Chemistry, biological properties and SAR analysis of quinoxalinones

Mini-Reviews in Medicinal Chemistry

Volumn 6, Issue 11, 2006, Pages 1179-1200

  Carta, A ^a   Piras, S ^a   Loriga, G ^a   Paglietti, G ^a  

^a UNIVERSITY OF SASSARI   (Italy)

Author keywords

AMPA antagonists; Anti cancer activity; Antiallergic activity; Antimicrobial activity; Antithrombotic activity; Chemical syntheses and reactions; GlyN antagonists; Pgp antagonists; Quinoxalin 2(3) ones; Quinoxalin 2,3 diones; SAR studies

Indexed keywords

1 LUPINYL 3 METHYLQUINOXALINONE DERIVATIVE; 1,2,3,4 TETRAHYDROQUINOLINE DERIVATIVE; 2 (4 BENZYL 3 OXO 3,4 DIHYDROQUINOXALIN 2 YL METHOXY) N PHENYLBENZAMIDE; 2 ETHYL 7 FLUORO 1,2,3,4 TETRAHYDRO 3 OXO 1 QUINOXALINECARBOXYLIC ACID ISOPROPYL ESTER; 2,3 QUINOXALINEDIONE DERIVATIVE; 3 CYCLOPROPYLETHYNYL 3 TRIFLUOROMETHYLQUINOXALIN 2 ONE DERIVATIVE; 3 ETHYL 6 METHOXY 1,2,3,4 TETRAHYDROQUINOXALIN 2 ONE; 3 PHENOXYMETHYLQUINOXALINE DERIVATIVE; 5 CHLORO 7 TRIFLUOROMETHYL 2,3 QUINOXALINEDIONE; 6 CHLORO 1 LUPINYL 3 METHYLQUINOXALINONE; 6,7 DICHLORO 5 NITRO 2,3 QUINOXALINEDIONE; 6,7 DIMETHYL 5 NITRO 2,3 QUINOXALINEDIONE; ANTIALLERGIC AGENT; ANTICOAGULANT AGENT; DOXORUBICIN; EFAVIRENZ; ETOPOSIDE; GLUTAMATE RECEPTOR ANTAGONIST; IMIDAZO[1,2 A]QUINOXALINONE DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PANADIPLON; PYRROLO[1,2 A]QUINOLINE DERIVATIVE; QUINOXALINE; QUINOXALINE 2 BENZYLOXY 3 (2 BENZAMIDEPHENOXYMETHYL) 7 TRIFLUOROMETHYLQUINOXALINE; QUINOXALINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINBLASTINE; VINCRISTINE;

ANALGESIA; ANTIBACTERIAL ACTIVITY; ANTICOAGULATION; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; AVOIDANCE BEHAVIOR; CANCER CELL CULTURE; CANDIDA ALBICANS; CANDIDA PARAPSILOSIS; CLINICAL TRIAL; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG POTENTIATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; LEUKEMIA P 388; LIVER DYSFUNCTION; LIVER TOXICITY; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NEUROPROTECTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PSEUDOMONAS AERUGINOSA; REVIEW; RHESUS MONKEY; SPASMOLYSIS; STRUCTURE ACTIVITY RELATION; TRANQUILIZING ACTIVITY; VIBRIO ALGINOLYTICUS;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; QUINOXALINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33750711044     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955706778742713     Document Type: Review

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