-
1
-
-
0027450410
-
A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity
-
Carpenter C.L., Auger K.R., Duckworth B.C., Hou W., Schaffhausen B., Cantley L.C. A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity. Mol. Cell. Biol. 13:1993;1657-1665
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 1657-1665
-
-
Carpenter, C.L.1
Auger, K.R.2
Duckworth, B.C.3
Hou, W.4
Schaffhausen, B.5
Cantley, L.C.6
-
2
-
-
0027953284
-
PI 3-kinase is a dual specificity enzyme: Autoregulation by an intrinsic protein-serine kinase activity
-
Dhand R., Hiles I., Panayotou G., Roche S., Fry M.J., Gout I., Totty N.F., Truong O., Vicendo P., Yonezawa K., Kasuga M., Courtneidge S.A., Waterfield M.D. PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity. EMBO J. 13:1994;522-533
-
(1994)
EMBO J.
, vol.13
, pp. 522-533
-
-
Dhand, R.1
Hiles, I.2
Panayotou, G.3
Roche, S.4
Fry, M.J.5
Gout, I.6
Totty, N.F.7
Truong, O.8
Vicendo, P.9
Yonezawa, K.10
Kasuga, M.11
Courtneidge, S.A.12
Waterfield, M.D.13
-
3
-
-
0034283188
-
Comparison of the kinetic properties of the lipid- and protein-kinase activities of the p110α and p110β catalytic subunits of class-Ia phosphoinositide 3-kinases
-
Beeton C.A., Chance E.M., Foukas L.C., Shepherd P.R. Comparison of the kinetic properties of the lipid- and protein-kinase activities of the p110α and p110β catalytic subunits of class-Ia phosphoinositide 3-kinases. Biochem. J. 350:2000;353-359
-
(2000)
Biochem. J.
, vol.350
, pp. 353-359
-
-
Beeton, C.A.1
Chance, E.M.2
Foukas, L.C.3
Shepherd, P.R.4
-
4
-
-
1642499409
-
Regulation of phosphoinositide 3-kinase by its intrinsic serine kinase activity in vivo
-
Foukas L.C., Beeton C.A., Jensen J., Phillips W.A., Shepherd P.R. Regulation of phosphoinositide 3-kinase by its intrinsic serine kinase activity in vivo. Mol. Cell. Biol. 24:2004;966-975
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 966-975
-
-
Foukas, L.C.1
Beeton, C.A.2
Jensen, J.3
Phillips, W.A.4
Shepherd, P.R.5
-
5
-
-
0037020224
-
Direct effects of caffeine and theophylline on p110δ and other phosphoinositide 3-kinases; Differential effects on lipid kinase and protein kinase activities
-
Foukas L.C., Daniele N., Ktori C., Anderson K.E., Jensen J., Shepherd P.R. Direct effects of caffeine and theophylline on p110δ and other phosphoinositide 3-kinases; differential effects on lipid kinase and protein kinase activities. J. Biol. Chem. 277:2002;37124-37130
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37124-37130
-
-
Foukas, L.C.1
Daniele, N.2
Ktori, C.3
Anderson, K.E.4
Jensen, J.5
Shepherd, P.R.6
-
6
-
-
0033104502
-
Autophosphorylation of p110δ phosphoinositide 3-kinase: A new paradigm for the regulation of lipid kinases in vitro and in vivo
-
Vanhaesebroeck B., Higashi K., Raven C., Welham M., Anderson S., Brennan P., Ward S.G., Waterfield M.D. Autophosphorylation of p110δ phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo. EMBO J. 18:1999;1292-1302
-
(1999)
EMBO J.
, vol.18
, pp. 1292-1302
-
-
Vanhaesebroeck, B.1
Higashi, K.2
Raven, C.3
Welham, M.4
Anderson, S.5
Brennan, P.6
Ward, S.G.7
Waterfield, M.D.8
-
7
-
-
0037501368
-
Identification and characterization of the autophosphorylation sites of phosphoinositide 3-kinase isoforms beta and gamma
-
Czupalla C., Culo M., Muller E.C., Brock C., Reusch H.P., Spicher K., Krause E., Nurnberg B. Identification and characterization of the autophosphorylation sites of phosphoinositide 3-kinase isoforms beta and gamma. J. Biol. Chem. 278:2003;11536-11545
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11536-11545
-
-
Czupalla, C.1
Culo, M.2
Muller, E.C.3
Brock, C.4
Reusch, H.P.5
Spicher, K.6
Krause, E.7
Nurnberg, B.8
-
8
-
-
0030920653
-
Lipid kinase and protein kinase activities of G-protein coupled phosphoinositide 3-kinase γ: SStructure-activity analysis and interactions with wortmannin
-
Stoyanova S., Bulgarelli-Leva G., Kirsch C., Hanck T., Klinger R., Wetzker R., Wymann M.P. Lipid kinase and protein kinase activities of G-protein coupled phosphoinositide 3-kinase γ: structure-activity analysis and interactions with wortmannin. Biochem. J. 324:1997;489-495
-
(1997)
Biochem. J.
, vol.324
, pp. 489-495
-
-
Stoyanova, S.1
Bulgarelli-Leva, G.2
Kirsch, C.3
Hanck, T.4
Klinger, R.5
Wetzker, R.6
Wymann, M.P.7
-
9
-
-
0032737893
-
Differential regulation of lipid and protein kinase activities of phosphoinositide 3-kinase gamma in vitro
-
Bondev A., Rubio I., Wetzker R. Differential regulation of lipid and protein kinase activities of phosphoinositide 3-kinase gamma in vitro. Biol. Chem. 380:1999;1337-1340
-
(1999)
Biol. Chem.
, vol.380
, pp. 1337-1340
-
-
Bondev, A.1
Rubio, I.2
Wetzker, R.3
-
10
-
-
0028018858
-
The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1
-
Lam K., Carpenter C.L., Ruderman N.B., Friel J.C., Kelly K.L. The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. J. Biol. Chem. 269:1994;20648-20652
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 20648-20652
-
-
Lam, K.1
Carpenter, C.L.2
Ruderman, N.B.3
Friel, J.C.4
Kelly, K.L.5
-
11
-
-
0027967958
-
Insulin receptor substrate-1 is phosphorylated by the serine kinase activity of phosphatidylinositol 3-kinase
-
Tanti J.F., Gremeaux T., Obberghen E.V., Marchand-Brustel Y.L. Insulin receptor substrate-1 is phosphorylated by the serine kinase activity of phosphatidylinositol 3-kinase. Biochem. J. 304:1994;17-21
-
(1994)
Biochem. J.
, vol.304
, pp. 17-21
-
-
Tanti, J.F.1
Gremeaux, T.2
Obberghen, E.V.3
Marchand-Brustel, Y.L.4
-
12
-
-
0031093545
-
Activation of the phosphatidylinositol 3-kinase serine kinase by IFN-α
-
Uddin S., Fish E.N., Sher D.A., Gardziola C., White M.F., Platanias L.C. Activation of the phosphatidylinositol 3-kinase serine kinase by IFN-α J. Immunol. 158:1997;2390-2397
-
(1997)
J. Immunol.
, vol.158
, pp. 2390-2397
-
-
Uddin, S.1
Fish, E.N.2
Sher, D.A.3
Gardziola, C.4
White, M.F.5
Platanias, L.C.6
-
13
-
-
0034616384
-
Phosphorylation of PDE3B by phosphatidylinositol 3-kinase associated with the insulin receptor
-
Rondinone C.M., Carvalho E., Rahn T., Manganiello V.C., Degerman E., Smith U.P. Phosphorylation of PDE3B by phosphatidylinositol 3-kinase associated with the insulin receptor. J. Biol. Chem. 275:2000;10093-10098
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10093-10098
-
-
Rondinone, C.M.1
Carvalho, E.2
Rahn, T.3
Manganiello, V.C.4
Degerman, E.5
Smith, U.P.6
-
14
-
-
0032834055
-
EIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
-
Gingras A.C., Raught B., Sonenberg N. eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu. Rev. Biochem. 68:1999;913-963
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 913-963
-
-
Gingras, A.C.1
Raught, B.2
Sonenberg, N.3
-
15
-
-
0030666262
-
Molecular mechanisms for the control of translation by insulin
-
Proud C.G., Denton R.M. Molecular mechanisms for the control of translation by insulin. Biochem. J. 328:1997;329-341
-
(1997)
Biochem. J.
, vol.328
, pp. 329-341
-
-
Proud, C.G.1
Denton, R.M.2
-
16
-
-
0034057277
-
Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression
-
Mothe-Satney I., Yang D., Fadden P., Haystead T.A.J., Lawrence J.C. Jr. Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression. Mol. Cell. Biol. 20:2000;3558-3567
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3558-3567
-
-
Mothe-Satney, I.1
Yang, D.2
Fadden, P.3
Haystead, T.A.J.4
Lawrence Jr., J.C.5
-
17
-
-
0030881836
-
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin
-
Brunn G.J., Hudson C.C., Sekulic A., Williams J.M., Hosoi H., Houghton P.J., Lawrence J.C., Abraham R.T. Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. Science. 277:1997;99-101
-
(1997)
Science
, vol.277
, pp. 99-101
-
-
Brunn, G.J.1
Hudson, C.C.2
Sekulic, A.3
Williams, J.M.4
Hosoi, H.5
Houghton, P.J.6
Lawrence, J.C.7
Abraham, R.T.8
-
18
-
-
0031453135
-
The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus
-
Brunn G.J., Fadden P., Haystead T.A., Lawrence J.C. Jr. The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus. J. Biol. Chem. 272:1997;32547-32550
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32547-32550
-
-
Brunn, G.J.1
Fadden, P.2
Haystead, T.A.3
Lawrence Jr., J.C.4
-
19
-
-
0032539664
-
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
-
Burnett P.E., Burrow R.K., Cohen N.A., Snyder S.H., Sabatini D.M. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc. Natl. Acad. Sci. USA. 95:1998;1432-1437
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1432-1437
-
-
Burnett, P.E.1
Burrow, R.K.2
Cohen, N.A.3
Snyder, S.H.4
Sabatini, D.M.5
-
20
-
-
0032849890
-
Dissociation of the eukaryotic initiation factor-4E/4E-BP1 complex involves phosphorylation of 4E-BP1 by an mTOR-associated kinase
-
Heesom K.J., Denton R.M. Dissociation of the eukaryotic initiation factor-4E/4E-BP1 complex involves phosphorylation of 4E-BP1 by an mTOR-associated kinase. FEBS Lett. 457:1999;489-493
-
(1999)
FEBS Lett.
, vol.457
, pp. 489-493
-
-
Heesom, K.J.1
Denton, R.M.2
-
21
-
-
0032533173
-
Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin-insensitive site (serine 111)
-
Heesom K.J., Avison M.B., Diggle T.A., Denton R.M. Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin-insensitive site (serine 111). Biochem. J. 336:1998;39-48
-
(1998)
Biochem. J.
, vol.336
, pp. 39-48
-
-
Heesom, K.J.1
Avison, M.B.2
Diggle, T.A.3
Denton, R.M.4
-
22
-
-
0032508493
-
Phosphorylation of the translational regulator, PHAS-I, by protein kinase CK2
-
Fadden P., Haystead T.A.J., Lawrence J.C. Jr. Phosphorylation of the translational regulator, PHAS-I, by protein kinase CK2. FEBS Lett. 435:1998;105-109
-
(1998)
FEBS Lett.
, vol.435
, pp. 105-109
-
-
Fadden, P.1
Haystead, T.A.J.2
Lawrence Jr., J.C.3
-
23
-
-
0033621392
-
Substrate specificity and identification of putative substrates of ATM kinase family members
-
Kim S., Lim D., Canman C.E., Kastan M.B. Substrate specificity and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274:1999;37538-37543
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37538-37543
-
-
Kim, S.1
Lim, D.2
Canman, C.E.3
Kastan, M.B.4
-
24
-
-
0035933889
-
Cloning of a novel phosphatidylinositol kinase-related kinase. Characterization of the human SMG-1 RNA surveillance protein
-
Denning G., Jamieson L., Maquat L.E., Thompson E.A., Fields A.P. Cloning of a novel phosphatidylinositol kinase-related kinase. Characterization of the human SMG-1 RNA surveillance protein. J. Biol. Chem. 276:2001;22709-22714
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22709-22714
-
-
Denning, G.1
Jamieson, L.2
Maquat, L.E.3
Thompson, E.A.4
Fields, A.P.5
-
25
-
-
0032189483
-
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
-
Sarkaria J.N., Tibbetts R.S., Busby E.C., Kennedy A.P., Hill D.E., Abraham R.T. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. Cancer Res. 58:1998;4375-4382
-
(1998)
Cancer Res.
, vol.58
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Tibbetts, R.S.2
Busby, E.C.3
Kennedy, A.P.4
Hill, D.E.5
Abraham, R.T.6
-
26
-
-
0027309278
-
Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit
-
Carpenter C.L., Auger K.R., Chanudhuri M., Yoakim M., Schaffhausen B., Shoelson S., Cantley L.C. Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit. J. Biol. Chem. 268:1993;9478-9483
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 9478-9483
-
-
Carpenter, C.L.1
Auger, K.R.2
Chanudhuri, M.3
Yoakim, M.4
Schaffhausen, B.5
Shoelson, S.6
Cantley, L.C.7
-
27
-
-
0032509406
-
Binding of a diphosphotyrosine-containing peptide that mimics activated platelet-derived growth factor receptor β induces oligomerization of phosphatidylinositol 3-kinase
-
Layton M.J., Harpur A.G., Panayotou G., Bastiaens P.I.H., Waterfield M.D. Binding of a diphosphotyrosine-containing peptide that mimics activated platelet-derived growth factor receptor β induces oligomerization of phosphatidylinositol 3-kinase. J. Biol. Chem. 273:1998;33379-33385
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33379-33385
-
-
Layton, M.J.1
Harpur, A.G.2
Panayotou, G.3
Bastiaens, P.I.H.4
Waterfield, M.D.5
-
28
-
-
0028909206
-
′-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit
-
′ -kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit J. Biol. Chem. 270:1995;3662-3666
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3662-3666
-
-
Rordorf-Nikolic, T.1
Horn, D.J.V.2
Chen, D.3
White, M.F.4
Backer, J.M.5
-
29
-
-
0032514801
-
′-kinase. Distinct roles for the N-terminal and C-terminal SH2 domains
-
′ -kinase. Distinct roles for the N-terminal and C-terminal SH2 domains J. Biol. Chem. 273:1998;30199-30203
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30199-30203
-
-
Yu, J.1
Wjasow, C.2
Backer, J.M.3
-
30
-
-
0028334738
-
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits
-
Stephens L., Smrcka A., Cooke F.T., Jackson T.R., Sternweis P.C., Hawkins P.T. A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein. βγ subunits Cell. 77:1994;83-93
-
(1994)
Cell
, vol.77
, pp. 83-93
-
-
Stephens, L.1
Smrcka, A.2
Cooke, F.T.3
Jackson, T.R.4
Sternweis, P.C.5
Hawkins, P.T.6
-
31
-
-
0029090212
-
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
-
Stoyanov B., Volinia S., Hanck T., Rubio I., Loubtchenkov M., Malek D., Stoyanova S., Vanhaesebroeck B., Dhand R., Nurnberg B., Gierschik P., Seedorf K., Hsuan J.J., Waterfield M.D., Wetzker R. Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science. 269:1995;690-693
-
(1995)
Science
, vol.269
, pp. 690-693
-
-
Stoyanov, B.1
Volinia, S.2
Hanck, T.3
Rubio, I.4
Loubtchenkov, M.5
Malek, D.6
Stoyanova, S.7
Vanhaesebroeck, B.8
Dhand, R.9
Nurnberg, B.10
Gierschik, P.11
Seedorf, K.12
Hsuan, J.J.13
Waterfield, M.D.14
Wetzker, R.15
-
32
-
-
0030869757
-
Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide
-
Kurosu H., Maehama T., Okada T., Yamamoto T., Hoshino S., Fukui Y., Ui M., Hazeki O., Katada T. Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide. J. Biol. Chem. 272:1997;24252-24256
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24252-24256
-
-
Kurosu, H.1
Maehama, T.2
Okada, T.3
Yamamoto, T.4
Hoshino, S.5
Fukui, Y.6
Ui, M.7
Hazeki, O.8
Katada, T.9
-
33
-
-
0032828890
-
Roles of non-catalytic subunits in betagamma-induced activation of class I phosphoinositide 3-kinase isoforms beta and gamma
-
Maier U., Babich A., Nurnberg B. Roles of non-catalytic subunits in betagamma-induced activation of class I phosphoinositide 3-kinase isoforms beta and gamma. J. Biol. Chem. 274:1999;29311-29317
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29311-29317
-
-
Maier, U.1
Babich, A.2
Nurnberg, B.3
-
34
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana P., Warne P.H., Dhand R., Vanhaesebroeck B., Gout I., Fry M.J., Waterfield M.D., Downward J. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature. 370:1994;527-532
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
36
-
-
0033635157
-
Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma
-
Pacold M.E., Suire S., Perisic O., Lara-Gonzalez S., Davis C.T., Walker E.H., Hawkins P.T., Stephens L., Eccleson J.F., Williams R.L. Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma. Cell. 103:2000;931-943
-
(2000)
Cell
, vol.103
, pp. 931-943
-
-
Pacold, M.E.1
Suire, S.2
Perisic, O.3
Lara-Gonzalez, S.4
Davis, C.T.5
Walker, E.H.6
Hawkins, P.T.7
Stephens, L.8
Eccleson, J.F.9
Williams, R.L.10
-
37
-
-
0037046799
-
Activation of phosphoinositide 3-kinase γ by Ras
-
Suire S., Hawkins P., Stephens L. Activation of phosphoinositide 3-kinase γ by Ras. Curr. Biol. 12:2002;1068-1075
-
(2002)
Curr. Biol.
, vol.12
, pp. 1068-1075
-
-
Suire, S.1
Hawkins, P.2
Stephens, L.3
-
38
-
-
0036490708
-
Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit
-
Chan T.O., Rodeck U., Chan A.M., Kimmelman A.C., Rittenhouse S.E., Panayotou G., Tsichlis P.N. Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit. Cancer Cell. 1:2002;181-191
-
(2002)
Cancer Cell
, vol.1
, pp. 181-191
-
-
Chan, T.O.1
Rodeck, U.2
Chan, A.M.3
Kimmelman, A.C.4
Rittenhouse, S.E.5
Panayotou, G.6
Tsichlis, P.N.7
-
39
-
-
0037695596
-
The p85 regulatory subunit controls sequential activation of phosphoinositide 3-kinase by Tyr kinases and Ras
-
Jimenez C., Hernandez C., Pimentel B., Carrera A.C. The p85 regulatory subunit controls sequential activation of phosphoinositide 3-kinase by Tyr kinases and Ras. J. Biol. Chem. 23:2002;23
-
(2002)
J. Biol. Chem.
, vol.23
, pp. 23
-
-
Jimenez, C.1
Hernandez, C.2
Pimentel, B.3
Carrera, A.C.4
-
40
-
-
1542289973
-
Direct interaction of MHC class II derived peptides with class Ia PI 3-kinase results in dose-dependent stimulatory effects
-
Foukas L.C., Panayotou G., Shepherd P.R. Direct interaction of MHC class II derived peptides with class Ia PI 3-kinase results in dose-dependent stimulatory effects. J. Biol. Chem. 279:2004;7505-7511
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7505-7511
-
-
Foukas, L.C.1
Panayotou, G.2
Shepherd, P.R.3
-
41
-
-
0023472472
-
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
-
Schagger H., von Jagow G. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100. kDa Anal. Biochem. 166:1987;368-379
-
(1987)
Anal. Biochem.
, vol.166
, pp. 368-379
-
-
Schagger, H.1
Von Jagow, G.2
-
42
-
-
0028197377
-
A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3-kinase
-
Woscholski R., Kodaki T., McKinnon M., Waterfield M.D., Parker P.J. A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3-kinase. FEBS Lett. 342:1994;109-114
-
(1994)
FEBS Lett.
, vol.342
, pp. 109-114
-
-
Woscholski, R.1
Kodaki, T.2
McKinnon, M.3
Waterfield, M.D.4
Parker, P.J.5
-
43
-
-
0027936088
-
Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase
-
Haystead T.A.J., Haystead C.M.M., Hu C., Lin T.-A., Lawrence J.C. Jr. Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. J. Biol. Chem. 269:1994;23185-23191
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23185-23191
-
-
Haystead, T.A.J.1
Haystead, C.M.M.2
Hu, C.3
Lin, T.-A.4
Lawrence Jr., J.C.5
-
44
-
-
0029990003
-
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
-
Rodriguez-Viciana P., Warne P.H., Vanhaesebroeck B., Waterfield M.D., Downward J. Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation. EMBO J. 15:1996;2442-2451
-
(1996)
EMBO J.
, vol.15
, pp. 2442-2451
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Vanhaesebroeck, B.3
Waterfield, M.D.4
Downward, J.5
-
45
-
-
0032500730
-
Bifurcation of lipid and protein kinase signals of PI3Kgamma to protein kinases PKB and MAPK
-
Bondeva T., Pirola L., Bulgarelli-Leva G., Rubio I., Wetzker R., Wymann M.P. Bifurcation of lipid and protein kinase signals of PI3Kgamma to protein kinases PKB and MAPK. Science. 282:1998;293-296
-
(1998)
Science
, vol.282
, pp. 293-296
-
-
Bondeva, T.1
Pirola, L.2
Bulgarelli-Leva, G.3
Rubio, I.4
Wetzker, R.5
Wymann, M.P.6
-
46
-
-
0035877577
-
Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase α (PI3Kα)
-
Pirola L., Zvelebil M.J., Bulgarelli-Leva G., Obberghen E.V., Waterfield M.D., Wymann M.P. Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase α (PI3Kα). J. Biol. Chem. 276:2001;21544-21554
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21544-21554
-
-
Pirola, L.1
Zvelebil, M.J.2
Bulgarelli-Leva, G.3
Obberghen, E.V.4
Waterfield, M.D.5
Wymann, M.P.6
-
47
-
-
0030013407
-
Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat epididymal fat-cells
-
Diggle T.A., Moule S.K., Avison M.B., Flynn A., Foulstone E.J., Proud C.G., Denton R.M. Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat epididymal fat-cells. Biochem. J. 316:1996;447-453
-
(1996)
Biochem. J.
, vol.316
, pp. 447-453
-
-
Diggle, T.A.1
Moule, S.K.2
Avison, M.B.3
Flynn, A.4
Foulstone, E.J.5
Proud, C.G.6
Denton, R.M.7
-
48
-
-
0029095931
-
Control of PHAS-I by insulin in 3T3-L1 adipocytes
-
Lin T.-A., Kong X., Saltiel A.R., Blackshear P.J., Lawrence J.C. Jr. Control of PHAS-I by insulin in 3T3-L1 adipocytes. J. Biol. Chem. 270:1995;18531-18538
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18531-18538
-
-
Lin, T.-A.1
Kong, X.2
Saltiel, A.R.3
Blackshear, P.J.4
Lawrence Jr., J.C.5
-
49
-
-
0024271996
-
Novel phosphorylation of c-ras p21 by protein kinases
-
Saikumar P., Ulsh L.S., Clanton D.J., Huang K.-P., Shih T.Y. Novel phosphorylation of c-ras p21 by protein kinases. Oncogene Res. 3:1988;213-222
-
(1988)
Oncogene Res.
, vol.3
, pp. 213-222
-
-
Saikumar, P.1
Ulsh, L.S.2
Clanton, D.J.3
Huang, K.-P.4
Shih, T.Y.5
-
50
-
-
0037016758
-
The linker domain of the Ha-Ras hypervariable region regulates interactions with exchange factors, Raf-1 and phosphoinositide 3-kinase
-
Jaumot M., Yan J., Clyde-Smith J., Sluimer J., Hancock J.F. The linker domain of the Ha-Ras hypervariable region regulates interactions with exchange factors, Raf-1 and phosphoinositide 3-kinase. J. Biol. Chem. 277:2002;272-278
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 272-278
-
-
Jaumot, M.1
Yan, J.2
Clyde-Smith, J.3
Sluimer, J.4
Hancock, J.F.5
|