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Volumn 115, Issue 1 SPEC. ISS., 2005, Pages 74-79

IL-18 binding protein fusion construct delays the development of diabetes in adoptive transfer and cyclophosphamide-induced diabetes in NOD mouse

Author keywords

Interleukin 18; NOD mouse; Type 1 diabetes mellitus

Indexed keywords

CYCLOPHOSPHAMIDE; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 18; INTERLEUKIN 18 BINDING PROTEIN;

EID: 18144390563     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clim.2004.11.007     Document Type: Conference Paper
Times cited : (35)

References (27)
  • 1
    • 0031871335 scopus 로고    scopus 로고
    • An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus
    • A. Rabinovitch An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus Diabetes Metab. Rev. 14 1998 129 151
    • (1998) Diabetes Metab. Rev. , vol.14 , pp. 129-151
    • Rabinovitch, A.1
  • 2
    • 0035668779 scopus 로고    scopus 로고
    • Choice of death- the signal-transduction of immune-mediated β-cell apoptosis
    • D.L. Eizirik, and T. Mandrup-Poulsen Choice of death- the signal-transduction of immune-mediated β-cell apoptosis Diabetologia 44 2001 2115 2133
    • (2001) Diabetologia , vol.44 , pp. 2115-2133
    • Eizirik, D.L.1    Mandrup-Poulsen, T.2
  • 3
    • 0032607876 scopus 로고    scopus 로고
    • IL-18: A TH1-inducing proinflammatory cytokine and new member of the IL-1 family
    • C.A. Dinarello IL-18: a TH1-inducing proinflammatory cytokine and new member of the IL-1 family J. Allergy Clin. Immunol. 103 1999 11 24
    • (1999) J. Allergy Clin. Immunol. , vol.103 , pp. 11-24
    • Dinarello, C.A.1
  • 4
    • 0036103112 scopus 로고    scopus 로고
    • Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: Blocking interleukin 18 attenuates intestinal damage
    • P.V. Sivakumar, G.M. Westrich, S. Kanaly, K. Garka, T.L. Born, J.M. Derry, and J.L. Viney Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage Gut 50 2002 812 820
    • (2002) Gut , vol.50 , pp. 812-820
    • Sivakumar, P.V.1    Westrich, G.M.2    Kanaly, S.3    Garka, K.4    Born, T.L.5    Derry, J.M.6    Viney, J.L.7
  • 7
    • 0036290511 scopus 로고    scopus 로고
    • Neutralizing antibodies to IL-18 ameliorate experimental autoimmune neuritis by counter regulation of autoreactive Th1 responses to peripheral myelin antigen
    • S. Yu, Z. Chen, E. Mix, S.-W. Zhu, B. Winblad, H.-G. Ljunggren, and J. Zhu Neutralizing antibodies to IL-18 ameliorate experimental autoimmune neuritis by counter regulation of autoreactive Th1 responses to peripheral myelin antigen J. Neuropathol. Exp. Neurol. 61 2002 614 622
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 614-622
    • Yu, S.1    Chen, Z.2    Mix, E.3    Zhu, S.-W.4    Winblad, B.5    Ljunggren, H.-G.6    Zhu, J.7
  • 10
    • 0035081444 scopus 로고    scopus 로고
    • Serum levels of the interferon-g-inducing cytokine interleukin-18 are increased in individuals at high risk of developing type 1 diabetes
    • F. Nicoletti, I. Conget, R. Di Marco, A.M. Speciale, R. Morìnigo, K. Bendtzen, and R. Gomis Serum levels of the interferon-g-inducing cytokine interleukin-18 are increased in individuals at high risk of developing type 1 diabetes Diabetologia 44 2001 309 311
    • (2001) Diabetologia , vol.44 , pp. 309-311
    • Nicoletti, F.1    Conget, I.2    Di Marco, R.3    Speciale, A.M.4    Morìnigo, R.5    Bendtzen, K.6    Gomis, R.7
  • 14
    • 0042977338 scopus 로고    scopus 로고
    • Essential pathogenic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycaemia and insulitis by a recombinant IL-18-binding protein: Fc construct
    • F. Nicoletti, R. Di Marco, G. Papaccio, I. Conget, R. Gomis, R. Bernardini, J.E. Sims, Y. Shoenfeld, and K. Bendtzen Essential pathogenic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycaemia and insulitis by a recombinant IL-18-binding protein: Fc construct Eur. J. Immunol. 33 2003 2278 2286
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2278-2286
    • Nicoletti, F.1    Di Marco, R.2    Papaccio, G.3    Conget, I.4    Gomis, R.5    Bernardini, R.6    Sims, J.E.7    Shoenfeld, Y.8    Bendtzen, K.9
  • 15
    • 0242492516 scopus 로고    scopus 로고
    • Lack of mediators of innate immunity attenuate the development of autoimmune diabetes in mice
    • M.L. Lukic, E. Mensah-Brown, X. Wei, A. Shanin, and F. Liew Lack of mediators of innate immunity attenuate the development of autoimmune diabetes in mice J. Autoimmun. 21 2003 239 246
    • (2003) J. Autoimmun. , vol.21 , pp. 239-246
    • Lukic, M.L.1    Mensah-Brown, E.2    Wei, X.3    Shanin, A.4    Liew, F.5
  • 16
    • 0036244573 scopus 로고    scopus 로고
    • Functional IL-18 is produced by primary pancreatic mouse islet and NIT-1β cells and participates in the progression towards destructive insulitis
    • S. Frigerio, G.A. Hollander, and U. Zumsteg Functional IL-18 is produced by primary pancreatic mouse islet and NIT-1β cells and participates in the progression towards destructive insulitis Horm. Res. 57 2002 94 104
    • (2002) Horm. Res. , vol.57 , pp. 94-104
    • Frigerio, S.1    Hollander, G.A.2    Zumsteg, U.3
  • 17
    • 0030777296 scopus 로고    scopus 로고
    • Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2
    • J. Rothe, N.A. Jenkins, N.G. Copeland, and H. Kolb Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2 J. Clin. Invest. 99 1997 469 474
    • (1997) J. Clin. Invest. , vol.99 , pp. 469-474
    • Rothe, J.1    Jenkins, N.A.2    Copeland, N.G.3    Kolb, H.4
  • 18
    • 0033178614 scopus 로고    scopus 로고
    • IL-18 inhibits diabetes development in non obese diabetic mice by counterregulation of Th1-dependent destructive insulitis
    • H. Rothe, A. Hausmann, K. Casteels, H. Okamura, M. Kurimoto, V. Bukart, C. Mathieu, and H. Kolb IL-18 inhibits diabetes development in non obese diabetic mice by counterregulation of Th1-dependent destructive insulitis J. Immunol. 163 1999 1230 1236
    • (1999) J. Immunol. , vol.163 , pp. 1230-1236
    • Rothe, H.1    Hausmann, A.2    Casteels, K.3    Okamura, H.4    Kurimoto, M.5    Bukart, V.6    Mathieu, C.7    Kolb, H.8
  • 21
    • 0031023298 scopus 로고    scopus 로고
    • Prevention of spontaneous autoimmune diabetes in diabetes-prone BB rats by prophylactic treatment with antirat interferon-g antibody
    • F. Nicoletti, P. Zaccone, R. Di Marco, M. Lunetta, G. Magro, S. Grasso, P. Meroni, and G. Garotta Prevention of spontaneous autoimmune diabetes in diabetes-prone BB rats by prophylactic treatment with antirat interferon-g antibody Endocrinology 138 1997 281 288
    • (1997) Endocrinology , vol.138 , pp. 281-288
    • Nicoletti, F.1    Zaccone, P.2    Di Marco, R.3    Lunetta, M.4    Magro, G.5    Grasso, S.6    Meroni, P.7    Garotta, G.8
  • 22
    • 0037106362 scopus 로고    scopus 로고
    • Nondepleting anti-CD4 and soluble interleukin-1 receptor prevent autoimmune destruction of syngeneic islet grafts in diabetic NOD mice
    • M. Drage, P. Zaccone, J.M. Phillips, F. Nicoletti, J. Dawson, J. Andrew Bradley, and A. Cooke Nondepleting anti-CD4 and soluble interleukin-1 receptor prevent autoimmune destruction of syngeneic islet grafts in diabetic NOD mice Transplantation 74 2002 611 619
    • (2002) Transplantation , vol.74 , pp. 611-619
    • Drage, M.1    Zaccone, P.2    Phillips, J.M.3    Nicoletti, F.4    Dawson, J.5    Andrew Bradley, J.6    Cooke, A.7
  • 24
    • 0038407295 scopus 로고    scopus 로고
    • Cellular and molecular changes accompanying the progression from insulitis to diabetes
    • I. Andre-Schmutz, C. Hindelang, C. Benoist, and D. Mathis Cellular and molecular changes accompanying the progression from insulitis to diabetes Eur. J. Immunol. 29 1999 245 255
    • (1999) Eur. J. Immunol. , vol.29 , pp. 245-255
    • Andre-Schmutz, I.1    Hindelang, C.2    Benoist, C.3    Mathis, D.4
  • 25
    • 0035036375 scopus 로고    scopus 로고
    • Disease resistant, NOD-related strains reveal checkpoints of immunoregulation in the pancreas
    • H. Rothe, Y. Ito, and H. Kolb Disease resistant, NOD-related strains reveal checkpoints of immunoregulation in the pancreas J. Mol. Med. 79 2001 187 190
    • (2001) J. Mol. Med. , vol.79 , pp. 187-190
    • Rothe, H.1    Ito, Y.2    Kolb, H.3
  • 26
    • 0035071329 scopus 로고    scopus 로고
    • Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu
    • K. Nakanishi, T. Yoshimoto, H. Tsutsui, and H. Okamura Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu Cytokine Growth Factor Rev. 12 2001 53 72
    • (2001) Cytokine Growth Factor Rev. , vol.12 , pp. 53-72
    • Nakanishi, K.1    Yoshimoto, T.2    Tsutsui, H.3    Okamura, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.