Interleukin-18 regulation of interferon γ production and cell proliferation as shown in interleukin-1β-converting enzyme (Caspase-1)- deficient mice

Blood

Volumn 91, Issue 6, 1998, Pages 2118-2125

  Fantuzzi, Giamila ^b   Puren, Adrian J ^b   Harding, Matthew W ^b   Livingston, David J ^b   Dinarello, Charles A ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 18; INTERLEUKIN 1BETA CONVERTING ENZYME; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; ZYMOSAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; IMMUNOMODULATION; INTERFERON INDUCTION; LYMPH NODE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL;

EID: 0032521457     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.6.2118.2118_2118_2125     Document Type: Article

References (31)

1. Okamura H, Nagata K, Komatsu T, Tanimoto T, Nukata Y, Tanabe F, Akita K, Torigoe K, Okura T, Fukuda S, Kurimoto M: A novel costimulatory factor for gamma interferon induction found in the livers of mice causes endotoxic shock. Infect Immun 63:3966, 1995
2. Okamura H, Tsutsui H, Komatsu T, Yutsudo M, Hakura A, Tanimoto T, Torigoe K, Okura T, Nukada Y, Hattori K, Akita K, Namba M, Tanabe F, Konishi K, Fukuda S, Kurimoto M: Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 378:88, 1995
3. Ushio S, Namba M, Okura T, Hattori K, Nukada Y, Akita K, Tanabe F, Konishi K, Micallef M, Fujii M, Torigoe K, Tanimoto T, Fukuda S, Ikeda M, Okamura H, Kurimoto M: Cloning of the cDNA for human IFN-γ-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J Immunol 156:4274, 1996
4. Rothe H, Jenkins NA, Copeland NG, Kolb H: Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2. J Clin Invest 99:469, 1997
5. Micallef MJ, Ohtsuki T, Kohno K, Tanabe F, Ushio S, Namba M, Tanimoto T, Torigoe K, Fujii M, Ikeda M, Fukuda S, Kurimoto M: Interferon-γ-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: Synergism with interleukin-12 for interferon-γ production. Eur J Immunol 26:1647, 1996
6. Tsutsui H, Nakanishi K, Matsui K, Higasino K, Okamura H, Miyazawa Y, Kaneda K: IFN-γ-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones. J Immunol 157:3967, 1996
7. Bazan JF, Timans JC, Kastelein RA: A newly defined interleukin-1? Nature 379:591, 1996
8. Gu Y, Kuida K, Tsutsui H, Ku G, Hsiao K, Fleming MA, Hayashi N, Higashino K, Okamura H, Nakanishi K, Kurimoto M, Tanimoto T, Flavell RA, Sato V, Harding MW, Livingston DJ, Su MS-S: Activation of interferon-γ inducing factor mediated by interleukin-1β converting enzyme. Science 275:206, 1997
9. Ghayur T, Banerjee S, Hugunin M, Butler D, Herzog L, Carter A, Quintal L, Sekut L, Talanian R, Paskind M, Wong W, Kamen R, Tracey D, Allen H: Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN-γ production. Nature 386:619, 1997
10. Liu Y, Janeway CA: Interferon gamma plays a critical role in induced cell death of effector T cell: A possible third mechanism of self-tolerance. J Exp Med 172:1735, 1990
11. Gajewski TF, Fitch FW: Anti-proliferative effects of IFNγ in immune regulation. I. IFNγ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J Immunol 140:4245, 1988
12. Kuida K, Lippke JA, Ku G, Harding MW, Livingston DJ, Su MS-S, Flavell RA: Altered cytokine export and apoptosis in mice deficient in interleukin-1β converting enzyme. Science 267:2000, 1995
13. Zheng H, Fletcher D, Kozak W, Jiang M, Hofmann K, Conn CA, Soszynski D, Grabiec C, Trumbauer ME, Shaw A, Kostura MJ, Stevens K, Rosen H, North RJ, Chen HY, Tocci MJ, Kluger MJ, Van der Ploeg LHT: Resistance to fever induction and impaired acute-phase response in interleukin-1β deficient mice. Immunity 3:9, 1995
14. Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W: Current Protocols in Immunology. Vol 1. In Vitro Assays for Mouse Lymphocyte Function. New York, NY, John Wiley & Sons, 1992
15. Goodwin CJ, Holt SJ, Downes S, Marshall NJ: Microculture tetrazolium assays: A comparison between two new tetrazolium salts, XTT and MTS. J Immunol Methods 179:95, 1995
16. Shapiro L, Dinarello CA: Hyperosmotic stress as a stimulant for proinflammatory cytokine production. Exp Cell Res 231, 1997
17. Trinchieri G, Gerosa F: Immunoregulation by interleukin-12. J Leukoc Biol 59:505, 1996
18. Mastroeni P, Harrison JA, Chabalgoity JA, Hormaeche CE: Effect of interleukin 12 neutralization on host resistance and gamma interferon production in mouse typhoid. Infect Immun 64:189, 1996
19. Fantuzzi G, Ku G, Harding MW, Livingston DJ, Kuida K, Flavell RA, Dinarello CA: Response to local inflammation of IL-1β converting enzyme-deficient mice. J Immunol 158:1818, 1997
20. Heinzel FP, Rerko RM, Ling P, Hakimi J, Schoenhaut DS: Interleukin 12 is produced in vivo during endotoxemia and stimulates synthesis of gamma interferon. Infect Immun 62:4244, 1994
21. Maehara N, Ho M: Cellular origin of interferon induced by bacterial lipopolysaccharide. Infect Immun 15:78, 1977
22. Salkowski CA, Detore GR, Vogel SN: Lipopolysaccharide and monophosphoryl lipid A differentially regulate interleukin-12, gamma interferon, and interleukin-10 mRNA production in murine macrophages. Infect Immun 65:3239, 1997
23. Ascher O, Apte RN, Pluznik OH: Generation of lipopolysaccharide-induced interferon in spleen cell cultures. I. Genetic analysis and cellular requirements. Immunogenetics 12:117, 1981
24. Billiau A: Interferon-γ: Biology and role in pathogenesis. Adv Immunol 62:61, 1996
25. Heinzel FP, Hujer AM, Ahmed FN, Rerko RM: In vivo production and function of IL-12 p40 homodimers. J Immunol 158:4381, 1997
26. Dalton DK, Pitts-Meek S, Keshav S, Figari IS, Bradley A, Stewart TA: Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science 259:1739, 1993
27. Norman J, Yang J, Fink G, Carter G, Ku G, Denham W, Livingston D: Severity and mortality of experimental pancreatitis are dependent on interleukin-1 converting enzyme (ICE). J Interferon Cytokine Res 17:113, 1997
28. Ku G, Faust T, Lauffer LL, Livingtson DJ, Harding MW: Interleukin-1β converting enzyme inhibition blocks progression of type II collagen-induced arthritis in mice. Cytokine 8:377, 1996
29. Hara H, Friedlander RM, Gagliardini V, Ayata C, Fink K, Huang Z, Shimizu-Sasamata M, Yuan J, Moskowitz MA: Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. Proc Natl Acad Sci USA 94:2007, 1997
30. Friedlander RM, Brown RH, Gagliardini V, Wang J, Yuan J: Inhibition of ICE slows ALS in mice. Nature 388:31, 1997
31. Li P, Allen H, Banerjee S, Franklin S, Herzog L, Jonhston C, McDowell J, Paskind M, Rodman L, Salfeld J, Towne E, Tracey D, Warwell S, Wei F-Y, Wong W, Kamen R, Seshadri T: Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. Cell 80:401, 1995