Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells

Journal of Neuroscience Research

Volumn 51, Issue 3, 1998, Pages 293-308

  Kruman, Inna ^a   Guo, Qing ^a   Mattson, Mark P ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Caspase inhibitor; Fura 2; Lipid peroxidation; Nerve growth factor; Nitric oxide; Permeability transition; Peroxynitrite; Uric acid

Indexed keywords

CALCIUM ION; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FURA 2; NERVE GROWTH FACTOR; NITRIC OXIDE; PEROXYNITRITE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RHODAMINE 123; STAUROSPORINE; URIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CELL STRAIN; CELL TYPE; CONTROLLED STUDY; LIPID PEROXIDATION; MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; CALCIUM; CHELATING AGENTS; ENZYME INHIBITORS; MITOCHONDRIA; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; STAUROSPORINE;

EID: 0032006868     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19980201)51:3<293::AID-JNR3>3.0.CO;2-B     Document Type: Article

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