-
1
-
-
0029101491
-
-
Rogaev, E. I., Sherrington, R., Rogaeva, E. A., Levesque, G., Ikeda, M., Liang, Y., Chi, H., Lin, C., Holman, K., Tsuda, T., Mar, L., Sorbi, S., Nacmias, B., Piacentini, S., Amaducci, L., Chumakov, I., Cohen, D., Lannfelt, L., Fraser, P. E., Rommens, J. M., and St. George-Hyslop, P. H. (1995) Nature 376, 775-778
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, C.8
Holman, K.9
Tsuda, T.10
Mar, L.11
Sorbi, S.12
Nacmias, B.13
Piacentini, S.14
Amaducci, L.15
Chumakov, I.16
Cohen, D.17
Lannfelt, L.18
Fraser, P.E.19
Rommens, J.M.20
St George-Hyslop, P.H.21
more..
-
2
-
-
0029087026
-
-
Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D. M., Oshima, J., Pettingell, W. H., Yu, C. E., Jondro, P. D., Schmidt, S. D., Wang, K., Crowley, A. C., Fu, Y.-H., Guenette, S. Y., Galas, D., Nemens, E., Wijsman, E. M., Bird, T. D., Schellenberg, G. D., and Tanzi, R. E. (1995) Science 269, 973-977
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.E.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
Crowley, A.C.11
Fu, Y.-H.12
Guenette, S.Y.13
Galas, D.14
Nemens, E.15
Wijsman, E.M.16
Bird, T.D.17
Schellenberg, G.D.18
Tanzi, R.E.19
-
3
-
-
0029115555
-
-
Clark, R., Hutton, M., Fuldner, R., Froelich, S., Karran, E., Talbot, C., Crook, R., Lendon, C., Prihar, G., He, C., Korenblat, K., Martinez, A., Wragg, M., Busfield, F., Behrens, M., Myers, A., Norton, J., Morris, J., Mehta, N., Pearson, C., Lincoln, S., Baker, M., Duff, K., Zehr, C., Perez-Tur, J., Houlden, H., Ruiz, A., Ossa, J., Lopera, F., Arcos, M., Madrigal, L., Collinge, J., Humphreys, C., Ashworth, A., Sarner, S., Fox, N., Harvey, R., Kennedy, A., Rpques, P., Cline, R., Philips, C., Venter, J., Forsell, L., Axelman, K., Lilius, L., Johnston, J., Cowburn, R., Viitanen, M., Winblad, B., Kosik, K., Haltia, M., Poyhonen, M., Dickson, D., Mann, D., Neary, D., Snowden, J., Lantos, P., Lannfelt, L., Rossor, M., Roberts, G., Adams, M., Hardy, J., and Goate, A. (1995) Nature Genetics 11, 219-222
-
(1995)
Nature Genetics
, vol.11
, pp. 219-222
-
-
Clark, R.1
Hutton, M.2
Fuldner, R.3
Froelich, S.4
Karran, E.5
Talbot, C.6
Crook, R.7
Lendon, C.8
Prihar, G.9
He, C.10
Korenblat, K.11
Martinez, A.12
Wragg, M.13
Busfield, F.14
Behrens, M.15
Myers, A.16
Norton, J.17
Morris, J.18
Mehta, N.19
Pearson, C.20
Lincoln, S.21
Baker, M.22
Duff, K.23
Zehr, C.24
Perez-Tur, J.25
Houlden, H.26
Ruiz, A.27
Ossa, J.28
Lopera, F.29
Arcos, M.30
Madrigal, L.31
Collinge, J.32
Humphreys, C.33
Ashworth, A.34
Sarner, S.35
Fox, N.36
Harvey, R.37
Kennedy, A.38
Rpques, P.39
Cline, R.40
Philips, C.41
Venter, J.42
Forsell, L.43
Axelman, K.44
Lilius, L.45
Johnston, J.46
Cowburn, R.47
Viitanen, M.48
Winblad, B.49
Kosik, K.50
Haltia, M.51
Poyhonen, M.52
Dickson, D.53
Mann, D.54
Neary, D.55
Snowden, J.56
Lantos, P.57
Lannfelt, L.58
Rossor, M.59
Roberts, G.60
Adams, M.61
Hardy, J.62
Goate, A.63
more..
-
4
-
-
16044373524
-
-
Scheuner, D., Eckman, C., Jensen, M., Song, X., Citron, M., Suzuki, N., Bird, T. D., Hardy, J., Hutton, M., Kukull, W., Larson, E., Levylahad, E., Viitanen, M., Peskind, E., Poorkaj, P., Schellenberg, G., Tanzi, R., Wasco, W., Lannfelt, L., Selkoe, D., and Younkin, S. (1996) Nat. Med. 2, 864-870
-
(1996)
Nat. Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levylahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
5
-
-
16944362157
-
-
Citron, M., Westaway, D., Xia, W., Carlson, G., Diehl, T., Levesque, G., Johnson-Wood, K., Lee, M., Seubert, P., Davis, A., Kholodenko, D., Motter, R., Sherrington, R., Perry, B., Yao, H., Strome, R., Lieberburg, I., Rommens, J., Kim, S., Schenk, D., Fraser, P., St George Hyslop, P., and Selkoe, D. J. (1997) Nat. Med. 3, 67-72
-
(1997)
Nat. Med.
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St George Hyslop, P.22
Selkoe, D.J.23
more..
-
6
-
-
0027258525
-
-
Jarrett, J., Berger, E., and Lansbury, P. (1993) Biochemistry 32, 4693-4697
-
(1993)
Biochemistry
, vol.32
, pp. 4693-4697
-
-
Jarrett, J.1
Berger, E.2
Lansbury, P.3
-
8
-
-
0033597105
-
-
Murphy, M. P., Hickman, L. J., Eckman, C. B., Uljon, S. N., Wang, R., and Golde, T. E. (1999) J. Biol. Chem. 274, 11914-11923
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11914-11923
-
-
Murphy, M.P.1
Hickman, L.J.2
Eckman, C.B.3
Uljon, S.N.4
Wang, R.5
Golde, T.E.6
-
9
-
-
0025295039
-
-
Esch, F., Keim, P. S., Beattie, E. C., Blacher, R. W., Culwell, A. R., Oltersdorf, T., McClure, D., and Ward, P. J. (1990) Science 248, 1122-1124
-
(1990)
Science
, vol.248
, pp. 1122-1124
-
-
Esch, F.1
Keim, P.S.2
Beattie, E.C.3
Blacher, R.W.4
Culwell, A.R.5
Oltersdorf, T.6
McClure, D.7
Ward, P.J.8
-
10
-
-
0025373508
-
-
Sisodia, S. S., Koo, E. H., Beyreuther, K., Unterbeck, A., and Price, D. L. (1990) Science 248, 492-495
-
(1990)
Science
, vol.248
, pp. 492-495
-
-
Sisodia, S.S.1
Koo, E.H.2
Beyreuther, K.3
Unterbeck, A.4
Price, D.L.5
-
12
-
-
0026476297
-
-
Nitsch, R., Slack, B., Wurtman, R., and Growdon, J. (1992) Science 258, 304-307
-
(1992)
Science
, vol.258
, pp. 304-307
-
-
Nitsch, R.1
Slack, B.2
Wurtman, R.3
Growdon, J.4
-
13
-
-
0025296205
-
-
Buxbaum, J. D., Gandy, S. E., Ciccetti, P., Ehrlich, M. E., Czernik, A. J., Fracasso, R. P., Ramabhadran, T. V., Unterbeck, A. J., and Greengard, P. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 6003-6006
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 6003-6006
-
-
Buxbaum, J.D.1
Gandy, S.E.2
Ciccetti, P.3
Ehrlich, M.E.4
Czernik, A.J.5
Fracasso, R.P.6
Ramabhadran, T.V.7
Unterbeck, A.J.8
Greengard, P.9
-
14
-
-
0027487188
-
-
Slack, B. E., Nitsch, R. M., Livneh, E., Kunz, G. M., Jr., Breu, J., Eldar, H., and Wurtman, R. J. (1993) J. Biol. Chem. 268, 21097-21101
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21097-21101
-
-
Slack, B.E.1
Nitsch, R.M.2
Livneh, E.3
Kunz G.M., Jr.4
Breu, J.5
Eldar, H.6
Wurtman, R.J.7
-
15
-
-
0030753089
-
-
Xia, W., Zhang, J., Perez, R., Koo, E. H., and Selkoe, D. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 8208-8213
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 8208-8213
-
-
Xia, W.1
Zhang, J.2
Perez, R.3
Koo, E.H.4
Selkoe, D.J.5
-
16
-
-
0032556859
-
-
De Strooper, B., Saftig, P., Craessaerts, K., Vanderstichele, H., Guhde, G., Annaert, W., Von Figura, K., and Van Leuven, F. (1997) Nature 391, 387-390
-
(1997)
Nature
, vol.391
, pp. 387-390
-
-
De Strooper, B.1
Saftig, P.2
Craessaerts, K.3
Vanderstichele, H.4
Guhde, G.5
Annaert, W.6
Von Figura, K.7
Van Leuven, F.8
-
17
-
-
0000138540
-
-
Naruse, S., Thinakaran, G., Luo, J., Kusiak, J., Tomita, T., Iwatsubo, T., Qian, X., Ginty, D., Price, D., Borchelt, D., Wong, P., and Sisodia, S. (1998) Neuron 21, 1213-1221
-
(1998)
Neuron
, vol.21
, pp. 1213-1221
-
-
Naruse, S.1
Thinakaran, G.2
Luo, J.3
Kusiak, J.4
Tomita, T.5
Iwatsubo, T.6
Qian, X.7
Ginty, D.8
Price, D.9
Borchelt, D.10
Wong, P.11
Sisodia, S.12
-
18
-
-
0033535553
-
-
Wolfe, M., Xia, W., Ostaszewski, B., Diehl, T., Kimberly, W., and Selkoe, D. (1999) Nature 398, 513-517
-
(1999)
Nature
, vol.398
, pp. 513-517
-
-
Wolfe, M.1
Xia, W.2
Ostaszewski, B.3
Diehl, T.4
Kimberly, W.5
Selkoe, D.6
-
19
-
-
0028322017
-
-
Suzuki, N., Cheung, T., Cai, X., Odaka, A., Otvos, L., Eckman, C., Golde, T., and Younkin, S. (1994) Science 264, 1336-1340
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.2
Cai, X.3
Odaka, A.4
Otvos, L.5
Eckman, C.6
Golde, T.7
Younkin, S.8
-
20
-
-
0033576636
-
-
Berechid, B. E., Thirakaran, G., Wong, P. C., Sisodia, S. S., and Nye, J. S. (1999) Curr. Biol. 9, 1493-1496
-
(1999)
Curr. Biol.
, vol.9
, pp. 1493-1496
-
-
Berechid, B.E.1
Thirakaran, G.2
Wong, P.C.3
Sisodia, S.S.4
Nye, J.S.5
-
21
-
-
17744401440
-
-
Wong, P., Zheng, H., Chen, H., Becher, M., Sirinathsinghji, D., Trumbauer, M., Chen, H., Price, D., Van der Ploeg, L., and Sisodia, S. (1997) Nature 387, 288-292
-
(1997)
Nature
, vol.387
, pp. 288-292
-
-
Wong, P.1
Zheng, H.2
Chen, H.3
Becher, M.4
Sirinathsinghji, D.5
Trumbauer, M.6
Chen, H.7
Price, D.8
Van Der Ploeg, L.9
Sisodia, S.10
-
22
-
-
0031453010
-
-
Mills, J., Charest, D., Lam, F., Beyreuther, K., Ida, N., Pelech, S., and Reiner, P. (1997) J. Neurosci. 17, 9415-9422
-
(1997)
J. Neurosci.
, vol.17
, pp. 9415-9422
-
-
Mills, J.1
Charest, D.2
Lam, F.3
Beyreuther, K.4
Ida, N.5
Pelech, S.6
Reiner, P.7
-
23
-
-
0030723893
-
-
Slack, B. E., Breu, J., Muchnicki, L., and Wurtman, R. J. (1997) Biochem. J. 327, 245-249
-
(1997)
Biochem. J.
, vol.327
, pp. 245-249
-
-
Slack, B.E.1
Breu, J.2
Muchnicki, L.3
Wurtman, R.J.4
-
24
-
-
0031054505
-
-
Weidemann, A., Paliga, K., Durrwang, U., Czech, C., Evin, G., Masters, C. L., and Beyreuther, K. (1997) Nat. Med. 3, 328-332
-
(1997)
Nat. Med.
, vol.3
, pp. 328-332
-
-
Weidemann, A.1
Paliga, K.2
Durrwang, U.3
Czech, C.4
Evin, G.5
Masters, C.L.6
Beyreuther, K.7
-
25
-
-
0029856850
-
-
Vito, P., Wolozin, B., Ganjei, J. K., Iwasaki, K., Lacana, E., and D'Adamio, L. (1996) J. Biol. Chem. 271, 31025-31028
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31025-31028
-
-
Vito, P.1
Wolozin, B.2
Ganjei, J.K.3
Iwasaki, K.4
Lacana, E.5
D'Adamio, L.6
-
26
-
-
0030680151
-
-
Vito, P., Ghayur, T., and D'Adamio, D. (1997) J. Biol. Chem. 272, 28315-28320
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28315-28320
-
-
Vito, P.1
Ghayur, T.2
D'Adamio, D.3
-
27
-
-
10544224542
-
-
Wolozin, B., Iwasaki, K., Vito, P., Ganjei, K., Lacana, E., Sunderland, T., Zhao, B., Kusiak, J., Wasco, W., and D'Adamio, L. (1996) Science 274, 1710-1713
-
(1996)
Science
, vol.274
, pp. 1710-1713
-
-
Wolozin, B.1
Iwasaki, K.2
Vito, P.3
Ganjei, K.4
Lacana, E.5
Sunderland, T.6
Zhao, B.7
Kusiak, J.8
Wasco, W.9
D'Adamio, L.10
-
28
-
-
0030667339
-
-
Ancolio, K., Marambaud, P., Dauch, P., and Checler, F. (1997) J. Neurochem. 69, 2494-2499
-
(1997)
J. Neurochem.
, vol.69
, pp. 2494-2499
-
-
Ancolio, K.1
Marambaud, P.2
Dauch, P.3
Checler, F.4
-
29
-
-
0032564388
-
-
Xia, W., Zhang, J., Ostaszewski, B., Kimberly, W., Seubert, P., Koo, E., Shen, J., and Selkoe, D. (1998) Biochemistry 37, 16465-16471
-
(1998)
Biochemistry
, vol.37
, pp. 16465-16471
-
-
Xia, W.1
Zhang, J.2
Ostaszewski, B.3
Kimberly, W.4
Seubert, P.5
Koo, E.6
Shen, J.7
Selkoe, D.8
-
30
-
-
0032032847
-
-
Qian, S., Jiang, P., Guan, X., Singh, G., Trumbauer, M., Yu, H., Chen, H., Van der Ploeg, L., and Zheng, H. (1998) Neuron 20, 611-617
-
(1998)
Neuron
, vol.20
, pp. 611-617
-
-
Qian, S.1
Jiang, P.2
Guan, X.3
Singh, G.4
Trumbauer, M.5
Yu, H.6
Chen, H.7
Van Der Ploeg, L.8
Zheng, H.9
-
31
-
-
0029906585
-
-
Levitan, D., Doyle, T., Brousseau, D., Lee, M., Thinakaran, G., Slunt, H., Sisodia, S., and Greenwald, I. (1996) Proc. Natl. Acad. Sci. U. S. A. U. S. A. 93, 14940-14944
-
(1996)
Proc. Natl. Acad. Sci. U. S. A. U. S. A.
, vol.93
, pp. 14940-14944
-
-
Levitan, D.1
Doyle, T.2
Brousseau, D.3
Lee, M.4
Thinakaran, G.5
Slunt, H.6
Sisodia, S.7
Greenwald, I.8
-
32
-
-
0032032019
-
-
PC, W.
-
Davis, J., Naruse, S., Chen, H., Eckman, C., Younkin, S., Price, D., Borchelt, D., Sisodia, S., and PC, W. (1998) Neuron 20, 603-609
-
(1998)
Neuron
, vol.20
, pp. 603-609
-
-
Davis, J.1
Naruse, S.2
Chen, H.3
Eckman, C.4
Younkin, S.5
Price, D.6
Borchelt, D.7
Sisodia, S.8
-
33
-
-
0032516821
-
-
Tomita, T., Tokuhiro, S., Hashimoto, T., Aiba, K., Saido, T. C., Maruyama, K., and Iwatsubo, T. (1998) J. Biol. Chem. 273, 21153-21160
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21153-21160
-
-
Tomita, T.1
Tokuhiro, S.2
Hashimoto, T.3
Aiba, K.4
Saido, T.C.5
Maruyama, K.6
Iwatsubo, T.7
-
34
-
-
0029671219
-
-
Vito, P., Lacana, E., and D'Adamio, L. (1996) Science 271, 521-525
-
(1996)
Science
, vol.271
, pp. 521-525
-
-
Vito, P.1
Lacana, E.2
D'Adamio, L.3
-
35
-
-
0344301890
-
-
Walter, J., Grunberg, J., Schindzielorz, A., and Haass, C. (1998) Biochemistry 37, 5961-5967
-
(1998)
Biochemistry
, vol.37
, pp. 5961-5967
-
-
Walter, J.1
Grunberg, J.2
Schindzielorz, A.3
Haass, C.4
-
36
-
-
13144265717
-
-
Takashima, A., Murayama, M., Murayama, O., Kohno, T., Honda, T., Yasutake, K., Nihonmatsu, N., Mercken, M., Yamaguchi, H., Sugihara, S., and Wolozin, B. (1998) Proc. Natl. Acad. Sci 95, 9637-9641
-
(1998)
Proc. Natl. Acad. Sci
, vol.95
, pp. 9637-9641
-
-
Takashima, A.1
Murayama, M.2
Murayama, O.3
Kohno, T.4
Honda, T.5
Yasutake, K.6
Nihonmatsu, N.7
Mercken, M.8
Yamaguchi, H.9
Sugihara, S.10
Wolozin, B.11
-
37
-
-
0031866596
-
-
Murayama, M., Tanaka, S., Palacino, J., Murayama, O., Honda, T., Sun, X., Yasatake, K., Nihonmatsu, N., Wolozin, B., and Takashima, A. (1998) FEBS Lett. 433, 73-77
-
(1998)
FEBS Lett.
, vol.433
, pp. 73-77
-
-
Murayama, M.1
Tanaka, S.2
Palacino, J.3
Murayama, O.4
Honda, T.5
Sun, X.6
Yasatake, K.7
Nihonmatsu, N.8
Wolozin, B.9
Takashima, A.10
-
38
-
-
0032531793
-
-
BA, Y.
-
Zhang, Z., Hartmann, H., Do, V., Abramowski, D., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., van de Wetering, M., Clevers, H., Saftig, P., De Strooper, B., He, X., and BA, Y. (1998) Nature 395, 698-702
-
(1998)
Nature
, vol.395
, pp. 698-702
-
-
Zhang, Z.1
Hartmann, H.2
Do, V.3
Abramowski, D.4
Sturchler-Pierrat, C.5
Staufenbiel, M.6
Sommer, B.7
Van De Wetering, M.8
Clevers, H.9
Saftig, P.10
De Strooper, B.11
He, X.12
-
39
-
-
0028988801
-
-
Zheng, H., Jiang, M., Trumbauer, M., Sirinathsinghji, D., Hopkins, R., Smith, D., Heavens, R., Dawson, G., Boyce, S., Conner, M., Price, D., and Sisodia, S. (1995) Cell 81, 525-531
-
(1995)
Cell
, vol.81
, pp. 525-531
-
-
Zheng, H.1
Jiang, M.2
Trumbauer, M.3
Sirinathsinghji, D.4
Hopkins, R.5
Smith, D.6
Heavens, R.7
Dawson, G.8
Boyce, S.9
Conner, M.10
Price, D.11
Sisodia, S.12
-
40
-
-
0032529710
-
-
White, A., Zheng, H., Galatis, D., Maher, F., Hesse, L., Multhaup, G., Beyreuther, K., Masters, C., and Cappai, R. (1998) J. Neurosci. 18, 6207-6217
-
(1998)
J. Neurosci.
, vol.18
, pp. 6207-6217
-
-
White, A.1
Zheng, H.2
Galatis, D.3
Maher, F.4
Hesse, L.5
Multhaup, G.6
Beyreuther, K.7
Masters, C.8
Cappai, R.9
-
41
-
-
0033535504
-
-
De Strooper, B., Annaert, W., Cupers, P., Saftig, P., Craessaerts, K., Mumm, J., Schroeter, E., Schrijvers, V., Wolfe, M., Ray, W., Goate, A., and Kopan, R. (1999) Nature 398, 518-522
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.6
Schroeter, E.7
Schrijvers, V.8
Wolfe, M.9
Ray, W.10
Goate, A.11
Kopan, R.12
-
43
-
-
0033535555
-
-
Ye, Y., Lukinova, N., and Fortini, M. (1999) Nature 398, 525-530
-
(1999)
Nature
, vol.398
, pp. 525-530
-
-
Ye, Y.1
Lukinova, N.2
Fortini, M.3
-
44
-
-
0030917601
-
-
Guo, Q., Sopher, B., Furukawa, K., Pham, D., Robinson, N., Martin, G., and Mattson, M. (1997) J. Neurosci. 17, 4212-4222
-
(1997)
J. Neurosci.
, vol.17
, pp. 4212-4222
-
-
Guo, Q.1
Sopher, B.2
Furukawa, K.3
Pham, D.4
Robinson, N.5
Martin, G.6
Mattson, M.7
-
45
-
-
0031895968
-
-
Wolozin, B., Alexander, P., and Palacino, J. (1998) Neurobio. Aging 19, S23-S27
-
(1998)
Neurobio. Aging
, vol.19
-
-
Wolozin, B.1
Alexander, P.2
Palacino, J.3
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