Presenilin attenuates receptor-mediated signaling and synaptic function

Journal of Neuroscience

Volumn 25, Issue 6, 2005, Pages 1540-1549

  Parent, Angèle T ^a   Barnes, Natalie Y ^a   Taniguchi, Yoshihito ^a,b   Thinakaran, Gopal ^a   Sisodia, Sangram S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

secretase; Alzheimer's disease; cAMP PKA pathway; Deleted in colorectal cancer; Glutamatergic synaptic transmission; Neurite outgrowth

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GAMMA SECRETASE; GLUTAMATE RECEPTOR; PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; EMBRYO; MOUSE; NERVE CELL CULTURE; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CARBAMATES; CARBAZOLES; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL MEMBRANE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIPEPTIDES; ENDOPEPTIDASES; EXCITATORY POSTSYNAPTIC POTENTIALS; FORSKOLIN; GENES, DCC; GLUTAMIC ACID; INDOLES; LIDOCAINE; MEMBRANE PROTEINS; MEMORY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURITES; NEUROBLASTOMA; NEURONS; PIPERAZINES; PRESENILIN-1; PROTEIN PROCESSING, POST-TRANSLATIONAL; PYRROLES; QUINOXALINES; RATS; RECEPTORS, CELL SURFACE; RECOMBINANT FUSION PROTEINS; SECOND MESSENGER SYSTEMS; SYNAPTIC TRANSMISSION; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

EID: 13844299709     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3850-04.2005     Document Type: Article

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