthaei, K.I.4
Young, I.G.5
-
36
-
-
17444454662
-
Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma
-
Lee, J.J., et al. 1997. Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma. J. Exp. Med. 185:2143-2156.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 2143-2156
-
-
Lee, J.J.1
-
37
-
-
0000965148
-
TRFK-5 reverses established airway eosinophilia but not established hyperresponsiveness in a murine model of chronic asthma
-
Mathur, M., et al. 1999. TRFK-5 reverses established airway eosinophilia but not established hyperresponsiveness in a murine model of chronic asthma. Am. J. Respir. Crit. Care Med. 159:580-587.
-
(1999)
Am. J. Respir. Crit. Care Med.
, vol.159
, pp. 580-587
-
-
Mathur, M.1
|