The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci

Genomics

Volumn 51, Issue 1, 1998, Pages 161-163

  Nolan, Kathleen F ^a   Greaves, David R ^a   Waldmann, Herman ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE;

ARTICLE; CHROMOSOME 11Q; GENE LOCUS; GENE MAPPING; GENETIC ANALYSIS; GENETIC LINKAGE; HUMAN; IMMUNOGENETICS; INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

EID: 0032126111     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1998.5336     Document Type: Article

References (5)

1. Matsuda Y., Imai T., Shiomi T., Saito T., Yamauchi M., Fukao T., Akao Y., Seki N., Ito H., Hori T. A. Comparative genome mapping of the ataxia-telangiectasia region in mouse, rat, and Syrian hamster. Genomics. 34:1996;347-352.
2. Pritchard L. E., Kawaguchi Y., Reed P. W., Copeman J. B., Davies J. L., Barnett A. H., Bain S. C., Todd J. A. Analysis of the CD3 gene region and type 1 diabetes: Application of fluorescence-based technology to linkage disequilibrium mapping. Hum. Mol. Genet. 4:1995;197-202.
3. Robinson D., Shibuya K., Mui A., Zonin F., Murphy E., Sana T., Hartley S. B., Menon S., Kastelein R., Bazan F., O'Garra A. IGIF does not drive Th1 development but synergizes with IL-12 for interferon-γ production and activates IRAK and NFκB. Immunity. 7:1997;571-581.
4. Rothe H., Jenkins N. A., Copeland N. G., Kolb H. Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located nearIdd2. J. Clin. Invest. 99:1997;469-474.
5. Vyse T. J., Todd J. A. Genetic analysis of autoimmune disease. Cell. 85:1996;311-318.