Activity of γ-secretase on substrates other than APP

Current Topics in Medicinal Chemistry

Volumn 8, Issue 1, 2008, Pages 9-16

  Lleó, Alberto ^a  

^a HOSPITAL CLÍNIC   (Spain)

Author keywords

secretase substrates; Alzheimer's; Amyloid ; Modulators; Notch receptor

Indexed keywords

AMYLOID PRECURSOR PROTEIN; ANTERIOR PHARYNX 1; ASPARTIC PROTEINASE; CADHERIN; CELL ADHESION MOLECULE; CENTRAL NERVOUS SYSTEM AGENTS; COLONY STIMULATING FACTOR 1; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; GAMMA SECRETASE MODULATOR; GLUTAMATE RECEPTOR 3; GROWTH HORMONE RECEPTOR; INTERLEUKIN 1 RECEPTOR TYPE I; LIGAND; LOW DENSITY LIPOPROTEIN RECEPTOR; MEMBRANE PROTEIN; NEUROTROPHIN RECEPTOR P75; NONSTEROID ANTIINFLAMMATORY AGENT; NOTCH RECEPTOR; PRESENILIN 1; PRESENILIN ENHANCER 2; PROTEASOME; SYNDECAN; SECRETASE;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; DISEASE MODEL; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE MUTATION; HUMAN; MULTIGENE FAMILY; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; TOXICITY; ANIMAL; CELL ADHESION; CHEMISTRY; DRUG ANTAGONISM; METABOLISM; PROTEIN BINDING;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELL ADHESION; HUMANS; PROTEIN BINDING; RECEPTORS, NOTCH; SUBSTRATE SPECIFICITY;

EID: 40349100486     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802608783334060     Document Type: Review

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