Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response

Journal of Immunology

Volumn 168, Issue 12, 2002, Pages 6436-6445

  Labasi, Jeffrey M ^a   Petrushova, Nina ^a   Donovan, Carol ^a   McCurdy, Sandra ^a   Lira, Paul ^a   Payette, Mary M ^a   Brissette, William ^a   Wicks, Joan R ^a   Audoly, Laurent ^a   Gabel, Christopher A ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; COLLAGEN ANTIBODY; CYTOKINE; INTERLEUKIN 1BETA; ION CHANNEL; L SELECTIN; LIGAND; POLYPEPTIDE; PROTEOGLYCAN; PURINE P2X RECEPTOR; RECEPTOR SUBTYPE; COLLAGEN TYPE 2; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; PURINE P2 RECEPTOR; PURINE P2X7 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; CELL SHAPE; CELL VOLUME; CHANNEL GATING; COLLAGEN DEGRADATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; INFLAMMATION; LEUKOCYTE FUNCTION; LYMPHOCYTE; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVOCATION TEST; ANIMAL; B LYMPHOCYTE; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CELL CULTURE; DBA MOUSE; GENETICS; IMMUNOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; LEUKOCYTE COUNT; METABOLISM; MONONUCLEAR CELL; MOUSE MUTANT; PATHOLOGY; PERITONEUM MACROPHAGE; PHYSIOLOGY; T LYMPHOCYTE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIBODIES, MONOCLONAL; ARTHRITIS, EXPERIMENTAL; B-LYMPHOCYTES; CELLS, CULTURED; COLLAGEN TYPE II; FEMALE; INFLAMMATION; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-1; L-SELECTIN; LEUKOCYTE COUNT; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; MONOCYTES; RECEPTORS, PURINERGIC P2; T-LYMPHOCYTES;

EID: 0037096207     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.12.6436     Document Type: Article

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