In vivo administration of IL-18 can induce IgE production through Th2 cytokine induction and up-regulation of CD40 ligand (CD154) expression on CD4+ T cells

European Journal of Immunology

Volumn 30, Issue 7, 2000, Pages 1998-2006

  Hoshino, Tomoaki ^a,c   Yagita, Hideo ^b   Ortaldo, John R ^a   Wiltrout, Robert H ^a   Young, Howard A ^a  

^a NCI FCRDC   (United States)

^b JUNTENDO UNIVERSITY   (Japan)

^c KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CD154; CD4+ T cell; IgE; IL 18; Th2 cell

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN GP 39; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA; MONOCLONAL ANTIBODY CD3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNOGLOBULIN BLOOD LEVEL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TH2 CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS; ANTIGENS, CD3; ANTIGENS, CD4; ANTIGENS, CD8; ANTIGENS, SURFACE; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; FEMALE; HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-10; INTERLEUKIN-13; INTERLEUKIN-18; INTERLEUKIN-2; INTERLEUKIN-4; LECTINS, C-TYPE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEINS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TH2 CELLS; UP-REGULATION;

EID: 0033949150     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200007)30:7<1998::AID-IMMU1998>3.0.CO;2-U     Document Type: Article

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