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Volumn 16, Issue 15, 1997, Pages 4788-4795

Identification of saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair

Author keywords

DNA ligase; DNA repair; Double strand break repair; Ku; Radiosensitivity

Indexed keywords

DNA BINDING PROTEIN; DOUBLE STRANDED DNA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RESTRICTION ENDONUCLEASE; SINGLE STRANDED DNA;

EID: 0030849085     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.15.4788     Document Type: Article
Times cited : (237)

References (49)
  • 1
    • 0023019231 scopus 로고
    • Different substrate specificities of the two DNA ligases of mammalian cells
    • Arrand, J.E., Willis, A.E., Goldsmith, I. and Lindahl, T. (1986) Different substrate specificities of the two DNA ligases of mammalian cells. J. Biol. Chem., 261, 9079-9082.
    • (1986) J. Biol. Chem. , vol.261 , pp. 9079-9082
    • Arrand, J.E.1    Willis, A.E.2    Goldsmith, I.3    Lindahl, T.4
  • 3
    • 0026680743 scopus 로고
    • Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA damaging agents
    • Barnes, D.E., Tomkinson, A.E., Lehmann, A.R., Webster, A.D.B. and Lindahl, T. (1992) Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA damaging agents. Cell, 69, 495-503.
    • (1992) Cell , vol.69 , pp. 495-503
    • Barnes, D.E.1    Tomkinson, A.E.2    Lehmann, A.R.3    Webster, A.D.B.4    Lindahl, T.5
  • 4
    • 0025731583 scopus 로고
    • Structure and function of telomeres
    • Blackburn, E.H. (1991) Structure and function of telomeres. Nature, 350, 569-573.
    • (1991) Nature , vol.350 , pp. 569-573
    • Blackburn, E.H.1
  • 5
    • 0029791694 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Ku70 potentiates illegitimate DNa double strand break repair and serves as a barrier to error prone DNa repair pathways
    • Boulton, S.J. and Jackson, S.P. (1996a) Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double strand break repair and serves as a barrier to error prone DNA repair pathways. EMBO J., 15, 5093-5103.
    • (1996) EMBO J. , vol.15 , pp. 5093-5103
    • Boulton, S.J.1    Jackson, S.P.2
  • 6
    • 0029843408 scopus 로고    scopus 로고
    • Identification of a Saccharomyces cerevisiae Ku80 homologue: Roles in DNa double strand break rejoining and in telomeric maintenance
    • Boulton, S.J. and Jackson, S.P. (1996b) Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res., 24, 4639-4648.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4639-4648
    • Boulton, S.J.1    Jackson, S.P.2
  • 8
    • 0031031787 scopus 로고    scopus 로고
    • From BRCA1 to RAP1: A widespread BRCT module closely associated with DNa repair
    • Callebaut, I. and Mornon, J.P. (1997) From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair. FEBS Lett., 400, 25-30.
    • (1997) FEBS Lett. , vol.400 , pp. 25-30
    • Callebaut, I.1    Mornon, J.P.2
  • 10
    • 0025091655 scopus 로고
    • A DNA ligase gene in the Copenhagen strain of vaccinia virus is non-essential for viral replication and recombination
    • Colinas, R.J., Goebel, S.J., Davi, S.W., Johnson, G.P. Norton, E.K. and Paoletti, E. (1990) A DNA ligase gene in the Copenhagen strain of vaccinia virus is non-essential for viral replication and recombination. Virology, 179, 267-275.
    • (1990) Virology , vol.179 , pp. 267-275
    • Colinas, R.J.1    Goebel, S.J.2    Davi, S.W.3    Johnson, G.P.4    Norton, E.K.5    Paoletti, E.6
  • 11
    • 0019976340 scopus 로고
    • Regulation of DNA ligase activity by poly(ADP-ribose)
    • Creissen, D. and Shall, S. (1982) Regulation of DNA ligase activity by poly(ADP-ribose). Nature, 296, 271-272.
    • (1982) Nature , vol.296 , pp. 271-272
    • Creissen, D.1    Shall, S.2
  • 12
    • 0029742576 scopus 로고    scopus 로고
    • Human Rad50 is physically associated with human Mre11-identification of a conserved multiprotein complex implicated in recombination repair
    • Dolganov, G.M., Maser, R.S., Novikov, A., Tosto, L., Chong, S., Bressan, D.A. and Petrini, J.H.J. (1996) Human Rad50 is physically associated with human Mre11-identification of a conserved multiprotein complex implicated in recombination repair. Mol. Cell. Biol., 16, 4832-4841.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4832-4841
    • Dolganov, G.M.1    Maser, R.S.2    Novikov, A.3    Tosto, L.4    Chong, S.5    Bressan, D.A.6    Petrini, J.H.J.7
  • 13
    • 0027288231 scopus 로고
    • A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae
    • Feldmann, H. and Winnacker, E.L. (1993) A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae. J. Biol. Chem., 268, 12895-12900.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12895-12900
    • Feldmann, H.1    Winnacker, E.L.2
  • 16
    • 10244239321 scopus 로고    scopus 로고
    • Life with 6000 genes
    • Goffeau, A. et al. (1996) Life with 6000 genes. Science, 274, 546.
    • (1996) Science , vol.274 , pp. 546
    • Goffeau, A.1
  • 17
    • 0021839392 scopus 로고
    • Cells from an immunodeficient patient (46BR) with a defect in DNa ligation are hypomutable but hypersensitive to the induction of sister chromatid exchanges
    • Henderson, L.M., Arlett, C.F., Harcourt, S.A., Lehmann, A.R. and Broughton, B.C. (1985) Cells from an immunodeficient patient (46BR) with a defect in DNA ligation are hypomutable but hypersensitive to the induction of sister chromatid exchanges. Proc. Natl Acad. Sci. USA, 82, 2044-2048.
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 2044-2048
    • Henderson, L.M.1    Arlett, C.F.2    Harcourt, S.A.3    Lehmann, A.R.4    Broughton, B.C.5
  • 19
    • 0028791446 scopus 로고
    • DNA double-strand break repair and V(D)J recombination: Involvement of DNA-PK
    • Jackson, S.P. and Jeggo, P.A. (1995) DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem. Sci. 20, 412-415.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 412-415
    • Jackson, S.P.1    Jeggo, P.A.2
  • 20
    • 0027320551 scopus 로고
    • A mammalian protein complex that repairs double strand breaks and deletions by recombination
    • Jessberger, R., Podust, V., Hubscher, U. and Berg, P. (1993) A mammalian protein complex that repairs double strand breaks and deletions by recombination. J. Biol. Chem., 268, 15070-15079.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15070-15079
    • Jessberger, R.1    Podust, V.2    Hubscher, U.3    Berg, P.4
  • 21
    • 0018243214 scopus 로고
    • Saccharomyces cerevisiae cell cycle mutant cdc9 is defective in DNA ligase
    • Johnston, L.H. and Nasmyth, K.A. (1978) Saccharomyces cerevisiae cell cycle mutant cdc9 is defective in DNA ligase. Nature, 274, 891-893.
    • (1978) Nature , vol.274 , pp. 891-893
    • Johnston, L.H.1    Nasmyth, K.A.2
  • 22
    • 0026061401 scopus 로고
    • Vaccinia DNA ligase complements Saccharomyces cerevisiae cdc9, localizes in cytoplasmic factories and affects virulence and virus sensitivity to DNA damaging agents
    • Kerr, S.M., Johnston, L.H., Odell, M. Duncan, S.A., Law, K.M. and Smith, G.L. (1991) Vaccinia DNA ligase complements Saccharomyces cerevisiae cdc9, localizes in cytoplasmic factories and affects virulence and virus sensitivity to DNA damaging agents. EMBO J., 10, 4343-4350.
    • (1991) EMBO J. , vol.10 , pp. 4343-4350
    • Kerr, S.M.1    Johnston, L.H.2    Odell, M.3    Duncan, S.A.4    Law, K.M.5    Smith, G.L.6
  • 24
    • 0029842307 scopus 로고    scopus 로고
    • Reconstitution of DNA base excision repair with purified human proteins: Interaction between DNA polymerase beta and the XRCC1 protein
    • Kubota, Y., Nash, R.A., Klungland, A., Schar, P., Barnes, D.E. and Lindahl, T. (1996) Reconstitution of DNA base excision repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein. EMBO J., 15, 6662-6670.
    • (1996) EMBO J. , vol.15 , pp. 6662-6670
    • Kubota, Y.1    Nash, R.A.2    Klungland, A.3    Schar, P.4    Barnes, D.E.5    Lindahl, T.6
  • 26
    • 0028361265 scopus 로고
    • DNA ligase is associated with the 21 S complex of enzymes for DNA synthesis in HeLa cells
    • Li, C.G., Goodchild, J. and Baril, E.F. (1994) DNA ligase is associated with the 21 S complex of enzymes for DNA synthesis in HeLa cells. Nucleic Acids Res., 22, 632-638.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 632-638
    • Li, C.G.1    Goodchild, J.2    Baril, E.F.3
  • 28
    • 0030297546 scopus 로고    scopus 로고
    • Telomeres and telomerase: A simple picture becomes complex
    • Lundblad, V. and Wright, W.E. (1996) Telomeres and telomerase: a simple picture becomes complex. Cell, 87, 369-375.
    • (1996) Cell , vol.87 , pp. 369-375
    • Lundblad, V.1    Wright, W.E.2
  • 29
    • 0031045858 scopus 로고    scopus 로고
    • An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNa ligase III with distinct biochemical properties that may function in meiotic recombination
    • Mackey, Z.B., Ramos, W., Levin, D.S., Walter, C.A., McCarrey, J.R. and Tomkinson, A.E. (1997) An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination. Mol. Cell. Biol. 17, 989-998.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 989-998
    • Mackey, Z.B.1    Ramos, W.2    Levin, D.S.3    Walter, C.A.4    McCarrey, J.R.5    Tomkinson, A.E.6
  • 30
    • 0029922114 scopus 로고    scopus 로고
    • Involvement of the Saccharomyces cerevisiae Hdf1 gene in DNA double strand break repair and recombination
    • Mages, G.J., Feldmann, H.M. and Winnacker, E.L. (1996) Involvement of the Saccharomyces cerevisiae Hdf1 gene in DNA double strand break repair and recombination. J. Biol. Chem., 271, 7910-7915.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7910-7915
    • Mages, G.J.1    Feldmann, H.M.2    Winnacker, E.L.3
  • 31
    • 0025346309 scopus 로고
    • A 21S enzyme complex from HeLa cells that functions in simian virus 40 DNA replication in vitro
    • Malkas, L.H., Hickey, R.J., Li, C.J., Pedersen, N. and Baril, E.F. (1990) A 21S enzyme complex from HeLa cells that functions in simian virus 40 DNA replication in vitro. Biochemistry, 29, 6362-6374.
    • (1990) Biochemistry , vol.29 , pp. 6362-6374
    • Malkas, L.H.1    Hickey, R.J.2    Li, C.J.3    Pedersen, N.4    Baril, E.F.5
  • 32
    • 0029954821 scopus 로고    scopus 로고
    • Mutations in two Ku homologs define a DNa end joining repair pathway in Saccharomyces cerevisiae
    • Milne, G.T., Jin, S.F., Shannon, K.B. and Weaver, D.T. (1996) Mutations in two Ku homologs define a DNA end joining repair pathway in Saccharomyces cerevisiae. Mol. Cell. Biol., 16, 4189-4198.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4189-4198
    • Milne, G.T.1    Jin, S.F.2    Shannon, K.B.3    Weaver, D.T.4
  • 33
    • 0022827675 scopus 로고
    • Mechanism of interaction between Ku protein and DNA
    • Mimori, T. and Hardin, J.A. (1986) Mechanism of interaction between Ku protein and DNA. J. Biol. Chem., 261, 10375-10379.
    • (1986) J. Biol. Chem. , vol.261 , pp. 10375-10379
    • Mimori, T.1    Hardin, J.A.2
  • 34
    • 0028850148 scopus 로고
    • The N-terminal domain of human DNA ligase I contains the nuclear localization signal and directs the enzyme to sites of DNA replication
    • Montecucco, A., Savini, E., Weighardt, F., Rossi, R., Ciarrocchi, G., Villa, A. and Biomonti, G. (1995) The N-terminal domain of human DNA ligase I contains the nuclear localization signal and directs the enzyme to sites of DNA replication. EMBO J. 14, 5379-5386.
    • (1995) EMBO J. , vol.14 , pp. 5379-5386
    • Montecucco, A.1    Savini, E.2    Weighardt, F.3    Rossi, R.4    Ciarrocchi, G.5    Villa, A.6    Biomonti, G.7
  • 35
    • 0029973775 scopus 로고    scopus 로고
    • A network approach to the systematic analysis of yeast gene function
    • Oliver, S. (1996) A network approach to the systematic analysis of yeast gene function. Trends Genet., 12, 241-242.
    • (1996) Trends Genet. , vol.12 , pp. 241-242
    • Oliver, S.1
  • 36
    • 0026045833 scopus 로고
    • Analysis of the mechanism of interaction of simian Ku protein with DNA
    • Paillard, S. and Strauss, F. (1991) Analysis of the mechanism of interaction of simian Ku protein with DNA. Nucleic Acids Res., 19, 5619-5624.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 5619-5624
    • Paillard, S.1    Strauss, F.2
  • 37
    • 0029919650 scopus 로고    scopus 로고
    • The DNA-binding protein Hdf1p (a putative Ku homolog) is required for maintaining normal telomere length in Saccharomyces cerevisiae
    • Porter, S.E., Greenwell, P.W., Ritchie, K.B. and Petes, T.D. (1996) The DNA-binding protein Hdf1p (a putative Ku homolog) is required for maintaining normal telomere length in Saccharomyces cerevisiae. Nucleic Acids Res., 24, 582-585.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 582-585
    • Porter, S.E.1    Greenwell, P.W.2    Ritchie, K.B.3    Petes, T.D.4
  • 38
    • 0028047308 scopus 로고
    • Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I
    • Prigent, C., Satoh, M.S., Daly, G., Barnes, D.E. and Lindahl, T. (1994) Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I. Mol. Cell. Biol., 14, 310-317.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 310-317
    • Prigent, C.1    Satoh, M.S.2    Daly, G.3    Barnes, D.E.4    Lindahl, T.5
  • 39
    • 0028074947 scopus 로고
    • Different active sites of mammalian DNA ligase I and ligase II
    • Roberis, E., Nash, R.A., Robins, P. and Lindahl, T. (1994) Different active sites of mammalian DNA ligase I and ligase II. J. Biol. Chem., 269, 3789-3792.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3789-3792
    • Roberis, E.1    Nash, R.A.2    Robins, P.3    Lindahl, T.4
  • 40
    • 0029817836 scopus 로고    scopus 로고
    • DNA ligase IV from HeLa cell nuclei
    • Robins, P. and Lindahl, T. (1996) DNA ligase IV from HeLa cell nuclei. J. Biol. Chem., 271, 24257-24261.
    • (1996) J. Biol. Chem. , vol.271 , pp. 24257-24261
    • Robins, P.1    Lindahl, T.2
  • 41
    • 0030033061 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Ku autoantigen homolog affects radiosensitivity only in the absence of homologous recombination
    • Siede, W., Friedl, A.A., Dianova, I., Eckardtschupp, F. and Friedberg, E.C. (1996) The Saccharomyces cerevisiae Ku autoantigen homolog affects radiosensitivity only in the absence of homologous recombination. Genetics, 142, 91-102.
    • (1996) Genetics , vol.142 , pp. 91-102
    • Siede, W.1    Friedl, A.A.2    Dianova, I.3    Eckardtschupp, F.4    Friedberg, E.C.5
  • 42
    • 0025202114 scopus 로고
    • Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange
    • Thompson, L.H., Brookman, K.W., Jones, N.J., Allen, S.A. and Carrano, A.V. (1990) Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange. Mol. Cell. Biol., 10, 6160-6171.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6160-6171
    • Thompson, L.H.1    Brookman, K.W.2    Jones, N.J.3    Allen, S.A.4    Carrano, A.V.5
  • 44
    • 0026489345 scopus 로고
    • DNA ligase I from Saccharomyces cerevisiae. Physical and biochemical characterization of the CDC9 gene product
    • Tomkinson, A.E., Tappe, N.J. and Friedberg, E.C. (1992) DNA ligase I from Saccharomyces cerevisiae. Physical and biochemical characterization of the CDC9 gene product. Biochemistry, 31, 11762-11771.
    • (1992) Biochemistry , vol.31 , pp. 11762-11771
    • Tomkinson, A.E.1    Tappe, N.J.2    Friedberg, E.C.3
  • 45
    • 0029971906 scopus 로고    scopus 로고
    • Hdf1, a yeast Ku protein homolog, is involved in illegitimate recombination, but not in homologous recombination
    • Tsukamoto, Y., Kato, J. and Ikeda, H. (1996) Hdf1, a yeast Ku protein homolog, is involved in illegitimate recombination, but not in homologous recombination. Nucleic Acids Res., 24, 2067-2072.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2067-2072
    • Tsukamoto, Y.1    Kato, J.2    Ikeda, H.3
  • 46
    • 0028363546 scopus 로고
    • Reconstitution of complete SV40 DNA replication with purified replication factors
    • Waga, S., Bauer, G. and Stillman, B. (1994) Reconstitution of complete SV40 DNA replication with purified replication factors. J. Biol. Chem., 269, 10923-10934.
    • (1994) J. Biol. Chem. , vol.269 , pp. 10923-10934
    • Waga, S.1    Bauer, G.2    Stillman, B.3
  • 47
    • 0027970892 scopus 로고
    • Mammalian DNA ligase II is highly homologous with vaccinia DNA ligase: Identification of the DNA ligase II active site for enzyme adenylate formation
    • Wang, Y.C.J., Burkhart, W.A., Mackey, Z.B., Moyer, M.B., Ramos, W., Husain, I., Chen, J.W., Besterman, J.M. and Tomkinson, A.E. (1994) Mammalian DNA ligase II is highly homologous with vaccinia DNA ligase: identification of the DNA ligase II active site for enzyme adenylate formation. J. Biol. Chem., 269, 31923-31928.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31923-31928
    • Wang, Y.C.J.1    Burkhart, W.A.2    Mackey, Z.B.3    Moyer, M.B.4    Ramos, W.5    Husain, I.6    Chen, J.W.7    Besterman, J.M.8    Tomkinson, A.E.9
  • 48
    • 0029024927 scopus 로고
    • Molecular cloning and expression of human cDNAs encoding a novel DNa ligase IV and DNa ligase III, an enzyme active in DNa repair and recombination
    • Wei, Y.-F. et al. (1995) Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination. Mol. Cell. Biol., 15, 3206-3216.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3206-3216
    • Wei, Y.-F.1
  • 49
    • 0029563009 scopus 로고
    • Telomeres: Beginning to understand the end
    • Zakian, V.A. (1995) Telomeres: beginning to understand the end. Science, 270, 1601-1607.
    • (1995) Science , vol.270 , pp. 1601-1607
    • Zakian, V.A.1


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