IL-18 inhibits diabetes development in nonobese diabetic mice by counterregulation of Th1-dependent destructive insulitis

Journal of Immunology

Volumn 163, Issue 3, 1999, Pages 1230-1236

  Rothe, Helga ^a,b   Hausmann, Andreas ^a   Casteels, Kristina ^c   Okamura, Hakuri ^d   Kurimoto, Masashi ^e   Burkart, Volker ^a   Mathieu, Chantal ^c   Kolb, Hubert ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b INSTITUT FÜR DIABETESFORSCHUNG   (Germany)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d HYOGO COLLEGE OF MEDICINE   (Japan)

^e Fujisaki Institute   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1 DERIVATIVE; INTERLEUKIN 12; INTERLEUKIN 18; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIABETOGENESIS; DISEASE ASSOCIATION; DRUG SCREENING; FEMALE; HELPER CELL; IMMUNOREACTIVITY; IMMUNOREGULATION; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; MACROPHAGE; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME;

ANIMALS; CYTOKINES; DIABETES MELLITUS, TYPE 1; FEMALE; HYPOGLYCEMIC AGENTS; INJECTIONS; INTERLEUKIN-18; ISLETS OF LANGERHANS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED NOD; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PREDIABETIC STATE; RNA, MESSENGER; TH1 CELLS;

EID: 0033178614     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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