4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy

American Journal of Respiratory Cell and Molecular Biology

Volumn 33, Issue 2, 2005, Pages 195-202

  Zhou, Limei ^b   Goldsmith, Adam M ^b   Bentley, J Kelley ^b   Jia, Yue ^b   Rodriguez, Michael L ^b   Abe, Mark K ^b   Fingar, Diane C ^b   Hershenson, Marc B ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b NONE

Author keywords

Mammalian target of rapamycin; Phosphatidylinositol 3 kinase; Protein synthesis; Translation

Indexed keywords

INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; VIRUS LARGE T ANTIGEN; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)IMIDAZOLE; CARRIER PROTEIN; CHROMONE DERIVATIVE; EIF4EBP1 PROTEIN, HUMAN; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE P38; MORPHOLINE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN; PROTEIN KINASE; PYRIDINE DERIVATIVE; RAPAMYCIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; ASTHMA; BINDING AFFINITY; CELL CYCLE G1 PHASE; CELL GROWTH; CELL IMMORTALIZATION; CELL SIZE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MUSCLE HYPERTROPHY; NONHUMAN; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; RESPIRATORY EPITHELIUM; RETROVIRUS; RNA TRANSLATION; TEMPERATURE SENSITIVITY; BRONCHUS; CELL ENLARGEMENT; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HYPERTROPHY; METABOLISM; MUTATION; PATHOLOGY; PHOSPHORYLATION; SMOOTH MUSCLE; TEMPERATURE;

EUKARYOTA; MAMMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BRONCHI; CARRIER PROTEINS; CELL ENLARGEMENT; CELL LINE; CHROMONES; ENZYME INHIBITORS; EUKARYOTIC INITIATION FACTOR-4E; HUMANS; HYPERTROPHY; IMIDAZOLES; MORPHOLINES; MUSCLE, SMOOTH; MUTATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PYRIDINES; SIROLIMUS; TEMPERATURE; TRANSFECTION;

EID: 24344471377     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2004-0411OC     Document Type: Article

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