ATP acts as an agonist to promote stimulus-induced secretion of IL-1β and IL-18 in human blood

Journal of Immunology

Volumn 165, Issue 8, 2000, Pages 4615-4623

  Perregaux, D G ^a   McNiff, P ^a   Laliberte, R ^a   Conklyn, M ^a   Gabel, C A ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOKINE; INTERLEUKIN 18; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NIGERICIN; PURINE P2X RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

AGONIST; ARTICLE; BLOOD; CELL ACTIVATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; HUMAN; HUMAN CELL; LEUKOCYTE; MALE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0034667943     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.8.4615     Document Type: Article

References (63)

1. Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory proteins and lectins
2. 2-terminal kinase and p38 MAPK signal pathways in rat renal mesangial cells
3. Effects of culture conditions and exposure to catobolic stimluators (IL-1 and retinoic acid) on the expression of matrix metalloproteinases (MMPs) and disintegrin metalloproteinases (ADAMs) by articular cartilage chondrocytes
4. Biologic basis for interleukin-1 in disease
5. Cytokine inter-relationships and their association with disease activity in arthritis
6. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis
7. Interleukin 1 receptor antagonist (IL-1RA) is an acute-phase protein
8. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA
9. Cloning sequence and expression of two distinct human interleukin-1 complementary DNAs
10. The interleukin-1 receptor binds the human interleukin-1 α precursor but not the interleukin-1β precursor
11. Involvement of a calpain-like protease in the processing of the murine interleukin I α precursor
12. Molecular cloning of the interleukin-1β converting enzyme
13. A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes
14. Activation of interferon-γ inducing factor mediated by interleukin-1β converting enzyme
15. Cloning of the cDNA for human IFN-γ-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein
16. Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane
17. Interleukin 1-β is localized in the cytoplasmic ground substance but is largely absent from the Golgi apparatus and plasma membrane of stimulated monocytes
18. Interleukin-1 is processed and released during apoptosis
19. Release of IL-1 from mononuclear phagocytes
20. IL-1β maturation: Evidence that mature cytokine formation can be induced specifically by nigericin
21. Human monocyte interleukin-1β posttranslational processing
22. Effects of Escherichia coli hemolysin on human monocytes
23. Tenidap and other anion transport inhibitors disrupt cytolytic T lymphocyte-mediated IL-1β post-translational processing
24. Tenidap modulates cytoplasmic pH and inhibits anion transport in vitro. II. Inhibition of JL-1β production from ATP-treated monocytes and macrophages
25. Extracellular ATP triggers IL-1β release by activating the purinergic P2Z receptor of human macrophages
26. Pharmacological characterization of ATP- and LPS-induced IL-1β release in human monocytes
27. 7)
28. The permeabilizing ATP receptor
29. 7 (P2Z) receptor in CHO-Kl cells
30. Extracellular ATP induces a large nonselective conductance in macrophage plasma membranes
31. 4- permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes
32. 7 channel
33. The P2Z purinoceptor: An intriguing role in immunity, inflammation and cell death
34. Post-translational processing of murine IL-1: Evidence that ATP-induced release of IL-1α and IL-1β occurs via a similar mechanism
35. 7 receptor
36. Purinergic modulation of interleukin-1β release from microglial cells stimulated with bacterial endotoxin
37. ATP induces the release of IL-1 from LPS-primed cells in vivo
38. Potassium-inhibited processing of IL-1β in human monocytes
39. Human monocyte ATP-induced IL-1β posttranslational processing is a dynamic process dependent on in vitro growth conditions
40. Lipopolysaccharide-induced cytokine production in peripheral blood mononuclear cells: Intracellular localization of tumor necrosis factor α and interleukin 1β detected with three-color immunofluorescence technique
41. Spontaneous release of angiotensin converting enzyme and interleukin 1β from peripheral blood monocytes from patients with rheumatoid arthritis under serum-free condition
42. Cells with dendritic morphology and bright interleukin-1α staining circulate in the blood of patients with rheumatoid arthritis
43. Secretion of TNF from a rat mast cell line is a brefeldin A-sensitive and a calcium/protein kinase C-regulated process
44. Evaluation of the Cell-Dyn 3000 differential
45. Comparative accessory cell function of human peripheral blood dendritic cells and monocytes
46. Changes in endotoxin-induced cytokine production by whole blood after in vivo exposure of normal humans to endotoxin
47. Transcriptional regulation of the human prointerleukin 1β gene
48. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist
49. Human monocyte production of interleukin-1: Parameters of the induction of interleukin-1 secretion by lipopolysaccharides
50. Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1β are differentially regulated in human blood mononuclear cells and mouse spleen cells
51. Sandwich ELISA formats designed to detect 17-kDa IL-1β significantly underestimate 35-kDa IL-1β
52. P2Z adenosine triphosphate receptor activity in cultured human monocyte-derived macrophages
53. The purinergic P2Z receptor of human macrophage cells
54. 7 nucleotide receptor and associated phospholipase D activity by lipopolysaccharide and IFN-γ in the human THP-1 monocytic cell line
55. 7 nucleotide receptor: High selectivity for the human versus rat receptor homologues
56. 7 purinergic receptor stimulation activate a common cytolytic pore
57. Murine T-lymphocytes modulate activity of an ATP-activated P2Z-type purinoceptor during differentiation
58. Extracellular adenosine triphosphate increases cation permeability of chronic lymphocytic leukemic lymphocytes
59. An ATP-activated channel is involved in mitogenic stimulation of human T-lymphocytes
60. 7 channel
61. + uptake: Inhibition of fluxes by suramin
62. Gender differences in IL-1α, IL-1β, and IL-1 receptor antagonist secretion from mononuclear cells and uninary excretion
63. Dissociation of IL-1β synthesis and secretion in human blood monocytes stimulated with bacterial cell wall products