Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins

Journal of Biological Chemistry

Volumn 274, Issue 32, 1999, Pages 22795-22804

  Espenshade, Peter J ^a   Cheng, Dong ^a   Goldstein, Joseph L ^a   Brown, Michael S ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; COMPLEMENTARY DNA; PROTEIN PRECURSOR; PROTEINASE; RECOMBINANT PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN; SUBTILISIN;

AMINO ACID SEQUENCE; ARTICLE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; ANIMALS; CHOLESTEROL; CRICETINAE; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HYDROXYCHOLESTEROLS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PRECIPITIN TESTS; PROPROTEIN CONVERTASES; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-MYC; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; SPECIES SPECIFICITY; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION FACTORS;

CRICETINAE; STAPHYLOCOCCUS PHAGE 187;

EID: 0033529560     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.32.22795     Document Type: Article

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