Effect of IL-1β on CRE-dependent gene expression in human airway smooth muscle cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 283, Issue 6 27-6, 2002, Pages

  Lahiri, Thomas ^a   Moore, Paul E ^a   Baraldo, Simonetta ^a   Whitehead, Timothy R ^a   McKenna, Matthew D ^a   Panettieri Jr , Reynold A ^b   Shore, Stephanie A ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

CAMP response element binding; Cyclooxygenase 2; Dexamethasone; Luciferase; Mitogen activated protein kinase; Tumor necrosis factor

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUCLADESINE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; DEXAMETHASONE; INDOMETACIN; INTERLEUKIN 1BETA; ISOPRENALINE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROSTAGLANDIN SYNTHASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; CYCLIC AMP; INTERLEUKIN 1; INTERLEUKIN 6;

AIRWAY; ARTICLE; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; DNA BINDING; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPORTER GENE; SMOOTH MUSCLE FIBER; SMOOTH MUSCLE RELAXATION; CELL CULTURE; CYTOLOGY; DNA RESPONSIVE ELEMENT; DRUG EFFECT; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROMOTER REGION; SMOOTH MUSCLE; TRACHEA;

ADRENERGIC BETA-AGONISTS; BUCLADESINE; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE EXPRESSION; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; ISOPROTERENOL; MUSCLE, SMOOTH; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS; TRACHEA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036884990     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00231.2001     Document Type: Article

References (35)

1. Ammit AJ, Hoffman RK, Amrani Y, Lazaar AL, Hay DW, Torphy TJ, Penn RB, and Panettieri RA Jr. Tumor necrosis factor-α-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: Modulation by cyclic adenosine monophosphate. Am J Respir Cell Mol Biol 23: 794-802, 2000.
2. Ammit AJ, Lazaar AL, Irani C, O'Neill GM, Gordon ND, Amrani Y, Penn RB, and Panettieri RA Jr. Tumor necrosis factor-α-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: Modulation by glucocorticoids and β-agonists. Am J Respir Cell Mol Biol 26: 465-474, 2002.
3. Bai TR. Abnormalities in airway smooth muscle in fatal asthma. Am Rev Respir Dis 141: 552-557, 1990.
4. Barnes PJ and Pride NB. Dose-response curves to inhaled β-adrenoceptor agonists in normal and asthmatic subjects. Br J Clin Pharmacol 15: 677-682, 1983.
5. Cuenda A, Rouse J, Doza YN, Meier R, Cohen P, Gallagher TF, Young PR, and Lee JC. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 364: 229-233, 1995.
6. De Cesare D, Fimia GM, and Sassone-Corsi P. Signaling routes to CREM and CREB: Plasticity in transcriptional activation. Trends Biochem Sci 24: 281-285, 1999.
7. Eickelberg O, Pansky A, Mussmann R, Bihl M, Tamm M, Hildebrand P, Perruchoud AP, and Roth M. Transforming growth factor-β1 induces interleukin-6 expression via activating protein-1 consisting of JunD homodimers in primary human lung fibroblasts. J Biol Chem 274: 12933-12938, 1999.
8. Emala C, Black C, Curry C, Levine MA, and Hirshman CA. Impaired β-adrenergic receptor activation of adenylyl cyclase in airway smooth muscle in the basenji-greyhound dog model of airway hyperresponsiveness. Am J Respir Cell Mol Biol 8: 668-675,1993.
9. Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, and Trzaskos JM. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273: 18623-18632, 1998.
10. Gerritsen ME, Williams AJ, Neish AS, Moore S, Shi Y, and Collins T. CREB-binding protein/p300 are transcriptional coactivators of p65. Proc Natl Acad Sci USA 94: 2927-2932, 1997.
11. Hakonarson H, Herrick DJ, Serrano PG, and Grunstein MM. Mechanism of cytokine-induced modulation of β-adrenoceptor responsiveness in airway smooth muscle. J Clin Invest 97: 2593-2600, 1996.
12. 2-adrenergic receptor are involved in distinct pathways of receptor desensitization. J Biol Chem 264: 12657-12665, 1989.
13. Lalli E, Lee JS, Lamas M, Tamai K, Zazopoulos E, Nantel F, Penna L, Foulkes NS, and Sassone-Corsi P. The nuclear response to cAMP: Role of transcription factor CREM. Philos Trans R Soc Lond B Biol Sci 351: 201-209, 1996.
14. Laporte JD, Moore PE, Abraham JH, Maksym GN, Fabry B, Panettieri RA Jr, and Shore SA. Role of ERK MAP kinases in responses of cultured human airway smooth muscle cells to IL-1β. Am J Physiol Lung Cell Mol Physiol 277: L943-L951, 1999.
15. Laporte JD, Moore PE, Lahiri T, Schwartzman IN, Panettieri RA Jr, and Shore SA. p38 MAP kinase regulates IL-1β responses in cultured airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 279: L932-L941, 2000.
16. Laporte JD, Moore PE, Panettieri RA, Moeller W, Heyder J, and Shore SA. Prostanoids mediate IL-1β-induced β-adrenergic hyporesponsiveness in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 275: L491-L501, 1998.
17. 2-adrenergic receptor desensitization. Delineation with specific inhibitors. J Biol Chem 265: 3202-3211, 1990.
18. Moore PE, Lahiri T, Laporte JD, Church T, Panettieri RA Jr, and Shore SA. Synergism between TNF-α and IL-1β in airway smooth muscle cells: Implications for β-adrenergic responsiveness. J Appl Physiol 91: 1467-1474, 2001.
19. 2-adrenergic receptor in human airway smooth muscle cells (Abstract). Am J Respir Crit Care Med 163: A778, 2001.
20. Moore PE, Laporte JD, Gonzalez S, Moller W, Heyder J, Panettieri RA Jr, and Shore SA. Glucocorticoids ablate IL-1β-induced β-adrenergic hyporesponsiveness in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 277: L932-L942, 1999.
21. Panettieri RA, Murray RK, DePalo LR, Yadvish PA, and Kotlikoff MI. A human airway smooth muscle cell line that retains physiological responsiveness. Am J Physiol Cell Physiol 256: C329-C335, 1989.
22. Pang L, Holland E, and Knox AJ. Role of cyclo-oxygenase-2 induction in interleukin-1β-induced attenuation of cultured human airway smooth muscle cell cyclic AMP generation in response to isoprenaline. Br J Pharmacol 125: 1320-1328, 1998.
23. Penn RB, Parent JL, Pronin AN, Panettieri RA Jr, and Benovic JL. Pharmacological inhibition of protein kinases in intact cells: Antagonism of β-adrenergic receptor ligand binding by H-89 reveals limitations of usefulness. J Pharmacol Exp Ther 288: 428-437, 1999.
24. Potter S, Mitchell MD, Hansen WR, and Marvin KW. NF-IL6 and CRE elements principally account for both basal and interleukin-1β-induced transcriptional activity of the proximal 528 bp of the PGHS-2 promoter in amnion-derived AV3 cells: Evidence for involvement of C/EBPβ. Mol Hum Reprod 6: 771-778, 2000.
25. Premont RT, Inglese J, and Lefkowitz RJ. Protein kinases that phosphorylate activated G protein-coupled receptors. FASEB J 9: 175-182, 1995.
26. Rikitake Y, Hirata K, Kawashima S, Takeuchi S, Shimokawa Y, Kojima Y, Inoue N, and Yokoyama M. Signaling mechanism underlying COX-2 induction by lysophosphatidylcholine. Biochem Biophys Res Commun 281: 1291-1297, 2001.
27. Sassone-Corsi P. Coupling gene expression to cAMP signalling: Role of CREB and CREM. Int J Biochem Cell Biol 30: 27-38, 1998.
28. Scheid CR, Honeyman TW, and Fay FS. Mechanism of β-adrenergic relaxation of smooth muscle. Nature 277: 32-36, 1979.
29. Shaywitz AJ and Greenberg ME. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 68: 821-861, 1999.
30. Sheppard KA, Phelps KM, Williams AJ, Thanos D, Glass CK, Rosenfeld MG, Gerritsen ME, and Collins T. Nuclear integration of glucocorticoid receptor and nuclear factor-κB signaling by CREB-binding protein and steroid receptor coactivator-1. J Biol Chem 273: 29291-29294, 1998.
31. Shore SA, Laporte J, Hall IP, Hardy E, and Panettieri RA Jr. Effect of IL-1β on responses of cultured human airway smooth muscle cells to bronchodilator agonists. Am J Respir Cell Mol Biol 16: 702-712, 1997.
32. Tamai KT, Monaco L, Nantel F, Zazopoulos E, and Sassone-Corsi P. Coupling signalling pathways to transcriptional control: Nuclear factors responsive to cAMP. Recent Prog Horm Res 52: 121-139, 1997.
33. Torphy TJ. β-Adrenoceptors, cAMP and airway smooth muscle relaxation: Challenges to the dogma. Trends Pharmacol Sci 15: 370-374, 1994.
34. Whitehead TR, Moore PE, McKenna MD, Silverman ES, Panettieri RA Jr, and Shore SA. Involvement of C/EBPβ in oncostatin-M- and IL-1β-induced COX-2 expression in human airway smooth muscle (HASM) cells (Abstract). Am J Respir Crit Care Med 165: A116, 2002.
35. Wills-Karp M, Uchida Y, Lee JY, Jinot J, Hirata A, and Hirata F. Organ culture with proinflammatory cytokines reproduces impairment of the β-adrenoceptor-mediated relaxation in tracheas of a guinea pig antigen model. Am J Respir Cell Mol Biol 8: 153-159, 1993.