-
1
-
-
0141720776
-
Restraining the V(D)J recombinase
-
Roth, D. B. Restraining the V(D)J recombinase. Nature Rev. Immunol. 3, 656-666 (2003).
-
(2003)
Nature Rev. Immunol
, vol.3
, pp. 656-666
-
-
Roth, D.B.1
-
2
-
-
0023026643
-
Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency
-
Schuler, W. et al. Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency. Cell 46, 963-972 (1986).
-
(1986)
Cell
, vol.46
, pp. 963-972
-
-
Schuler, W.1
-
3
-
-
0030837472
-
(D)J recombination in Ku86-deficient mice: Distinct effects on coding, signal, and hybrid joint formation
-
Bogue, M. A., Wang, C., Zhu, C. & Roth, D. B. V. (D)J recombination in Ku86-deficient mice: Distinct effects on coding, signal, and hybrid joint formation. Immunity 7, 37-47 (1997).
-
(1997)
Immunity
, vol.7
, pp. 37-47
-
-
Bogue, M.A.1
Wang, C.2
Zhu, C.3
Roth, D.B.V.4
-
4
-
-
0032417640
-
A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis
-
Gao, Y. et al. A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell 95, 891-902 (1998).
-
(1998)
Cell
, vol.95
, pp. 891-902
-
-
Gao, Y.1
-
5
-
-
0037188898
-
Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations
-
Zhu, C. et al. Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell 109, 811-821 (2002).
-
(2002)
Cell
, vol.109
, pp. 811-821
-
-
Zhu, C.1
-
6
-
-
0035839840
-
DNA double strand break repair and chromosomal translocation: Lessons from animal models
-
Ferguson, D. O. & Alt, F. W. DNA double strand break repair and chromosomal translocation: lessons from animal models. Oncogene 20, 5572-5579 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 5572-5579
-
-
Ferguson, D.O.1
Alt, F.W.2
-
7
-
-
0035108439
-
Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination
-
Qiu, J. X., Kale, S. B., Yarnall Schultz, H. & Roth, D. B. Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination. Mol. Cell 7, 77-87 (2001).
-
(2001)
Mol. Cell
, vol.7
, pp. 77-87
-
-
Qiu, J.X.1
Kale, S.B.2
Yarnall Schultz, H.3
Roth, D.B.4
-
8
-
-
0035108780
-
Joining-deficient RAG1 mutants block V(D)J recombination in vivo and hairpin opening in vitro
-
Yarnall Schultz, H., Landree, M. A., Qiu, J. X., Kale, S. B. & Roth, D. B. Joining-deficient RAG1 mutants block V(D)J recombination in vivo and hairpin opening in vitro. Mol. Cell 7, 65-75 (2001).
-
(2001)
Mol. Cell
, vol.7
, pp. 65-75
-
-
Yarnall Schultz, H.1
Landree, M.A.2
Qiu, J.X.3
Kale, S.B.4
Roth, D.B.5
-
9
-
-
1942421722
-
RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination
-
Lee, G. S., Neiditch, M. B., Salus, S. S. & Roth, D. B. RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination. Cell 117, 171-184 (2004).
-
(2004)
Cell
, vol.117
, pp. 171-184
-
-
Lee, G.S.1
Neiditch, M.B.2
Salus, S.S.3
Roth, D.B.4
-
10
-
-
0028307661
-
Analysis of regions of RAG-2 important for V(D)J recombination
-
Cuomo, C. A. & Oettinger, M. A. Analysis of regions of RAG-2 important for V(D)J recombination. Nucleic Acids Res. 22, 1810-1814 (1994).
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 1810-1814
-
-
Cuomo, C.A.1
Oettinger, M.A.2
-
11
-
-
0028237683
-
Definition of a core region of RAG-2 that is functional in V(D)J recombination
-
Sadofsky, M. J., Hesse, J. E. & Gellert, M. Definition of a core region of RAG-2 that is functional in V(D)J recombination. Nucleic Acids Res. 22, 1805-1809 (1994).
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 1805-1809
-
-
Sadofsky, M.J.1
Hesse, J.E.2
Gellert, M.3
-
12
-
-
0033380368
-
Mutational analysis of RAG-1 and RAG-2 identifies three active site amino acids in RAG-1 critical for both cleavage steps of V(D)J recombination
-
Landree, M. A., Wibbenmeyer, J. A. & Roth, D. B. Mutational analysis of RAG-1 and RAG-2 identifies three active site amino acids in RAG-1 critical for both cleavage steps of V(D)J recombination. Genes Dev. 13, 3059-3069 (1999).
-
(1999)
Genes Dev
, vol.13
, pp. 3059-3069
-
-
Landree, M.A.1
Wibbenmeyer, J.A.2
Roth, D.B.3
-
13
-
-
0022976432
-
Nonhomologous recombination in mammalian cells: Role for short sequence homologies in the joining reaction
-
Roth, D. B. & Wilson, J. H. Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction. Mol. Cell. Biol. 6, 4295-4304 (1986).
-
(1986)
Mol. Cell. Biol
, vol.6
, pp. 4295-4304
-
-
Roth, D.B.1
Wilson, J.H.2
-
14
-
-
0032404178
-
Double-strand break repair in Ku86- and XRCC4-deficient cells
-
Kabotyanski, E. B., Gomelsky, L., Han, J.-O., Stamato, T. D. & Roth, D. B. Double-strand break repair in Ku86- and XRCC4-deficient cells. Nucleic Acids Res. 26, 5333-5342 (1998).
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 5333-5342
-
-
Kabotyanski, E.B.1
Gomelsky, L.2
Han, J.-O.3
Stamato, T.D.4
Roth, D.B.5
-
15
-
-
0036206462
-
Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells
-
Verkaik, N. S. et al. Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells. Eur. J. Immunol. 32, 701-709 (2002).
-
(2002)
Eur. J. Immunol
, vol.32
, pp. 701-709
-
-
Verkaik, N.S.1
-
16
-
-
0043133778
-
Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair
-
Ding, Q. et al. Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair. Mol. Cell. Biol. 23, 5836-5848 (2003).
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 5836-5848
-
-
Ding, Q.1
-
17
-
-
0029585872
-
The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination
-
Li, Z. et al. The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell 83, 1079-1089 (1995).
-
(1995)
Cell
, vol.83
, pp. 1079-1089
-
-
Li, Z.1
-
18
-
-
0027770854
-
Expression and V(D)J recombination activity of mutated RAG-1 proteins
-
Sadofsky, M. J., Hesse, J. E., McBlane, J. F. & Gellert, M. Expression and V(D)J recombination activity of mutated RAG-1 proteins. Nucleic Acids Res. 21, 5644-5650 (1993).
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 5644-5650
-
-
Sadofsky, M.J.1
Hesse, J.E.2
McBlane, J.F.3
Gellert, M.4
-
19
-
-
0029917808
-
Regions of RAG1 protein critical for V(D)J recombination
-
Kirch, S. A., Sudarsanam, P. & Oettinger, M. A. Regions of RAG1 protein critical for V(D)J recombination. Eur. J. Immunol. 26, 886-891 (1996).
-
(1996)
Eur. J. Immunol
, vol.26
, pp. 886-891
-
-
Kirch, S.A.1
Sudarsanam, P.2
Oettinger, M.A.3
-
20
-
-
34748863465
-
IgH class switching and translocations use a robust non-classical end-joining pathway
-
doi:10.1038/nature06020 this issue, published online 22 August
-
Yan, C. T. et al. IgH class switching and translocations use a robust non-classical end-joining pathway. Nature doi:10.1038/nature06020 (this issue); published online 22 August 2007.
-
(2007)
Nature
-
-
Yan, C.T.1
-
21
-
-
2442700252
-
Paradigm switching in the germinal center
-
Posey, J. E., Brandt, V. L. & Roth, D. B. Paradigm switching in the germinal center. Nature Immunol. 5, 476-477 (2004).
-
(2004)
Nature Immunol
, vol.5
, pp. 476-477
-
-
Posey, J.E.1
Brandt, V.L.2
Roth, D.B.3
-
22
-
-
4344571097
-
Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice
-
Talukder, S. R., Dudley, D. D., Alt, F. W., Takahama, Y. & Akamatsu, Y. Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice. Nucleic Acids Res. 32, 4539-4549 (2004).
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 4539-4549
-
-
Talukder, S.R.1
Dudley, D.D.2
Alt, F.W.3
Takahama, Y.4
Akamatsu, Y.5
-
23
-
-
5144225797
-
DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining
-
Bentley, J., Diggle, C. P., Harnden, P., Knowles, M. A. & Kiltie, A. E. DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining. Nucleic Acids Res. 32, 5249-5259 (2004).
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 5249-5259
-
-
Bentley, J.1
Diggle, C.P.2
Harnden, P.3
Knowles, M.A.4
Kiltie, A.E.5
-
24
-
-
33646237581
-
Mutagenicity of non-homologous end joining DNA repair in a resistant subset of human chronic lymphocytic leukaemia B cells
-
Deriano, L., Merle-Beral, H., Guipaud, O., Sabatier, L. & Delic, J. Mutagenicity of non-homologous end joining DNA repair in a resistant subset of human chronic lymphocytic leukaemia B cells. Br. J. Haematol. 133, 520-525 (2006).
-
(2006)
Br. J. Haematol
, vol.133
, pp. 520-525
-
-
Deriano, L.1
Merle-Beral, H.2
Guipaud, O.3
Sabatier, L.4
Delic, J.5
-
25
-
-
0023801238
-
The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination
-
Lieber, M. R. et al. The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination. Cell 55, 7-16 (1988).
-
(1988)
Cell
, vol.55
, pp. 7-16
-
-
Lieber, M.R.1
|