Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells

Journal of Clinical Investigation

Volumn 99, Issue 1, 1997, Pages 144-150

  Matsuoka, Taka Aki ^a   Kajimoto, Yoshitaka ^a   Watada, Hirotaka ^a   Kaneto, Hideaki ^a   Kishimoto, Michihiko ^a   Umayahara, Yutaka ^a   Fujitani, Yoshio ^a   Kamada, Takenobu ^a   Kawamori, Ryuzo ^b   Yamasaki, Yoshimitsu ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

Author keywords

gene expression regulation; glycosylation; homeodomain protein; oxidative stress; transcription factors

Indexed keywords

ACETYLCYSTEINE; AMINOGUANIDINE; HOMEODOMAIN PROTEIN; INSULIN;

ANIMAL CELL; ARTICLE; DNA BINDING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GLUCOSE BLOOD LEVEL; GLYCOSYLATION; INSULIN METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS;

EID: 0031020374     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119126     Document Type: Article

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