Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning

Journal of Biological Chemistry

Volumn 273, Issue 28, 1998, Pages 17801-17809

  Duncan, Elizabeth A ^a   Davé, Utpal P ^a   Sakai, Juro ^a   Goldstein, Joseph L ^a   Brown, Michael S ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYSTEINE; DNA BINDING PROTEIN; HYBRID PROTEIN; STEROL;

ARTICLE; CELL MEMBRANE; HUMAN; HUMAN CELL; MEMBRANE BINDING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; TECHNIQUE;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL MEMBRANE; CHEMILUMINESCENT MEASUREMENTS; CHO CELLS; CRICETINAE; CYSTEINE; DNA-BINDING PROTEINS; HUMANS; HYDROLYSIS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION FACTORS;

EID: 0032504202     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.28.17801     Document Type: Article

References (30)

1. Brown, M. S., and Goldstein, J. L. (1997) Cell 89, 331-340
2. Kim, J. B., and Spiegelman, B. M. (1996) Genes Dev. 10, 1096-1107
3. Ericsson, J., Jackson, S. M., Lee, B. C., and Edwards, P. A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 945-950
4. Guan, G., Jiang, G., Koch, R. L., and Shechter, I. (1995) J. Biol. Chem. 270, 21958-21965
5. Vallett, S. M., Sanchez, H. B., Rosenfeld, J. M., and Osborne, T. F. (1996) J. Biol. Chem. 271, 12247-12253
6. Bennett, M. K., Lopez, J. M., Sanchez, H. B., and Osbrone, T. F. (1995) J. Biol. Chem. 270, 25578-25583
7. Shimano, H., Horton, J. D., Hammer, R. E., Shimomura, I., Brown, M. S., and Goldstein, J. L. (1996) J. Clin. Invest. 98, 1575-1584
8. Ericsson, J., Jackson, S. M., Kim, J. B., Spiegelman, B. M., and Edwards, P. A. (1997) J. Biol. Chem. 272, 7298-7305
9. Hua, X., Sakai, J., Ho, Y. K., Goldstein, J. L., and Brown, M. S. (1995) J. Biol. Chem. 270, 29422-29427
10. Sakai, J., Nohturfft, A., Cheng, D., Ho, Y. K., Brown, M. S., and Goldstein, J. L. (1997) J. Biol. Chem. 272, 20213-20221
11. Sakai, J., Nohturfft, A., Goldstein, J. L., and Brown, M. S. (1998) J. Biol. Chem. 273, 5785-5793
12. Sakai, J., Duncan, E. A., Rawson, R. B., Hua, X., Brown, M. S., and Goldstein, J. L. (1996) Cell 85, 1037-1046
13. Hua, X., Nohturfft, A., Goldstein, J. L., and Brown, M. S. (1996) Cell 87, 415-426
14. Duncan, E. A., Brown, M. S., Goldstein, J. L., and Sakai, J. (1997) J. Biol. Chem. 272, 12778-12785
15. Rawson, R. B., Zelenski, N. G., Nijhawan, D., Ye, J., Sakai, J., Hasan, M. T., Chang, T.-Y., Brown, M. S., and Goldstein, J. L. (1997) Molecular Cell 1, 47-57
16. Hasan, M. T., Chang, C. C. Y., and Chang, T. Y. (1994) Somatic Cell Mol. Genet. 20, 183-194
17. Hua, X., Sakai, J., Brown, M. S., and Goldstein, J. L. (1996) J. Biol. Chem. 271, 10379-10384
18. Mocchetti, I., Einstein, R., and Brosius, J. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 7221-7225
19. Hua, X., Yokoyama, C., Wu, J., Briggs, M. R., Brown, M. S., Goldstein, J. L., and Wang, X. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 11603-11607
20. Gil, G., Faust, J. R., Chin, D. J., Goldstein, J. L., and Brown, M. S. (1985) Cell 41, 249-258
21. Bollag, D. M., and Edelstein, S. J. (1991) Protein Methods, p. 100, Wiley-Liss, Inc. New York, NY
22. Schägger, H., and von Jagow, G. (1987) Anal. Biochem. 166, 368-379
23. Akusjärvi, G., Svensson, C., and Nygard, O. (1987) Mol. Cell. Biol. 7, 549-551
24. Isola, V. J., Eisenberg, R. J., Siebert, G. R., Heilman, C. J., Wilcox, W. C., and Cohen, G. H. (1989) J. Virol. 63, 2325-2334
25. Sato, R., Yang, J., Wang, X., Evans, M. J., Ho, Y. K., Goldstein, J. L., and Brown, M. S. (1994) J. Biol. Chem. 269, 17267-17273
26. Yang, J., Sato, R., Goldstein, J. L., and Brown, M. S. (1994) Genes Dev. 8, 1910-1919
27. Tontonoz, P., Kim, J. B., Graves, R. A., and Spiegelman, B. M. (1993) Mol. Cell. Biol. 13, 4753-4759
28. Theopold, U., Ekengren, S., and Hultmark, D. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 1195-1199
29. Deisenhofer, J., and Michel, H. (1989) Chem. Scr. 29, 205-220
30. Selkoe, D. J. (1996) J. Biol. Chem. 271, 18295-19298