Differential upregulation of interleukin-18 receptor α chain between CD4+ and CD8+ T cells during acute graft-versus-host disease in mice

Journal of Interferon and Cytokine Research

Volumn 24, Issue 5, 2004, Pages 291-296

  Itoi, Hisayuki ^a   Fujimori, Yoshihiro ^a   Tsutsui, Hiroko ^a,b   Matsui, Kiyoshi ^a,b   Hada, Toshikazu ^a   Kakishita, Eizo ^a   Okamura, Haruki ^a,b   Kara, Hiroshi ^a   Nakanishi, Kenji ^a,b  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 18 RECEPTOR;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; CELL STIMULATION; CELL TRANSFER; CONTROLLED STUDY; DISEASE COURSE; EXPERIMENTAL MODEL; FEMALE; GRAFT VERSUS HOST REACTION; IN VITRO STUDY; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; UPREGULATION;

ACUTE DISEASE; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL TRANSPLANTATION; FEMALE; GENE EXPRESSION REGULATION; GRAFT VS HOST DISEASE; INTERLEUKIN-12; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; MICE; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-18; SPLEEN; TH1 CELLS; TH2 CELLS; TRANSPLANTATION CHIMERA; UP-REGULATION;

ANIMALIA; MURINAE;

EID: 2442557879     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999004323065075     Document Type: Article

References (31)

1. OKAMURA, H., TSUTSUI, H., KOMATSU, T., YUTSUDO, M., HAKURA, A., TANIMOTO, T., TORIGOE, K., OKURA, T., NUKADA, Y., HATTORI, K., AKITA, K., NAMBA, M., TANABE, F., KONISHI, K., FUKUDA, S., and KURIMOTO, M. (1995). Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 378, 88-91.
2. TSUTSUI, H., MATSUI, K., OKAMURA, H., and NAKANISHI, K. (2000). Pathophysiological roles of interleukin-18 for inflammatory liver diseases. Immunol Rev. 174, 192-209.
3. DINARELLO, C.A. (2000). Interleukin-18, a proinflammatory cytokine. Eur. Cytokine Netw. 11, 483-486.
4. NAKANISHI, K., YOSHIMOTO, Y., TSUTSUI, H., and OKAMURA, H. (2001). Interleukin-18 regulates both Th1 and Th2 responses. Annu. Rev. Immunol. 19, 423-474.
5. HYODO, Y., MATSUI, K., HAYASHI, N., TSUTSUI, H., KASHIWAMURA, S.-I., YAMAUCHI, H., HIROISHI, K., TAKEDA, K., TAGAWA, Y., IWAKURA, Y., KAYAGAKI, N., KURIMOTO, M., OKAMURA, H., HADA, T., YAGITA, H., AKIRA, S., NAKANISHI, K., and HIGASHINO, K. (1999). IL-18 up-regulates perforin-mediated NK activity without increasing perform messenger RNA expression by binding to constitutively expressed IL-18 receptor. J. Immunol. 162, 1662-1668.
6. TSUTSUI, H., NAKANISHI, K., MATSUI, K., HIGASHINO, K., OKAMURA, H., MIYAZAWA, Y., and KANEDA, K. (1996). Interferon-γ-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones. J. Immunol. 157, 3967-3973.
7. + effector T cells is differentially regulated by IL-18 and IL-12. J. Immunol. 162, 3202-3211.
8. + cytotoxic T lymphocytes by interleukin-18. Jpn. J. Cancer Res. 89, 1041-1046.
9. HOSHINO, K., TSUTSUI, H., KAWAI, T., TAKEDA, K., NAKANISHI, K., TAKEDA, Y., and AKIRA, S. (1999). Generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor. J. Immunol. 162, 5041-5044.
10. DEBETS, R., TIMANS, J.C., CHURAKOWA, T., ZURAWSKI, S., DE WAAL MALEFYT, R., MOORE, K.W., ABRAMS, J.S., O'GARRA, A., BAZAN, J.F., and KASTELEIN, R.A. (2000). IL-18 receptors, their role in ligand binding and function: anti-IL-1RAcPL antibody, a potent antagonist of IL-18. J. Immunol. 165, 4950-4956.
11. SEKI, E., TSUTSUI, H., TSUJI, N.M., HAYASHI, N., ADACHI, K., NAKANO, H., FUTATSUGI-YUMIKURA, S., TAKEUCHI, O., HOSHINO, K., AKIRA, S., FUJIMOTO, J., and NAKANISHI, K. (2002). Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice. J. Immunol. 169, 3863-3868.
12. NEIGHBORS, M., XU, X., BARRAT, F., RUULS, S.R., CHURAKOVA, T., DEBETS, R., BAZAN, J.F., KASTELEIN, R.A., ABRAMS, J.S., and O'GARRA, A. (2001). A critical role for interleukin-18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on interferon γ production. J. Exp. Med. 194, 343-354.
13. YOSHIMOTO, T., TAKEDA, K., TANAKA, T., OHKUSU, K., KASHIWAMURA, S., OKAMURA, H., AKIRA, S., and NAKANISHI, K. (1998). IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-γ production. J. Immunol. 161, 3400-3407.
14. AHN, H.J., MARUO, S., TOMURA, M., HAMAOKA, T., NAKANISHI, K., CLARK, S., KURIMOTO, M., OKAMURA, H., and FUJIWARA, H. (1997). A mechanism underlying synergy between IL-12 and IFN-γ-inducing factor in enhanced production of IFN-γ. J. Immunol. 159, 2125-2131.
15. ROBINSON, D., SHIBUYA, K., MUI, A., ZONIN, F., MURPHY, E., SANA, T., HARTLEY, S.B., MENON, S., KASTELEIN, R., BAZAN, F., and O'GARRA, A. (1997). IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NF-κB. Immunity 7, 571-581.
16. + T cells during T helper (Th) 1/Th2 differentiation: critical downregulatory role of IL-4. J. Exp. Med. 194, 143-153.
17. FUJIMORI, Y., YOSHIMOTO, T., MATSUI, K., TSUTSUI, H., OKAMOTO, T., KASHIWAMURA, S., HADA, T., OKAMURA, H., KAKISHITA, E., HARA, H., and NAKANISHI, K. (2002). Increased expression of interleukin 18 receptor on T lymphocytes in patients with acute graft-versus-host disease after allogeneic bone marrow transplantation. J. Interferon Cytokine Res. 22, 751-754.
18. KRENGER, W., HILL, G.R., and FERRARA, J.L.M. (1997). Cytokine cascades in acute graft-versus-host disease. Transplantation 64, 553-558.
19. + T cells. J. Immunol. 155, 2396-2406.
20. WILLIAMSON, E., GARSIDE, P., BRADLEY, J.A., and MOWAT, A.M. (1996). IL-12 is a central mediator of acute graft-versus-host disease in mice. J. Immunol. 157, 689-699.
21. HAKIM, F.T., SHARROW, S.O., PAYNE, S., and SHEARER, G.M. (1991). Repopulation of host lymphohematopoietic systems by donor cells during graft-versus-host reaction in unirradiated adult F1 mice injected with parental lymphocytes. J. Immunol. 146, 2108-2115.
22. + T cells requires CD154 expression by Th cells in acute graft-versus-host disease. J. Immunol. 162, 4373-4376.
23. + T cell activation and IFN-γ production. J. Immunol. 161, 2848-2855.
24. FUJOMORI, Y., TAKATSUKA, H., TAKEMOTO, Y., HARA, H., OKAMURA, H., NAKANISHI, K., and KAKISHITA, E. (2000). Elevated interleukin (IL)-18 levels during acute graft-versus-host disease after allogeneic bone marrow transplantation. Br. J. Haematol. 109, 652-657.
25. NAKAMURA, H., KOMATSU, K., AYAKI, M., KAWAMOTO, S., MURAKAMI, M., UOSHIMA, N., YAGI, T., HASEGAWA, T., YASUMI, M., KARASUNO, T., TESHIMA, H., HIRAOKA, A., and MASAOKA, T. (2000). Serum levels of soluble IL-2 receptor, IL-12, IL-18, and IFN-γ in patients with acute graft-versus-host disease after allogeneic bone marrow transplantation. J. Allergy Clin. Immunol. 106, S45-50.
26. ITOI, H., FUJIMORI, Y., TSUTSUI, H., MATSUI, K., FUTATSUGI, S., OKAMURA, H., HARA, H., HADA, T., KAKISHITA, E., and NAKANISHI, K. (2001). Fas ligand-induced caspase-1-dependent accumulation of interleukin-18 in mice with acute graft-versus-host disease. Blood 98, 235-237.
27. MAGRAM, J., CONNAUGHTON, S.E., WARRIER, R.R., CARVAIAL, D.M., WU, C.Y., FERRANTE, I., STEWART, C., SARMIENTO, U., FAHERTY, D.A., and GATELY, M.K. (1996). IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses. Immunity 4, 471-481.
28. XU, D., CHAN, W.L., LEUNG, B.P., HUNTER, D., SCHULZ, K., CARTER, R.W., McINNES, I.E., ROBINSON, I.H., and LIEW, F.Y. (1998). Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells. J. Exp. Med. 188, 1485-1492.
29. FREUDENBERG, M.A., MERLIN, T., KALIS, C., CHVATCHKO, Y., STUBIG, H., and GALANOS, C. (2002). A murine, IL-12-independent pathway of IFN-γ induction by gram-negative bacteria based on Stat4 activation by type I IFN and IL-18 signaling. J. Immunol. 169, 1665-1668.
30. SHLOMCHIK, W.D., COUZENS, M.S., TANG, C.B., McNIFF, J., ROBERT, M.E., LIU, J., SHLOMCHIK, M.J., and EMERSON, S.G. (1999). Prevention of graft-versus-host disease by inactivation of host antigen-presenting cells. Science 285, 412-415.
31. SHIMODA, K., TSUTSUI, H., AOKI, K., KATO, K., MATSUDA, T., NUMATA, A., TAKASE, K., YAMAMOTO, T., NUKINA, H., HOSHINO, T., ASANO, Y., GONDO, H., OKAMURA, T., OKAMURA, S., NAKAYAMA, D., NAKANISHI, K., NIHO, Y., and HARADA, M. (2002). Partial impairment of interleukin-12 (IL-12) and IL-18 signaling in Tyk2-deficient mice. Blood 99, 2094-2099.