P2X7 receptor modulation of β-amyloid- and LPS-induced cytokine secretion from human macrophages and microglia

Journal of Neuroimmunology

Volumn 147, Issue 1-2, 2004, Pages 56-61

  Rampe, David ^a   Wang, Lin ^a   Ringheim, Garth E ^a  

^a SANOFI   (France)

Author keywords

Alzheimer's disease; Inflammation; Macrophages; Microglia; P2X7; Amyloid

Indexed keywords

2',3' DIALDEHYDE ATP; 2',3' O (4 BENZOYLBENZOYL)ADENOSINE 5' TRIPHOSPHATE; 2',3'-DIALDEHYDE ATP; 3' O (4 BENZOYL)BENZOYLADENOSINE 5' TRIPHOSPHATE; 3'-O-(4-BENZOYL)BENZOYLADENOSINE 5'-TRIPHOSPHATE; ADENOSINE 5' TRIPHOSPHATE 2',3' ACYCLIC DIALCOHOL; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); CYTOKINE; DRUG DERIVATIVE; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PEPTIDE FRAGMENT; PURINE P2 RECEPTOR; PURINE P2X7 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANALYSIS OF VARIANCE; CELL ACTIVATION; CELL CULTURE; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; DRUG EFFECT; DRUG INTERACTION; DRUG POTENTIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EVALUATION; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; MACROPHAGE; METABOLISM; MICROGLIA; NEUROIMMUNOLOGY; OXIDATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN INDUCTION;

EID: 1642493590     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2003.10.014     Document Type: Conference Paper

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