-
1
-
-
0035101931
-
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice
-
Alberti S, Schuster G, Parini P, Feltkamp D, Diczfalusy U, Rudling M, Angelin B, Bjorkhem I, Pettersson S, Gustafsson JA: Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice. J Clin Invest 107:565-573, 2001
-
(2001)
J Clin Invest
, vol.107
, pp. 565-573
-
-
Alberti, S.1
Schuster, G.2
Parini, P.3
Feltkamp, D.4
Diczfalusy, U.5
Rudling, M.6
Angelin, B.7
Bjorkhem, I.8
Pettersson, S.9
Gustafsson, J.A.10
-
2
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
-
Peet DJ, Turley SD, Ma W, Janowski BA, Lobaccaro JM, Hammer RE, Mangelsdorf DJ: Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell 93:693-704, 1998
-
(1998)
Cell
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.M.5
Hammer, R.E.6
Mangelsdorf, D.J.7
-
3
-
-
0032871502
-
Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol
-
Ntambi JM: Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J Lipid Res 40:1549-1558, 1999
-
(1999)
J Lipid Res
, vol.40
, pp. 1549-1558
-
-
Ntambi, J.M.1
-
4
-
-
0034453225
-
Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha
-
Tobin KA, Steineger HH, Alberti S, Spydevold O, Auwerx J, Gustafsson JÅ, Nebb HI: Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha. Mol Endocrinol 14:741-752, 2000
-
(2000)
Mol Endocrinol
, vol.14
, pp. 741-752
-
-
Tobin, K.A.1
Steineger, H.H.2
Alberti, S.3
Spydevold, O.4
Auwerx, J.5
Gustafsson, J.Å.6
Nebb, H.I.7
-
5
-
-
17744376173
-
A PPAR gamma-LXR-ABCA 1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
-
Chawla A, Boisvert WA, Lee CH, Laffitte BA, Barak Y, Joseph SB, Liao D, Nagy L, Edwards PA, Curtiss LK, Evans RM, Tontonoz P: A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol Cell 7:161-171, 2001
-
(2001)
Mol Cell
, vol.7
, pp. 161-171
-
-
Chawla, A.1
Boisvert, W.A.2
Lee, C.H.3
Laffitte, B.A.4
Barak, Y.5
Joseph, S.B.6
Liao, D.7
Nagy, L.8
Edwards, P.A.9
Curtiss, L.K.10
Evans, R.M.11
Tontonoz, P.12
-
6
-
-
0034637128
-
ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR
-
Schwartz K, Lawn RM, Wade DP: ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR. Biochem Biophys Res Commun 274:794-802, 2000
-
(2000)
Biochem Biophys Res Commun
, vol.274
, pp. 794-802
-
-
Schwartz, K.1
Lawn, R.M.2
Wade, D.P.3
-
7
-
-
0034623288
-
Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor
-
Costet P, Luo Y, Wang N, Tall AR: Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J Biol Chem 275:28240-28245, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 28240-28245
-
-
Costet, P.1
Luo, Y.2
Wang, N.3
Tall, A.R.4
-
8
-
-
0347034082
-
Characterization of the human ABCG1 gene: Liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein
-
Kennedy MA, Venkateswaran A, Tarr PT, Xenarios I, Kudoh J, Shimizu N, Edwards PA: Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein. J Biol Chem 276:39438-39447, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 39438-39447
-
-
Kennedy, M.A.1
Venkateswaran, A.2
Tarr, P.T.3
Xenarios, I.4
Kudoh, J.5
Shimizu, N.6
Edwards, P.A.7
-
9
-
-
0035955326
-
The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages
-
Engel T, Lorkowski S, Lueken A, Rust S, Schluter B, Berger G, Cullen P, Assmann G: The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages. Biochem Biophys Res Commun 288:483-488, 2001
-
(2001)
Biochem Biophys Res Commun
, vol.288
, pp. 483-488
-
-
Engel, T.1
Lorkowski, S.2
Lueken, A.3
Rust, S.4
Schluter, B.5
Berger, G.6
Cullen, P.7
Assmann, G.8
-
10
-
-
0037166261
-
Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta
-
Repa JJ, Berge KE, Pomajzl C, Richardson JA, Hobbs H, Mangelsdorf DJ: Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta. J Biol Chem 277:18793-18800, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 18793-18800
-
-
Repa, J.J.1
Berge, K.E.2
Pomajzl, C.3
Richardson, J.A.4
Hobbs, H.5
Mangelsdorf, D.J.6
-
11
-
-
0035895202
-
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes
-
Laffitte BA, Repa JJ, Joseph SB, Wilpitz DC, Kast HR, Mangelsdorf DJ, Tontonoz P: LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. Proc Natl Acad Sci U S A 98:507-512, 2001
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 507-512
-
-
Laffitte, B.A.1
Repa, J.J.2
Joseph, S.B.3
Wilpitz, D.C.4
Kast, H.R.5
Mangelsdorf, D.J.6
Tontonoz, P.7
-
12
-
-
0037199994
-
Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages: A critical role for nuclear liver X receptors alpha and beta
-
Mak PA, Laffitte BA, Desrumaux C, Joseph SB, Curtiss LK, Mangelsdorf DJ, Tontonoz P, Edwards PA: Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages: a critical role for nuclear liver X receptors alpha and beta. J Biol Chem 277:31900-31908, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 31900-31908
-
-
Mak, P.A.1
Laffitte, B.A.2
Desrumaux, C.3
Joseph, S.B.4
Curtiss, L.K.5
Mangelsdorf, D.J.6
Tontonoz, P.7
Edwards, P.A.8
-
13
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
-
Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro JM, Shimomura I, Shan B, Brown MS, Goldstein JL, Mangelsdorf DJ: Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev 14:2819-2830, 2000
-
(2000)
Genes Dev
, vol.14
, pp. 2819-2830
-
-
Repa, J.J.1
Liang, G.2
Ou, J.3
Bashmakov, Y.4
Lobaccaro, J.M.5
Shimomura, I.6
Shan, B.7
Brown, M.S.8
Goldstein, J.L.9
Mangelsdorf, D.J.10
-
14
-
-
0035047709
-
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter
-
Yoshikawa T, Shimano H, Amemiya-Kudo M, Yahagi N, Hasty AH, Matsuzaka T, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Kimura S, Ishibashi S, Yamada N: Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter. Mol Cell Biol 21:2991-3000, 2001
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2991-3000
-
-
Yoshikawa, T.1
Shimano, H.2
Amemiya-Kudo, M.3
Yahagi, N.4
Hasty, A.H.5
Matsuzaka, T.6
Okazaki, H.7
Tamura, Y.8
Iizuka, Y.9
Ohashi, K.10
Osuga, J.11
Harada, K.12
Gotoda, T.13
Kimura, S.14
Ishibashi, S.15
Yamada, N.16
-
15
-
-
0037155935
-
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
-
Tobin KA, Ulven SM, Schuster GU, Steineger HH, Andresen SM, Gustafsson JÅ, Nebb HI: Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis. J Biol Chem 277:10691-10697, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 10691-10697
-
-
Tobin, K.A.1
Ulven, S.M.2
Schuster, G.U.3
Steineger, H.H.4
Andresen, S.M.5
Gustafsson, J.Å.6
Nebb, H.I.7
-
16
-
-
0037192797
-
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors
-
Joseph SB, Laffitte BA, Patel PH, Watson MA, Matsukuma KE, Walczak R, Collins JL, Osborne TF, Tontonoz P: Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J Biol Chem 277:11019-11025, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 11019-11025
-
-
Joseph, S.B.1
Laffitte, B.A.2
Patel, P.H.3
Watson, M.A.4
Matsukuma, K.E.5
Walczak, R.6
Collins, J.L.7
Osborne, T.F.8
Tontonoz, P.9
-
17
-
-
0035847041
-
Thyroid hormone stimulates acetyl-coA carboxylase-alpha transcription in hepatocytes by modulating the composition of nuclear receptor complexes bound to a thyroid hormone response element
-
Zhang Y, Yin L, Hillgartner FB: Thyroid hormone stimulates acetyl-coA carboxylase-alpha transcription in hepatocytes by modulating the composition of nuclear receptor complexes bound to a thyroid hormone response element. J Biol Chem 276:974-983, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 974-983
-
-
Zhang, Y.1
Yin, L.2
Hillgartner, F.B.3
-
18
-
-
0037593946
-
The transcription factor SREBP-1c is instrumental in the development of beta-cell dysfunction
-
Wang H, Maechler P, Antinozzi PA, Herrero L, Hagenfeldt-Johansson KA, Bjorklund A, Wollheim CB: The transcription factor SREBP-1c is instrumental in the development of beta-cell dysfunction. J Biol Chem 278:16622-16629, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 16622-16629
-
-
Wang, H.1
Maechler, P.2
Antinozzi, P.A.3
Herrero, L.4
Hagenfeldt-Johansson, K.A.5
Bjorklund, A.6
Wollheim, C.B.7
-
19
-
-
0037183561
-
Accumulation of foam cells in liver X receptor-deficient mice
-
Schuster GU, Parini P, Wang L, Alberti S, Steffensen KR, Hansson GK, Angelin B, Gustafsson JÅ: Accumulation of foam cells in liver X receptor-deficient mice. Circulation 106:1147-1153, 2002
-
(2002)
Circulation
, vol.106
, pp. 1147-1153
-
-
Schuster, G.U.1
Parini, P.2
Wang, L.3
Alberti, S.4
Steffensen, K.R.5
Hansson, G.K.6
Angelin, B.7
Gustafsson, J.Å.8
-
20
-
-
0034669171
-
Role of LXRs in control of lipogenesis
-
Schultz JR, Tu H, Luk A, Repa JJ, Medina JC, Li L, Schwendner S, Wang S, Thoolen M, Mangelsdorf DJ, Lustig KD, Shan B: Role of LXRs in control of lipogenesis. Genes Dev 14:2831-2838, 2000
-
(2000)
Genes Dev
, vol.14
, pp. 2831-2838
-
-
Schultz, J.R.1
Tu, H.2
Luk, A.3
Repa, J.J.4
Medina, J.C.5
Li, L.6
Schwendner, S.7
Wang, S.8
Thoolen, M.9
Mangelsdorf, D.J.10
Lustig, K.D.11
Shan, B.12
-
21
-
-
0037237779
-
Regulation of the angiopoietin-like protein 3 gene by LXR
-
Kaplan R, Zhang T, Hernandez M, Gan FX, Wright SD, Waters MG, Cai TQ: Regulation of the angiopoietin-like protein 3 gene by LXR. J Lipid Res 44:136-143, 2003
-
(2003)
J Lipid Res
, vol.44
, pp. 136-143
-
-
Kaplan, R.1
Zhang, T.2
Hernandez, M.3
Gan, F.X.4
Wright, S.D.5
Waters, M.G.6
Cai, T.Q.7
-
22
-
-
0036478902
-
Angptl3 regulates lipid metabolism in mice
-
Koishi R, Ando Y, Ono M, Shimamura M, Yasumo H, Fujiwara T, Horikoshi H, Furukawa H: Angptl3 regulates lipid metabolism in mice. Nat Genet 30:151-157, 2002
-
(2002)
Nat Genet
, vol.30
, pp. 151-157
-
-
Koishi, R.1
Ando, Y.2
Ono, M.3
Shimamura, M.4
Yasumo, H.5
Fujiwara, T.6
Horikoshi, H.7
Furukawa, H.8
-
23
-
-
0037174854
-
Regulation of cholesterol homeostasis and lipid metabolism in skeletal muscle by liver X receptors
-
Muscat GE, Wagner BL, Hou J, Tangirala RK, Bischoff ED, Rohde P, Petrowski M, Li J, Shao G, Macondray G, Schulman IG: Regulation of cholesterol homeostasis and lipid metabolism in skeletal muscle by liver X receptors. J Biol Chem 277:40722-40728, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 40722-40728
-
-
Muscat, G.E.1
Wagner, B.L.2
Hou, J.3
Tangirala, R.K.4
Bischoff, E.D.5
Rohde, P.6
Petrowski, M.7
Li, J.8
Shao, G.9
Macondray, G.10
Schulman, I.G.11
-
24
-
-
0036896653
-
Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue
-
Stulnig TM, Steffensen KR, Gao H, Reimers M, Dahlman-Wright K, Schuster GU, Gustafsson JÅ: Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue. Mol Pharmacol 62:1299-1305, 2002
-
(2002)
Mol Pharmacol
, vol.62
, pp. 1299-1305
-
-
Stulnig, T.M.1
Steffensen, K.R.2
Gao, H.3
Reimers, M.4
Dahlman-Wright, K.5
Schuster, G.U.6
Gustafsson, J.Å.7
-
25
-
-
0036312119
-
Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity
-
Stulnig TM, Oppermann U, Steffensen KR, Schuster GU, Gustafsson JÅ: Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity. Diabetes 51:2426-2433, 2002
-
(2002)
Diabetes
, vol.51
, pp. 2426-2433
-
-
Stulnig, T.M.1
Oppermann, U.2
Steffensen, K.R.3
Schuster, G.U.4
Gustafsson, J.Å.5
-
26
-
-
0037428442
-
Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis
-
Cao G, Liang Y, Broderick CL, Oldham BA, Beyer TP, Schmidt RJ, Zhang Y, Stayrook KR, Suen C, Otto KA, Miller AR, Dai J, Foxworthy P, Gao H, Ryan TP, Jiang XC, Burris TP, Eacho PI, Etgen GJ: Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis. J Biol Chem 278:1131-1136, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 1131-1136
-
-
Cao, G.1
Liang, Y.2
Broderick, C.L.3
Oldham, B.A.4
Beyer, T.P.5
Schmidt, R.J.6
Zhang, Y.7
Stayrook, K.R.8
Suen, C.9
Otto, K.A.10
Miller, A.R.11
Dai, J.12
Foxworthy, P.13
Gao, H.14
Ryan, T.P.15
Jiang, X.C.16
Burris, T.P.17
Eacho, P.I.18
Etgen, G.J.19
-
27
-
-
0036318980
-
Microarray analyses during adipogenesis: Understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism
-
Ross SE, Erickson RL, Gerin I, DeRose PM, Bajnok L, Longo KA, Misek DE, Kuick R, Hanash SM, Atkins KB, Andresen SM, Nebb HI, Madsen L, Kristiansen K, MacDougald OA: Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism. Mol Cell Biol 22:5989-5999, 2002
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5989-5999
-
-
Ross, S.E.1
Erickson, R.L.2
Gerin, I.3
DeRose, P.M.4
Bajnok, L.5
Longo, K.A.6
Misek, D.E.7
Kuick, R.8
Hanash, S.M.9
Atkins, K.B.10
Andresen, S.M.11
Nebb, H.I.12
Madsen, L.13
Kristiansen, K.14
MacDougald, O.A.15
-
28
-
-
0034611675
-
Obesity in the new millennium
-
Friedman JM: Obesity in the new millennium. Nature 404:632-634, 2000
-
(2000)
Nature
, vol.404
, pp. 632-634
-
-
Friedman, J.M.1
-
29
-
-
0034611678
-
Towards a molecular understanding of adaptive thermogenesis
-
Lowell BB, Spiegelman BM: Towards a molecular understanding of adaptive thermogenesis. Nature 404:652-660, 2000
-
(2000)
Nature
, vol.404
, pp. 652-660
-
-
Lowell, B.B.1
Spiegelman, B.M.2
-
30
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman PG: Obesity as a medical problem. Nature 404:635-643, 2000
-
(2000)
Nature
, vol.404
, pp. 635-643
-
-
Kopelman, P.G.1
-
31
-
-
0027288233
-
Glucocorticoids regulate the induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes
-
Friedman JE, Yun JS, Patel YM, McGrane MM, Hanson RW: Glucocorticoids regulate the induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes. J Biol Chem 268:12952-12957, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 12952-12957
-
-
Friedman, J.E.1
Yun, J.S.2
Patel, Y.M.3
McGrane, M.M.4
Hanson, R.W.5
-
32
-
-
0034463972
-
Understanding the role of glucocorticoids in obesity: Tissue-specific alterations of corticosterone metabolism in obese Zucker rats
-
Livingstone DE, Jones GC, Smith K, Jamieson PM, Andrew R, Kenyon CJ, Walker BR: Understanding the role of glucocorticoids in obesity: tissue-specific alterations of corticosterone metabolism in obese Zucker rats. Endocrinology 141:560-563, 2000
-
(2000)
Endocrinology
, vol.141
, pp. 560-563
-
-
Livingstone, D.E.1
Jones, G.C.2
Smith, K.3
Jamieson, P.M.4
Andrew, R.5
Kenyon, C.J.6
Walker, B.R.7
-
33
-
-
0037374775
-
Is 11beta-hydroxysteroid dehydrogenase type 1 a therapeutic target? Effects of carbenoxolone in lean and obese Zucker rats
-
Livingstone DE, Walker BR: Is 11beta-hydroxysteroid dehydrogenase type 1 a therapeutic target? Effects of carbenoxolone in lean and obese Zucker rats. J Pharmacol Exp Ther 305:167-172, 2003
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 167-172
-
-
Livingstone, D.E.1
Walker, B.R.2
-
34
-
-
0029954214
-
Insulin-dependent diabetes mellitus
-
Tisch R, McDevitt H: Insulin-dependent diabetes mellitus. Cell 85:291-297, 1996
-
(1996)
Cell
, vol.85
, pp. 291-297
-
-
Tisch, R.1
McDevitt, H.2
-
35
-
-
0036727396
-
Inflammatory status and insulin resistance
-
Grimble RF: Inflammatory status and insulin resistance. Curr Opin Clin Nutr Metab Care 5:551-559, 2002
-
(2002)
Curr Opin Clin Nutr Metab Care
, vol.5
, pp. 551-559
-
-
Grimble, R.F.1
-
36
-
-
0037085365
-
Oxysterol activators of liver X receptor and 9-cis-retinoic acid promote sequential steps in the synthesis and secretion of tumor necrosis factor-alpha from human monocytes
-
Landis MS, Patel HV, Capone JP: Oxysterol activators of liver X receptor and 9-cis-retinoic acid promote sequential steps in the synthesis and secretion of tumor necrosis factor-alpha from human monocytes. J Biol Chem 277:4713-4721, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 4713-4721
-
-
Landis, M.S.1
Patel, H.V.2
Capone, J.P.3
-
37
-
-
0037324340
-
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
-
Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P: Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med 9:213-219, 2003
-
(2003)
Nat Med
, vol.9
, pp. 213-219
-
-
Joseph, S.B.1
Castrillo, A.2
Laffitte, B.A.3
Mangelsdorf, D.J.4
Tontonoz, P.5
-
38
-
-
0034470239
-
Nitric oxide production by adipocytes: A role in the pathogenesis of insulin resistance?
-
Pilon G, Penfornis P, Marette A: Nitric oxide production by adipocytes: a role in the pathogenesis of insulin resistance? Horm Metab Res 32:480-484, 2000
-
(2000)
Horm Metab Res
, vol.32
, pp. 480-484
-
-
Pilon, G.1
Penfornis, P.2
Marette, A.3
-
39
-
-
0034682447
-
LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression
-
Tamura K, Chen YE, Horiuchi M, Chen Q, Daviet L, Yang Z, Lopez-Ilasaca M, Mu H, Pratt RE, Dzau VJ: LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression. Proc Natl Acad Sci U S A 97:8513-8518, 2000
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 8513-8518
-
-
Tamura, K.1
Chen, Y.E.2
Horiuchi, M.3
Chen, Q.4
Daviet, L.5
Yang, Z.6
Lopez-Ilasaca, M.7
Mu, H.8
Pratt, R.E.9
Dzau, V.J.10
-
40
-
-
0038012478
-
Identification of a novel set of genes regulated by a unique liver X receptor-alpha-mediated transcription mechanism
-
Anderson LM, Choe SE, Yukhananov RY, Hopfner RL, Church GM, Pratt RE, Dzau VJ: Identification of a novel set of genes regulated by a unique liver X receptor-alpha-mediated transcription mechanism. J Biol Chem 278:15252-15260, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 15252-15260
-
-
Anderson, L.M.1
Choe, S.E.2
Yukhananov, R.Y.3
Hopfner, R.L.4
Church, G.M.5
Pratt, R.E.6
Dzau, V.J.7
-
41
-
-
0037184935
-
Regulation of ALK-1 signaling by the nuclear receptor LXRbeta
-
Mo J, Fang SJ, Chen W, Blobe GC: Regulation of ALK-1 signaling by the nuclear receptor LXRbeta. J Biol Chem 277:50788-50794, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 50788-50794
-
-
Mo, J.1
Fang, S.J.2
Chen, W.3
Blobe, G.C.4
-
42
-
-
0037340125
-
Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-(alpha)
-
Goodwin B, Watson MA, Kim H, Miao J, Kemper JK, Kliewer SA: Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-(alpha). Mol Endocrinol 17:386-394, 2003
-
(2003)
Mol Endocrinol
, vol.17
, pp. 386-394
-
-
Goodwin, B.1
Watson, M.A.2
Kim, H.3
Miao, J.4
Kemper, J.K.5
Kliewer, S.A.6
-
43
-
-
14444285707
-
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
-
Lehmann JM, Kliewer SA, Moore LB, Smith-Oliver TA, Oliver BB, Su JL, Sundseth SS, Winegar DA, Blanchard DE, Spencer TA, Willson TM: Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. J Biol Chem 272:3137-3140, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 3137-3140
-
-
Lehmann, J.M.1
Kliewer, S.A.2
Moore, L.B.3
Smith-Oliver, T.A.4
Oliver, B.B.5
Su, J.L.6
Sundseth, S.S.7
Winegar, D.A.8
Blanchard, D.E.9
Spencer, T.A.10
Willson, T.M.11
-
44
-
-
0033997752
-
Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element
-
Luo Y, Tall AR: Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element. J Clin Invest 105:513-520, 2000
-
(2000)
J Clin Invest
, vol.105
, pp. 513-520
-
-
Luo, Y.1
Tall, A.R.2
-
45
-
-
0034284918
-
Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
-
Repa JJ, Turley SD, Lobaccaro JA, Medina J, Li L, Lustig K, Shan B, Heyman RA, Dietschy JM, Mangelsdorf DJ: Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers. Science 289:1524-1529, 2000
-
(2000)
Science
, vol.289
, pp. 1524-1529
-
-
Repa, J.J.1
Turley, S.D.2
Lobaccaro, J.A.3
Medina, J.4
Li, L.5
Lustig, K.6
Shan, B.7
Heyman, R.A.8
Dietschy, J.M.9
Mangelsdorf, D.J.10
-
46
-
-
0034710965
-
Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha
-
Venkateswaran A, Laffitte BA, Joseph SB, Mak PA, Wilpitz DC, Edwards PA, Tontonoz P: Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha. Proc Natl Acad Sci U S A 97:12097-12102, 2000
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12097-12102
-
-
Venkateswaran, A.1
Laffitte, B.A.2
Joseph, S.B.3
Mak, P.A.4
Wilpitz, D.C.5
Edwards, P.A.6
Tontonoz, P.7
-
47
-
-
0038614979
-
Stimulation of cholesterol excretion by LXR agonist requires ATP-binding cassette transporters G5 and G8
-
Yu L, York J, Bergmann Kv K, Lutjohann D, Cohen JC, Hobbs HH: Stimulation of cholesterol excretion by LXR agonist requires ATP-binding cassette transporters G5 and G8. J Biol Chem 278:15565-15570, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 15565-15570
-
-
Yu, L.1
York, J.2
Bergmann, K.V.K.3
Lutjohann, D.4
Cohen, J.C.5
Hobbs, H.H.6
-
48
-
-
0035852770
-
Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands
-
DeBose-Boyd RA, Ou J, Goldstein JL, Brown MS: Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands. Proc Natl Acad Sci U S A 98:1477-1482, 2001
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 1477-1482
-
-
DeBose-Boyd, R.A.1
Ou, J.2
Goldstein, J.L.3
Brown, M.S.4
-
49
-
-
0035941285
-
Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages
-
Whitney KD, Watson MA, Goodwin B, Galardi CM, Maglich JM, Wilson JG, Willson TM, Collins JL, Kliewer SA: Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages. J Biol Chem 276:43509-43515, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 43509-43515
-
-
Whitney, K.D.1
Watson, M.A.2
Goodwin, B.3
Galardi, C.M.4
Maglich, J.M.5
Wilson, J.G.6
Willson, T.M.7
Collins, J.L.8
Kliewer, S.A.9
-
50
-
-
0036188910
-
Induction of human liver X receptor alpha gene expression via an autoregulatory loop mechanism
-
Li Y, Bolten C, Bhat BG, Woodring-Dietz J, Li S, Prayaga SK, Xia C, Lala DS: Induction of human liver X receptor alpha gene expression via an autoregulatory loop mechanism. Mol Endocrinol 16:506-514, 2002
-
(2002)
Mol Endocrinol
, vol.16
, pp. 506-514
-
-
Li, Y.1
Bolten, C.2
Bhat, B.G.3
Woodring-Dietz, J.4
Li, S.5
Prayaga, S.K.6
Xia, C.7
Lala, D.S.8
-
51
-
-
0035900749
-
Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta
-
Zhang Y, Repa JJ, Gauthier K, Mangelsdorf DJ: Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta. J Biol Chem 276:43018-43024, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 43018-43024
-
-
Zhang, Y.1
Repa, J.J.2
Gauthier, K.3
Mangelsdorf, D.J.4
-
52
-
-
0037131347
-
Phospholipid transfer protein is regulated by liver X receptors in vivo
-
Cao G, Beyer TP, Yang XP, Schmidt RJ, Zhang Y, Bensch WR, Kauffman RF, Gao H, Ryan TP, Liang Y, Eacho PI, Jiang XC: Phospholipid transfer protein is regulated by liver X receptors in vivo. J Biol Chem 277:39561-39565, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 39561-39565
-
-
Cao, G.1
Beyer, T.P.2
Yang, X.P.3
Schmidt, R.J.4
Zhang, Y.5
Bensch, W.R.6
Kauffman, R.F.7
Gao, H.8
Ryan, T.P.9
Liang, Y.10
Eacho, P.I.11
Jiang, X.C.12
-
53
-
-
0038542910
-
Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes
-
Malerod L, Juvet LK, Hanssen-Bauer A, Eskild W, Berg T: Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes. Biochem Biophys Res Commun 299:916-923, 2002
-
(2002)
Biochem Biophys Res Commun
, vol.299
, pp. 916-923
-
-
Malerod, L.1
Juvet, L.K.2
Hanssen-Bauer, A.3
Eskild, W.4
Berg, T.5
-
54
-
-
0037289786
-
Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: Liver-X-receptor-specific inhibition of inflammation and primary cytokine production
-
Fowler AJ, Sheu MY, Schmuth M, Kao J, Fluhr JW, Rhein L, Collins JL, Willson TM, Mangelsdorf DJ, Elias PM, Feingold KR: Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production. J Invest Dermatol 120:246-255, 2003
-
(2003)
J Invest Dermatol
, vol.120
, pp. 246-255
-
-
Fowler, A.J.1
Sheu, M.Y.2
Schmuth, M.3
Kao, J.4
Fluhr, J.W.5
Rhein, L.6
Collins, J.L.7
Willson, T.M.8
Mangelsdorf, D.J.9
Elias, P.M.10
Feingold, K.R.11
|