Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice

Journal of Experimental Medicine

Volumn 189, Issue 7, 1999, Pages 1129-1138

  Kanakaraj, Palanisamy ^a   Ngo, Karen ^a   Wu, Ying ^a   Angulo, Ana ^c   Ghazal, Peter ^c   Harris, Crafford A ^b   Siekierka, John J ^b   Peterson, Per A ^b   Fung Leung, Wai Ping ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^b R W JOHNSON PHARMACEUTICAL RES I   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

C Jun NH2 terminal kinase; Inhibitor of nuclear factor B; Interferon ; Murine cytomegalovirus; Nuclear factor B

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 18; LIPOPOLYSACCHARIDE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL INTERACTION; CELL MEDIATED CYTOTOXICITY; CELLULAR IMMUNITY; CYTOMEGALOVIRUS; ENZYME DEFICIENCY; HELPER CELL; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; KILLER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPIONIBACTERIUM; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIFFERENTIATION; CELL DIVISION; CHIMERA; CROSSES, GENETIC; CYTOMEGALOVIRUS INFECTIONS; CYTOTOXICITY, IMMUNOLOGIC; DEPRESSION, CHEMICAL; ENZYME ACTIVATION; ENZYME INDUCTION; FEMALE; GENE EXPRESSION REGULATION; INTERFERON TYPE II; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-18; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-4; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KILLER CELLS, NATURAL; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PROPIONIBACTERIUM ACNES; PROTEIN KINASES; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-18; SIGNAL TRANSDUCTION; TH1 CELLS; TH2 CELLS;

EID: 0033526110     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.7.1129     Document Type: Article

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