Antinociceptive effect of a new P2Z/P2X7 antagonist, oxidized ATP, in arthritic rats

Neuroscience Letters

Volumn 327, Issue 2, 2002, Pages 87-90

  Dell'Antonio, Giacomo ^a   Quattrini, Angelo ^a   Dal Cin, Elena ^a   Fulgenzi, Alessandro ^b   Ferrero, Maria Elena ^b  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b CNR   (Italy)

Author keywords

Arthritis; Inflammation; Oxidized adenosine triphosphate; P2X7 receptor; Pain; Rat

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; DICLOFENAC; FREUND ADJUVANT; PURINE P2X RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; INFLAMMATION; MALE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; AFFINITY LABELS; ANIMALS; ARTHRITIS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; MALE; NOCICEPTORS; PAIN; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2;

EID: 0037135302     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)00385-3     Document Type: Article

References (20)

1. Perineural defect and peripheral opioid analgesia in inflammation
2. Acute nociception mediated by hindpaw P2X receptor activation in the rat
3. Overview. Purinergic mechanisms
4. A P2X purinoceptor expressed by a subset of sensory neurons
5. P2X receptor-mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint
6. ATP receptor-mediated synaptic currents in the central nervous system
7. ATP mediates fast synaptic transmission in mammalian neurons
8. Antinociceptive effects of intracerebroventricularly administered P2 purinoceptor agonists in the rat
9. Bradykinin system
10. The effects of inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat
11. Painful connection for ATP
12. Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons
13. Pain control in inflammation governed by selectins
14. 2z receptor
15. Peripheral adenosine 5′-triphosphate enhances nociception in the formalin test via activation of a purinergic p2X receptor
16. 2x receptor (P2X7)
17. Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice
18. 2x receptor for extracellular ATP
19. Vasodilator axon reflexes
20. Ethical guidelines for investigations of experimental pain in conscious animals