ADAM33 polymorphisms and phenotype associations in childhood asthma

Journal of Allergy and Clinical Immunology

Volumn 113, Issue 6, 2004, Pages 1071-1078

  Raby, Benjamin A ^a,b,c   Silverman, Edwin K ^a,c   Kwiatkowski, David J ^a,c   Lange, Christoph ^d   Lazarus, Ross ^a   Weiss, Scott T ^a,c,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

A disintegrin and metalloproteinase; ADAM; ADAM33; association studies; Asthma; CAMP; Childhood Asthma Management Program; genetics; haplotype; LD; Linkage disequilibrium; metalloproteinases; Single nucleotide polymorphism; SNP; UK; United Kingdom

Indexed keywords

DISINTEGRIN; METALLOPROTEINASE;

ARTICLE; ASTHMA; CHILD; CHILDHOOD DISEASE; COHORT ANALYSIS; CONTROLLED STUDY; FAMILY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENOTYPE; HAPLOTYPE; HUMAN; MALE; MASS SPECTROMETRY; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADAM PROTEINS; ASTHMA; CHILD; DOUBLE-BLIND METHOD; FEMALE; FORCED EXPIRATORY VOLUME; GENE FREQUENCY; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; METALLOENDOPEPTIDASES; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 3042795020     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2004.03.035     Document Type: Article

References (31)

1. Mannino D.M., Homa D.M., Pertowski C.A., Ashizawa A., Nixon L.L., Johnson C.A., et al. Surveillance for asthma - United States, 1960-1995. Morb Mortal Wkly Rep CDC Surveill Summ. 47:1998;1-27
2. Lander E.S., Schork N.J. Genetic dissection of complex traits. Science. 265:1994;2037-2048
3. Wjst M., Immervoll T. An Internet linkage and mutation database for the complex phenotype asthma. Bioinformatics. 14:1998;827-828
4. Van Eerdewegh P., Little R.D., Dupuis J., Del Mastro R.G., Falls K., Simon J., et al. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature. 418:2002;426-430
5. Drazen J.M., Weiss S.T. Genetics: inherit the wheeze. Nature. 418:2002;383-384
6. Shapiro S.D., Owen C.A. ADAM-33 surfaces as an asthma gene. N Engl J Med. 347:2002;936-938
7. Howard T.D., Postma D.S., Jongepier H., Moore W.C., Koppelman G.H., Zheng S.L., et al. Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations. J Allergy Clin Immunol. 112:2003;717-722
8. Lind D.L., Choudhry S., Ung N., Ziv E., Avila P.C., Salari K., et al. ADAM33 is not associated with asthma in Puerto Rican or Mexican populations. Am J Respir Crit Care Med. 168:2003;1312-1316
9. Childhood Asthma Management Program Research Group. The Childhood Asthma Management Program (CAMP): design, rationale, and methods. Control Clin Trials. 20:1999;91-120
10. The Childhood Asthma Management Program Research Group. Long-term effects of budesonide or nedocromil in children with asthma. N Engl J Med. 343:2000;1054-1063
11. Rabinowitz D., Laird N. A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Hum Hered. 50:2000;211-223
12. Laird N.M., Horvath S., Xu X. Implementing a unified approach to family-based tests of association. Genet Epidemiol. 19:2000;S36-S42
13. Haldane J.B.S. An exact test for randomness of mating. J Genet. 52:1954;631-635
14. Hill W.G. Estimation of linkage disequilibrium in randomly mating populations. Heredity. 33:1974;229-239
15. Hill W.G., Robertson A. Linkage disequilibrium in finite populations. Theor Appl Genet. 38:1968;226-231
16. Stephens M., Smith N.J., Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet. 68:2001;978-989
17. Stephens M., Li M. Phase. 2001;Department of Statistics, University of Washington, Seattle
18. Zhang K., Jin L. HaploBlockFinder: haplotype block analyses. Bioinformatics. 19:2003;1300-1301
19. Lange C., Laird N.M. On a general class of conditional tests for family-based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations. Genet Epidemiol. 23:2002;165-180
20. Lange C., DeMeo D., Silverman E.K., Weiss S.T., Laird N.M. Using the noninformative families in family-based association tests: a powerful new testing strategy. Am J Hum Genet. 73:2003;801-811
21. Clayton D. A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission. Am J Hum Genet. 65:1999;1170-1177
22. Umland S.P., Garlisi C.G., Shah H., Wan Y., Zou J., Devito K.E., et al. Human ADAM33 messenger RNA expression profile and post-transcriptional regulation. Am J Respir Cell Mol Biol. 29:2003;571-582
23. De Sanctis G.T., Merchant M., Beier D.R., Dredge R.D., Grobholz J.K., Martin T.R., et al. Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nat Genet. 11:1995;150-154
24. Holgate S.T., Davies D.E., Murphy G., Powell R.M., Holloway J.W. ADAM 33: just another asthma gene or a breakthrough in understanding the origins of bronchial hyperresponsiveness? Thorax. 58:2003;466-469
25. Cookson W. A new gene for asthma: would you ADAM and Eve it? Trends Genet. 19:2003;169-172
26. Lander E., Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet. 11:1995;241-247
27. Knowler W.C., Williams R.C., Pettitt D.J., Steinberg A.G. Gm3;5, 13, 14 and type 2 diabetes mellitus: an association in American Indians with genetic admixture. Am J Hum Genet. 43:1988;520-526
28. Pritchard J.K., Donnelly P. Case-control studies of association in structured or admixed populations. Theor Popul Biol. 60:2001;227-237
29. Lohmueller K.E., Pearce C.L., Pike M., Lander E.S., Hirschhorn J.N. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet. 33:2003;177-182
30. Ioannidis J.P., Ntzani E.E., Trikalinos T.A., Contopoulos-Ioannidis D.G. Replication validity of genetic association studies. Nat Genet. 29:2001;306-309
31. Ober C., Tsalenko A., Parry R., Cox N.J. A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. Am J Hum Genet. 67:2000;1154-1162