NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae

Nature

Volumn 414, Issue 6864, 2001, Pages 666-669

  Valencia, Maria ^a   Bentele, Marc ^b   Vaze, Moreshwar B ^a   Herrmann, Gernot ^b,c   Kraus, Eliayhu ^a   Lee, Sang Eun ^b,d   Schär, Primo ^b   Haber, James E ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF COLOGNE   (Germany)

^d University of Texas Health Science Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GENETIC ENGINEERING; PROTEINS; YEAST;

NUCLEUS;

DNA;

FUNGAL PROTEIN; HYBRID PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN NEJ1; UNCLASSIFIED DRUG;

DNA; PROTEIN;

ARTICLE; CYTOPLASM; DIPLOIDY; DNA REPAIR; DNA STRAND BREAKAGE; GENE DELETION; GENETIC RECOMBINATION; HAPLOIDY; MEIOSIS; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION;

DNA DAMAGE; DNA REPAIR; DNA, FUNGAL; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; GENES, MATING TYPE, FUNGAL; GREEN FLUORESCENT PROTEINS; HOMEODOMAIN PROTEINS; LUMINESCENT PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0035818985     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/414666a     Document Type: Article

References (29)

1. DNA breakage and repair
2. Mre11 and Ku70 interact in somatic cells, but are differentially expressed in early meiosis
3. Yeast cell-type regulation of DNA repair
4. Role of yeast SIR genes and mating type in channeling double-strand breaks to homologous and nonhomologous recombination pathways
5. Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
6. Saccharomyces cerevisiae LIF1: A function involved in DNA double-strand break repair related to mammalian XRCC4
7. Yeast DNA ligase IV mediates non-homologous DNA end joining
8. Hdf1, a yeast Ku-protein homologue, is involved in illegitimate recombination, but not in homologous recombination
9. Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae
10. Identification of a Saccharomyces cerevisiae Ku80 homologue: Roles in DNA double strand break rejoining and in telomeric maintenance
11. A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks
12. Identification of Saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair
13. Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways
14. Effects of mutations of RAD50, RAD51, RAD52, and related genes on illegitimate recombination in Saccharomyces cerevisiae
15. Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae
16. Mating-type gene switching in Saccharomyces cerevisiae
17. Ploidy regulation of gene expression
18. Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast
19. A 700 bp cis-acting region controls mating-type dependent recombination along the entire left arm of yeast chromosome III
20. Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks
21. PSORT: A program for detecting sorting signals in proteins and predicting their subcellular localization
22. A comprehensive two-hybrid analysis to explore the yeast protein interactome
23. Nej1p, a cell type-specific regulator of nonhomologous end joining in yeast
24. A DNA microarray-based genetic screen for nonhomologous end-joining mutants in Saccharomyces cerevisiae
25. NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the Ligase IV pathway
26. Yeast-enhanced green fluorescent protein (yEGFP) a reporter of gene expression in Candida albicans
27. Saccharomyces Ku70, Mre11/Rad50 and RPA proteins regulate adaptation to G2/M arrest DNA damage
28. A cDNA encoding a human CCAAT-binding protein cloned by functional complementation in yeast
29. Genomic expression programs in the response of yeast cells to environmental changes