Insulin receptor-related receptor is expressed in pancreatic β-cells and stimulates tyrosine phosphorylation of insulin receptor substrate-1 and- 2

Diabetes

Volumn 48, Issue 6, 2000, Pages 1237-1244

  Hirayama, Isao ^a,b   Tamemoto, Hiroyuki ^a   Yokota, Hiromi ^a   Kubo, Suely Kunimi ^a   Wang, Jie ^a   Kuwano, Hiroyuki ^b   Nagamachi, Yukio ^b   Takeuchi, Toshiyuki ^a   Izumi, Tetsuro ^a  

^a GUNMA UNIVERSITY   (Japan)

^b GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; INSULIN; INSULIN RECEPTOR RELATED RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; PROTEIN TYROSINE KINASE; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL DIFFERENTIATION; CONTROLLED STUDY; INSULIN RESISTANCE; INSULIN SYNTHESIS; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CATALYTIC DOMAIN; CHO CELLS; CRICETINAE; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISLETS OF LANGERHANS; LIGANDS; MICE; MICE, INBRED BALB C; MICE, INBRED STRAINS; PHOSPHOPROTEINS; PHOSPHORYLATION; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TYROSINE;

EID: 0344517365     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.6.1237     Document Type: Article

References (48)

1. Bonner-Weir S: Regulation of pancreatic β-cell mass in vivo. Recent Prog Horm Res 49:91-104, 1994
2. Vinik A, Pittenger G, Rafaeloff R, Rosenberg L, Duguid W: Determinants of pancreatic islet cell mass: a balance between neogenesis and senescence/ apoptosis. Diabetes Rev 4:235-263, 1996
3. Karasik A, Hattori M: Use of animal models in the study of diabetes. In Joslin's Diabetes Mellitus. 13th ed. Kahn CR, Weir GC, Eds. Malvern, PA, Lea & Febiger, 1994, p. 317-350
4. Miyaura C, Chen L, Appel M, Alam T, Inman L, Hughes SD, Milburn JL, Unger RH, Newgard CB: Expression of reg/PSP, a pancreatic exocrine gene: relationship to changes in islet β-cell mass. Mol Endocrinol 5:226-234,1991
5. Montaña E, Bonner-Weir S, Weir GC: Transplanted beta cell response to increased metabolic demand: changes in beta cell replication and mass. J Clin Invest 93:1577-1582, 1994
6. Terauchi Y, Iwamoto K, Tamemoto H, Komeda K, Ishii C, Kanazawa Y, Asanuma N, Aizawa T, Akanuma Y, Yasuda K, Kodama T, Tobe K, Yazaki Y, Kadowaki T: Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and β cell glucokinase genes: genetic reconstitution of diabetes as a polygenic disease. J Clin Invest 99:861-866, 1997
7. van der Geer P, Hunter T, Lindberg RA: Receptor protein-tyrosine kinases and their signal transduction pathways. Annu Rev Cell Biol 10:251-337, 1994
8. Withers DJ, Gutierrez JS, Towery H, Burks DJ, Ren J-M, Previs S, Zhang Y, Bernal D, Pons S, Shulman GI, Bonner-Weir S, White MF: Disruption of IRS-2 causes type 2 diabetes in mice. Nature 391:900-904, 1998
9. Myers MGJ, White MF: Insulin signal transduction and the IRS proteins. Annu Rev Pharmacol Toxicol 36:615-658, 1996
10. Ihle JN, Kerr IM: Jaks and Stats in signaling by the cytokine receptor super-family. Trends Genet 11:69-74, 1995
11. Brelje TC, Scharp DW, Lacy PE, Ogren L, Talamantes F, Robertson M, Friesen HG, Sorenson RL: Effect of homologous placental lactogens, prolactins, and growth hormones on islet B-cell division and insulin secretion in rat, mouse, and human islets: implication for placental lactogen regulation of islet function during pregnancy. Endocrinology 132:879-887, 1993
12. Hirayama I, Yi Z, Izumi S, Arai I, Suzuki W, Nagamachi Y, Kuwano H, Takeuchi T, Izumi T: Genetic analysis of obese diabetes in the TSOD mouse. Diabetes 48: 1183-1191, 1999
13. Gotoh M, Maki T, Kiyoizumi T, Satomi S, Monaco AP: An improved method for isolation of mouse pancreatic islets. Transplantation 40:437-438, 1985
14. Radvanyi F, Christgau S, Baekkeskov S, Julicoeur C, Hanahan D: Pancreatic β cells cultured from individual preneoplastic foci in a multistage tumorigenesis pathway: a potentially general technique for isolating physiologically representative cell lines. Mol Cell Biol 13:4223-4232, 1993
15. Miyazaki J, Araki K, Yamato E, Ikegami H, Asano T, Shibasaki Y, Oka Y, Yamamura K: Establishment of a pancreatic βcell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms Endocrinology 127:126-132, 1990
16. Hamaguchi K, Leiter EH: Comparison of cytokine effects on mouse pancreatic α-cell and β-cell lines: viability, secretory function, and MHC antigen expression. Diabetes 39:415-425, 1990
17. Efrat S, Linde S, Kofod H, Spector D, Delannoy M, Grant S, Hanahan D, Baekkeskov S: Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. Proc Natl Acad Sci U S A 85:9037-9041, 1988
18. Gazdar AF, Chick WL, Oie HK, Sims HL, King DL, Weir GC, Lauris V: Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor. Proc Natl Acad Sci U S A 77: 3519-3523, 1980
19. 996. J Biol Chem 265:14777-14783, 1990
20. Izumi T, Walker DH, Maller JL: Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity. Mol Biol Cell 3:927-939, 1992
21. Ozaki K, Takada N, Tsujimoto K. Tsuji N, Kawamura T, Muso E, Ohta M, Itoh N: Localization of insulin receptor-related receptor in the rat kidney. Kidney Int 52:694-698, 1997
22. Izumi T, Saeki Y, Akanuma Y, Takaku F, Kasuga M: Requirement for receptor-intrinsic tyrosine kinase activities during ligand-induced membrane ruffling of KB cells: essential sites of src-related growth factor receptor kinases. J Biol Chem 263: 10386-10393, 1988
23. Sun XJ, Wang LM, Zhang Y, Yenush L, Myers MGJ, Glasheen E, Lane WS, Pierce JH, White MF: Role of IRS-2 in insulin and cytokine signalling. Nature 377:173-177, 1995
24. Lamphere L, Lienhard GE: Components of signaling pathways for insulin and insulin-like growth factor-I in muscle myoblasts and myotubes. Endocrinology 131:2196-2202, 1992
25. Ullrich A, Bell JR, Chen EY, Herrera R, Petruzzelli LM, Dull TJ, Gray A, Coussens L, Liao Y-C, Tsubokawa M, Mason A, Seeburg PH, Grunfeld C, Rosen OM, Ramachandran J: Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature 313:756-761, 1985
26. Maruta H, Holden J, Sizeland A, D'Abaco G: The residues of ras and rap proteins that determine their GAP specificities. J Biol Chem 266:11661-11668, 1991
27. Hovens CM, Stacker SA, Andres A-C, Harpur AG, Ziemiecki A, Wilks AF: RYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs. Proc Natl Acad Sci U S A 89:11818-11822, 1992
28. Shier P, Watt VM: Primary structure of a putative receptor for a ligand of the insulin family. J Biol Chem 264:14605-14608, 1989
29. Bates CM, Merenmies JM, Kelly-Spratt KS, Parada LF: Insulin receptor-related receptor expression in non-A intercalated cells in the kidney. Kidney Int 51:674-681, 1997
30. Mathi SK, Chan J, Watt VM: Insulin receptor-related receptor messenger ribonucleic acid: quantitative distribution and localization to subpopulation of epithelial cells in stomach and kidney. Endocrinology 136:4125-4132, 1995
31. Tsujimoto K, Tsuji N, Ozaki K, Ohta M, Itoh N: Insulin receptor-related receptor messenger ribonucleic acid in the stomach is focally expressed in the enterochromaffin-like cells. Endocrinology 136:558-561, 1995
32. Reinhardt RR, Chin E, Zhang B, Roth RA, Bondy CA: Selective coexpression of insulin receptor-related receptor (IRR) and TRK in NGF-sensitive neurons. J Neurosci 14:4674-4683, 1994
33. Tsujimoto K, Tsuji N, Ozaki K, Minami M, Satoh M, Itoh N: Expression of insulin receptor-related receptor mRNA in the rat brain is highly restricted to forebrain cholinergic neurons. Neurosci Lett 188:105-108, 1995
34. Ozaki K: Insulin receptor-related receptor in rat islets of Langerhans. Eur J Endocrinol 139:244-247, 1998
35. Thomas KA: Vascular endothelial growth factor, a potent and selective angiogenic agent. J Biol Chem 271:603-306, 1996
36. Davis S, Aldrich TH, Jones PF, Acheson A, Compton DL, Jain V, Ryan TE, Bruno J, Radziejewski C, Maisonpierre PC, Yancopoulos GD: Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 87:1161-1169, 1996
37. Hanks SK, Hunter T: The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J 9:576-596, 1995
38. Jui H-Y, Suzuki Y, Accili D, Taylor SI: Expression of a cDNA encoding the human insulin receptor-related receptor. J Biol Chem 269:22446-22452, 1994
39. Zhang B, Roth RA: The insulin receptor-related receptor tissue expression, ligand binding specificity, and signaling capabilities. J Biol Chem 267: 18320-18328, 1992
40. Liu J-P, Baker J, Perkins AS, Robertson EJ, Efstratiadis A: Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75:59-72, 1993
41. Accili D: Insulin receptor knock-out mice. Trends Endocrinol Metab 8:101-104, 1997
42. Duvillié B, Cordonnier N, Deltour L, Dandoy-Dron F, Itier J-M, Monthioux E, Jami J, Joshi RL, Bucchini D: Phenotypic alterations in insulin-deficient mutant mice. Proc Natl Acad Sci U S A 94:5137-5140, 1997
43. Bravo DA, Gleason JB, Sanchez RI, Roth RA, Fuller RS: Accurate and efficient cleavage of the human insulin proreceptor by the human proprotein-processing protease furin: characterization and kinetic parameters using the purified, secreted soluble protease expressed by a recombinant baculovirus. J Biol Chem 269:25830-25837, 1994
44. Kayo T, Sawada Y, Suda M, Konda Y, Izumi T, Tanaka S, Shibata H, Takeuchi T: Proprotein-processing endoprotease furin controls growth of pancreatic β-cells. Diabetes 46:1296-1304, 1997
45. Stuart CA: Characterization of a novel insulin receptor from stingray liver. J Biol Chem 263:7881-7886, 1988
46. Olson TS, Lane MD: Post-translational acquisition of insulin binding activity by the insulin prorecepton correlation to recognition by autoimmune antibody. J Biol Chem 262:6816-6822, 1987
47. Baserga R: Oncogenes and the strategy of growth factors. Cell 79:927-930, 1994
48. Zhou-Li F, D'Ambrosio C, Li S, Surmacz E, and Baserga R: Association of insulin receptor substrate 1 with simian virus 40 large T antigen. Mol Cell Biol 15:4232-4239, 1995