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Volumn 2, Issue 2, 2007, Pages 181-193

Cholesterol: From feeding to gene regulation

Author keywords

Cholesterol; HMG CoA reductase; Insig; LDLr; SCAP; SREBPs

Indexed keywords

ABC TRANSPORTER; CHOLESTEROL; CHYLOMICRON; GENE PRODUCT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; INSULIN INDUCED PROTEIN; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

EID: 38149142757     PISSN: 15558932     EISSN: 18653499     Source Type: Journal    
DOI: 10.1007/s12263-007-0049-y     Document Type: Review
Times cited : (43)

References (135)
  • 1
    • 0141591549 scopus 로고    scopus 로고
    • Cholesterol induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles
    • Adams CM, Goldstein JL, Brown MS (2003) Cholesterol induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles. Proc Natl Acad Sci USA 100:10647-10652
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10647-10652
    • Adams, C.M.1    Goldstein, J.L.2    Brown, M.S.3
  • 5
    • 0035423555 scopus 로고    scopus 로고
    • ER export: Public transportation by the COPII coach
    • Antonny B, Schekman R (2001) ER export: public transportation by the COPII coach. Curr Opin Cell Biol 13:438-443
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 438-443
    • Antonny, B.1    Schekman, R.2
  • 6
    • 0032489878 scopus 로고    scopus 로고
    • Cargo selection by the COPII budding machinery during export from the ER
    • Aridor M, Weissman J, Bannykh SI, Nuoffer C, Balch WE (1998) Cargo selection by the COPII budding machinery during export from the ER. J Cell Biol 141:61-70
    • (1998) J Cell Biol , vol.141 , pp. 61-70
    • Aridor, M.1    Weissman, J.2    Bannykh, S.I.3    Nuoffer, C.4    Balch, W.E.5
  • 7
    • 0034283596 scopus 로고    scopus 로고
    • Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes
    • Azzout-Marniche D, Becard D, Guichard C, Foretz M, Ferre P, Foufelle F (2000) Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes. Biochem J 350(Pt. 2):389-393
    • (2000) Biochem J , vol.350 , Issue.PART. 2 , pp. 389-393
    • Azzout-Marniche, D.1    Becard, D.2    Guichard, C.3    Foretz, M.4    Ferre, P.5    Foufelle, F.6
  • 8
    • 0036701908 scopus 로고    scopus 로고
    • COPII-dependent transport from the endoplasmic reticulum
    • Barlowe C (2002) COPII-dependent transport from the endoplasmic reticulum. Curr Opin Cell Biol 14:417-422
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 417-422
    • Barlowe, C.1
  • 9
    • 0037977708 scopus 로고    scopus 로고
    • Skeletal muscle sterol regulatory element binding protein-1c decreases with food deprivation and increases with feeding in rats
    • Bizeau ME, MacLean PS, Johnson GC, Wei Y (2003) Skeletal muscle sterol regulatory element binding protein-1c decreases with food deprivation and increases with feeding in rats. J Nutr 133:1787-1792
    • (2003) J Nutr , vol.133 , pp. 1787-1792
    • Bizeau, M.E.1    MacLean, P.S.2    Johnson, G.C.3    Wei, Y.4
  • 10
    • 18844408581 scopus 로고    scopus 로고
    • Age-related alteration in hepatic acyl-CoA: Cholesterol acyltransferase and its relation to LDL receptor and MAPK
    • Bose C, Bhuvaneswaran C, Udupa KB (2005) Age-related alteration in hepatic acyl-CoA: cholesterol acyltransferase and its relation to LDL receptor and MAPK. Mech Ageing Dev 126:740-751
    • (2005) Mech Ageing Dev , vol.126 , pp. 740-751
    • Bose, C.1    Bhuvaneswaran, C.2    Udupa, K.B.3
  • 11
    • 0032913411 scopus 로고    scopus 로고
    • Percent cholesterol absorption in normal women and men quantified with dual stable isotopic tracers and negative ion mass spectrometry
    • Bosner MS, Lange LG, Stenson WF, Ostlund RE Jr (1999) Percent cholesterol absorption in normal women and men quantified with dual stable isotopic tracers and negative ion mass spectrometry. J Lipid Res 40:302-308
    • (1999) J Lipid Res , vol.40 , pp. 302-308
    • Bosner, M.S.1    Lange, L.G.2    Stenson, W.F.3    Ostlund Jr, R.E.4
  • 12
    • 0022549920 scopus 로고
    • A receptor mediated pathway for cholesterol homeostasis
    • Brown MS, Goldstein JL (1986) A receptor mediated pathway for cholesterol homeostasis. Science 232:24-47
    • (1986) Science , vol.232 , pp. 24-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 13
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown MS, Goldstein JL (1997) The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89:331-340
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 14
    • 0033613147 scopus 로고    scopus 로고
    • A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
    • Brown MS, Goldstein JL (1999) A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc Natl Acad Sci USA 96:11041-11048
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11041-11048
    • Brown, M.S.1    Goldstein, J.L.2
  • 15
    • 0034681260 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
    • Brown MS, Ye J, Rawson RB, Goldstein JL (2000) Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 100:391-398
    • (2000) Cell , vol.100 , pp. 391-398
    • Brown, M.S.1    Ye, J.2    Rawson, R.B.3    Goldstein, J.L.4
  • 17
    • 0023598027 scopus 로고
    • Digestion, absorption and effects on cholesterol absorption of menhaden oil, fish oil concentrate and corn oil by rats
    • Chen IS, Hotta SS, Ikeda I, Cassidy MM, Sheppard AJ, Vahouny GV (1987) Digestion, absorption and effects on cholesterol absorption of menhaden oil, fish oil concentrate and corn oil by rats. J Nutr 117:1676-1680
    • (1987) J Nutr , vol.117 , pp. 1676-1680
    • Chen, I.S.1    Hotta, S.S.2    Ikeda, I.3    Cassidy, M.M.4    Sheppard, A.J.5    Vahouny, G.V.6
  • 18
    • 3042846012 scopus 로고    scopus 로고
    • In vivo regulation of SREBP-1c in skeletal muscle: Effects of nutritional status, glucose, insulin, and leptin
    • Commerford SR, Peng L, Dube JJ, O'Doherty RM (2004) In vivo regulation of SREBP-1c in skeletal muscle: effects of nutritional status, glucose, insulin, and leptin. Am J Physiol Regul Integr Comp Physiol 287:R218-R227
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.287
    • Commerford, S.R.1    Peng, L.2    Dube, J.J.3    O'Doherty, R.M.4
  • 19
    • 0027501003 scopus 로고
    • Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans
    • Dietschy JM, Turley SD, Spady DK (1993) Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J Lipid Res 34:1637-1659
    • (1993) J Lipid Res , vol.34 , pp. 1637-1659
    • Dietschy, J.M.1    Turley, S.D.2    Spady, D.K.3
  • 21
    • 0030911517 scopus 로고    scopus 로고
    • Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the luminal loop of sterol regulatory element-binding protein-2
    • Duncan EA, Brown MS, Goldstein JL, Sakai J (1997) Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the luminal loop of sterol regulatory element-binding protein-2. J Biol Chem 272:12778-12785
    • (1997) J Biol Chem , vol.272 , pp. 12778-12785
    • Duncan, E.A.1    Brown, M.S.2    Goldstein, J.L.3    Sakai, J.4
  • 22
    • 0032504202 scopus 로고    scopus 로고
    • Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning
    • Duncan EA, Dave UP, Sakai J, Goldstein JL, Brown MS (1998) Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning. J Biol Chem 273:17801-17809
    • (1998) J Biol Chem , vol.273 , pp. 17801-17809
    • Duncan, E.A.1    Dave, U.P.2    Sakai, J.3    Goldstein, J.L.4    Brown, M.S.5
  • 23
    • 0036202294 scopus 로고    scopus 로고
    • Dietary sphingomyelin suppresses intestinal cholesterol absorption by decreasing thermodynamic activity of cholesterol monomers
    • Eckhardt ER, Wang DQ, Donovan JM, Carey MC (2002) Dietary sphingomyelin suppresses intestinal cholesterol absorption by decreasing thermodynamic activity of cholesterol monomers. Gastroenterology 122:948-956
    • (2002) Gastroenterology , vol.122 , pp. 948-956
    • Eckhardt, E.R.1    Wang, D.Q.2    Donovan, J.M.3    Carey, M.C.4
  • 24
    • 0021811872 scopus 로고
    • Influence of age on secretion of cholesterol and synthesis of bile acids by the liver
    • Einarsson K, Nilsell K, Leijd B, Angelin B (1985) Influence of age on secretion of cholesterol and synthesis of bile acids by the liver. N Engl J Med 313:277-282
    • (1985) N Engl J Med , vol.313 , pp. 277-282
    • Einarsson, K.1    Nilsell, K.2    Leijd, B.3    Angelin, B.4
  • 25
    • 33744512299 scopus 로고    scopus 로고
    • Cholesterol and the interaction of proteins with membrane domains
    • Epand RM (2006) Cholesterol and the interaction of proteins with membrane domains. Prog Lipid Res 45:279-294
    • (2006) Prog Lipid Res , vol.45 , pp. 279-294
    • Epand, R.M.1
  • 26
    • 0033529560 scopus 로고    scopus 로고
    • Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins
    • Espenshade PJ, Cheng D, Goldstein JL, Brown MS (1999) Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins. J Biol Chem 274:22795-22804
    • (1999) J Biol Chem , vol.274 , pp. 22795-22804
    • Espenshade, P.J.1    Cheng, D.2    Goldstein, J.L.3    Brown, M.S.4
  • 27
    • 0037015073 scopus 로고    scopus 로고
    • Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER
    • Espenshade PJ, Li WP, Yabe D (2002) Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER. Proc Natl Acad Sci USA 99:11694-11699
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11694-11699
    • Espenshade, P.J.1    Li, W.P.2    Yabe, D.3
  • 28
    • 1542379024 scopus 로고    scopus 로고
    • Membrane topology of human insig-1, a protein regulator of lipid synthesis
    • Feramisco JD, Goldstein JL, Brown MS (2004) Membrane topology of human insig-1, a protein regulator of lipid synthesis. J Biol Chem 279:8487-8496
    • (2004) J Biol Chem , vol.279 , pp. 8487-8496
    • Feramisco, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 29
    • 0034235363 scopus 로고    scopus 로고
    • Regulation of sterol regulatory element binding protein 1 gene expression in liver: Role of insulin and protein kinase B/cAkt
    • Fleischmann M, Iynedjian PB (2000) Regulation of sterol regulatory element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt. Biochem J 349:13-17
    • (2000) Biochem J , vol.349 , pp. 13-17
    • Fleischmann, M.1    Iynedjian, P.B.2
  • 30
    • 0033607176 scopus 로고    scopus 로고
    • Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
    • Foretz M, Guichard C, Ferre P, Foufelle F (1999a) Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci USA 96:12737-12774
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12737-12774
    • Foretz, M.1    Guichard, C.2    Ferre, P.3    Foufelle, F.4
  • 33
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein JL, Brown MS (1990) Regulation of the mevalonate pathway. Nature 343:425-430
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 35
    • 30344452931 scopus 로고    scopus 로고
    • Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake
    • Gong Y, Lee JN, Lee PCW, Goldstein JL, Brown MS, Ye J (2006) Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake. Cell Metab 3:15-24
    • (2006) Cell Metab , vol.3 , pp. 15-24
    • Gong, Y.1    Lee, J.N.2    Lee, P.C.W.3    Goldstein, J.L.4    Brown, M.S.5    Ye, J.6
  • 36
    • 14144251157 scopus 로고    scopus 로고
    • Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c
    • Hegarty BD, Bobard A, Hainault I, Ferre P, Bossard P, Foufelle F (2005) Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c. Proc Natl Acad Sci USA 102:791-796
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 791-796
    • Hegarty, B.D.1    Bobard, A.2    Hainault, I.3    Ferre, P.4    Bossard, P.5    Foufelle, F.6
  • 37
    • 0021043541 scopus 로고
    • Role of acyl CoA:cholesterol acyltransferase in cholesterol absorption and its inhibition by 57-118 in the rabbit
    • Heider JG, Pickens CE, Kelly LA (1983) Role of acyl CoA:cholesterol acyltransferase in cholesterol absorption and its inhibition by 57-118 in the rabbit. J Lipid Res 24:1127-1134
    • (1983) J Lipid Res , vol.24 , pp. 1127-1134
    • Heider, J.G.1    Pickens, C.E.2    Kelly, L.A.3
  • 38
    • 0024450180 scopus 로고
    • Estrogen-induced gallstone formation in males. Relation to changes in serum and biliary lipids during hormonal treatment of prostatic carcinoma
    • Henriksson P, Einarsson K, Eriksson A, Kelter U, Angelin B (1989) Estrogen-induced gallstone formation in males. Relation to changes in serum and biliary lipids during hormonal treatment of prostatic carcinoma. J Clin Invest 84:811-816
    • (1989) J Clin Invest , vol.84 , pp. 811-816
    • Henriksson, P.1    Einarsson, K.2    Eriksson, A.3    Kelter, U.4    Angelin, B.5
  • 39
    • 0037930875 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway
    • Hirano Y, Murata S, Tanaka K, Shimizu M, Sato R (2003) Sterol regulatory element-binding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway. J Biol Chem 278:16809-16819
    • (2003) J Biol Chem , vol.278 , pp. 16809-16819
    • Hirano, Y.1    Murata, S.2    Tanaka, K.3    Shimizu, M.4    Sato, R.5
  • 40
    • 0035965231 scopus 로고    scopus 로고
    • Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway
    • Hirano Y, Yoshida M, Shimizu M, Sato R (2001) Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway. J Biol Chem 276:36431-36437
    • (2001) J Biol Chem , vol.276 , pp. 36431-36437
    • Hirano, Y.1    Yoshida, M.2    Shimizu, M.3    Sato, R.4
  • 41
    • 50549218397 scopus 로고
    • Hydrolysis of long-chain monoglycerides in micellar solution by pancreatic lipase
    • Hoffmann AF, Borgstrom B (1963) Hydrolysis of long-chain monoglycerides in micellar solution by pancreatic lipase. Biochim Biophys Acta 70:317-331
    • (1963) Biochim Biophys Acta , vol.70 , pp. 317-331
    • Hoffmann, A.F.1    Borgstrom, B.2
  • 42
    • 0032568557 scopus 로고    scopus 로고
    • Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice
    • Horton JD, Bashmakov Y, Shimomura I, Shimano H (1998) Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. Proc Natl Acad Sci USA 95:5987-5992
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5987-5992
    • Horton, J.D.1    Bashmakov, Y.2    Shimomura, I.3    Shimano, H.4
  • 43
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton JD, Goldstein JL, Brown MS (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109:1125-1131
    • (2002) J Clin Invest , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 45
    • 0141704191 scopus 로고    scopus 로고
    • Overexpression of SREBP-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver
    • Horton JD, Shimomura I, Ikemoto S, Bashmakov Y, Hammer RE (2003b) Overexpression of SREBP-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver. J Biol Chem 278:36652-36660
    • (2003) J Biol Chem , vol.278 , pp. 36652-36660
    • Horton, J.D.1    Shimomura, I.2    Ikemoto, S.3    Bashmakov, Y.4    Hammer, R.E.5
  • 46
    • 0030298339 scopus 로고    scopus 로고
    • Sterol resistance in CHO cells traced to point mutation in SREBP cleavage activating protein (SCAP)
    • Hua X, Nohturfft A, Goldstein JL, Brown MS (1996) Sterol resistance in CHO cells traced to point mutation in SREBP cleavage activating protein (SCAP). Cell 87:415-426
    • (1996) Cell , vol.87 , pp. 415-426
    • Hua, X.1    Nohturfft, A.2    Goldstein, J.L.3    Brown, M.S.4
  • 47
    • 0028820299 scopus 로고
    • Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection
    • Hua X, Sakai J, Ho YK, Goldstein JL, Brown MS (1995) Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection. J Biol Chem 270:29422-29427
    • (1995) J Biol Chem , vol.270 , pp. 29422-29427
    • Hua, X.1    Sakai, J.2    Ho, Y.K.3    Goldstein, J.L.4    Brown, M.S.5
  • 48
    • 0028960739 scopus 로고
    • Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13
    • Hua X, Wu J, Goldstein JL, Brown MS, Hobbs HH (1995) Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13. Genomics 25:667-673
    • (1995) Genomics , vol.25 , pp. 667-673
    • Hua, X.1    Wu, J.2    Goldstein, J.L.3    Brown, M.S.4    Hobbs, H.H.5
  • 49
    • 0033991176 scopus 로고    scopus 로고
    • A proposed model for the assembly of chylomicrons
    • Hussain MM (2000) A proposed model for the assembly of chylomicrons. Atherosclerosis 148:1-15
    • (2000) Atherosclerosis , vol.148 , pp. 1-15
    • Hussain, M.M.1
  • 51
    • 0034329593 scopus 로고    scopus 로고
    • Activation of protein kinase B/cAkt in hepatocytes is sufficient for the induction of expression of the gene encoding glucokinase
    • Iynedjian PB, Roth RA, Fleischmann M, Gjinovci A (2000) Activation of protein kinase B/cAkt in hepatocytes is sufficient for the induction of expression of the gene encoding glucokinase. Biochem J 351(Pt. 3):621-627
    • (2000) Biochem J , vol.351 , Issue.PART. 3 , pp. 621-627
    • Iynedjian, P.B.1    Roth, R.A.2    Fleischmann, M.3    Gjinovci, A.4
  • 52
    • 0036790994 scopus 로고    scopus 로고
    • The hypocholesterolemic agent LY295427 upregulates INSIG-1, identifying the INSIG-1 protein as a mediator of cholesterol homeostasis through SREBP
    • Janowski BA (2002) The hypocholesterolemic agent LY295427 upregulates INSIG-1, identifying the INSIG-1 protein as a mediator of cholesterol homeostasis through SREBP. Proc Natl Acad Sci USA 99:12675-12680
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12675-12680
    • Janowski, B.A.1
  • 54
    • 0025633321 scopus 로고
    • Effect of lovastatin on acyl-CoA: Cholesterol O-acyltransferase (ACAT) activity and the basolateral-membrane secretion of newly synthesized lipids by CaCo-2 cells
    • Kam NT, Albright E, Mathur S, Field FJ (1990) Effect of lovastatin on acyl-CoA: cholesterol O-acyltransferase (ACAT) activity and the basolateral-membrane secretion of newly synthesized lipids by CaCo-2 cells. Biochem J 272:427-433
    • (1990) Biochem J , vol.272 , pp. 427-433
    • Kam, N.T.1    Albright, E.2    Mathur, S.3    Field, F.J.4
  • 55
    • 0024514551 scopus 로고
    • Inhibition of acylcoenzyme A: Cholesterol acyltransferase activity in CaCo-2 cells results in intracellular triglyceride accumulation
    • Kam NT, Albright E, Mathur SN, Field FJ (1989) Inhibition of acylcoenzyme A: cholesterol acyltransferase activity in CaCo-2 cells results in intracellular triglyceride accumulation. J Lipid Res 30:371-377
    • (1989) J Lipid Res , vol.30 , pp. 371-377
    • Kam, N.T.1    Albright, E.2    Mathur, S.N.3    Field, F.J.4
  • 58
    • 2542418816 scopus 로고    scopus 로고
    • Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding protein-2 at serine residues 432 and 455 in vivo
    • Kotzka J, Lehr S, Roth G, Avci H, Knebel B, Muller-Wieland D (2004) Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding protein-2 at serine residues 432 and 455 in vivo. J Biol Chem 279:22404-22411
    • (2004) J Biol Chem , vol.279 , pp. 22404-22411
    • Kotzka, J.1    Lehr, S.2    Roth, G.3    Avci, H.4    Knebel, B.5    Muller-Wieland, D.6
  • 59
    • 23244465200 scopus 로고    scopus 로고
    • New insights into the genetic regulation of intestinal cholesterol absorption
    • Lammert F, Wang DQ (2005) New insights into the genetic regulation of intestinal cholesterol absorption. Gastroenterology 129:718-734
    • (2005) Gastroenterology , vol.129 , pp. 718-734
    • Lammert, F.1    Wang, D.Q.2
  • 61
    • 7244221504 scopus 로고    scopus 로고
    • Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1
    • Lee JN, Ye J (2004) Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1. J Biol Chem 279:45257-45265
    • (2004) J Biol Chem , vol.279 , pp. 45257-45265
    • Lee, J.N.1    Ye, J.2
  • 63
    • 0015307131 scopus 로고
    • Subfractionation of S f 4-10 5, S f 4-20 and high density lipoproteins
    • Lindgren FT, Jensen LC, Wills RD, Stevens GR (1972) Subfractionation of S f 4-10 5, S f 4-20 and high density lipoproteins. Lipids 7:194-201
    • (1972) Lipids , vol.7 , pp. 194-201
    • Lindgren, F.T.1    Jensen, L.C.2    Wills, R.D.3    Stevens, G.R.4
  • 65
    • 0039842456 scopus 로고    scopus 로고
    • Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase
    • Magana MM, Koo SH, Towle HC, Osborne TF (2000) Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase. J Biol Chem 275:4726-4733
    • (2000) J Biol Chem , vol.275 , pp. 4726-4733
    • Magana, M.M.1    Koo, S.H.2    Towle, H.C.3    Osborne, T.F.4
  • 66
    • 22744445281 scopus 로고    scopus 로고
    • Overview of caloric restriction and ageing
    • Masoro EJ (2005) Overview of caloric restriction and ageing. Mech Ageing Dev 126:913-22
    • (2005) Mech Ageing Dev , vol.126 , pp. 913-922
    • Masoro, E.J.1
  • 69
    • 0031568872 scopus 로고    scopus 로고
    • Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF2)
    • Miserez AR, Cao G, Probst LC, Hobbs HH (1997) Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF2). Genomics 40:31-40
    • (1997) Genomics , vol.40 , pp. 31-40
    • Miserez, A.R.1    Cao, G.2    Probst, L.C.3    Hobbs, H.H.4
  • 70
    • 0026068697 scopus 로고
    • The immediate-early growth response in regenerating liver and insulin-stimulated H-35 cells: Comparison with serum-stimulated 3T3 cells and identification of 41 novel immediate-early genes
    • Mohn KL, Laz TM, Hsu J-C, Melby AE, Bravo R, Taub R (1991) The immediate-early growth response in regenerating liver and insulin-stimulated H-35 cells: comparison with serum-stimulated 3T3 cells and identification of 41 novel immediate-early genes. Mol Cell Biol 11:381-390
    • (1991) Mol Cell Biol , vol.11 , pp. 381-390
    • Mohn, K.L.1    Laz, T.M.2    Hsu, J.-C.3    Melby, A.E.4    Bravo, R.5    Taub, R.6
  • 71
    • 0042413939 scopus 로고    scopus 로고
    • Effects of ageing on insulin secretion and action
    • Moller N, Gormsen L, Fuglsang J, Gjedsted J (2003) Effects of ageing on insulin secretion and action. Horm Res 60:102-104
    • (2003) Horm Res , vol.60 , pp. 102-104
    • Moller, N.1    Gormsen, L.2    Fuglsang, J.3    Gjedsted, J.4
  • 72
    • 0034730504 scopus 로고    scopus 로고
    • The roles of sterol regulatory element-binding proteins in the transactivation of the rat ATP citrate-lyase promoter
    • Moon YA, Lee JJ, Park SW, Ahn YH, Kim KS (2000) The roles of sterol regulatory element-binding proteins in the transactivation of the rat ATP citrate-lyase promoter. J Biol Chem 275:30280-30286
    • (2000) J Biol Chem , vol.275 , pp. 30280-30286
    • Moon, Y.A.1    Lee, J.J.2    Park, S.W.3    Ahn, Y.H.4    Kim, K.S.5
  • 73
    • 0035977004 scopus 로고    scopus 로고
    • Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins
    • Moon YA, Shah NA, Mohapatra S, Warrington JA, Horton JD (2001) Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins. J Biol Chem 276:45358-45366
    • (2001) J Biol Chem , vol.276 , pp. 45358-45366
    • Moon, Y.A.1    Shah, N.A.2    Mohapatra, S.3    Warrington, J.A.4    Horton, J.D.5
  • 74
    • 0025352716 scopus 로고
    • Effect of eicosapentaenoic acid on triacylglycerol transport in CaCo-2 cells
    • Murthy S, Albright E, Mathur SN, Field FJ (1990) Effect of eicosapentaenoic acid on triacylglycerol transport in CaCo-2 cells. Biochim Biophys Acta 1045:147-155
    • (1990) Biochim Biophys Acta , vol.1045 , pp. 147-155
    • Murthy, S.1    Albright, E.2    Mathur, S.N.3    Field, F.J.4
  • 75
    • 0026655389 scopus 로고
    • Apolipoprotein B mRNA abundance is decreased by eicosapentaenoic acid in CaCo-2 cells. Effect on the synthesis and secretion of apolipoprotein B
    • Murthy S, Albright E, Mathur SN, Davidson NO, Field FJ (1992) Apolipoprotein B mRNA abundance is decreased by eicosapentaenoic acid in CaCo-2 cells. Effect on the synthesis and secretion of apolipoprotein B. Arterioscler Thromb 12:691-700
    • (1992) Arterioscler Thromb , vol.12 , pp. 691-700
    • Murthy, S.1    Albright, E.2    Mathur, S.N.3    Davidson, N.O.4    Field, F.J.5
  • 77
    • 0040368298 scopus 로고    scopus 로고
    • Composite co-activator ARC mediates chromatin-directed transcriptional activation
    • Naar AM, Beaurang PA, Zhou S, Abraham S, Solomon W, Tjian R (1999) Composite co-activator ARC mediates chromatin-directed transcriptional activation. Nature 398:828-832
    • (1999) Nature , vol.398 , pp. 828-832
    • Naar, A.M.1    Beaurang, P.A.2    Zhou, S.3    Abraham, S.4    Solomon, W.5    Tjian, R.6
  • 78
    • 0035080226 scopus 로고    scopus 로고
    • Dimerization of sterol regulatory element-binding protein 2 via the helix-loop-helix-leucine zipper domain is a prerequisite for its nuclear localization mediated by importin beta
    • Nagoshi E, Yoneda Y (2001) Dimerization of sterol regulatory element-binding protein 2 via the helix-loop-helix-leucine zipper domain is a prerequisite for its nuclear localization mediated by importin beta. Mol Cell Biol 21:2779-2789
    • (2001) Mol Cell Biol , vol.21 , pp. 2779-2789
    • Nagoshi, E.1    Yoneda, Y.2
  • 79
    • 0032815863 scopus 로고    scopus 로고
    • Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin beta with HLH-Zip
    • Nagoshi E, Immoto N, Sato R, Yoneda Y (1999) Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin beta with HLH-Zip. Mol Biol Cell 10:2221-2233
    • (1999) Mol Biol Cell , vol.10 , pp. 2221-2233
    • Nagoshi, E.1    Immoto, N.2    Sato, R.3    Yoneda, Y.4
  • 80
    • 0028865447 scopus 로고
    • Transcriptional regulation of rat hepatic low-density lipoprotein receptor and cholesterol 7 alpha hydroxylase by thyroid hormone
    • Ness GC, Lopez D (1995) Transcriptional regulation of rat hepatic low-density lipoprotein receptor and cholesterol 7 alpha hydroxylase by thyroid hormone. Arch Biochem Biophys 323:404-408
    • (1995) Arch Biochem Biophys , vol.323 , pp. 404-408
    • Ness, G.C.1    Lopez, D.2
  • 82
    • 0032720785 scopus 로고    scopus 로고
    • The cholesterol-lowering action of plant stanol esters
    • Nguyen TT (1999) The cholesterol-lowering action of plant stanol esters. J Nutr 129:2109-2112
    • (1999) J Nutr , vol.129 , pp. 2109-2112
    • Nguyen, T.T.1
  • 83
    • 0027536829 scopus 로고
    • Effect of lovastatin on cholesterol absorption in cholesterol-fed rabbits
    • Nielsen LB, Stender S, Kjeldsen K (1993) Effect of lovastatin on cholesterol absorption in cholesterol-fed rabbits. Pharmacol Toxicol 72:148-151
    • (1993) Pharmacol Toxicol , vol.72 , pp. 148-151
    • Nielsen, L.B.1    Stender, S.2    Kjeldsen, K.3
  • 84
    • 0032573056 scopus 로고    scopus 로고
    • Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavageactivating protein (SCAP), but not sterol-resistant mutants Y298C or D443N
    • Nohturfft A, Brown MS, Goldstein JL (1998a) Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavageactivating protein (SCAP), but not sterol-resistant mutants Y298C or D443N. Proc Natl Acad Sci USA 95:12848-12853
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12848-12853
    • Nohturfft, A.1    Brown, M.S.2    Goldstein, J.L.3
  • 85
    • 0032479439 scopus 로고    scopus 로고
    • Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain
    • Nohturfft A, Brown MS, Goldstein JL (1998b) Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain. J Biol Chem 273:17243-17250
    • (1998) J Biol Chem , vol.273 , pp. 17243-17250
    • Nohturfft, A.1    Brown, M.S.2    Goldstein, J.L.3
  • 86
    • 0034604350 scopus 로고    scopus 로고
    • Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes
    • Nohturfft A, Yabe D, Goldstein JL, Brown MS, Espenshade PJ (2000) Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes. Cell 102:315-323
    • (2000) Cell , vol.102 , pp. 315-323
    • Nohturfft, A.1    Yabe, D.2    Goldstein, J.L.3    Brown, M.S.4    Espenshade, P.J.5
  • 87
    • 0016255066 scopus 로고
    • Fatty acid-binding protein in small intestine. Identification, isolation, and evidence for its role in cellular fatty acid transport
    • Ockner RK, Manning JA (1974) Fatty acid-binding protein in small intestine. Identification, isolation, and evidence for its role in cellular fatty acid transport. J Clin Invest 54:326-338
    • (1974) J Clin Invest , vol.54 , pp. 326-338
    • Ockner, R.K.1    Manning, J.A.2
  • 88
    • 0014630115 scopus 로고
    • Very low density lipoproteins in intestinal lymph: Role in triglyceride and cholesterol transport during fat absorption
    • Ockner RK, Hughes FB, Isselbacher KJ (1969) Very low density lipoproteins in intestinal lymph: role in triglyceride and cholesterol transport during fat absorption. J Clin Invest 48:2367-2373
    • (1969) J Clin Invest , vol.48 , pp. 2367-2373
    • Ockner, R.K.1    Hughes, F.B.2    Isselbacher, K.J.3
  • 89
    • 25444463073 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A1: A cell cholesterol exporter that protects against cardiovascular disease
    • Oram JF, Heinecke JW (2005) ATP-binding cassette transporter A1: a cell cholesterol exporter that protects against cardiovascular disease. Physiol Rev 85:1343-1372
    • (2005) Physiol Rev , vol.85 , pp. 1343-1372
    • Oram, J.F.1    Heinecke, J.W.2
  • 90
    • 0034693259 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): Key regulators of nutritional homeostasis and insulin action
    • Osborne TF (2000) Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action. J Biol Chem 275:32379-32382
    • (2000) J Biol Chem , vol.275 , pp. 32379-32382
    • Osborne, T.F.1
  • 91
    • 0036099122 scopus 로고    scopus 로고
    • Phytosterols that are naturally present in commercial corn oil significantly reduce cholesterol absorption in humans
    • Ostlund RE Jr, Racette SB, Okeke A, Stenson WF (2002) Phytosterols that are naturally present in commercial corn oil significantly reduce cholesterol absorption in humans. Am J Clin Nutr 75:1000-1004
    • (2002) Am J Clin Nutr , vol.75 , pp. 1000-1004
    • Ostlund Jr, R.E.1    Racette, S.B.2    Okeke, A.3    Stenson, W.F.4
  • 93
    • 28044438219 scopus 로고    scopus 로고
    • Enzymes involved in the formation and transformation of steroid hormones in the fetal and placental compartments
    • Pasqualini JR (2005) Enzymes involved in the formation and transformation of steroid hormones in the fetal and placental compartments. J Steroid Biochem Mol Biol 97:401-415
    • (2005) J Steroid Biochem Mol Biol , vol.97 , pp. 401-415
    • Pasqualini, J.R.1
  • 94
    • 0031213639 scopus 로고    scopus 로고
    • Cloning, human chromosomal assignment, and adipose and hepatic expression of the CL-6/INSIG1 gene
    • Peng Y, Schwarz EJ, Lazar MA, Genin A, Spinner NB, Taub R (1997) Cloning, human chromosomal assignment, and adipose and hepatic expression of the CL-6/INSIG1 gene. Genomics 43:278-284
    • (1997) Genomics , vol.43 , pp. 278-284
    • Peng, Y.1    Schwarz, E.J.2    Lazar, M.A.3    Genin, A.4    Spinner, N.B.5    Taub, R.6
  • 95
    • 32244434747 scopus 로고    scopus 로고
    • Caveolin-1 as a potential new therapeutic target in multiple myeloma
    • Podar K, Anderson KC (2006) Caveolin-1 as a potential new therapeutic target in multiple myeloma. Cancer Lett 233:10-15
    • (2006) Cancer Lett , vol.233 , pp. 10-15
    • Podar, K.1    Anderson, K.C.2
  • 96
    • 0347356334 scopus 로고    scopus 로고
    • Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1 (SREBP1) mRNAs in hepatocytes
    • Ribaux PG, Iynedjian PB (2003) Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1 (SREBP1) mRNAs in hepatocytes. Biochem J 376:697-705
    • (2003) Biochem J , vol.376 , pp. 697-705
    • Ribaux, P.G.1    Iynedjian, P.B.2
  • 97
    • 0032510318 scopus 로고    scopus 로고
    • Rosenblum SB, Huynh T, Afonso A, Davis HR Jr, Yumibe N, Clader JW, Burnett DA (1998) Discovery of 1-(4-fluorophenyl)-(3R)-[3- (4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4-hydroxyphenyl)- 2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption. J Med Chem 41: 973-980
    • Rosenblum SB, Huynh T, Afonso A, Davis HR Jr, Yumibe N, Clader JW, Burnett DA (1998) Discovery of 1-(4-fluorophenyl)-(3R)-[3- (4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4-hydroxyphenyl)- 2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption. J Med Chem 41: 973-980
  • 99
    • 0034721772 scopus 로고    scopus 로고
    • MAP kinases Erk1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro
    • Roth G, Kotzka J, Kremer L, Lehr S, Lohaus C, Meyer HE, Krone W, Muller-Wieland D (2000) MAP kinases Erk1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro. J Biol Chem 275:33302-33307
    • (2000) J Biol Chem , vol.275 , pp. 33302-33307
    • Roth, G.1    Kotzka, J.2    Kremer, L.3    Lehr, S.4    Lohaus, C.5    Meyer, H.E.6    Krone, W.7    Muller-Wieland, D.8
  • 100
    • 0032185770 scopus 로고    scopus 로고
    • Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells
    • Sakai J, Rawson RB, Espenshade PJ, Cheng D, Seegmiller AC, Goldstein JL, Brown MS (1998) Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells. Mol Cell 2:505-514
    • (1998) Mol Cell , vol.2 , pp. 505-514
    • Sakai, J.1    Rawson, R.B.2    Espenshade, P.J.3    Cheng, D.4    Seegmiller, A.C.5    Goldstein, J.L.6    Brown, M.S.7
  • 101
    • 0029958652 scopus 로고    scopus 로고
    • Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2
    • Sato R, Inoue J, Kawabe Y, Kodama T, Takano T, Maeda M (1996) Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2. J Biol Chem 271:26461-26464
    • (1996) J Biol Chem , vol.271 , pp. 26461-26464
    • Sato, R.1    Inoue, J.2    Kawabe, Y.3    Kodama, T.4    Takano, T.5    Maeda, M.6
  • 102
    • 0028839010 scopus 로고
    • Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver
    • Sheng Z, Otani H, Brown MS, Goldstein JL (1995) Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver. Proc Natl Acad Sci USA 92:935-938
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 935-938
    • Sheng, Z.1    Otani, H.2    Brown, M.S.3    Goldstein, J.L.4
  • 103
    • 0029797604 scopus 로고    scopus 로고
    • Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
    • Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL (1996) Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J Biol Chem 98:1575-1584
    • (1996) J Biol Chem , vol.98 , pp. 1575-1584
    • Shimano, H.1    Horton, J.D.2    Hammer, R.E.3    Shimomura, I.4    Brown, M.S.5    Goldstein, J.L.6
  • 104
    • 0030907175 scopus 로고    scopus 로고
    • Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
    • Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL (1997) Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest 99:846-854
    • (1997) J Clin Invest , vol.99 , pp. 846-854
    • Shimano, H.1    Horton, J.D.2    Shimomura, I.3    Hammer, R.E.4    Brown, M.S.5    Goldstein, J.L.6
  • 105
    • 0030961960 scopus 로고    scopus 로고
    • Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
    • Shimomura I, Shimano H, Horton JD, Goldstein JL, Brown MS (1997) Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. J Clin Invest 99:838-845
    • (1997) J Clin Invest , vol.99 , pp. 838-845
    • Shimomura, I.1    Shimano, H.2    Horton, J.D.3    Goldstein, J.L.4    Brown, M.S.5
  • 106
    • 0000905362 scopus 로고
    • C14-Cholesterol. V. obligatory function of bile in intestinal absorption of cholesterol
    • Siperstein MD, Chaikoff IL, Reinhardt WO (1952) C14-Cholesterol. V. obligatory function of bile in intestinal absorption of cholesterol. J Biol Chem 198:111-114
    • (1952) J Biol Chem , vol.198 , pp. 111-114
    • Siperstein, M.D.1    Chaikoff, I.L.2    Reinhardt, W.O.3
  • 107
    • 0345461478 scopus 로고    scopus 로고
    • Putative metabolic effects of the liver X receptor (LXR)
    • Steffensen KR, Gustafsson JA (2004) Putative metabolic effects of the liver X receptor (LXR). Diabetes 53(Suppl. 1):S36-S42
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Steffensen, K.R.1    Gustafsson, J.A.2
  • 109
    • 0037697148 scopus 로고    scopus 로고
    • Distinct endosomal compartments in early trafficking of low density lipoprotein-derived cholesterol
    • Sugii S, Reid PC, Ohgami N, Du H, Chang TY (2003) Distinct endosomal compartments in early trafficking of low density lipoprotein-derived cholesterol. J Biol Chem 278:27180-27189
    • (2003) J Biol Chem , vol.278 , pp. 27180-27189
    • Sugii, S.1    Reid, P.C.2    Ohgami, N.3    Du, H.4    Chang, T.Y.5
  • 110
    • 22544466429 scopus 로고    scopus 로고
    • Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro
    • Sun LP, Li L, Goldstein JL, Brown MS (2005) Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro. J Biol Chem 280:26483-26490
    • (2005) J Biol Chem , vol.280 , pp. 26483-26490
    • Sun, L.P.1    Li, L.2    Goldstein, J.L.3    Brown, M.S.4
  • 111
    • 0344270908 scopus 로고    scopus 로고
    • Transcription-dependent degradation controls the stability of the SREBP family of transcription factors
    • Sundqvist A, Ericsson J (2003) Transcription-dependent degradation controls the stability of the SREBP family of transcription factors. Proc Natl Acad Sci USA 100:13833-13838
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 13833-13838
    • Sundqvist, A.1    Ericsson, J.2
  • 112
    • 0037503924 scopus 로고    scopus 로고
    • Liver X receptor signaling pathways in cardiovascular disease
    • Tontonoz P, Mangelsdorf DJ (2003) Liver X receptor signaling pathways in cardiovascular disease. Mol Endocrinol 17:985-993
    • (2003) Mol Endocrinol , vol.17 , pp. 985-993
    • Tontonoz, P.1    Mangelsdorf, D.J.2
  • 113
    • 0023490564 scopus 로고
    • Polarized secretion of newly synthesized lipoproteins by the Caco-2 human intestinal cell line
    • Traber MG, Kayden HJ, Rindler MJ (1987) Polarized secretion of newly synthesized lipoproteins by the Caco-2 human intestinal cell line. J Lipid Res 28:1350-1363
    • (1987) J Lipid Res , vol.28 , pp. 1350-1363
    • Traber, M.G.1    Kayden, H.J.2    Rindler, M.J.3
  • 114
    • 0021731040 scopus 로고
    • Evidence for separate pathways of chylomicron and very low-density lipoprotein assembly and transport by rat small intestine
    • Tso P, Drake DS, Black DD, Sabesin SM (1984) Evidence for separate pathways of chylomicron and very low-density lipoprotein assembly and transport by rat small intestine. Am J Physiol 247:G599-G610
    • (1984) Am J Physiol , vol.247
    • Tso, P.1    Drake, D.S.2    Black, D.D.3    Sabesin, S.M.4
  • 115
    • 0038509061 scopus 로고    scopus 로고
    • Sterol absorption by the small intestine
    • Turley SD, Dietschy JM (2003) Sterol absorption by the small intestine. Curr Opin Lipidol 14:233-240
    • (2003) Curr Opin Lipidol , vol.14 , pp. 233-240
    • Turley, S.D.1    Dietschy, J.M.2
  • 116
    • 0031705365 scopus 로고    scopus 로고
    • Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol diets
    • Turley SD, Schwarz M, Spady DK, Dietschy JM (1998) Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol diets. Hepatology 28:1088-1094
    • (1998) Hepatology , vol.28 , pp. 1088-1094
    • Turley, S.D.1    Schwarz, M.2    Spady, D.K.3    Dietschy, J.M.4
  • 118
    • 0019408534 scopus 로고
    • Lymphatic absorption of shellfish sterols and their effects on cholesterol absorption
    • Vahouny GV, Connor WE, Roy T, Lin DS, Gallo LL (1981) Lymphatic absorption of shellfish sterols and their effects on cholesterol absorption. Am J Clin Nutr 34:507-513
    • (1981) Am J Clin Nutr , vol.34 , pp. 507-513
    • Vahouny, G.V.1    Connor, W.E.2    Roy, T.3    Lin, D.S.4    Gallo, L.L.5
  • 120
    • 0017842336 scopus 로고
    • Effect of aging on biliary lipid composition and bile acid metabolism in normal Chilean women
    • Valdivieso V, Palma R, Wunkhaus R, Antezana C, Severin C, Contreras A (1978) Effect of aging on biliary lipid composition and bile acid metabolism in normal Chilean women. Gastroenterology 74(5 Pt 1):871-874
    • (1978) Gastroenterology , vol.74 , Issue.5 PART 1 , pp. 871-874
    • Valdivieso, V.1    Palma, R.2    Wunkhaus, R.3    Antezana, C.4    Severin, C.5    Contreras, A.6
  • 121
    • 0026623506 scopus 로고
    • Pravastatin lowers serum cholesterol, cholesterol-precursor sterols, fecal steroids, and cholesterol absorption in man
    • Vanhanen H, Kesaniemi YA, Miettinen TA (1992) Pravastatin lowers serum cholesterol, cholesterol-precursor sterols, fecal steroids, and cholesterol absorption in man. Metabolism 41:588-595
    • (1992) Metabolism , vol.41 , pp. 588-595
    • Vanhanen, H.1    Kesaniemi, Y.A.2    Miettinen, T.A.3
  • 122
    • 0029958885 scopus 로고    scopus 로고
    • Complete mapping of crystallization pathways during cholesterol precipitation from model bile: Influence of physical-chemical variables of pathophysiologic relevance and identification of a stable liquid crystalline state in cold, dilute and hydrophilic bile salt-containing systems
    • Wang DQ, Carey MC (1996) Complete mapping of crystallization pathways during cholesterol precipitation from model bile: influence of physical-chemical variables of pathophysiologic relevance and identification of a stable liquid crystalline state in cold, dilute and hydrophilic bile salt-containing systems. J Lipid Res 37:606-630
    • (1996) J Lipid Res , vol.37 , pp. 606-630
    • Wang, D.Q.1    Carey, M.C.2
  • 123
    • 14444286453 scopus 로고    scopus 로고
    • Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt
    • Wang D, Sul HS (1998) Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt. J Biol Chem 273:25420-25426
    • (1998) J Biol Chem , vol.273 , pp. 25420-25426
    • Wang, D.1    Sul, H.S.2
  • 124
    • 0036846873 scopus 로고    scopus 로고
    • Aging per se is an independent risk factor for cholesterol gallstone formation in gallstone susceptible mice
    • Wang DQ (2002) Aging per se is an independent risk factor for cholesterol gallstone formation in gallstone susceptible mice. J Lipid Res 43:1950-1959
    • (2002) J Lipid Res , vol.43 , pp. 1950-1959
    • Wang, D.Q.1
  • 125
    • 2542566516 scopus 로고    scopus 로고
    • New concepts of mechanisms of intestinal cholesterol absorption
    • Wang DQ (2003) New concepts of mechanisms of intestinal cholesterol absorption. Ann Hepatol 2:113-121
    • (2003) Ann Hepatol , vol.2 , pp. 113-121
    • Wang, D.Q.1
  • 126
    • 0032953973 scopus 로고    scopus 로고
    • Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis
    • Wang DQ, Lammert F, Cohen DE, Paigen B, Carey MC (1999) Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis. Am J Physiol 276(3 Pt 1):G751-G760
    • (1999) Am J Physiol , vol.276 , Issue.3 PART 1
    • Wang, D.Q.1    Lammert, F.2    Cohen, D.E.3    Paigen, B.4    Carey, M.C.5
  • 127
    • 0041965752 scopus 로고    scopus 로고
    • Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: Studies in the gallstone-susceptible mouse
    • Wang DQ, Tazuma S, Cohen DE, Carey MC (2003) Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstone-susceptible mouse. Am J Physiol Gastrointest Liver Physiol 285:G494-G502
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285
    • Wang, D.Q.1    Tazuma, S.2    Cohen, D.E.3    Carey, M.C.4
  • 128
    • 3242694494 scopus 로고    scopus 로고
    • Estrogen receptor alpha, but not beta, plays a major role in 17-beta-estradiol-induced murine cholesterol gallstones
    • Wang HH, Afdhal NH, Wang DQ (2004) Estrogen receptor alpha, but not beta, plays a major role in 17-beta-estradiol-induced murine cholesterol gallstones. Gastroenterology 127:239-249
    • (2004) Gastroenterology , vol.127 , pp. 239-249
    • Wang, H.H.1    Afdhal, N.H.2    Wang, D.Q.3
  • 129
    • 0028225462 scopus 로고
    • SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
    • Wang X, Sato R, Brown MS, Hua X, Goldstein JL (1994) SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell 77:53-62
    • (1994) Cell , vol.77 , pp. 53-62
    • Wang, X.1    Sato, R.2    Brown, M.S.3    Hua, X.4    Goldstein, J.L.5
  • 130
    • 7044223211 scopus 로고    scopus 로고
    • Maintaining cholesterol homeostasis: Sterol regulatory element-binding proteins
    • Weber LW, Boll M, Stampfl A (2004) Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins. World J Gastroenterol 10:3081-3087
    • (2004) World J Gastroenterol , vol.10 , pp. 3081-3087
    • Weber, L.W.1    Boll, M.2    Stampfl, A.3
  • 131
    • 0036792050 scopus 로고    scopus 로고
    • Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins
    • Yabe D, Brown MS, Goldstein JL (2002) Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins. Proc Natl Acad Sci USA 99:12753-12758
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12753-12758
    • Yabe, D.1    Brown, M.S.2    Goldstein, J.L.3
  • 132
    • 33645928247 scopus 로고    scopus 로고
    • Heterozygous familial hypercholesterolemia: An underrecognized cause of early cardiovascular disease
    • Yuan G, Wang J Hegele RA (2006) Heterozygous familial hypercholesterolemia: an underrecognized cause of early cardiovascular disease. Can Med Assoc J 174:1124-1129
    • (2006) Can Med Assoc J , vol.174 , pp. 1124-1129
    • Yuan, G.1    Wang, J.2    Hegele, R.A.3
  • 134
    • 33644651160 scopus 로고    scopus 로고
    • Liver X receptors as integrators of metabolic and inflammatory signaling
    • Zelcer N, Tontonoz P (2006) Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest 116:607-614
    • (2006) J Clin Invest , vol.116 , pp. 607-614
    • Zelcer, N.1    Tontonoz, P.2
  • 135
    • 0013809384 scopus 로고
    • The composition and structure of lymph chylomicrons in dog, rat, and man
    • Zilversmit DB (1965) The composition and structure of lymph chylomicrons in dog, rat, and man. J Clin Invest 44:1610-1622
    • (1965) J Clin Invest , vol.44 , pp. 1610-1622
    • Zilversmit, D.B.1


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