Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain

Journal of Biological Chemistry

Volumn 273, Issue 27, 1998, Pages 17243-17250

  Nohturfft, Axel ^a   Brown, Michael S ^a   Goldstein, Joseph L ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MEMBRANE PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN GLYCOSYLATION; STEROL SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; CHO CELLS; CRICETINAE; GLYCOSYLATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; PROTEIN CONFORMATION; STEROLS;

EID: 0032479439     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.27.17243     Document Type: Article

References (37)

1. Brown, M. S., and Goldstein, J. L. (1997) Cell 89, 331-340
2. Sakai, J., Nohturfft, A., Cheng, D., Ho, Y. K., Brown, M. S., and Goldstein, J. L. (1997) J. Biol. Chem. 272, 20213-20221
3. Sakai, J., Nohturfft, A., Goldstein, J. L., and Brown, M. S. (1998) J. Biol. Chem. 273, 5785-5793
4. Hua, X., Sakai, J., Ho, Y. K., Goldstein, J. L., and Brown, M. S. (1995) J. Biol. Chem. 270, 29422-29427
5. Duncan, E. A., Brown, M. S., Goldstein, J. L., and Sakai, J. (1997) J. Biol. Chem. 272, 12778-12785
6. Rawson, R. B., Zelenski, N. G., Nijhawan, D., Ye, J., Sakai, J., Hasan, M. T., Chang, T.-Y., Brown, M. S., and Goldstein, J. L. (1997) Molecular Cell 1, 47-57
7. Hua, X., Nohturfft, A., Goldstein, J. L., and Brown, M. S. (1996) Cell 87, 415-426
8. Loftus, S. K, Morris, J. A., Carstea, E. D., Gu, J. Z., Cummings, C., Brown, A., Ellison, J., Ohno, K., Rosenfeld, M. A., Tagle, D. A., Pentchev, P. G., and Pavan, W. J. (1997) Science 277, 232-235
9. Kim, J. B., and Spiegelman, B. M. (1996) Genes Dev. 10, 1096-1107
10. Ericsson, J., Jackson, S. M., Lee, B. C., and Edwards, P. A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 945-950
11. Lopez, J. M., Bennett, M. K., Sanchez, H. B., Rosenfeld, J. M., and Osborne, T. F. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 1049-1053
12. Osborne, T. F. (1995) Crit. Rev. Eukaryotic Gene Expression 5, 317-335
13. Ericsson, J., Jackson, S. M., Kim, J. B., Spiegelman, B. M., and Edwards, P. A. (1997) J. Biol. Chem. 272, 7298-7305
14. Neer, E. J., Schmidt, C. J., Nambudripad, R., and Smith, T. F. (1994) Nature 371, 297-300
15. Wall, M. A., Coleman, D. E., Lee, E., Iniguez-Lluhi, J. A., Posner, B. A., Gilman, A. G., and Sprang, S. R. (1995) Cell 83, 1047-1058
16. Lambright, D. G., Sondek, J., Bohm, A., Skiba, N. P., Hamm, H. E., and Sigler, P. B. (1996) Nature 379, 311-319
17. Liscum, L., Finer-Moore, J., Stroud, R. M., Luskey, K. L., Brown, M. S., and Goldstein, J. L. (1985) J. Biol. Chem. 260, 522-530
18. Olender, E. H., and Simoni, R. D. (1992) J. Biol. Chem. 267, 4223-4235
19. Metherall, J. E., Goldstein, J. L., Luskey, K. L., and Brown, M. S. (1989) J. Biol. Chem. 264, 15634-15641
20. Hua, X., Sakai, J., Brown, M. S., and Goldstein, J. L. (1996) J. Biol. Chem. 271, 10379-10384
21. Wang, X., Sato, R., Brown, M. S., Hua, X., and Goldstein, J. L. (1994) Cell 77, 53-62
22. Isola, V. J., Eisenberg, R. J., Siebert, G. R., Heilman, C. J., Wilcox, W. C., and Cohen, G. H. (1989) J. Virol. 63, 2325-2334
23. Yamamoto, T., Davis, C. G., Brown, M. S., Schneider, W. J., Casey, M. L., Goldstein, J. L., and Russell, D. W. (1984) Cell 39, 27-38
24. Nelson, R. M., and Long, G. L. (1989) Anal. Biochem. 180, 147-151
25. Roitelman, J., Olender, E. H., Bar-Nun, S., Dunn, W. A., Jr., and Simoni, R. D. (1992) J. Cell Biol. 117, 959-973
26. Munro, S., and Pelham, H. R. B. (1987) Cell 48, 899-907
27. Koch, G. L. E., and Macer, D. R. J. (1988) J. Cell Sci. 90, 485-491
28. Gil, G., Faust, J. R., Chin, D. J., Goldstein, J. L., and Brown, M. S. (1985) Cell 41, 249-258
29. Inoue, S., and Simoni, R. D. (1992) J. Biol. Chem. 267, 9080-9086
30. Rock, K. L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D., and Goldberg, A. L. (1994) Cell 78, 761-771
31. Nohturfft, A., Hua, X., Brown, M. S., and Goldstein, J. L. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 13709-13714
32. Pentchev, P. G., Vanier, M. T., Suzuki, K., and Patterson, M. C. (1995) The Metabolic and Molecular Basis of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., and Valle, D., eds) pp. 2625-2639, McGraw-Hill Inc. New York
33. Liscum, L., and Underwood, K. W. (1995) J. Biol. Chem. 270, 15443-15446
34. Tabin, C. J., and McMahon, A. P. (1997) Trends Cell Biol. 7, 442-446
35. Porter, J. A., Young, K. E., and Beachy, P. A. (1996) Science 274, 255-259
36. Kyte, J., and Doolittle, R. F. (1982) J. Mol. Biol. 157, 105-132
37. Sakai, J., Duncan, E. A., Rawson, R. B., Hua, X., Brown, M. S., and Goldstein, J. L. (1996) Cell 85, 1037-1046