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Volumn 160, Issue 1, 2002, Pages 115-122

Hyperglycemia induces PAI-1 gene expression in adipose tissue by activation of the hexosamine biosynthetic pathway

Author keywords

Diabetes mellitus; Glucose; Hexosamine biosynthetic pathway; Insulin resistance; Obesity; Plasminogen activator inhibitor type 1

Indexed keywords

GLUCOSAMINE; GLUCOSE; HEXOSAMINE; INSULIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; SODIUM CHLORIDE; SOMATOSTATIN;

EID: 0036145255     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(01)00574-3     Document Type: Article
Times cited : (59)

References (53)
  • 2
    • 0030938616 scopus 로고    scopus 로고
    • Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidaemia and atherosclerosis
    • (1997) Neth J Med , vol.50 , Issue.5 , pp. 191-197
    • DeFronzo, R.A.1
  • 9
    • 0029153839 scopus 로고
    • Plasminogen activator inhibitor 1 (PAI-1) in plasma: Its role in thrombotic disease
    • (1995) Thromb Haemost , vol.74 , Issue.1 , pp. 71-76
    • Wiman, B.1
  • 15
    • 0031987937 scopus 로고    scopus 로고
    • Vascular cell-derived fibrinolytic regulators and atherothrombotic vascular disorders
    • (1998) Int J Mol Med , vol.1 , Issue.2 , pp. 399-408
    • Shen, G.X.1
  • 19
    • 0028012539 scopus 로고
    • Augmentation of the synthesis of plasminogen activator inhibitor type-1 by precursors of insulin. A potential risk factor for vascular disease
    • (1994) Circulation , vol.89 , Issue.1 , pp. 321-330
    • Nordt, T.K.1    Schneider, D.J.2    Sobel, B.E.3
  • 30
    • 0025855139 scopus 로고
    • Traxinger RR: Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance
    • (1991) J Biol Chem , vol.266 , Issue.8 , pp. 4706-4712
    • Marshall, S.1    Bacote, V.2
  • 35
  • 40
    • 0025376250 scopus 로고
    • Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats
    • (1990) J Clin Invest , vol.85 , Issue.6 , pp. 1785-1792
    • Rossetti, L.1    Giaccari, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.