Structure-activity studies of substituted quinoxalinones as multiple-drug-resistance antagonists

Journal of Medicinal Chemistry

Volumn 44, Issue 4, 2001, Pages 594-601

  Lawrence, D S ^a   Copper, J E ^a   Smith, C D ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BROMOMETHYLQUINOXALINONE; GLYCOPROTEIN P; PHENOXYMETHYLQUINOXALINONE; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CELL STRAIN MCF 7; CONTROLLED STUDY; DOSE RESPONSE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IC 50; MULTIDRUG RESISTANCE; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; P-GLYCOPROTEIN; QUINOXALINES; TUMOR CELLS, CULTURED;

EID: 0035865923     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000282d     Document Type: Article

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