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Volumn 55, Issue 6, 2006, Pages 684-698

Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimens: Implications for survival

Author keywords

Cytokines; Pancreatic carcinoma; Tumor immunity

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

EID: 33644586895     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-005-0047-0     Document Type: Article
Times cited : (181)

References (64)
  • 2
    • 0036375050 scopus 로고    scopus 로고
    • Interleukin-1 - A major pleiotropic cytokine in tumor-host interactions
    • Apte RN, Voronov E (2002) Interleukin-1 - a major pleiotropic cytokine in tumor-host interactions. Semin Cancer Biol 12:277-290
    • (2002) Semin Cancer Biol , vol.12 , pp. 277-290
    • Apte, R.N.1    Voronov, E.2
  • 3
    • 0035020568 scopus 로고    scopus 로고
    • IL-6-like cytokines and cancer cachexia: Consequences of chronic inflammation
    • Barton BE (2001) IL-6-like cytokines and cancer cachexia: consequences of chronic inflammation. Immunol Res 23:41-58
    • (2001) Immunol Res , vol.23 , pp. 41-58
    • Barton, B.E.1
  • 5
    • 0032770957 scopus 로고    scopus 로고
    • Tumor-associated transforming growth factor-beta and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients
    • Bellone G, Turletti A, Artusio E, Mareschi K, Carbone A, Tibaudi D, Robecchi A, Emanuelli G, Rodeck U (1999) Tumor-associated transforming growth factor-beta and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients. Am J Pathol 155:537-547
    • (1999) Am J Pathol , vol.155 , pp. 537-547
    • Bellone, G.1    Turletti, A.2    Artusio, E.3    Mareschi, K.4    Carbone, A.5    Tibaudi, D.6    Robecchi, A.7    Emanuelli, G.8    Rodeck, U.9
  • 6
    • 0025853795 scopus 로고
    • Serum interleukin-6 levels correlate with disease status in patients with epithelial ovarian cancer
    • Berek JS, Chung C, Kaldi K, Watson JM, Knox RM, Martinez-Maza O (1991) Serum interleukin-6 levels correlate with disease status in patients with epithelial ovarian cancer. Am J Obstet Gynecol 164:1038-1042
    • (1991) Am J Obstet Gynecol , vol.164 , pp. 1038-1042
    • Berek, J.S.1    Chung, C.2    Kaldi, K.3    Watson, J.M.4    Knox, R.M.5    Martinez-Maza, O.6
  • 8
    • 0036125118 scopus 로고    scopus 로고
    • Association of elevated glial expression of interleukin-1beta with improved survival in patients with glioblastomas multiforme
    • Cuny E, Loiseau H, Penchet G, Ellie E, Arsaut J, Vital A, Vincendeau P, Demotes-Mainard J (2002) Association of elevated glial expression of interleukin-1beta with improved survival in patients with glioblastomas multiforme. J Neurosurg 96:294-301
    • (2002) J Neurosurg , vol.96 , pp. 294-301
    • Cuny, E.1    Loiseau, H.2    Penchet, G.3    Ellie, E.4    Arsaut, J.5    Vital, A.6    Vincendeau, P.7    Demotes-Mainard, J.8
  • 9
    • 0031831906 scopus 로고    scopus 로고
    • Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist
    • Dinarello CA (1998) Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int Rev Immunol 16:457-499
    • (1998) Int Rev Immunol , vol.16 , pp. 457-499
    • Dinarello, C.A.1
  • 10
    • 0032909752 scopus 로고    scopus 로고
    • Interleukin-18 and interleukin-1 beta: Two cytokine substrates for ICE (caspase-1)
    • Fantuzzi G, Dinarello CA (1999) Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1). J Clin Immunol 19:1-11
    • (1999) J Clin Immunol , vol.19 , pp. 1-11
    • Fantuzzi, G.1    Dinarello, C.A.2
  • 13
    • 0032404111 scopus 로고    scopus 로고
    • Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas
    • Goggins M, Shekher M, Turnacioglu K, Yeo CJ, Hruban RH, Kern SE (1998) Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas. Cancer Res 58:5329-5332
    • (1998) Cancer Res , vol.58 , pp. 5329-5332
    • Goggins, M.1    Shekher, M.2    Turnacioglu, K.3    Yeo, C.J.4    Hruban, R.H.5    Kern, S.E.6
  • 15
    • 0035886468 scopus 로고    scopus 로고
    • Preoperative serum interleukin-18 levels as a postoperative prognostic marker in patients with gastric carcinoma
    • Kawabata T, Ichikura T, Majima T, Seki S, Chochi K, Takayama E, Hiraide H, Mochizuki H (2001) Preoperative serum interleukin-18 levels as a postoperative prognostic marker in patients with gastric carcinoma. Cancer 92:2050-2055
    • (2001) Cancer , vol.92 , pp. 2050-2055
    • Kawabata, T.1    Ichikura, T.2    Majima, T.3    Seki, S.4    Chochi, K.5    Takayama, E.6    Hiraide, H.7    Mochizuki, H.8
  • 16
    • 1842430506 scopus 로고    scopus 로고
    • Development of immunotherapy for pancreatic cancer
    • Kawakami Y, Okada T, Akada M (2004) Development of immunotherapy for pancreatic cancer. Pancreas 28:320-325
    • (2004) Pancreas , vol.28 , pp. 320-325
    • Kawakami, Y.1    Okada, T.2    Akada, M.3
  • 21
    • 0029742706 scopus 로고    scopus 로고
    • Transforming growth factor-beta: A general review
    • Lawrence DA (1996) Transforming growth factor-beta: a general review. Eur Cytokine Netw 7:363-374
    • (1996) Eur Cytokine Netw , vol.7 , pp. 363-374
    • Lawrence, D.A.1
  • 23
    • 0037443760 scopus 로고    scopus 로고
    • IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis
    • Li A, Dubey S, Varney ML, Dave BJ, Singh RK (2003) IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J Immunol 170:3369-3376
    • (2003) J Immunol , vol.170 , pp. 3369-3376
    • Li, A.1    Dubey, S.2    Varney, M.L.3    Dave, B.J.4    Singh, R.K.5
  • 26
    • 0027396955 scopus 로고
    • Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression
    • Lu C, Kerbel RS (1993) Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression. J Cell Biol 120:1281-1288
    • (1993) J Cell Biol , vol.120 , pp. 1281-1288
    • Lu, C.1    Kerbel, R.S.2
  • 27
    • 4444366400 scopus 로고    scopus 로고
    • Molecular therapy in pancreatic adenocarcinoma
    • MacKenzie MJ (2004) Molecular therapy in pancreatic adenocarcinoma. Lancet Oncol 5:541-549
    • (2004) Lancet Oncol , vol.5 , pp. 541-549
    • MacKenzie, M.J.1
  • 28
    • 0029671316 scopus 로고    scopus 로고
    • TGF-beta contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice
    • Maeda H, Shiraishi A (1996) TGF-beta contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice. J Immunol 156:73-78
    • (1996) J Immunol , vol.156 , pp. 73-78
    • Maeda, H.1    Shiraishi, A.2
  • 31
    • 3042823539 scopus 로고    scopus 로고
    • Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer
    • Michalaki V, Syrigos K, Charles P, Waxman J (2004) Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer. Br J Cancer 90:2312-2316
    • (2004) Br J Cancer , vol.90 , pp. 2312-2316
    • Michalaki, V.1    Syrigos, K.2    Charles, P.3    Waxman, J.4
  • 32
    • 0037295701 scopus 로고    scopus 로고
    • Squamous cell carcinoma cells differentially stimulate NK cell effector functions: The role of IL-18
    • Moore MB, Kurago ZB, Fullenkamp CA, Lutz CT (2003) Squamous cell carcinoma cells differentially stimulate NK cell effector functions: the role of IL-18. Cancer Immunol Immunother 52:107-115
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 107-115
    • Moore, M.B.1    Kurago, Z.B.2    Fullenkamp, C.A.3    Lutz, C.T.4
  • 34
    • 0035071329 scopus 로고    scopus 로고
    • Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu
    • Nakanishi K, Yoshimoto T, Tsutsui H, Okamura H (2001) Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu. Cytokine Growth Factor Rev 12:53-72
    • (2001) Cytokine Growth Factor Rev , vol.12 , pp. 53-72
    • Nakanishi, K.1    Yoshimoto, T.2    Tsutsui, H.3    Okamura, H.4
  • 37
    • 0029038543 scopus 로고
    • Expression of leukemia inhibitory factor and interleukin-11 by human melanoma cell lines: LIF, IL-6, and IL-11 are not coregulated
    • Paglia D, Oran A, Lu C, Kerbel RS, Sauder DN, McKenzie RC (1995) Expression of leukemia inhibitory factor and interleukin-11 by human melanoma cell lines: LIF, IL-6, and IL-11 are not coregulated. J Interferon Cytokine Res 15:455-460
    • (1995) J Interferon Cytokine Res , vol.15 , pp. 455-460
    • Paglia, D.1    Oran, A.2    Lu, C.3    Kerbel, R.S.4    Sauder, D.N.5    McKenzie, R.C.6
  • 39
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • Pfaffl MW, Horgan GW, Dempfle L (2002) Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30:e36
    • (2002) Nucleic Acids Res , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 40
    • 0037435395 scopus 로고    scopus 로고
    • Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data
    • Ramakers C, Ruijter JM, Deprez RH, Moorman AF (2003) Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data. Neurosci Lett 339:62-66
    • (2003) Neurosci Lett , vol.339 , pp. 62-66
    • Ramakers, C.1    Ruijter, J.M.2    Deprez, R.H.3    Moorman, A.F.4
  • 41
    • 0002129975 scopus 로고    scopus 로고
    • Quantification on the LightCycler
    • Meuer S, Wittwer C, Nakagawara K (eds) Springer Press, Heidelberg
    • Rasmussen R (2001) Quantification on the LightCycler. In: Meuer S, Wittwer C, Nakagawara K (eds) Rapid Cycle Realtime PCR, Methods and Applications. Springer Press, Heidelberg, pp 21-34
    • (2001) Rapid Cycle Realtime PCR, Methods and Applications , pp. 21-34
    • Rasmussen, R.1
  • 42
    • 1442354134 scopus 로고    scopus 로고
    • Expression of IL-18 in patients with head and neck squamous cell carcinoma
    • Mannheim Alcohol Study Group
    • Riedel F, Adam S, Feick P, Haas S, Gotte K, Hormann K (2004) Mannheim Alcohol Study Group. Expression of IL-18 in patients with head and neck squamous cell carcinoma. Int J Mol Med 13:267-272
    • (2004) Int J Mol Med , vol.13 , pp. 267-272
    • Riedel, F.1    Adam, S.2    Feick, P.3    Haas, S.4    Gotte, K.5    Hormann, K.6
  • 43
    • 0034480072 scopus 로고    scopus 로고
    • An elevated serum level of transforming growth factor-beta 1 (TGF-beta 1) significantly correlated with lymph node metastasis and poor prognosis in patients with gastric carcinoma
    • Saito H, Tsujitani S, Oka S, Kondo A, Ikeguchi M, Maeta M, Kaibara N (2000) An elevated serum level of transforming growth factor-beta 1 (TGF-beta 1) significantly correlated with lymph node metastasis and poor prognosis in patients with gastric carcinoma. Anticancer Res 20:4489-4493
    • (2000) Anticancer Res , vol.20 , pp. 4489-4493
    • Saito, H.1    Tsujitani, S.2    Oka, S.3    Kondo, A.4    Ikeguchi, M.5    Maeta, M.6    Kaibara, N.7
  • 48
    • 0035839310 scopus 로고    scopus 로고
    • Interleukins-6 and -11 expression in primary breast cancer and subsequent development of bone metastases
    • Sotiriou C, Lacroix M, Lespagnard L, Larsimont D, Paesmans M, Body JJ (2001) Interleukins-6 and -11 expression in primary breast cancer and subsequent development of bone metastases. Cancer Lett 169:87-95
    • (2001) Cancer Lett , vol.169 , pp. 87-95
    • Sotiriou, C.1    Lacroix, M.2    Lespagnard, L.3    Larsimont, D.4    Paesmans, M.5    Body, J.J.6
  • 49
    • 1342322968 scopus 로고    scopus 로고
    • Serum levels of interleukin-18 and nitrite + nitrate in renal cell carcinoma patients with different tumor stage and grade
    • Sozen S, Coskun U, Sancak B, Bukan N, Gunel N, Tunc L, Bozkirli I (2004) Serum levels of interleukin-18 and nitrite + nitrate in renal cell carcinoma patients with different tumor stage and grade. Neoplasma 51:25-29
    • (2004) Neoplasma , vol.51 , pp. 25-29
    • Sozen, S.1    Coskun, U.2    Sancak, B.3    Bukan, N.4    Gunel, N.5    Tunc, L.6    Bozkirli, I.7
  • 50
    • 0742321750 scopus 로고    scopus 로고
    • Role of IL-13 in regulation of anti-tumor immunity and tumor growth
    • Terabe M, Park JM, Berzofsky JA (2004) Role of IL-13 in regulation of anti-tumor immunity and tumor growth. Cancer Immunol Immunother 53:79-85
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 79-85
    • Terabe, M.1    Park, J.M.2    Berzofsky, J.A.3
  • 52
    • 0042662912 scopus 로고    scopus 로고
    • IL-11-induced reduction of C/EBP transcription factor binding may contribute to the IL-12 downregulation in tumor-bearing mice
    • Torroella-Kouri M, Keith JC, Ivanova M, Lopez DM (2003) IL-11-induced reduction of C/EBP transcription factor binding may contribute to the IL-12 downregulation in tumor-bearing mice. Int J Oncol 22:439-448
    • (2003) Int J Oncol , vol.22 , pp. 439-448
    • Torroella-Kouri, M.1    Keith, J.C.2    Ivanova, M.3    Lopez, D.M.4
  • 53
    • 0030587817 scopus 로고    scopus 로고
    • Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production
    • Trepicchio WL, Bozza M, Pedneault G, Dorner AJ (1996) Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production. J Immunol 157:3627-3634
    • (1996) J Immunol , vol.157 , pp. 3627-3634
    • Trepicchio, W.L.1    Bozza, M.2    Pedneault, G.3    Dorner, A.J.4
  • 54
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri G (2003) Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 3:133-146
    • (2003) Nat Rev Immunol , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 56
    • 0028027039 scopus 로고
    • Serum levels of cytokines in patients with colorectal cancer: Possible involvement of interleukin-6 and interleukin-8 in hematogenous metastasis
    • Ueda T, Shimada E, Urakawa T (1994) Serum levels of cytokines in patients with colorectal cancer: possible involvement of interleukin-6 and interleukin-8 in hematogenous metastasis. J Gastroenterol 29:423-429
    • (1994) J Gastroenterol , vol.29 , pp. 423-429
    • Ueda, T.1    Shimada, E.2    Urakawa, T.3
  • 57
    • 0032522848 scopus 로고    scopus 로고
    • Human pancreatic adenocarcinomas express Fas and Fas ligand yet are resistant to Fas-mediated apoptosis
    • Ungefroren H, Voss M, Jansen M, Roeder C, Henne-Bruns D, Kremer B, Kalthoff H (1998) Human pancreatic adenocarcinomas express Fas and Fas ligand yet are resistant to Fas-mediated apoptosis. Cancer Res 58: 1741-1749
    • (1998) Cancer Res , vol.58 , pp. 1741-1749
    • Ungefroren, H.1    Voss, M.2    Jansen, M.3    Roeder, C.4    Henne-Bruns, D.5    Kremer, B.6    Kalthoff, H.7
  • 61
    • 0037140122 scopus 로고    scopus 로고
    • Expression of interleukin-18 in human ovarian carcinoma and normal ovarian epithelium: Evidence for defective processing in tumor cells
    • Wang ZY, Gaggero A, Rubartelli A, Rosso O, Miotti S, Mezzanzanica D, Canevari S, Ferrini S (2002) Expression of interleukin-18 in human ovarian carcinoma and normal ovarian epithelium: evidence for defective processing in tumor cells. Int J Cancer 98:873-878
    • (2002) Int J Cancer , vol.98 , pp. 873-878
    • Wang, Z.Y.1    Gaggero, A.2    Rubartelli, A.3    Rosso, O.4    Miotti, S.5    Mezzanzanica, D.6    Canevari, S.7    Ferrini, S.8
  • 63
    • 0032802779 scopus 로고    scopus 로고
    • Elevated serum levels of transforming growth factor beta1 in Epstein-Barr virus-associated nasopharyngeal carcinoma patients
    • Xu J, Menezes J, Prasad U, Ahmad A (1999) Elevated serum levels of transforming growth factor beta1 in Epstein-Barr virus-associated nasopharyngeal carcinoma patients. Int J Cancer 84:396-399
    • (1999) Int J Cancer , vol.84 , pp. 396-399
    • Xu, J.1    Menezes, J.2    Prasad, U.3    Ahmad, A.4
  • 64
    • 0037600776 scopus 로고    scopus 로고
    • Expression of IL-18 and its receptor in human leukemia cells
    • Zhang B, Ma XT, Zheng GG, Li G, Rao Q, Wu KF (2003) Expression of IL-18 and its receptor in human leukemia cells. Leuk Res 27:813-822
    • (2003) Leuk Res , vol.27 , pp. 813-822
    • Zhang, B.1    Ma, X.T.2    Zheng, G.G.3    Li, G.4    Rao, Q.5    Wu, K.F.6


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