-
1
-
-
0019905891
-
High-level induction of γ interferon with various mitogens in mice pretreated with Propionibacterium acnes
-
Okamura, H., Kawaguchi, K., Shoji, K. and Kawade, Y. High-level induction of γ interferon with various mitogens in mice pretreated with Propionibacterium acnes. Infect Immun 1982, 38(2): 440-3.
-
(1982)
Infect Immun
, vol.38
, Issue.2
, pp. 440-443
-
-
Okamura, H.1
Kawaguchi, K.2
Shoji, K.3
Kawade, Y.4
-
2
-
-
0032126111
-
The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci
-
Nolan, K.F., Greaves, D.R., Waldmann, H. et al. The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci. Genomics 1998, 51(1): 161-3.
-
(1998)
Genomics
, vol.51
, Issue.1
, pp. 161-163
-
-
Nolan, K.F.1
Greaves, D.R.2
Waldmann, H.3
-
3
-
-
0031573558
-
Regulation of IL-18 (IFN-γ-inducing factor) gene expression
-
Tone, M., Thompson, S.A., Tone, Y. et al. Regulation of IL-18 (IFN-γ-inducing factor) gene expression. J Immunol 1997, 159(12): 6156-63.
-
(1997)
J Immunol
, vol.159
, Issue.12
, pp. 6156-6163
-
-
Tone, M.1
Thompson, S.A.2
Tone, Y.3
-
4
-
-
0033514959
-
Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1 β are differentially regulated in human blood mononuclear cells and mouse spleen cells
-
Puren, A.J., Fantuzzi, G., Dinarello, C.A. Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1 β are differentially regulated in human blood mononuclear cells and mouse spleen cells. Proc Natl Acad Sci USA 1999, 96(5): 2256-61.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.5
, pp. 2256-2261
-
-
Puren, A.J.1
Fantuzzi, G.2
Dinarello, C.A.3
-
5
-
-
0034533297
-
Genomic organization and regulation of human interleukin-18 gene
-
Kalina, U., Ballas, K., Koyama, N. et al. Genomic organization and regulation of human interleukin-18 gene. Scand J Immunol 2000, 52(6): 525-30.
-
(2000)
Scand J Immunol
, vol.52
, Issue.6
, pp. 525-530
-
-
Kalina, U.1
Ballas, K.2
Koyama, N.3
-
6
-
-
0033567084
-
Roles of IFN consensus sequence binding protein and PU.1 in regulating IL-18 gene expression
-
Kim, Y.M., Kang, H.S., Paik, S.G. et al. Roles of IFN consensus sequence binding protein and PU.1 in regulating IL-18 gene expression. J Immunol 1999, 163(4): 2000-7.
-
(1999)
J Immunol
, vol.163
, Issue.4
, pp. 2000-2007
-
-
Kim, Y.M.1
Kang, H.S.2
Paik, S.G.3
-
7
-
-
1642386290
-
Regulation of human Il-18 gene expression: Interaction of PU.1 with GC-box binding protein is involved in human Il-18 expression in myeloid cells
-
Koyama, N., Hoelzer, D. and Ottmann, O.G. Regulation of human Il-18 gene expression: interaction of PU.1 with GC-box binding protein is involved in human Il-18 expression in myeloid cells. Eur J Immunol 2004, 34(3): 817-26.
-
(2004)
Eur J Immunol
, vol.34
, Issue.3
, pp. 817-826
-
-
Koyama, N.1
Hoelzer, D.2
Ottmann, O.G.3
-
8
-
-
0034665506
-
IFN-γ up-regulates IL-18 gene expression via IFN consensus sequence-binding protein and activator protein-1 elements in macrophages
-
Kim, Y.M., Im, J.Y., Han, S.H. et al. IFN-γ up-regulates IL-18 gene expression via IFN consensus sequence-binding protein and activator protein-1 elements in macrophages. J Immunol 2000, 165(6): 3198-205.
-
(2000)
J Immunol
, vol.165
, Issue.6
, pp. 3198-3205
-
-
Kim, Y.M.1
Im, J.Y.2
Han, S.H.3
-
9
-
-
13344260700
-
A newly defined interleukin-1?
-
Bazan, J.F., Timans, J.C. and Kastelein, R.A. A newly defined interleukin-1? Nature 1996, 379(6566): 591.
-
(1996)
Nature
, vol.379
, Issue.6566
, pp. 591
-
-
Bazan, J.F.1
Timans, J.C.2
Kastelein, R.A.3
-
10
-
-
15844367093
-
Cloning of the cDNA for human IFN-γ-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein
-
Ushio, S., Namba, M., Okura, T. et al. Cloning of the cDNA for human IFN-γ-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J Immunol 1996, 156(11): 4274-9.
-
(1996)
J Immunol
, vol.156
, Issue.11
, pp. 4274-4279
-
-
Ushio, S.1
Namba, M.2
Okura, T.3
-
11
-
-
0034235247
-
Interleukin 18: A pleiotrope participant in chronic inflammation
-
McInnes, I.B., Gracie, J.A., Leung, B.P. et al. Interleukin 18: A pleiotrope participant in chronic inflammation. Immunol Today 2000, 21(7): 312-5.
-
(2000)
Immunol Today
, vol.21
, Issue.7
, pp. 312-315
-
-
McInnes, I.B.1
Gracie, J.A.2
Leung, B.P.3
-
12
-
-
15644369352
-
Activation of interferon-γ inducing factor mediated by interleukin-1β converting enzyme
-
Gu, Y., Kuida, K., Tsutsui. H. et al. Activation of interferon-γ inducing factor mediated by interleukin-1β converting enzyme. Science 1997, 275(5297): 206-9.
-
(1997)
Science
, vol.275
, Issue.5297
, pp. 206-209
-
-
Gu, Y.1
Kuida, K.2
Tsutsui, H.3
-
13
-
-
0031004174
-
Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN-γ production
-
Ghayur, T, Banerjee, S., Hugunin, M. et al. Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN-γ production. Nature 1997, 386(6625): 619-23.
-
(1997)
Nature
, vol.386
, Issue.6625
, pp. 619-623
-
-
Ghayur, T.1
Banerjee, S.2
Hugunin, M.3
-
14
-
-
0035575705
-
Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells
-
Sugawara, S., Uehara, A., Nochi, T. et al. Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells. J Immunol 2001, 167(11): 6568-75.
-
(2001)
J Immunol
, vol.167
, Issue.11
, pp. 6568-6575
-
-
Sugawara, S.1
Uehara, A.2
Nochi, T.3
-
15
-
-
2542547288
-
Interleukin-18 as a potential target in inflammatory arthritis
-
Gracie, J.A. Interleukin-18 as a potential target in inflammatory arthritis. Clin Exp Immunol 2004, 136(3): 402-4.
-
(2004)
Clin Exp Immunol
, vol.136
, Issue.3
, pp. 402-404
-
-
Gracie, J.A.1
-
16
-
-
0242407130
-
The structure and binding mode of interleukin-18
-
Kato, Z., Jee, J., Shikano, H. et al. The structure and binding mode of interleukin-18. Nat Struct Biol 2003, 10(11 ): 966-71.
-
(2003)
Nat Struct Biol
, vol.10
, Issue.11
, pp. 966-971
-
-
Kato, Z.1
Jee, J.2
Shikano, H.3
-
17
-
-
0037310025
-
Interleukin-18
-
Gracie, J.A., Robertson, S.E. and McInnes, I.B. Interleukin-18. J Leukoc Biol 2003, 73(2): 213-24.
-
(2003)
J Leukoc Biol
, vol.73
, Issue.2
, pp. 213-224
-
-
Gracie, J.A.1
Robertson, S.E.2
McInnes, I.B.3
-
18
-
-
17844386876
-
Accessory protein-like is essential for IL-18-medialed signaling
-
Cheung, H., Chen, N.J., Cao, Z. et al. Accessory protein-like is essential for IL-18-medialed signaling. J Immunol 2005, 174(9): 5351-7.
-
(2005)
J Immunol
, vol.174
, Issue.9
, pp. 5351-5357
-
-
Cheung, H.1
Chen, N.J.2
Cao, Z.3
-
19
-
-
0032491599
-
Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling
-
Born, T.L., Thomassen, E., Bird, T.A. and Sims, J.E. Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling. J Biol Chem 1998, 273(45): 29445-50.
-
(1998)
J Biol Chem
, vol.273
, Issue.45
, pp. 29445-29450
-
-
Born, T.L.1
Thomassen, E.2
Bird, T.A.3
Sims, J.E.4
-
20
-
-
0030851728
-
Purification and characterization of the human interleukin-18 receptor
-
Torigoe, K., Ushio, S., Okura, T. et al. Purification and characterization of the human interleukin-18 receptor. J Biol Chem 1997, 272(41): 25737-12.
-
(1997)
J Biol Chem
, vol.272
, Issue.41
, pp. 25737-25812
-
-
Torigoe, K.1
Ushio, S.2
Okura, T.3
-
21
-
-
0037148510
-
Expression of interleukin (IL)-18 and functional IL-18 receptors on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for atherogenics
-
Gerdes, N., Sukhova, G.K., Libby, P. et al. Expression of interleukin (IL)-18 and functional IL-18 receptors on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for atherogenics. J Exp Med 2002, 195(2): 245-57.
-
(2002)
J Exp Med
, vol.195
, Issue.2
, pp. 245-257
-
-
Gerdes, N.1
Sukhova, G.K.2
Libby, P.3
-
22
-
-
0035059368
-
Interleukin-18 regulates both Th1 and Th2 responses
-
Nakanishi, K., Yoshimoto, T., Tsutsi, H. and Okamura, H. Interleukin-18 regulates both Th1 and Th2 responses. Annu Rev Immunol 2001, 19:423-74.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 423-474
-
-
Nakanishi, K.1
Yoshimoto, T.2
Tsutsi, H.3
Okamura, H.4
-
23
-
-
0035451438
-
A role for IL-18 in neutrophil activation
-
Leung, B.P., Culshaw, S., Gracie, J.A. et al. A role for IL-18 in neutrophil activation. J Immunol 2001, 167(5): 2879-86.
-
(2001)
J Immunol
, vol.167
, Issue.5
, pp. 2879-2886
-
-
Leung, B.P.1
Culshaw, S.2
Gracie, J.A.3
-
24
-
-
9644266698
-
Induction of allergic inflammation by interleukin-18 in experimental animal models
-
Tsutsui, H., Yoshimoto, T., Hayashi, N., Mizutani, H. and Nakanishi, K. Induction of allergic inflammation by interleukin-18 in experimental animal models. Immunol Rev 2004, 202: 115-38.
-
(2004)
Immunol Rev
, vol.202
, pp. 115-138
-
-
Tsutsui, H.1
Yoshimoto, T.2
Hayashi, N.3
Mizutani, H.4
Nakanishi, K.5
-
25
-
-
0242516124
-
+ T cells in the induction of immunoglobulin E antibodies in response to interleukin-18 treatment of mice
-
+ T cells in the induction of immunoglobulin E antibodies in response to interleukin-18 treatment of mice. J Exp Med 2003, 197(8): 997-1005.
-
(2003)
J Exp Med
, vol.197
, Issue.8
, pp. 997-1005
-
-
Yoshimoto, T.1
Min, B.2
Sugimoto, T.3
-
26
-
-
0242407130
-
The structure and binding mode of interleukin 18
-
Kato, Z., Jee, J., Shikano, H. et al. The structure and binding mode of interleukin 18. Nat Struct Biol 2003, 10(11): 966-71.
-
(2003)
Nat Struct Biol
, vol.10
, Issue.11
, pp. 966-971
-
-
Kato, Z.1
Jee, J.2
Shikano, H.3
-
27
-
-
0032127279
-
Targeted disruption of the MyD88 gene results in loss of IL-1 and IL-18 mediated function
-
Adachi, O., Kawai, T., Takeda, K. et al. Targeted disruption of the MyD88 gene results in loss of IL-1 and IL-18 mediated function. Immunity 1998, 9(1): 143-50.
-
(1998)
Immunity
, vol.9
, Issue.1
, pp. 143-150
-
-
Adachi, O.1
Kawai, T.2
Takeda, K.3
-
28
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche, H., Henzel, W.J., Shilinglaw, W., Li, S. and Cao, Z. MyD88: An adapter that recruits IRAK to the IL-1 receptor complex. Immunity 1997, 7(6): 837-47.
-
(1997)
Immunity
, vol.7
, Issue.6
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shilinglaw, W.3
Li, S.4
Cao, Z.5
-
29
-
-
0033526110
-
Defective interleukin (IL)-18 mediated natural killer and T helper cell type 1 responses in IL-1 receptor associated kinase (IRAK)-deficient mice
-
Kanakaraj, P., Ngo, K., Wu, Y. et al. Defective interleukin (IL)-18 mediated natural killer and T helper cell type 1 responses in IL-1 receptor associated kinase (IRAK)-deficient mice. J Exp Med 1999, 189(7): 1129-38.
-
(1999)
J Exp Med
, vol.189
, Issue.7
, pp. 1129-1138
-
-
Kanakaraj, P.1
Ngo, K.2
Wu, Y.3
-
30
-
-
0032489224
-
Interleukin-18 activates the IRAK-TRAF6 pathway in mouse EL-4 cells
-
Kojima, H., Takeuchi, H., Ohta, T. et al. Interleukin-18 activates the IRAK-TRAF6 pathway in mouse EL-4 cells. Biochem Biophya Res Commun 1998, 244(1): 183-6.
-
(1998)
Biochem Biophya Res Commun
, vol.244
, Issue.1
, pp. 183-186
-
-
Kojima, H.1
Takeuchi, H.2
Ohta, T.3
-
31
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao, Z., Xiong, J., Takeuchi, M., Kurama, T. and Goeddel, D.V. TRAF6 is a signal transducer for interleukin-1. Nature 1996, 383(6599): 443-6.
-
(1996)
Nature
, vol.383
, Issue.6599
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
32
-
-
0031578229
-
Interleukin-18 activates NF-κB in murine T helper type 1 cells
-
Matsumoto, S., Tsuji-Takayama, K., Aizawa, Y. et al. Interleukin-18 activates NF-κB in murine T helper type 1 cells. Biochem Viophys Res Commun 1997, 234(2): 454-57.
-
(1997)
Biochem Viophys Res Commun
, vol.234
, Issue.2
, pp. 454-457
-
-
Matsumoto, S.1
Tsuji-Takayama, K.2
Aizawa, Y.3
-
33
-
-
0033136283
-
An essential role for NF-κB in IL-18-induced IFN-γ expression in KG-1 cells
-
Kojima Haizawa, Y. Yanai, Y. et al. An essential role for NF-κB in IL-18-induced IFN-γ expression in KG-1 cells. J Immunol 1999, 162: 5063-9.
-
(1999)
J Immunol
, vol.162
, pp. 5063-5069
-
-
Kojima Haizawa, Y.1
Yanai, Y.2
-
34
-
-
33847296039
-
Posttranslationally modified proteins as mediators of sustained intestinal inflammation
-
Andrassy, M., Igwe, J., Autschbach, F. et al. Posttranslationally modified proteins as mediators of sustained intestinal inflammation. Am J Pathol 2006, 169(4): 1223-37.
-
(2006)
Am J Pathol
, vol.169
, Issue.4
, pp. 1223-1237
-
-
Andrassy, M.1
Igwe, J.2
Autschbach, F.3
-
35
-
-
4644308152
-
Interleukin-18 bioactivity: A novel target for immunopharmagological anti-inflammatory intervention
-
Mühl, H. and Pfeilschifter, J. Interleukin-18 bioactivity: A novel target for immunopharmagological anti-inflammatory intervention. Eur J Pharmacol 2004, 500(1-3): 63-71.
-
(2004)
Eur J Pharmacol
, vol.500
, Issue.1-3
, pp. 63-71
-
-
Mühl, H.1
Pfeilschifter, J.2
-
36
-
-
0035892991
-
Expression and release of IL-18 binding protein in response to IFN-γ
-
Paulukat, J., Bosmann, M., Nold, M. et al. Expression and release of IL-18 binding protein in response to IFN-γ. J Immunol 167(12): 7038-43.
-
J Immunol
, vol.167
, Issue.12
, pp. 7038-7043
-
-
Paulukat, J.1
Bosmann, M.2
Nold, M.3
-
37
-
-
0343775741
-
lnterferon-γ mediates gene expression of interleukin-18 binding protein in non-leukocytic cells
-
Mühl, H., Kampfer, H., Bosmann, M. et al. lnterferon-γ mediates gene expression of interleukin-18 binding protein in non-leukocytic cells. Biochem Biophys Res Commun 2000, 267(3): 960-3.
-
(2000)
Biochem Biophys Res Commun
, vol.267
, Issue.3
, pp. 960-963
-
-
Mühl, H.1
Kampfer, H.2
Bosmann, M.3
-
38
-
-
0037168677
-
The promoter of IL-18 binding protein activation by an IFN-γ-induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein-β
-
Hurgin, V., Novick, D. and Rubinstein, M. The promoter of IL-18 binding protein activation by an IFN-γ-induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein-β. Proc Natl Acad Sci U S A 2002, 99(26): 16957-62.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.26
, pp. 16957-16962
-
-
Hurgin, V.1
Novick, D.2
Rubinstein, M.3
-
39
-
-
0345268692
-
Interferon-γ induces expression of interleukin-18 binding protein in fibroblast-like synoviocytes
-
Möller, B., Paulukat, J., Nold, M. et al. Interferon-γ induces expression of interleukin-18 binding protein in fibroblast-like synoviocytes. Rheumatology (Oxford) 2003, 42(3): 442-5.
-
(2003)
Rheumatology (Oxford)
, vol.42
, Issue.3
, pp. 442-445
-
-
Möller, B.1
Paulukat, J.2
Nold, M.3
-
40
-
-
0035819245
-
IL-1H, an interleukin 1-related protein that binds IL-18 receptor/IL-1Rrp
-
Pan, G., Risser, P., Mao, W. et al. IL-1H, an interleukin 1-related protein that binds IL-18 receptor/IL-1Rrp. Cytokine 2001, 13(1): 1-7.
-
(2001)
Cytokine
, vol.13
, Issue.1
, pp. 1-7
-
-
Pan, G.1
Risser, P.2
Mao, W.3
-
41
-
-
0032193770
-
IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: Synergism with IL-18 for IFN-γ production
-
Yoshimoto, T., Takeda, K., Tanaka, T. et al. IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: Synergism with IL-18 for IFN-γ production. J Immunol 1998, 161(7): 3400-7.
-
(1998)
J Immunol
, vol.161
, Issue.7
, pp. 3400-3407
-
-
Yoshimoto, T.1
Takeda, K.2
Tanaka, T.3
-
42
-
-
0028845730
-
Cloning of a new cytokine that induces IFN-γ production by T cells
-
Okamura, H., Tsutsi, H., Komatsu, T. et al. Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 1995, 378(6552): 88-91.
-
(1995)
Nature
, vol.378
, Issue.6552
, pp. 88-91
-
-
Okamura, H.1
Tsutsi, H.2
Komatsu, T.3
-
43
-
-
0032169511
-
IL-18 augments perforin-dependent cytotoxicity
-
Dao, T., Mehal, W.Z. and Cripse, I.N. IL-18 augments perforin-dependent cytotoxicity. J Immunol 1998, 161(5): 2217-22.
-
(1998)
J Immunol
, vol.161
, Issue.5
, pp. 2217-2222
-
-
Dao, T.1
Mehal, W.Z.2
Cripse, I.N.3
-
44
-
-
8944226108
-
Interferon-γ- inducing factor enhances T helper 1 cytokine production by stimulated human T cells: Synergism with interleukin-12 for interferon-γ production
-
Micallef, M.J., Ohtsuki, T., Kohno, K. et al. Interferon-γ- inducing factor enhances T helper 1 cytokine production by stimulated human T cells: Synergism with interleukin-12 for interferon-γ production. Eur J Immunol 1996, 26(7): 1647-51.
-
(1996)
Eur J Immunol
, vol.26
, Issue.7
, pp. 1647-1651
-
-
Micallef, M.J.1
Ohtsuki, T.2
Kohno, K.3
-
45
-
-
0033136326
-
IL-18 is a potent coinducer of IL-13 in NK and T cells: A new potential role for IL-18 in modulating the immune response
-
Hoshino, T., Wiltrout, R.H. and Young, H.A. IL-18 is a potent coinducer of IL-13 in NK and T cells: A new potential role for IL-18 in modulating the immune response. J Immunol 1999, 162(9): 5070-77.
-
(1999)
J Immunol
, vol.162
, Issue.9
, pp. 5070-5077
-
-
Hoshino, T.1
Wiltrout, R.H.2
Young, H.A.3
-
46
-
-
0033949150
-
In vivo administration of IL-18 can induce IgE production through Th2 cytokine induction and up-regulation of CD40 ligand (CD154) expression on CD4+ T cells
-
Hoshino, T., Yagita, H., Ortlado, J.R., Wiltrout, R.H. and Young, H.A. In vivo administration of IL-18 can induce IgE production through Th2 cytokine induction and up-regulation of CD40 ligand (CD154) expression on CD4+ T cells. Eur J Immunol 2000, 30(7): 1998-2006.
-
(2000)
Eur J Immunol
, vol.30
, Issue.7
, pp. 1998-2006
-
-
Hoshino, T.1
Yagita, H.2
Ortlado, J.R.3
Wiltrout, R.H.4
Young, H.A.5
-
47
-
-
0032526840
-
Murine macrophages secrete interferon γ upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophages activation
-
Münder, M., Mallo, M., Eichmann, K. et al. Murine macrophages secrete interferon γ upon combined stimulation with interleukin (IL)-12 and IL-18: a novel pathway of autocrine macrophages activation. J Exp Med 1998, 187(12): 2103-8.
-
(1998)
J Exp Med
, vol.187
, Issue.12
, pp. 2103-2108
-
-
Münder, M.1
Mallo, M.2
Eichmann, K.3
-
48
-
-
8544275811
-
Interleukin-18: Recent advances
-
Reddy P. Interleukin-18: Recent advances. Curr Opin Hematol 2004, 11(6): 405-10.
-
(2004)
Curr Opin Hematol
, vol.11
, Issue.6
, pp. 405-410
-
-
Reddy, P.1
-
49
-
-
0033491194
-
Interleukin-18: A novel cytokine that augments both innate and acquired immunity
-
Okamura, H., Tsutsui, H., Kashiwamura, S.I., Yoshimoto, T. and Nakanishi, K. Interleukin-18: a novel cytokine that augments both innate and acquired immunity. Adv Immunol 1998, 70: 281-312.
-
(1998)
Adv Immunol
, vol.70
, pp. 281-312
-
-
Okamura, H.1
Tsutsui, H.2
Kashiwamura, S.I.3
Yoshimoto, T.4
Nakanishi, K.5
-
50
-
-
0344193088
-
Interleukin-18 perspectives on the newest interleukin
-
Gillespie, M.T. and Horwood, N.J. Interleukin-18 perspectives on the newest interleukin. Cytokine Growth Factor Rev 1998, 9(2): 109-16.
-
(1998)
Cytokine Growth Factor Rev
, vol.9
, Issue.2
, pp. 109-116
-
-
Gillespie, M.T.1
Horwood, N.J.2
-
51
-
-
0033598818
-
IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils
-
Yoshimoto, T., Tsutsui, H., Tominaga, K. et al. IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils. Proc Natl Acad Sci U S A 1999, 96(24): 13962-66.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.24
, pp. 13962-13966
-
-
Yoshimoto, T.1
Tsutsui, H.2
Tominaga, K.3
-
52
-
-
0037322642
-
Functional interactions between dendritic cells and NK cells during viral infection
-
Andrews, D.M., Scalzo, A.A., Yokoyama, W.M. et al. Functional interactions between dendritic cells and NK cells during viral infection. Nat Immunol 2003, 4(2): 175-81.
-
(2003)
Nat Immunol
, vol.4
, Issue.2
, pp. 175-181
-
-
Andrews, D.M.1
Scalzo, A.A.2
Yokoyama, W.M.3
-
53
-
-
0038687082
-
Interleukin-18 and host defence against infection
-
Dinarello, C.A. and Fantuzzi, G. Interleukin-18 and host defence against infection. J Infect Dis 2003, 187: 370-84.
-
(2003)
J Infect Dis
, vol.187
, pp. 370-384
-
-
Dinarello, C.A.1
Fantuzzi, G.2
-
54
-
-
0033617583
-
Viral clearance without destruction of infected cells during acute HBV infection
-
Guidotti, L.G., Rochford, R. and Chung, J. Viral clearance without destruction of infected cells during acute HBV infection. Science 1999, 284(5415): 825-29.
-
(1999)
Science
, vol.284
, Issue.5415
, pp. 825-829
-
-
Guidotti, L.G.1
Rochford, R.2
Chung, J.3
-
55
-
-
0036839079
-
Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice
-
Kimura, K., Kakimi, K., Wieland, S., Guidotti, L.G. and Chisari, F.V. Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice. J Virol 2002, 76(21): 10702-7.
-
(2002)
J Virol
, vol.76
, Issue.21
, pp. 10702-10707
-
-
Kimura, K.1
Kakimi, K.2
Wieland, S.3
Guidotti, L.G.4
Chisari, F.V.5
-
56
-
-
0036644065
-
Contribution of IL-18 to Th1 response and host defense against infection by Mycobacterium tuberculosis: A comparative study with IL-12p40
-
Kinjo, Y., Kawakami, K., Uezu, K. et al. Contribution of IL-18 to Th1 response and host defense against infection by Mycobacterium tuberculosis: a comparative study with IL-12p40. J Immunol 2002, 169(1): 323-9.
-
(2002)
J Immunol
, vol.169
, Issue.1
, pp. 323-329
-
-
Kinjo, Y.1
Kawakami, K.2
Uezu, K.3
-
57
-
-
0035817396
-
A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon γ production
-
Neighbors, M., Xu, X., Barrat, F. et al. A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon γ production. J Exp Med 2001, 194(3): 343-54.
-
(2001)
J Exp Med
, vol.194
, Issue.3
, pp. 343-354
-
-
Neighbors, M.1
Xu, X.2
Barrat, F.3
-
58
-
-
0034662234
-
IL-18 contributes to host resistance against infection with Cryptococcus neoformans in mice with defective IL-12 synthesis through induction of IFN-γ production by NK cells
-
Kawakami, K., Koguchi, Y., Qureshi, M.H. et al. IL-18 contributes to host resistance against infection with Cryptococcus neoformans in mice with defective IL-12 synthesis through induction of IFN-γ production by NK cells. J Immunol 2000; 165(2): 941-7.
-
(2000)
J Immunol
, vol.165
, Issue.2
, pp. 941-947
-
-
Kawakami, K.1
Koguchi, Y.2
Qureshi, M.H.3
-
59
-
-
0034099407
-
Potentiality of interleukin-18 as a useful reagent for treatment and prevention of Leishmania major infection
-
Ohkusu, K., Yoshimoto, T., Takeda, K. et al. Potentiality of interleukin-18 as a useful reagent for treatment and prevention of Leishmania major infection. Infect Immunol 2000, 68: 2449-56.
-
(2000)
Infect Immunol
, vol.68
, pp. 2449-2456
-
-
Ohkusu, K.1
Yoshimoto, T.2
Takeda, K.3
-
60
-
-
0036570015
-
The role of IL-18 in blood-stage immunity against murine malaria Plasmodium yoelii 265 and Plasmodium berghei ANKA
-
Singh, R.P., Kashiwamura, S., Rao, P. et al. The role of IL-18 in blood-stage immunity against murine malaria Plasmodium yoelii 265 and Plasmodium berghei ANKA. J Immunol 2002, 168(9): 4674-81.
-
(2002)
J Immunol
, vol.168
, Issue.9
, pp. 4674-4681
-
-
Singh, R.P.1
Kashiwamura, S.2
Rao, P.3
-
61
-
-
0142218530
-
Role of interleukin 18 in rheumatoid arthritis
-
Liew, F.Y, Wei. X.Q. and McIness, L.B. Role of interleukin 18 in rheumatoid arthritis. Ann Rheum Dis 2003, 62(Suppl. II): ii48-ii50.
-
(2003)
Ann Rheum Dis
, vol.62
, Issue.SUPPL. II
-
-
Liew, F.Y.1
Wei, X.Q.2
McIness, L.B.3
-
62
-
-
1642525667
-
The essential involvement of cross-talk between IFN-γ and TGF-β in the skin wound-gealing process
-
Ishida, Y., Kondo, T., Takayasu, T. et al. The essential involvement of cross-talk between IFN-γ and TGF-β in the skin wound-gealing process. J Immunol 2004. 172(3): 1848-55.
-
(2004)
J Immunol
, vol.172
, Issue.3
, pp. 1848-1855
-
-
Ishida, Y.1
Kondo, T.2
Takayasu, T.3
-
63
-
-
0032005857
-
Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor
-
Horwood, N.J., Udagawa, N., Elliot, J. et al. Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor. J Clin Invest 1998, 101(3): 595-603.
-
(1998)
J Clin Invest
, vol.101
, Issue.3
, pp. 595-603
-
-
Horwood, N.J.1
Udagawa, N.2
Elliot, J.3
-
64
-
-
34447123133
-
Interleukin-18 as a mediator of systemic juvenile idiopathic arthritis
-
Jelusic, M., Lukic, I.K., Tambic-Bukovac, L. et al. Interleukin-18 as a mediator of systemic juvenile idiopathic arthritis. Clin Rheum 2007, 26(8): 1332-4.
-
(2007)
Clin Rheum
, vol.26
, Issue.8
, pp. 1332-1334
-
-
Jelusic, M.1
Lukic, I.K.2
Tambic-Bukovac, L.3
-
65
-
-
0036746084
-
-
Maeno, N., Takei, S., Nomura, Y. et al. Highly elevated serum levels of interleukin-18 in systemic juvenile idiopathic arthritis but not in other juvenile idiopathic arthritis subtypes or in Kawasaki disease: Comment on the article by Kawashima et al. Arthritis Rheum 2002, 46(9): 2539-41; author reply 2541-2.
-
Maeno, N., Takei, S., Nomura, Y. et al. Highly elevated serum levels of interleukin-18 in systemic juvenile idiopathic arthritis but not in other juvenile idiopathic arthritis subtypes or in Kawasaki disease: Comment on the article by Kawashima et al. Arthritis Rheum 2002, 46(9): 2539-41; author reply 2541-2.
-
-
-
-
66
-
-
0033786599
-
Elevation of plasma interleukin-18 concetralion id correlated with disease activity in systemic lupus erythematosus
-
Wong, C.K., Li, E.K., Ho, C.Y. and Lam, C.W. Elevation of plasma interleukin-18 concetralion id correlated with disease activity in systemic lupus erythematosus. Rheumatology (Oxf.) 2000, 39(10): 1078-81.
-
(2000)
Rheumatology (Oxf.)
, vol.39
, Issue.10
, pp. 1078-1081
-
-
Wong, C.K.1
Li, E.K.2
Ho, C.Y.3
Lam, C.W.4
-
67
-
-
0037259311
-
Serum levels of interleukin-18 and s-ICAM-1 in patients affected by psoriasis: Preliminary considerations
-
Gangemi, S., Merendino, R.A., Guarneri, F. et al. Serum levels of interleukin-18 and s-ICAM-1 in patients affected by psoriasis: Preliminary considerations. J Eur Acad Dermatol Venerol 2003, 17: 42-6.
-
(2003)
J Eur Acad Dermatol Venerol
, vol.17
, pp. 42-46
-
-
Gangemi, S.1
Merendino, R.A.2
Guarneri, F.3
-
68
-
-
27644565806
-
Seum levels of TNF-α, IFN-γ, IL-6, IL-S, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity
-
Arican, O., Aral, M., Sasmaz, S. and Ciragil, P. Seum levels of TNF-α, IFN-γ, IL-6, IL-S, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. Mediators Inflamm 2005, 2005(5): 273-79.
-
(2005)
Mediators Inflamm
, vol.2005
, Issue.5
, pp. 273-279
-
-
Arican, O.1
Aral, M.2
Sasmaz, S.3
Ciragil, P.4
-
69
-
-
0038011833
-
Evolving concepts of rheumatoid arthritis
-
Firestein, G.S. Evolving concepts of rheumatoid arthritis. Nature 2003. 423(6937): 356-61.
-
(2003)
Nature
, vol.423
, Issue.6937
, pp. 356-361
-
-
Firestein, G.S.1
-
70
-
-
1942531962
-
An update on the cytokine network in rheumatoid arthritis
-
Miossec, P. An update on the cytokine network in rheumatoid arthritis. Curr Opin Rheumatol 2004, 16(3): 218-22.
-
(2004)
Curr Opin Rheumatol
, vol.16
, Issue.3
, pp. 218-222
-
-
Miossec, P.1
-
71
-
-
0032743708
-
A proinflammatory role of IL-18 in rheumatoid arthritis
-
Gracie, J.A., Forscy, R.J., Chan, W.L. et al. A proinflammatory role of IL-18 in rheumatoid arthritis. J Clin Invest 1999. 104(10): 1393-401.
-
(1999)
J Clin Invest
, vol.104
, Issue.10
, pp. 1393-1401
-
-
Gracie, J.A.1
Forscy, R.J.2
Chan, W.L.3
-
72
-
-
0034909059
-
Mature form of interleukin 18 is expressed in rheumatoid arthritis synovial tissue and contributes to interferon-γ production by synovial T cells
-
Tanaka, M., Harigai, M., Kawaguchi, Y. et al. Mature form of interleukin 18 is expressed in rheumatoid arthritis synovial tissue and contributes to interferon-γ production by synovial T cells. J Rheumatol 2001, 28(8): 1779-87.
-
(2001)
J Rheumatol
, vol.28
, Issue.8
, pp. 1779-1787
-
-
Tanaka, M.1
Harigai, M.2
Kawaguchi, Y.3
-
73
-
-
0035173776
-
Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18
-
Wei, X.Q., Leung, B.P., Arthur, H.M.. McInnes, I.B. and Liew, F. Y. Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. J Immunol 2001, 166(1): 517-21.
-
(2001)
J Immunol
, vol.166
, Issue.1
, pp. 517-521
-
-
Wei, X.Q.1
Leung, B.P.2
Arthur, H.M.3
McInnes, I.B.4
Liew, F.Y.5
-
74
-
-
0035080102
-
Levels of interleukin-18 and its binding inhibitors in the blood circulation of patients with adult-onset Still's disease
-
Kawashima, M., Yamamura, M., Taniai. M. et al. Levels of interleukin-18 and its binding inhibitors in the blood circulation of patients with adult-onset Still's disease. Arthritis Rheum 2001, 44(3): 550-60.
-
(2001)
Arthritis Rheum
, vol.44
, Issue.3
, pp. 550-560
-
-
Kawashima, M.1
Yamamura, M.2
Taniai, M.3
-
75
-
-
4644225570
-
Epidemiology of inflammatory bowel diseases
-
Sartor, R.B, Sandborn, W.J, Eds, Elsevier: London
-
Sandler, R.S. and Loftus, E.V. Jr. Epidemiology of inflammatory bowel diseases. In Sartor, R.B., Sandborn, W.J. (Eds.). Kirsner's Inflammatory Bowel Diseases. Elsevier: London 2004, 245-62.
-
(2004)
Kirsner's Inflammatory Bowel Diseases
, pp. 245-262
-
-
Sandler, R.S.1
Loftus Jr., E.V.2
-
76
-
-
0033152023
-
IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn' 2 disease: Expression and localization in intestinal mucosal cells
-
Pizarro, T.T., Michie, M.H., Bentz, M. et al. IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn' 2 disease: Expression and localization in intestinal mucosal cells. J Immunol 1999, 162(11): 6829-35.
-
(1999)
J Immunol
, vol.162
, Issue.11
, pp. 6829-6835
-
-
Pizarro, T.T.1
Michie, M.H.2
Bentz, M.3
-
77
-
-
0033168120
-
Bioactive IL-18 expression is up-regulated in Crohn's disease
-
Monteleone, G., Trapasso, F., Parrello, T et al. Bioactive IL-18 expression is up-regulated in Crohn's disease. J Immunol 1999, 163(1): 143-7.
-
(1999)
J Immunol
, vol.163
, Issue.1
, pp. 143-147
-
-
Monteleone, G.1
Trapasso, F.2
Parrello, T.3
-
78
-
-
4644367878
-
Commentary: The role of the IL-18 system and other members of the IL-1R/TLR superfemily in innate mucosal immunity and the pathogenesis of inflammatory bowel disease: Friend of foe?
-
Reuter, B.K. and Pizarro, T.T. Commentary: The role of the IL-18 system and other members of the IL-1R/TLR superfemily in innate mucosal immunity and the pathogenesis of inflammatory bowel disease: Friend of foe? Eur J Immunol 2004, 34(9): 2347-55.
-
(2004)
Eur J Immunol
, vol.34
, Issue.9
, pp. 2347-2355
-
-
Reuter, B.K.1
Pizarro, T.T.2
-
79
-
-
15044349680
-
Therapeutic approaches in inflammatory bowel disease based on the immunopathogenesis
-
Siegmund, B. and Zeitz, M. Therapeutic approaches in inflammatory bowel disease based on the immunopathogenesis. Rocz Akad Med Bialymst 2004, 49: 22-30.
-
(2004)
Rocz Akad Med Bialymst
, vol.49
, pp. 22-30
-
-
Siegmund, B.1
Zeitz, M.2
-
80
-
-
0032771184
-
Cytokine-based therapies in inflammatory bowel disease
-
Kam, L.Y. and Targan. S.R. Cytokine-based therapies in inflammatory bowel disease. Curr Opin Gastroenterol 1999, 15(4): 302-7.
-
(1999)
Curr Opin Gastroenterol
, vol.15
, Issue.4
, pp. 302-307
-
-
Kam, L.Y.1
Targan, S.R.2
-
81
-
-
0030777296
-
Active stage of autoimmune diabetes is associated with the expression of a novel cytokine IGIF, which is located near Idd2
-
Rothe, H., Jenkins, N.A., Copeland, N.G. et al. Active stage of autoimmune diabetes is associated with the expression of a novel cytokine IGIF, which is located near Idd2. J Clin Invest 1997, 99(3): 469-74.
-
(1997)
J Clin Invest
, vol.99
, Issue.3
, pp. 469-474
-
-
Rothe, H.1
Jenkins, N.A.2
Copeland, N.G.3
-
82
-
-
0033178614
-
IL-18 inhibits diabetes development in nonobese diabetic mice by counterregulation of Th1-dependent destructive insuli ns
-
Rothe, H., Hausmann, A., Casteels, K. et al. IL-18 inhibits diabetes development in nonobese diabetic mice by counterregulation of Th1-dependent destructive insuli ns. J Immunol 1999, 163(3): 1230-36.
-
(1999)
J Immunol
, vol.163
, Issue.3
, pp. 1230-1236
-
-
Rothe, H.1
Hausmann, A.2
Casteels, K.3
-
83
-
-
10744221229
-
Systemic administration of IL-18 promotes diabetes development in young nonobese diabetic mice
-
Oikawa, Y., Shimada, A., Kasuga, A. et al. Systemic administration of IL-18 promotes diabetes development in young nonobese diabetic mice. J Immunol 2003. 171(11): 5865-75.
-
(2003)
J Immunol
, vol.171
, Issue.11
, pp. 5865-5875
-
-
Oikawa, Y.1
Shimada, A.2
Kasuga, A.3
-
84
-
-
0042977338
-
Essential pathogenetic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streplozotocin. Prevention of hyperglycemia and insulilis by recombinant IL-18 binding protein:Fc construct
-
Nicoletti, F., Di Marco, R., Papaccio. G. et al. Essential pathogenetic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streplozotocin. Prevention of hyperglycemia and insulilis by recombinant IL-18 binding protein:Fc construct. Eur J Immunol 2003, 33(8): 2278-86.
-
(2003)
Eur J Immunol
, vol.33
, Issue.8
, pp. 2278-2286
-
-
Nicoletti, F.1
Di Marco, R.2
Papaccio, G.3
-
85
-
-
0347086154
-
Caspase-1 is not required for type 1 diabetes in the NOD mouse
-
Schott, W.H., Haskell, B.D., Tse, H.M. et al. Caspase-1 is not required for type 1 diabetes in the NOD mouse. Diabetes 2004, 53(1): 99-104.
-
(2004)
Diabetes
, vol.53
, Issue.1
, pp. 99-104
-
-
Schott, W.H.1
Haskell, B.D.2
Tse, H.M.3
-
86
-
-
0035081444
-
Serum levels of the interferon-γ-inducing cytokine interleukin-18 are increased in individuals at high risk of developing type I diabetes
-
Nicoletti, F., Conget, I., Di Marco, R. et al. Serum levels of the interferon-γ-inducing cytokine interleukin-18 are increased in individuals at high risk of developing type I diabetes. Diabetologia 2001, 44(3): 309-11.
-
(2001)
Diabetologia
, vol.44
, Issue.3
, pp. 309-311
-
-
Nicoletti, F.1
Conget, I.2
Di Marco, R.3
-
87
-
-
0346728704
-
Association between IL-18 gene promoter polymorphisms and CTLA-4 gene 49A/G polymorphism in Japanese patients with type I diabetes
-
Ide, A., Kawasaki, E., Abiru, N. et al. Association between IL-18 gene promoter polymorphisms and CTLA-4 gene 49A/G polymorphism in Japanese patients with type I diabetes. J Autoimmun 2004, 22(1): 73-8.
-
(2004)
J Autoimmun
, vol.22
, Issue.1
, pp. 73-78
-
-
Ide, A.1
Kawasaki, E.2
Abiru, N.3
-
88
-
-
0036829539
-
Interleukin-18 promoter polymorphisms in type 1 diabetes
-
Kretowski, A., Mironczuk, K., Karpinska, A. et al. Interleukin-18 promoter polymorphisms in type 1 diabetes. Diabetes 2002, 51(11): 3347-9.
-
(2002)
Diabetes
, vol.51
, Issue.11
, pp. 3347-3349
-
-
Kretowski, A.1
Mironczuk, K.2
Karpinska, A.3
-
89
-
-
0029034118
-
Multiple sclerosis: A unique immunopathological syndrome of the central nervous system
-
Hunter, S.F. and Rodrigez, M. Multiple sclerosis: A unique immunopathological syndrome of the central nervous system. Springer Semin Immunopathol 1995, 17(1): 89-105.
-
(1995)
Springer Semin Immunopathol
, vol.17
, Issue.1
, pp. 89-105
-
-
Hunter, S.F.1
Rodrigez, M.2
-
90
-
-
0025013169
-
Autoreactive T lymphocytes in multiple sclerosis determined by antigen-induced secretion of interferon-γ
-
Olsson, T., Zhi, W.W., Hojebcrg, B. et al. Autoreactive T lymphocytes in multiple sclerosis determined by antigen-induced secretion of interferon-γ. J Clin Invest 1990, 86(3): 981-5.
-
(1990)
J Clin Invest
, vol.86
, Issue.3
, pp. 981-985
-
-
Olsson, T.1
Zhi, W.W.2
Hojebcrg, B.3
-
91
-
-
0032400918
-
Neutralizing antibodies to IFN-γ-inducing factor prevent experimental autoimmune encephalomyelitis
-
Wildbaum, G., Youssef, S., Grabie, N. and Karin, N. Neutralizing antibodies to IFN-γ-inducing factor prevent experimental autoimmune encephalomyelitis. J Immunol 1998, 161(11): 6368-74.
-
(1998)
J Immunol
, vol.161
, Issue.11
, pp. 6368-6374
-
-
Wildbaum, G.1
Youssef, S.2
Grabie, N.3
Karin, N.4
-
92
-
-
0032476702
-
Differential induction of interleukin-12, interleukin-18, and interleukin-1β converting enzyme mRNA in experimental autoimmune encephalomyelitis of the Lewis rat
-
Jander, S. and Stoll, G. Differential induction of interleukin-12, interleukin-18, and interleukin-1β converting enzyme mRNA in experimental autoimmune encephalomyelitis of the Lewis rat. J Neuroimmunol 1998, 91(1-2): 93-9.
-
(1998)
J Neuroimmunol
, vol.91
, Issue.1-2
, pp. 93-99
-
-
Jander, S.1
Stoll, G.2
-
93
-
-
0033458806
-
The critical role of IL-12 and IL-12Rβ2 subunit in the generation of pathogenic autoreactive Th1 cells
-
Shevach, E.M., Chang, J.T. and Segal, B.M. The critical role of IL-12 and IL-12Rβ2 subunit in the generation of pathogenic autoreactive Th1 cells. Springer Semin Immunopathol 1999. 21(3): 249-62.
-
(1999)
Springer Semin Immunopathol
, vol.21
, Issue.3
, pp. 249-262
-
-
Shevach, E.M.1
Chang, J.T.2
Segal, B.M.3
-
94
-
-
0028966091
-
Prevention of experimental autoimmune encephalomyelitis by anti-bodies against interleukin 12
-
Leonard, J.P.. Waldburger, K.E. and Goldman, S.J. Prevention of experimental autoimmune encephalomyelitis by anti-bodies against interleukin 12. J Exp Med 1995, 181(1): 381-6.
-
(1995)
J Exp Med
, vol.181
, Issue.1
, pp. 381-386
-
-
Leonard, J.P.1
Waldburger, K.E.2
Goldman, S.J.3
-
95
-
-
0033198269
-
Caspase-1 regulates the inflammatory process leading to autoimmune demyelinalion
-
Furlan, R., Martino, G., Galbiati, F. et al. Caspase-1 regulates the inflammatory process leading to autoimmune demyelinalion. J Immunol 1999, 163(5): 2403-9.
-
(1999)
J Immunol
, vol.163
, Issue.5
, pp. 2403-2409
-
-
Furlan, R.1
Martino, G.2
Galbiati, F.3
-
96
-
-
0032702860
-
Peripheral levels of caspase-1 mRNA correlate with disease activity in patients with multiple sclerosis: A preliminary study
-
Furlan, R., Filippi, M., Bergami. A. et al. Peripheral levels of caspase-1 mRNA correlate with disease activity in patients with multiple sclerosis: A preliminary study. J Neurol Neurosurg Psychiatry 1999, 67(6): 785-8.
-
(1999)
J Neurol Neurosurg Psychiatry
, vol.67
, Issue.6
, pp. 785-788
-
-
Furlan, R.1
Filippi, M.2
Bergami, A.3
-
97
-
-
0027537389
-
Systemic lupus erythematosus: Clinical and immunologic patterns of disease expression in a cohort of 1000 patients
-
Cervera, R., Khamasahta, M.A., Font, J. et al. Systemic lupus erythematosus: Clinical and immunologic patterns of disease expression in a cohort of 1000 patients. The European Working party on systemic lupus erythematosus. Medicine (Baltimore) 1993, 72(2): 113-24.
-
(1993)
The European Working party on systemic lupus erythematosus. Medicine (Baltimore)
, vol.72
, Issue.2
, pp. 113-124
-
-
Cervera, R.1
Khamasahta, M.A.2
Font, J.3
-
98
-
-
0035500546
-
A proinflammatory role of IL-18 in the development of spontaneous autoimmuine disease
-
Esfandiari, E., McInnes, I.B., Lindop, G. et al. A proinflammatory role of IL-18 in the development of spontaneous autoimmuine disease. J Immunol 2001, 167(9): 5338-47.
-
(2001)
J Immunol
, vol.167
, Issue.9
, pp. 5338-5347
-
-
Esfandiari, E.1
McInnes, I.B.2
Lindop, G.3
-
99
-
-
4644286915
-
Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis
-
Calvani, N., Richards, H.B., Tucci, M., Pannarale, G. and Silvestris, F. Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis. Clin Exp Immunol 2004, 138(1): 171-8.
-
(2004)
Clin Exp Immunol
, vol.138
, Issue.1
, pp. 171-178
-
-
Calvani, N.1
Richards, H.B.2
Tucci, M.3
Pannarale, G.4
Silvestris, F.5
-
100
-
-
0036846099
-
Correlation of renal tubular epithelial cell-derived interleukin-18 up-regulation with disease activity in MRL-Faslpr mice with autoimmune lupus nephritis
-
Faust, J., Menke, J., Kriegsmann, J. et al. Correlation of renal tubular epithelial cell-derived interleukin-18 up-regulation with disease activity in MRL-Faslpr mice with autoimmune lupus nephritis. Arthritis Rheum 2002, 46(11): 3083-95.
-
(2002)
Arthritis Rheum
, vol.46
, Issue.11
, pp. 3083-3095
-
-
Faust, J.1
Menke, J.2
Kriegsmann, J.3
-
101
-
-
0036408785
-
Elevated production of interleukin-18 is associated with renal disease in patients with systemic lupus erythematosus
-
Wong, C.K., Ho, C.Y., Li, E.k., Tarn, L.S. and Law, C.W. Elevated production of interleukin-18 is associated with renal disease in patients with systemic lupus erythematosus. Clin Exp Immunol 2002, 130(2): 345-51.
-
(2002)
Clin Exp Immunol
, vol.130
, Issue.2
, pp. 345-351
-
-
Wong, C.K.1
Ho, C.Y.2
Li, E.K.3
Tarn, L.S.4
Law, C.W.5
-
102
-
-
0034882184
-
Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-γ, IL-4, IL-I0 and IL-13) in patients with allergic asthma
-
Wong, C.K., Ho, C.y., Ko, F.w. et al. Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-γ, IL-4, IL-I0 and IL-13) in patients with allergic asthma. Clin Exp Immunol 2001, 125(2): 177-83.
-
(2001)
Clin Exp Immunol
, vol.125
, Issue.2
, pp. 177-183
-
-
Wong, C.K.1
Ho, C.Y.2
Ko, F.W.3
-
103
-
-
0035110203
-
IL-18 might reflect disease activity in mild and moderate asthma exacerbation
-
Tanaka, H., Miyazaki, N., Oashi, K. et al. IL-18 might reflect disease activity in mild and moderate asthma exacerbation. J Allergy Clin Immunol 2001, 107(2): 331-6.
-
(2001)
J Allergy Clin Immunol
, vol.107
, Issue.2
, pp. 331-336
-
-
Tanaka, H.1
Miyazaki, N.2
Oashi, K.3
-
104
-
-
0034084067
-
IL-18 prevents the development of chronic graft-versus-host disease in mice
-
Okamoto, I., Kohno, K., Tanimoto, T. et al. IL-18 prevents the development of chronic graft-versus-host disease in mice. J Immunol 2000, 164(11): 6067-74.
-
(2000)
J Immunol
, vol.164
, Issue.11
, pp. 6067-6074
-
-
Okamoto, I.1
Kohno, K.2
Tanimoto, T.3
-
105
-
-
0032720802
-
Kinetics of interferon-γ secretion and its regulatory factors in the early phase of acute graft-versus-host disease
-
Hu, H.Z., Li, G.L., Lim, Y.K., Chan, S.H. and Yap, E.H. Kinetics of interferon-γ secretion and its regulatory factors in the early phase of acute graft-versus-host disease. Imunology 1999, 98(3): 379-85.
-
(1999)
Imunology
, vol.98
, Issue.3
, pp. 379-385
-
-
Hu, H.Z.1
Li, G.L.2
Lim, Y.K.3
Chan, S.H.4
Yap, E.H.5
-
106
-
-
0035412376
-
Fas ligand-induced caspase-I-dependent accumulation of interleukin-18 in mice with acute graft-versus-host disease
-
Itoi, H., Fujimori, Y., Tsutsui, H. et al. Fas ligand-induced caspase-I-dependent accumulation of interleukin-18 in mice with acute graft-versus-host disease. Blood 2001, 98(1): 235-7.
-
(2001)
Blood
, vol.98
, Issue.1
, pp. 235-237
-
-
Itoi, H.1
Fujimori, Y.2
Tsutsui, H.3
-
107
-
-
0034096337
-
Elevated interleukin (IL)-18 levels during acute graft-versus-host disease after allogeneic bone marrow transplantation
-
Fujimori, Y., Takatsuka, H., Takemoto, Y. et al. Elevated interleukin (IL)-18 levels during acute graft-versus-host disease after allogeneic bone marrow transplantation. Br J Haematol 2000, 109(3): 652-7.
-
(2000)
Br J Haematol
, vol.109
, Issue.3
, pp. 652-657
-
-
Fujimori, Y.1
Takatsuka, H.2
Takemoto, Y.3
-
108
-
-
0035686080
-
Interleukin-18 binding protein in acute graft versus host disease and engraftment following allogeneic peripheral blood stem cell transplants
-
Zecchina, G., Novick, D., Rubinstein, M. et al. Interleukin-18 binding protein in acute graft versus host disease and engraftment following allogeneic peripheral blood stem cell transplants. J Hematother Stem Cell Res 2001, 10(6): 769-76.
-
(2001)
J Hematother Stem Cell Res
, vol.10
, Issue.6
, pp. 769-776
-
-
Zecchina, G.1
Novick, D.2
Rubinstein, M.3
-
109
-
-
2442557879
-
Differential upregulation of interleukin-18 receptor α chain between CD4+ and CDS+ T cells during acute graft-versus-host disease in mice
-
Itoi, H., Fujimori, Y., Tsutsui, H. et al. Differential upregulation of interleukin-18 receptor α chain between CD4+ and CDS+ T cells during acute graft-versus-host disease in mice. J Interferon Cytokine Res 2004, 24(5): 291-6.
-
(2004)
J Interferon Cytokine Res
, vol.24
, Issue.5
, pp. 291-296
-
-
Itoi, H.1
Fujimori, Y.2
Tsutsui, H.3
-
110
-
-
1242293661
-
Serum interleukin-12 and interleukin-18 levels as a tumor marker in patients with ezophageal carcinoma
-
Tsuboi, K., Miyazaki, T., Nakajima, M. et al. Serum interleukin-12 and interleukin-18 levels as a tumor marker in patients with ezophageal carcinoma. Cancer Lett 2004, 205(2): 207-14.
-
(2004)
Cancer Lett
, vol.205
, Issue.2
, pp. 207-214
-
-
Tsuboi, K.1
Miyazaki, T.2
Nakajima, M.3
-
111
-
-
33644586895
-
Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimens: Implications for survival
-
Bellone, G., Smirne, C., Mauri, F.A. et al. Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimens: Implications for survival. Cancer Immunol Immunother 2006, 55(6): 684-98.
-
(2006)
Cancer Immunol Immunother
, vol.55
, Issue.6
, pp. 684-698
-
-
Bellone, G.1
Smirne, C.2
Mauri, F.A.3
-
112
-
-
30444461349
-
Role of interleukin-18 and its receptor in hepatocellular carcinoma associated with hepatitis C virus infection
-
Asakawa, M., Kono, H., Amemiya, H. et al. Role of interleukin-18 and its receptor in hepatocellular carcinoma associated with hepatitis C virus infection. Int J Cancer 2006, 118(3): 564-70.
-
(2006)
Int J Cancer
, vol.118
, Issue.3
, pp. 564-570
-
-
Asakawa, M.1
Kono, H.2
Amemiya, H.3
-
113
-
-
1442354134
-
Manheim Alcohol Study Group. Expression of IL-18 in patients with head and neck squamous cell carcinoma
-
Riedel, F., Adam, S., Feick, P. et al. Manheim Alcohol Study Group. Expression of IL-18 in patients with head and neck squamous cell carcinoma. Int J Mol Med 2004, 13(2): 267-72.
-
(2004)
Int J Mol Med
, vol.13
, Issue.2
, pp. 267-272
-
-
Riedel, F.1
Adam, S.2
Feick, P.3
-
114
-
-
0034873384
-
Serum levels of Interleukin-18 and slCAM-I in patients affected by breast cancer: Preliminary considerations
-
Merendino, R.A., Gangemi, S., Ruello, A. et al. Serum levels of Interleukin-18 and slCAM-I in patients affected by breast cancer: Preliminary considerations. Int J Biol Markers 2001, 16(2): 126-29.
-
(2001)
Int J Biol Markers
, vol.16
, Issue.2
, pp. 126-129
-
-
Merendino, R.A.1
Gangemi, S.2
Ruello, A.3
-
115
-
-
1842683883
-
Impact of serum Interleukin-18 level as a prognostic indicator in patients with epithelial ovarian carcinoma
-
Akahiro, J., Konno, R., Ito, K. et al. Impact of serum Interleukin-18 level as a prognostic indicator in patients with epithelial ovarian carcinoma. Int J Clin Oncol 2004, 9(1): 42-6.
-
(2004)
Int J Clin Oncol
, vol.9
, Issue.1
, pp. 42-46
-
-
Akahiro, J.1
Konno, R.2
Ito, K.3
-
116
-
-
0033757837
-
Urinary interleukin-8 and 18 predict the response of superficial bladder cancer to intravesical therapy with bacillus Calmette Guerin
-
Thalmann, G., Sermier, A., Rentsch, C. et al. Urinary interleukin-8 and 18 predict the response of superficial bladder cancer to intravesical therapy with bacillus Calmette Guerin. J Urol 2000, 164(6): 2129-33.
-
(2000)
J Urol
, vol.164
, Issue.6
, pp. 2129-2133
-
-
Thalmann, G.1
Sermier, A.2
Rentsch, C.3
-
117
-
-
1342322968
-
Serum levels of interleukin-18 and nitrite+nitrate in renal cell carcinoma patients with different tumor stage and grade
-
Sozen, S., Coskun, U., Sancak, B. et al. Serum levels of interleukin-18 and nitrite+nitrate in renal cell carcinoma patients with different tumor stage and grade. Neoplasma 2004, 51(1): 25-9.
-
(2004)
Neoplasma
, vol.51
, Issue.1
, pp. 25-29
-
-
Sozen, S.1
Coskun, U.2
Sancak, B.3
-
118
-
-
0036348548
-
Clinical significance of IL-18 gene overexpression in AML
-
Zhang, B., Wang, Y., Zheng, G.G. et al. Clinical significance of IL-18 gene overexpression in AML. Leuk Res 2002, 26(10): 887-92.
-
(2002)
Leuk Res
, vol.26
, Issue.10
, pp. 887-892
-
-
Zhang, B.1
Wang, Y.2
Zheng, G.G.3
-
119
-
-
33845536395
-
Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression
-
Vidal-Vanaclocha, F., Mendoza, L., Telleria, N. et al. Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression. Cancer Metastasis Rev 2006, 25(3): 417-34.
-
(2006)
Cancer Metastasis Rev
, vol.25
, Issue.3
, pp. 417-434
-
-
Vidal-Vanaclocha, F.1
Mendoza, L.2
Telleria, N.3
-
120
-
-
0033994272
-
Interleukin-18 in combination with IL-2 enhances natural killer cell activity without inducing large amounts of IFN-γ in vivo
-
Arai, N., Akamatsu, S., Arai, S. et al. Interleukin-18 in combination with IL-2 enhances natural killer cell activity without inducing large amounts of IFN-γ in vivo. J Interferon Cytokine Res 2000, 20(2): 217-24.
-
(2000)
J Interferon Cytokine Res
, vol.20
, Issue.2
, pp. 217-224
-
-
Arai, N.1
Akamatsu, S.2
Arai, S.3
-
121
-
-
2642674449
-
IFNγ-inducing factor/IL-18 administration mediates IFNγ- and IL-12-independent anti-tumor effects
-
Osaki, T., Peron, J.M., Cai, Q. et al. IFNγ-inducing factor/IL-18 administration mediates IFNγ- and IL-12-independent anti-tumor effects. J Immunol 1998, 160(4): 1742-49.
-
(1998)
J Immunol
, vol.160
, Issue.4
, pp. 1742-1749
-
-
Osaki, T.1
Peron, J.M.2
Cai, Q.3
-
122
-
-
0036901999
-
Additive effect of Interleukin-12 and Interleukin-18 on the T-helper cell pathway of malignant pleural effusion
-
Yao, N.S., Chen, Y.M., Perng, R.P. and Whang-Peng, J. Additive effect of Interleukin-12 and Interleukin-18 on the T-helper cell pathway of malignant pleural effusion. Lung 2002, 180(1): 15-24.
-
(2002)
Lung
, vol.180
, Issue.1
, pp. 15-24
-
-
Yao, N.S.1
Chen, Y.M.2
Perng, R.P.3
Whang-Peng, J.4
-
123
-
-
0035175668
-
Nitric oxide synthase inhibitor and IL-18 enhance the anti-tumor immune response of rats carrying an intrahepatic color carcinoma
-
Hegardt, P., Widegren, B., Li, L. et al. Nitric oxide synthase inhibitor and IL-18 enhance the anti-tumor immune response of rats carrying an intrahepatic color carcinoma. Cancer Immunol Immunother 2001, 50(9): 491-501.
-
(2001)
Cancer Immunol Immunother
, vol.50
, Issue.9
, pp. 491-501
-
-
Hegardt, P.1
Widegren, B.2
Li, L.3
-
124
-
-
0036216980
-
Influence of 5-fluorouracil and folinic acid on interleukin-18 production in colorectal cancer patients
-
Merendino, R.A., Ruello, A., Cascinu, S. et al. Influence of 5-fluorouracil and folinic acid on interleukin-18 production in colorectal cancer patients. Int J Biol Markers 2002, 17(1): 63-6.
-
(2002)
Int J Biol Markers
, vol.17
, Issue.1
, pp. 63-66
-
-
Merendino, R.A.1
Ruello, A.2
Cascinu, S.3
-
125
-
-
33645542090
-
Interleukins 18 and 21 : Biology, mechanisms of action, toxicity, and clinical activity
-
Logan, T.F. and Robertson, M.J. Interleukins 18 and 21 : biology, mechanisms of action, toxicity, and clinical activity. Curr Oncol Rep 2006, 8(2): 114-9.
-
(2006)
Curr Oncol Rep
, vol.8
, Issue.2
, pp. 114-119
-
-
Logan, T.F.1
Robertson, M.J.2
-
126
-
-
0035424134
-
Evidence of IL-18 as a novel angiogenic mediator
-
Park, C.C., Morel, J.C., Amin, M.A. et al. Evidence of IL-18 as a novel angiogenic mediator. J Immunol 2001, 167(3): 1644-53.
-
(2001)
J Immunol
, vol.167
, Issue.3
, pp. 1644-1653
-
-
Park, C.C.1
Morel, J.C.2
Amin, M.A.3
-
127
-
-
0037148510
-
Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, and macrophages: Implications for athero-genesis
-
Gerdes, N., Sukhova, G.K., Libby, P. et al. Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, and macrophages: Implications for athero-genesis. J Exp Med 2002, 195(2): 245-57.
-
(2002)
J Exp Med
, vol.195
, Issue.2
, pp. 245-257
-
-
Gerdes, N.1
Sukhova, G.K.2
Libby, P.3
-
128
-
-
0347626018
-
Interleukin-18 in multiple myeloma patients: Serum levels in relation to response to treatment and survival
-
Alexandrakis, M.G., Passam, F.H., Sfiridaki, K. et al. Interleukin-18 in multiple myeloma patients: Serum levels in relation to response to treatment and survival. Leuk Res 2004, 28(3): 259-66.
-
(2004)
Leuk Res
, vol.28
, Issue.3
, pp. 259-266
-
-
Alexandrakis, M.G.1
Passam, F.H.2
Sfiridaki, K.3
-
129
-
-
0141605844
-
Cytokine-induced inflammatory liver injuries
-
Tsutsui, H., Adachi, K., Seki, E. and Nakanishi, K. Cytokine-induced inflammatory liver injuries. Curr Mol Med 2003, 3(6): 545-59.
-
(2003)
Curr Mol Med
, vol.3
, Issue.6
, pp. 545-559
-
-
Tsutsui, H.1
Adachi, K.2
Seki, E.3
Nakanishi, K.4
-
130
-
-
10244240498
-
Biologic markers for the early detection of acute kidney injury
-
Han, W.K. and Bonventre, J.V. Biologic markers for the early detection of acute kidney injury. Curr Opin Crit Care 2004, 10(6): 476-82.
-
(2004)
Curr Opin Crit Care
, vol.10
, Issue.6
, pp. 476-482
-
-
Han, W.K.1
Bonventre, J.V.2
-
131
-
-
16244376236
-
When interleukin-18 conducts, the Preludio sounds the same no matter who plays
-
Caligiuri, G., Kaveri, S. and Nicoletti, A. When interleukin-18 conducts, the Preludio sounds the same no matter who plays. Arterioscler Thromb Vase Biol 2005, 25(4): 655-7.
-
(2005)
Arterioscler Thromb Vase Biol
, vol.25
, Issue.4
, pp. 655-657
-
-
Caligiuri, G.1
Kaveri, S.2
Nicoletti, A.3
-
132
-
-
0037679086
-
Interleukin 18 and interleukin 18 binding protein: Possible role in immunosuppression of chronic renal failure
-
Dinarello, C.A., Novick, D., Rubinstein, M. and Lonnemann, G. Interleukin 18 and interleukin 18 binding protein: Possible role in immunosuppression of chronic renal failure. Blood Purif 2003, 21(3): 258-70.
-
(2003)
Blood Purif
, vol.21
, Issue.3
, pp. 258-270
-
-
Dinarello, C.A.1
Novick, D.2
Rubinstein, M.3
Lonnemann, G.4
-
133
-
-
0033974776
-
Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18
-
Kim, S.H., Eisenstein, M., Reznikov, L. et al. Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18. Proc Natl Acad Sci U S A 2000, 97(3): 1190-5.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.3
, pp. 1190-1195
-
-
Kim, S.H.1
Eisenstein, M.2
Reznikov, L.3
-
134
-
-
0032983336
-
Interleukin-18 binding protein: A novel modulator of the Th1 cytokine response
-
Novick, D., Kim, S.H., Fantuzzi, G. et al. Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. Immunity 1999, 10(1): 127-36.
-
(1999)
Immunity
, vol.10
, Issue.1
, pp. 127-136
-
-
Novick, D.1
Kim, S.H.2
Fantuzzi, G.3
-
135
-
-
0035664487
-
Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis
-
Plater-Zyberk, C., Joosten, L.A., Helsen, M.M. et al. Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis. J Clin Invest 2001, 108(12): 1825-32.
-
(2001)
J Clin Invest
, vol.108
, Issue.12
, pp. 1825-1832
-
-
Plater-Zyberk, C.1
Joosten, L.A.2
Helsen, M.M.3
-
136
-
-
0037442112
-
Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein
-
Banda, N.K., Vondracek, A., Kraus, D. et al. Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein. J Immunol 2003, 170(4): 2100-5.
-
(2003)
J Immunol
, vol.170
, Issue.4
, pp. 2100-2105
-
-
Banda, N.K.1
Vondracek, A.2
Kraus, D.3
-
137
-
-
0036103112
-
Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: Blocking interleukin 18 attenuates intestinal damage
-
Sivakumar, P.V., Westrich, G.M., Kanaly, S. et al. Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: Blocking interleukin 18 attenuates intestinal damage. Gut 2002, 50(6): 812-20.
-
(2002)
Gut
, vol.50
, Issue.6
, pp. 812-820
-
-
Sivakumar, P.V.1
Westrich, G.M.2
Kanaly, S.3
-
138
-
-
0038685647
-
Adenoviral delivery of IL-18 binding protein C ameliorates collagen-induced arthritis in mice
-
Smeets, R.L., van de Loo, F.A., Amtz, O.J. et al. Adenoviral delivery of IL-18 binding protein C ameliorates collagen-induced arthritis in mice. Gene Ther 2003, 10(12): 1004-11.
-
(2003)
Gene Ther
, vol.10
, Issue.12
, pp. 1004-1011
-
-
Smeets, R.L.1
van de Loo, F.A.2
Amtz, O.J.3
-
139
-
-
0034795561
-
Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production
-
Siegmund, B., Fantuzzi, G., Rieder, F. et al. Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production. Am J Physiol Regul Integr Comp Physiol 2001 281(4): R1264-73.
-
(2001)
Am J Physiol Regul Integr Comp Physiol
, vol.281
, Issue.4
-
-
Siegmund, B.1
Fantuzzi, G.2
Rieder, F.3
-
140
-
-
18144390563
-
IL-18 binding protein fusion construct delays the development of diabetes in adoptive transfer and cyclophosphamide-induced diabetes in NOD mouse
-
Zaccone, P., Phillips, J., Conget, I., Cooke, A. and Nicoletti, F. IL-18 binding protein fusion construct delays the development of diabetes in adoptive transfer and cyclophosphamide-induced diabetes in NOD mouse. Clin Immunol 2005, 115(1): 74-9.
-
(2005)
Clin Immunol
, vol.115
, Issue.1
, pp. 74-79
-
-
Zaccone, P.1
Phillips, J.2
Conget, I.3
Cooke, A.4
Nicoletti, F.5
-
141
-
-
3042545963
-
Therapeutic potential of targeting IL-1 and IL-18 in inflammation
-
Braddock, M., Quinn, A. and Canvin, J. Therapeutic potential of targeting IL-1 and IL-18 in inflammation. Expert Opin Biol Ther 2004, 4(6): 847-60.
-
(2004)
Expert Opin Biol Ther
, vol.4
, Issue.6
, pp. 847-860
-
-
Braddock, M.1
Quinn, A.2
Canvin, J.3
-
143
-
-
15844393942
-
Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme
-
Yamin, T.T., Ayala, J.M. and Miller, D.K. Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme. J Biol Chem 1996, 271(22): 13273-82.
-
(1996)
J Biol Chem
, vol.271
, Issue.22
, pp. 13273-13282
-
-
Yamin, T.T.1
Ayala, J.M.2
Miller, D.K.3
-
144
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello, C.A. Biologic basis for interleukin-1 in disease. Blood 1996, 87(6): 2095-147.
-
(1996)
Blood
, vol.87
, Issue.6
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
145
-
-
0028953351
-
A synthetic inhibitor of interleukin-1 β converting enzyme prevents endotoxin-induced interleukin-1 β production in vitro and in vivo
-
Fletcher, D.S., Agarwal, L., Chapman, K.T. et al. A synthetic inhibitor of interleukin-1 β converting enzyme prevents endotoxin-induced interleukin-1 β production in vitro and in vivo. J Interferon Cytokine Res 1995, 15(3): 243-48.
-
(1995)
J Interferon Cytokine Res
, vol.15
, Issue.3
, pp. 243-248
-
-
Fletcher, D.S.1
Agarwal, L.2
Chapman, K.T.3
-
146
-
-
0030013088
-
The inflammatory response in interleukin-1 β-deficient mice: Comparison with other cytokine-related knock-out mice
-
Fantuzzi, G. and Dinarello, C.A. The inflammatory response in interleukin-1 β-deficient mice: Comparison with other cytokine-related knock-out mice. J Leukoc Biol 1996, 59(4): 489-93.
-
(1996)
J Leukoc Biol
, vol.59
, Issue.4
, pp. 489-493
-
-
Fantuzzi, G.1
Dinarello, C.A.2
-
147
-
-
0032521457
-
Interleukin-18 regulation of interferon γ production and cell proliferation as shown in interleukin-1 β-converting enzyme (caspase-I)-deficient mice
-
Fantuzzi, G., Puren, A.J., Harding, M.W., Livingston, D.J. and Dinarello, C.A. Interleukin-18 regulation of interferon γ production and cell proliferation as shown in interleukin-1 β-converting enzyme (caspase-I)-deficient mice. Blood 1998, 91(6): 2118-25.
-
(1998)
Blood
, vol.91
, Issue.6
, pp. 2118-2125
-
-
Fantuzzi, G.1
Puren, A.J.2
Harding, M.W.3
Livingston, D.J.4
Dinarello, C.A.5
-
148
-
-
0028984948
-
Mice deficient in IL-1 β-converting enzyme are defective in production of mature IL-1 β and resistant to endotoxic shock
-
Li, P., Allen, H., Banerjee, S. et al. Mice deficient in IL-1 β-converting enzyme are defective in production of mature IL-1 β and resistant to endotoxic shock. Cell 1995, 80(3): 401-11.
-
(1995)
Cell
, vol.80
, Issue.3
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
-
149
-
-
0031044777
-
Characterization of mice deficient in interleukin-1 β converting enzyme
-
Li, P., Allen, H., Banerjee, S. and Seshadri, T. Characterization of mice deficient in interleukin-1 β converting enzyme. J Cell Biochem 1997, 64(1): 27-32.
-
(1997)
J Cell Biochem
, vol.64
, Issue.1
, pp. 27-32
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Seshadri, T.4
-
150
-
-
0035818549
-
IL-1 β-converting enzyme (caspase-1) in intestinal inflammation
-
Siegmund, B., Lehr, H.A., Fantuzzi, G. and Dinarello, C.A. IL-1 β-converting enzyme (caspase-1) in intestinal inflammation. Proc Natl Acad Sci U S A 2001, 98(23): 13249-54.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.23
, pp. 13249-13254
-
-
Siegmund, B.1
Lehr, H.A.2
Fantuzzi, G.3
Dinarello, C.A.4
-
151
-
-
9144222968
-
The interleukin-1 β-converting enzyme inhibitor pralnacasan reduces dextran sulfate sodium-induced murine colitis and T helper 1 T-cell activation
-
Loher, F., Bauer, C., Landauer, N. et al. The interleukin-1 β-converting enzyme inhibitor pralnacasan reduces dextran sulfate sodium-induced murine colitis and T helper 1 T-cell activation. J Pharmacol Exp Ther 2004, 308(2): 583-90.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, Issue.2
, pp. 583-590
-
-
Loher, F.1
Bauer, C.2
Landauer, N.3
-
152
-
-
0034929774
-
ICE/Caspase-1 inhibitors as novel anti-inflammatory drugs
-
Randle, J.C., Harding, M. W., Ku, G., Schonharting, M. and Kurrle, R. ICE/Caspase-1 inhibitors as novel anti-inflammatory drugs. Expert Opin Investig Drugs 2001, 10(7): 1207-9.
-
(2001)
Expert Opin Investig Drugs
, vol.10
, Issue.7
, pp. 1207-1209
-
-
Randle, J.C.1
Harding, M.W.2
Ku, G.3
Schonharting, M.4
Kurrle, R.5
-
153
-
-
0028170376
-
Structure and mechanism of interleukin-1 β converting enzyme
-
Wilson, K.P., Black, J.A., Thomson, J.A. et al. Structure and mechanism of interleukin-1 β converting enzyme. Nature 1994, 370(6487): 270-5.
-
(1994)
Nature
, vol.370
, Issue.6487
, pp. 270-275
-
-
Wilson, K.P.1
Black, J.A.2
Thomson, J.A.3
-
154
-
-
0037295235
-
Pralnacasan (Vertex Pharmaceuticals)
-
Siegmund, B. and Zeitz, M. Pralnacasan (Vertex Pharmaceuticals). IDrugs 2003, 6(2): 154-8.
-
(2003)
IDrugs
, vol.6
, Issue.2
, pp. 154-158
-
-
Siegmund, B.1
Zeitz, M.2
-
155
-
-
0032731690
-
Etanercept: Therapeutic use in patients with rheumatoid arthritis
-
Garrison, L. and McDonnell, N.D. Etanercept: Therapeutic use in patients with rheumatoid arthritis. Ann Rheum 1999, 58: 165-9.
-
(1999)
Ann Rheum
, vol.58
, pp. 165-169
-
-
Garrison, L.1
McDonnell, N.D.2
-
156
-
-
0033198677
-
Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from-macrophages causes acute liver injury in mice
-
Tsutsui, H., Kayagaki, N., Kuida, K. et al. Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from-macrophages causes acute liver injury in mice. Immunity 1999, 11(3): 359-67.
-
(1999)
Immunity
, vol.11
, Issue.3
, pp. 359-367
-
-
Tsutsui, H.1
Kayagaki, N.2
Kuida, K.3
-
157
-
-
0023947763
-
Generation of biologicallly active interleukin-1 β by proteolitic cleavage of the inactive precursor
-
Black, R.A., Kronheim, S.R., Cantrell, M. et al. Generation of biologicallly active interleukin-1 β by proteolitic cleavage of the inactive precursor. J Biol Chem 1988, 263(19): 9437-42.
-
(1988)
J Biol Chem
, vol.263
, Issue.19
, pp. 9437-9442
-
-
Black, R.A.1
Kronheim, S.R.2
Cantrell, M.3
-
158
-
-
0025220123
-
Processing of precrsor interleukin 1 β and inflammatory disease
-
Hazuda, D.J., Strickler, J., Kueppers, F., Simon, P.L. and Young, P.R. Processing of precrsor interleukin 1 β and inflammatory disease. J Biol Chem 1990, 265(11): 6318-22.
-
(1990)
J Biol Chem
, vol.265
, Issue.11
, pp. 6318-6322
-
-
Hazuda, D.J.1
Strickler, J.2
Kueppers, F.3
Simon, P.L.4
Young, P.R.5
-
159
-
-
0028988261
-
Granzyme A is an interleukin 1 β-converting enzyme
-
Irmler, M., Hertig. S., MacDonald, H.R. et al. Granzyme A is an interleukin 1 β-converting enzyme. J Exp Med 1995, 181(5): 1917-22.
-
(1995)
J Exp Med
, vol.181
, Issue.5
, pp. 1917-1922
-
-
Irmler, M.1
Hertig, S.2
MacDonald, H.R.3
-
160
-
-
0026040529
-
Rapid and specific conversion of precursor interleukin 1 β (IL-1 β) to an active IL-1 species by human mast cell chymase
-
Mizutani, H., Schechter, N., Lazarus, G., Black, R.A. and Kupper, T.S. Rapid and specific conversion of precursor interleukin 1 β (IL-1 β) to an active IL-1 species by human mast cell chymase. J Exp Med 1991, 174(4): 821-25.
-
(1991)
J Exp Med
, vol.174
, Issue.4
, pp. 821-825
-
-
Mizutani, H.1
Schechter, N.2
Lazarus, G.3
Black, R.A.4
Kupper, T.S.5
-
161
-
-
33646072818
-
The P2X7 receptor: A key player in IL-1 processing and release
-
Ferrari, D., Pizzirani, C., Adinolfi, E. et al. The P2X7 receptor: A key player in IL-1 processing and release. J Immunol 2006, 176(7): 3877-83.
-
(2006)
J Immunol
, vol.176
, Issue.7
, pp. 3877-3883
-
-
Ferrari, D.1
Pizzirani, C.2
Adinolfi, E.3
-
162
-
-
20044382685
-
Pharmacological characterization of P2X7 receptors in rat peritoneal cells
-
Chen, Y.W., Donnelly-Roberts, D.L., Namovic, M.T. et al. Pharmacological characterization of P2X7 receptors in rat peritoneal cells. Inflamm Res 2005, 54(3): 119-26.
-
(2005)
Inflamm Res
, vol.54
, Issue.3
, pp. 119-126
-
-
Chen, Y.W.1
Donnelly-Roberts, D.L.2
Namovic, M.T.3
-
163
-
-
0035830853
-
ATP-stimulaled release of interleukin (IL)-1β and IL-18 requires primind by lipopolysaccharide and is independent of caspase-1 cleavage
-
Mehta, V.B., Hart, J. and Wewers, M.D. ATP-stimulaled release of interleukin (IL)-1β and IL-18 requires primind by lipopolysaccharide and is independent of caspase-1 cleavage. J Biol Chem 2001, 276(6): 3820-6.
-
(2001)
J Biol Chem
, vol.276
, Issue.6
, pp. 3820-3826
-
-
Mehta, V.B.1
Hart, J.2
Wewers, M.D.3
-
164
-
-
0034667943
-
ATP acts as an agonist to promote stimulus-induced secretion of IL-1β and IL-18 in human blood
-
Perregaux, D.G., McNiff, P., Laliberte, R., Conklyn, M. and Gabel, C.A. ATP acts as an agonist to promote stimulus-induced secretion of IL-1β and IL-18 in human blood. J Immunol 2000, 165(8): 4615-23.
-
(2000)
J Immunol
, vol.165
, Issue.8
, pp. 4615-4623
-
-
Perregaux, D.G.1
McNiff, P.2
Laliberte, R.3
Conklyn, M.4
Gabel, C.A.5
-
165
-
-
1642493590
-
P2X7 receptor modulation of β-amyloid-and LPS-induced cytokine secretion from human macrophages and microglia
-
Rampe, D., Wang, L. and Ringheim, G.E. P2X7 receptor modulation of β-amyloid-and LPS-induced cytokine secretion from human macrophages and microglia. J Neuroimmunol 2004, 147(1-2): 56-61.
-
(2004)
J Neuroimmunol
, vol.147
, Issue.1-2
, pp. 56-61
-
-
Rampe, D.1
Wang, L.2
Ringheim, G.E.3
-
166
-
-
0029869934
-
Extracellular ATP activates mast cells via a mechanism different from the activation induced by cross-linking of Fc receptors
-
Sudo, N., Tanaka, K., Koga, Y. et al. Extracellular ATP activates mast cells via a mechanism different from the activation induced by cross-linking of Fc receptors. J Immunol 1996, 156(10): 3970-9.
-
(1996)
J Immunol
, vol.156
, Issue.10
, pp. 3970-3979
-
-
Sudo, N.1
Tanaka, K.2
Koga, Y.3
-
168
-
-
0035338445
-
7 nucleotide receptor mediation of membrane pore formation in human promyelocytes and neutrophyls
-
7 nucleotide receptor mediation of membrane pore formation in human promyelocytes and neutrophyls. J Immunol 2001, 166(11): 6754-63.
-
(2001)
J Immunol
, vol.166
, Issue.11
, pp. 6754-6763
-
-
Suh, B.1
Kim, S.2
Namgung, U.3
Ha, H.4
Kim, K.5
-
170
-
-
0035031568
-
Detection of P2X purinergic receptors of human B lymphocytes
-
Sluyter, R., Barden, J.A. and Wiley, J.S. Detection of P2X purinergic receptors of human B lymphocytes. Cell Tissue Res 2001, 304(2): 231-6.
-
(2001)
Cell Tissue Res
, vol.304
, Issue.2
, pp. 231-236
-
-
Sluyter, R.1
Barden, J.A.2
Wiley, J.S.3
-
172
-
-
0033566829
-
7 purinergic receptor: Characterization and possible participation inantigen presentation
-
7 purinergic receptor: Characterization and possible participation inantigen presentation. J Immunol 1999, 163(4): 1958-65.
-
(1999)
J Immunol
, vol.163
, Issue.4
, pp. 1958-1965
-
-
Mutini, C.1
Falzoni, S.2
Ferrari, D.3
-
173
-
-
0035808396
-
Altered cytokine production in mice lacking P2X(7) receptors
-
Solle, M., Labasi, J., Perregaux. D.G. et al. Altered cytokine production in mice lacking P2X(7) receptors. J Biol Chem 2001, 276(1): 125-32.
-
(2001)
J Biol Chem
, vol.276
, Issue.1
, pp. 125-132
-
-
Solle, M.1
Labasi, J.2
Perregaux, D.G.3
-
174
-
-
0037096207
-
Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response
-
Labasi, J.M., Petrushova, N., Donovan, C. et al. Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response. J Immunol 2002, 168(12): 6436-45.
-
(2002)
J Immunol
, vol.168
, Issue.12
, pp. 6436-6445
-
-
Labasi, J.M.1
Petrushova, N.2
Donovan, C.3
-
175
-
-
0036899591
-
Relief of inflammatory pain in rats by local use of the selective P2X7 ATP receptor inhibitor, oxidized ATP
-
Dell'Antonio, G., Quattrini, A., Cin, E.D., Fulgenzi, A. and Ferrero, M.E. Relief of inflammatory pain in rats by local use of the selective P2X7 ATP receptor inhibitor, oxidized ATP. Arthritis Rheum 2002, 46(12): 3378-85.
-
(2002)
Arthritis Rheum
, vol.46
, Issue.12
, pp. 3378-3385
-
-
Dell'Antonio, G.1
Quattrini, A.2
Cin, E.D.3
Fulgenzi, A.4
Ferrero, M.E.5
-
176
-
-
0037135302
-
Antinociceptive effect of a new P(2Z)/P2X7 antagonist, oxidized ATP. in arthritic rats
-
Dell'Antonio, G., Quattrini, A., Dal Cin, E., Fulgenzi, A. and Ferrero, M.E. Antinociceptive effect of a new P(2Z)/P2X7 antagonist, oxidized ATP. in arthritic rats. Neurosci Lett 2002, 327(2): 87-90.
-
(2002)
Neurosci Lett
, vol.327
, Issue.2
, pp. 87-90
-
-
Dell'Antonio, G.1
Quattrini, A.2
Dal Cin, E.3
Fulgenzi, A.4
Ferrero, M.E.5
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